scholarly journals Psoriasis as risk factor for non-ischemic dilated cardiomyopathy: a population-based cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Abbas Alshami ◽  
Nasam Alfraji ◽  
Steven Douedi ◽  
Swapnil Patel ◽  
Mohammad Hossain ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Large Population ◽  
Autoimmune Disorder ◽  
International Classification Of Diseases ◽  
The United States ◽  
Population Based ◽  
Skin Condition ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Non Ischemic Dilated Cardiomyopathy

Abstract Background Psoriasis is a chronic inflammatory skin condition commonly associated with psoriatic arthritis, malignancy, diabetes, inflammatory bowel disease, and cardiovascular disease. Several reports and studies have reported an association between psoriasis and non-ischemic dilated cardiomyopathy (NIDCM). We aim to study the relationship between psoriasis and non-ischemic dilated cardiomyopathy in a large population-based study. Methods We utilized the Healthcare Cost and Utilization Project National Inpatient Sample 2017 database, which represents a 20% sample of all payer hospitalizations in the United States. We investigated hospitalizations for patients aged 18 years old or older with diagnoses of any type of psoriasis and non-ischemic dilated cardiomyopathy. Psoriasis, cardiomyopathy, and other comorbidities were identified through their international classification of diseases, 10th revision codes recorded in the discharge record for each hospitalization. Results Of a total of 6,084,184 all-cause admissions, 0.5% were admissions for patients with psoriasis (n = 32,807). Of the patients with and without psoriasis who had non-ischemic dilated cardiomyopathy, after adjusting for age, sex, race, diabetes mellitus, hypertension, alcohol abuse, cocaine abuse, arrhythmias, and obesity in a multivariate analysis, the presence of psoriasis was not significantly associated with non-ischemic dilated cardiomyopathy. Conclusion Psoriasis is a chronic autoimmune disorder which carries a higher cardiovascular events and more prevalent traditional atherosclerotic risk factors in comparison to the general population. However, association with non-ischemic cardiomyopathy or NIDCM in particular has not been studied sufficiently. Our study, being one of the first larger studies to assess this correlation, indicated no relationship between psoriasis and non-ischemic dilated cardiomyopathy.

scholarly journals Correction to: Psoriasis as risk factor for non-ischemic dilated cardiomyopathy: a population-based cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Abbas Alshami ◽  
Nasam Alfraji ◽  
Steven Douedi ◽  
Swapnil Patel ◽  
Mohammad Hossain ◽  
...  
Keyword(s):  
Risk Factor ◽  
Dilated Cardiomyopathy ◽  
Population Based ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Non Ischemic Dilated Cardiomyopathy

An amendment to this paper has been published and can be accessed via the original article.

scholarly journals Prevalence of systemic lupus erythematosus in Spain: higher than previously reported in other countries?

Rheumatology ◽  
2020 ◽  
Vol 59 (9) ◽  
pp. 2556-2562 ◽  
Author(s):  
Raúl Cortés Verdú ◽  
José M Pego-Reigosa ◽  
Daniel Seoane-Mato ◽  
Mercedes Morcillo Valle ◽  
Deseada Palma Sánchez ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Adult Population ◽  
Geographical Area ◽  
Geographic Origin ◽  
The United States ◽  
Epidemiological Studies ◽  
Population Based ◽  
Cross Sectional Study ◽  
Medical Visit ◽  
Cross Sectional

Abstract Objectives Prevalence of SLE varies among studies, being influenced by study design, geographical area and ethnicity. Data about the prevalence of SLE in Spain are scarce. In the EPISER2016 study, promoted by the Spanish Society of Rheumatology, the prevalence estimate of SLE in the general adult population in Spain has been updated and its association with sociodemographic, anthropometric and lifestyle variables has been explored. Methods Population-based multicentre cross-sectional study, with multistage stratified and cluster random sampling. Participants were contacted by telephone to carry out a questionnaire for the screening of SLE. Investigating rheumatologists evaluated positive results (review of medical records and/or telephone interview, with medical visit if needed) to confirm the diagnosis. To calculate the prevalence and its 95% CI, the sample design was taken into account and weighing was calculated considering age, sex and geographic origin. Multivariate logistic regression models were defined to analyse which sociodemographic, anthropometric and lifestyle variables included in the telephone questionnaire were associated with the presence of SLE. Results 4916 subjects aged 20 years or over were included. 16.52% (812/4916) had a positive screening result for SLE. 12 cases of SLE were detected. The estimated prevalence was 0.21% (95% CI: 0.11, 0.40). SLE was more prevalent in the rural municipalities, with an odds ratio (OR) = 4.041 (95% CI: 1.216, 13.424). Conclusion The estimated prevalence of SLE in Spain is higher than that described in most international epidemiological studies, but lower than that observed in ethnic minorities in the United States or the United Kingdom.

scholarly journals Socio-Economic Status and Prevalence of Self-Reported Osteoporosis in Tehran: Results from a Large Population-Based Cross-Sectional Study (Urban HEART-2)

2018 ◽  
Vol 95 (5) ◽  
pp. 682-690 ◽  
Author(s):  
M. Asadi-Lari ◽  
Y. Salimi ◽  
M. R. Vaez-Mahdavi ◽  
S. Faghihzadeh ◽  
A. A. Haeri Mehrizi ◽  
...  
Keyword(s):  
Economic Status ◽  
Large Population ◽  
Population Based ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Socio Economic Status

scholarly journals Multimorbidity as an important issue among women: results of a gender difference investigation in a large population-based cross-sectional study in West Asia

BMJ Open ◽  
2017 ◽  
Vol 7 (5) ◽  
pp. e013548 ◽  
Author(s):  
Masoomeh Alimohammadian ◽  
Azam Majidi ◽  
Mehdi Yaseri ◽  
Batoul Ahmadi ◽  
Farhad Islami ◽  
...  
Keyword(s):  
Gender Difference ◽  
Large Population ◽  
Population Based ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Daytime napping is associated with retinal microcirculation: a large population-based study in China

SLEEP ◽  
2021 ◽  
Author(s):  
Xin Liu ◽  
Guowei Wang ◽  
Xiaoyan Wang ◽  
Yueye Wang ◽  
Yan Min ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Large Population ◽  
Vascular Diseases ◽  
Population Based ◽  
Cross Sectional Study ◽  
Cubic Spline ◽  
Fundus Photography ◽  
Cross Sectional ◽  
Retinal Microcirculation ◽  
Cubic Spline Curve

Abstract Study Objectives To investigate the association between daytime napping and retinal microcirculation. Methods This is a cross-sectional study from a prospective population-based cohort. 2,662 participants were recruited after quota sampling. Information on napping was collected through face-to-face interviews. Retinal vascular calibers (RVCs), including central retinal arteriolar equivalent (CRAE), central retinal venular equivalent (CRVE), and arterio-to-venous ratio (AVR), were obtained from fundus photography. Multivariate regression and restricted cubic spline curve were performed to determine the association between RVCs and daytime napping duration. Results 56.4% participants reported daytime napping regularly. Compared to no nap, daytime nap was related to higher CRAE, with nap duration of 0.5–1 h showing the most significant association. 0.5–1 h daytime nappers displayed an average of 4.18 µm (95% confidence interval [CI] 2.45–5.91, p < 0.001) wider CRAE than non-nappers after adjustment. No significant association was found between CRVE and daytime napping. Moreover, individuals with 0.5–1 h daytime napping had a lower risk for AVR reduction (odds ratio [OR] 0.70, 95% confidence interval [CI] 0.56–0.86, p = 0.001) than non-nappers. Similar association persisted in non-hypertensive population. Restricted cubic spline indicated a J-shaped relationship between AVR reduction and nap duration. Conclusion Retinal microcirculation was positively associated with self-reported 0.5–1 h daytime napping. Better indicators of retinal microcirculation were probably related to nap duration in a J-shaped manner. Also, the possibly beneficial role of 0.5–1 h daytime napping on retinal microcirculation might be independent of clinically diagnosed vascular diseases.

Abstract 46: Outcomes of Thrombolysis for In-hospital Stroke: A Population-Based Study of US Hospitals

Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Yogesh Moradiya ◽  
Steven R Levine
Keyword(s):  
Bleeding Risk ◽  
International Classification Of Diseases ◽  
Functional Independence ◽  
Population Based ◽  
Cross Sectional Study ◽  
Tube Placement ◽  
Gi Bleeding ◽  
Inpatient Mortality ◽  
Cross Sectional ◽  
Co Morbidity

Background: In-hospital stroke (IHS) may differ from out-of-hospital stroke (OHS) in terms of mechanism, risk factors and outcomes. Objective/Hypothesis: We compared IHS and OHS treated with systemic or intra-arterial thrombolysis from a large national cohort in a cross-sectional study to further clarify these differences. Our hypothesis was that there would be poorer patient outcomes associated with IHS than OHS. Methods: Nationwide inpatient sample (NIS) for years 2005-2009 was searched for stroke cases treated with thrombolysis by using International Classification of Diseases-9 codes. Patients treated on the day of admission were classified as OHS. Primary outcome measures were inpatient mortality and functional independence at discharge as indicated by discharge to home (self-care). Secondary outcomes included intracranial hemorrhage (ICH), GI bleeding, tracheostomy and gastrostomy tube placement. IHS as an independent predictor of outcomes was studied using multivariate logistic regression. Results: IHS comprised of 1,054 (11.3%) cases of all (N=9,353) thrombolysed ischemic strokes. IHS was associated with higher co-morbidity profile and higher rates of acute medical conditions. In unadjusted analyses, IHS had higher inpatient mortality (18.8% vs. 10.9%, p<0.001) and lower rate of functional independence at discharge (21.7 vs. 28.6%, p<0.001). While IHS had higher rates of GI bleeding, tracheostomy and gastrostomy, the rate of ICH in IHS was similar to that of OHS (4.6% vs. 4.8%, p=0.807). After controlling for demographics, hospital characteristics and co-morbidities, inpatient mortality (adj. OR:1.82; 95% CI:1.53-2.16, p<0.001) and favorable discharge outcome (adj. OR:0.80; 95% CI:0.68-0.94, p=0.007)) remained significantly worse in IHS while the rate of ICH (adj. OR:0.91; 95% CI:0.67-1.23) remained similar to that of OHS. Conclusions: Thrombolysis in IHS is associated with worse outcomes and higher rates of inpatient medical complications compared to OHS, likely due to their higher co-morbidities and additional medical reasons for hospital admission. In spite of presumed higher bleeding risk in IHS, thrombolytic use is not associated with higher rate of ICH among IHS.

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