scholarly journals Clinical characteristics of inpatients with coronavirus disease 2019 (COVID-19) in Sichuan province

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Wen Wang ◽  
Lei Chen ◽  
Qiao He ◽  
Mingqi Wang ◽  
Mei Liu ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Clinical Features ◽  
Medical Records ◽  
Clinical Characteristics ◽  
Sichuan Province ◽  
Chest Ct ◽  
Shortness Of Breath ◽  
Course Of Disease ◽  
West China ◽  
Radiologic Abnormality

Abstract Background The outbreak of COVID-19 has resulted in serious concerns in China and abroad. To investigate clinical features of confirmed and suspected patients with COVID-19 in west China, and to examine differences between severe versus non-severe patients. Methods Patients admitted for COVID-19 between January 21 and February 11 from fifteen hospitals in Sichuan Province, China were included. Experienced clinicians trained with methods abstracted data from medical records using pre-defined, pilot-tested forms. Clinical characteristics between severe and non-severe patients were compared. Results Of the 169 patients included, 147 were laboratory-confirmed, 22 were suspected. For confirmed cases, the most common symptoms from onset to admission were cough (70·7%), fever (70·5%) and sputum (33·3%), and the most common chest CT patterns were patchy or stripes shadowing (78·0%); throughout the course of disease, 19·0% had no fever, and 12·4% had no radiologic abnormality; twelve (8·2%) received mechanical ventilation, four (2·7%) were transferred to ICU, and no death occurred. Compared to non-severe cases, severe ones were more likely to have underlying comorbidities (62·5% vs 26·2%, P = 0·001), to present with cough (92·0% vs 66·4%, P = 0·02), sputum (60·0% vs 27·9%, P = 0·004) and shortness of breath (40·0% vs 8·2%, P <  0·0001), and to have more frequent lymphopenia (79·2% vs 43·7%, P = 0·003) and eosinopenia (84·2% vs 57·0%, P = 0·046). Conclusions The symptoms of patients in west China were relatively mild, and an appreciable proportion of infected cases had no fever, warranting special attention.

scholarly journals Identifying common baseline clinical features of COVID-19: a scoping review

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e041079 ◽  
Author(s):  
Daniela Ferreira-Santos ◽  
Priscila Maranhão ◽  
Matilde Monteiro-Soares
Keyword(s):  
Clinical Features ◽  
Scoping Review ◽  
Clinical Characteristics ◽  
Meta Analysis ◽  
Research Question ◽  
Adult Patients ◽  
Shortness Of Breath ◽  
The Moment ◽  
Different Characteristics ◽  
Diagnosis Of Infection

ObjectivesOur research question was: what are the most frequent baseline clinical characteristics in adult patients with COVID-19? Our major aim was to identify common baseline clinical features that could help recognise adult patients at high risk of having COVID-19.DesignWe conducted a scoping review of all the evidence available at LitCovid, until 23 March 2020.SettingStudies conducted in any setting and any country were included.ParticipantsStudies had to report the prevalence of sociodemographic characteristics, symptoms and comorbidities specifically in adults with a diagnosis of infection by SARS-CoV-2.ResultsIn total, 1572 publications were published on LitCovid. We have included 56 articles in our analysis, with 89% conducted in China and 75% containing inpatients. Three studies were conducted in North America and one in Europe. Participants’ age ranged from 28 to 70 years, with balanced gender distribution. The proportion of asymptomatic cases were from 2% to 79%. The most common reported symptoms were fever (4%–99%), cough (4%–92%), dyspnoea/shortness of breath (1%–90%), fatigue (4%–89%), myalgia (3%–65%) and pharyngalgia (2%–61%), while regarding comorbidities, we found cardiovascular disease (1%–40%), hypertension (0%–40%) and cerebrovascular disease (1%–40%). Such heterogeneity impaired the conduction of meta-analysis.ConclusionsThe infection by COVID-19 seems to affect people in a very diverse manner and with different characteristics. With the available data, it is not possible to clearly identify those at higher risk of being infected with this condition. Furthermore, the evidence from countries other than China is, at the moment, too scarce.

Anorexia Nervosa in Males: A Report of 12 Cases

1993 ◽  
Vol 27 (3) ◽  
pp. 512-517 ◽  
Author(s):  
S. W. Touyz ◽  
E. M. Kopec-Schrader ◽  
P. J. V. Beumont
Keyword(s):  
Anorexia Nervosa ◽  
Retrospective Analysis ◽  
Clinical Features ◽  
Medical Records ◽  
Clinical Characteristics ◽  
Female Patients ◽  
Male Patients

The demographic and clinical features of 12 male patients with anorexia nervosa were investigated by means of a retrospective analysis of their medical records. The clinical characteristics of the male patients were found to be remarkably similar to those reported for female patients and our findings concur with previously published literature. There appears however to be a greater tendency to exercise excessively. The importance of recognising anorexia nervosa in males is emphasized.

scholarly journals Identifying baseline clinical features of people with COVID-19

2020 ◽  
Author(s):  
Daniela Ferreira-Santos ◽  
Priscila Maranhao ◽  
Matilde Monteiro-Soares
Keyword(s):  
Cardiovascular Disease ◽  
North America ◽  
Cerebrovascular Disease ◽  
Clinical Features ◽  
Scoping Review ◽  
Clinical Characteristics ◽  
Meta Analysis ◽  
Demographic Characteristics ◽  
Shortness Of Breath ◽  
Different Characteristics

Objectives: To describe baseline clinical characteristics of adult patients with COVID-19. Methods: We conducted a scoping review of the evidence available at LitCovid, until March 23th, 2020, and selected articles that reported the prevalence of socio-demographic characteristics, symptoms and co-morbidities in adults with COVID-19. Results: In total, 1 572 publications were published on LitCovid. We have included 56 articles in our analysis, with 89% conducted in China, and 75% contained inpatients. Three studies were conducted in North America and one in Europe. Participants age ranged from 28 to 70 years, with balanced gender distribution. Proportion of asymptomatic cases were from 2 to 79%. The most common reported symptoms were fever [4-99%], cough [4-92%], dyspnoea/shortness of breath [1-90%], fatigue 4-89%], myalgia [3-65%], and pharyngalgia [2-61%], while regarding co-morbidities we found cardiovascular disease [1-40%], hypertension [0-40%] and cerebrovascular disease [1-40%]. Such heterogeneity impairs the conduction of meta-analysis. Conclusions: The infection by COVID-19 seems to affect people in a very diverse manner and with different characteristics. With the available data it is not possible to clearly identify those at higher risk of being infected with this condition. Furthermore, the evidence from countries other than China is, at the day, too scarce.

scholarly journals Chest CT changes in COVID-19 patients with hypertension comorbidities

2020 ◽  
Author(s):  
Wei Li ◽  
Wenjun Yu ◽  
Jianwei Liao ◽  
Yijie Fang ◽  
Lin Yao ◽  
...  
Keyword(s):  
Global Health ◽  
Clinical Features ◽  
Clinical Data ◽  
Clinical Characteristics ◽  
Ground Glass Opacity ◽  
Chest Ct ◽  
Ground Glass ◽  
Rt Pcr ◽  
Relationship Of ◽  
Pcr Test

Abstract AIMTo summarize the chest CT and clinical features of COVID-19 pneumonia patients with hypertension comorbidities.METHODSThe initial chest CT imaging and clinical data of 15 confirmed COVID-19 patients with hypertension comorbidities treated in our hospital were analyzed retrospectively from January 1, 2019 to February 14, 2020. The chest CT images and clinical data were reviewed and their relationship of the disease was analyzed.RESULTSTotally 15 COVID-19 patients diagnosed with hypertension comorbidities were included. In terms of clinical characteristics, 14/15 (93.3%) of patients had characteristics of clustering onset, and the positive rates of the first RT-PCR test and the initial CT were 80% and 93% respectively. The most frequent CT abnormality observed was ground glass opacity (GGO) (13/15, 86.7%), including patchy/ punctate GGO and large/multiple GGO. Most of the lesions were multiple, and 60% of them involved 4-5 lobes. Most patients present with bilateral CT onset (12,80.0%), and most present with subpleural distribution (10,66.7%). The average CT score is 13.7, and 40% of the patients exceeded 20 points.CONCLUSIONThe common chest CT findings in COVID-19 patients with hypertension comorbidities are GGO, most of which at present with bilateral CT onset and subpleural distribution. CT is indispensable in the diagnosis and evaluation of this global health emergency.

scholarly journals COVID-19 infected patients in a Hemodialysis facility in Ecuador, 2020.

Bionatura ◽  
2021 ◽  
Vol 6 (2) ◽  
pp. 1845-1850
Author(s):  
Mario Hernández ◽  
Emilio Fors ◽  
Fresia Massuht ◽  
Ingrid Figueredo ◽  
Raúl Caballero ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Medical Records ◽  
Clinical Characteristics ◽  
Hemodialysis Patients ◽  
High Rate ◽  
Shortness Of Breath ◽  
The Third ◽  
Before And After ◽  
The Mean ◽  
Epidemiological Characteristics

We retrospectively analyzed the data of 38 hemodialysis patients with COVID-19, including demographic and clinical characteristics were collected from the medical records of patients from Reynadial center from April to June 2020. Of 125 patients from the clinic, 38 (30.4%) were diagnosed with COVID-19. The third part of patients (12) died, the mortality rate was 31%. The mean (±SD) age of the patients was 61±13 years, 57.9% were men. The most common symptoms were shortness of breath and cough; 80% of patients had fever on admission, and more than 90% had hypertension. No significant differences were observed between survivors and non-survivors in demographic and epidemiological characteristics except for gender. We found statistically significant differences between blood pressure and weight before and after the infection by COVID-19. We found a high COVID-19 prevalence in our hemodialysis patients and a high rate of deaths among them, with non-significant statistical differences between survivors and non-survivors of the disease regarding most of the variables studied.

scholarly journals Clinical Features and Management of Oral Nonodontogenic Masses in Children

2020 ◽  
Author(s):  
Hao Zhang ◽  
Qiongqiong Zhou ◽  
Weimin Shen
Keyword(s):  
Clinical Features ◽  
Medical Records ◽  
Pediatric Surgery ◽  
Inflammatory Myofibroblastic Tumor ◽  
Clinical Characteristics ◽  
The Other ◽  
Common Location ◽  
Oral Tumors ◽  
Medical University

Abstract Background: There are numerous clinical reports of oral tumors in children. However, the clinical features and management of oral nonodontogenic masses in children were rare reported. The aim of this article is to present a large series of oral nonodontogenic masses in children, analyzing the clinical characteristics of such masses and reviewing the relevant procedures for treatment.Methods: We conducted an observational retrospective study, reviewing medical records of 171 patients who were treated for oral nonodontogenic masses between 2014 and 2019 at the Department of Pediatric Surgery, Children’s Hospital of Nanjing Medical University. Data collected included age, gender, site, pathologic diagnosis and treatment strategy.Results: All patients were hospitalized in our department. Of the 171 cases, all of them were benign, however, only 1 case diagnosed as inflammatory myofibroblastic tumor showed a malignant process. The most frequent type was hemangioma (63.7%), followed by lymphangioma (16.4%), ranula (7.6%). The most common location of oral masses in the buccal mucosa. The second common location was in tongue. 16 cases of hemangioma were located in two or more sites in cavity. And 29 patients (26.6%) of hemangioma and 11 patients (39.3%) lymphangioma of were found other extraoral lesions. With regard to some cases of hemangioma, the other patients commonly undergone surgical resections or sclerotherapy. The follow-up period ranged from 1 to 5 years. The recurrence rate of hemangioma and lymphangioma were 8.3%, 17.9%, respectively.Conclusion: Most of oral nonodontogenic masses are benign, few oral masses are malignant or mimic a malignant process. Surgical resections are the most common treatment with excellent success.

scholarly journals Comparison of Clinical Features in Octogenarian and Non-octogenarian Adults with Severe COVID-19 Pneumonia

2020 ◽  
Author(s):  
Chang Shu ◽  
Xianling Liu ◽  
Bilian Yu ◽  
Lizhen Yang ◽  
Hong Zhang ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Clinical Features ◽  
Clinical Characteristics ◽  
World Wide ◽  
Chest Ct ◽  
Adult Patients ◽  
Ct Image ◽  
Aged People ◽  
Small Cohort ◽  
Hospital Stay Duration

Abstract Background: Aged people is more susceptible and vulnerable to COVID-19 pneumonia. As the “super-elderly” group, octogenarian COVID-19 patients is not rare in current world-wide common healthy event.Object: To describe clinical features in octogenarian with severe COVID-19. And try to find out the differences with other non-octogenarian adult patients.Materials and Methods: We studied a small cohort of octogenarian COVID-19 patients at a hospital in Wuhan from 10 February to 15 March. We recorded interested clinical data including chest CT in the octogenarian patients. In order to know the differences of clinical characteristics between octogenarian and other adult patients, we included the number of non-octogenarian patients cohort as ratio of 1:3.Result: For octogenarian patients, the age is 83.33±3.08 and 4 are female (4/6,66.7%). For non-octogenarian patients, the age is 60.72±8.28 years and 5 are female(5/18, 27.8%). and 59% were men. Compared non-octogenarian patients, octogenarian patients’ hospital stay duration is significantly longer (p=0.0052*). WBC is obvious elevated in octogenarian(p=0.0494*). BUN (p=0.0377*) and Cr (p=0.0112*) is with obvious differences between two group patients. No obvious differences in CT findings between two groups.Conclusion: The severe COVID-19 pneumonia octogenarian may have more chance to combined with bacterial infection. Octogenarian has worse baseline kidney function than non-octogenarian. In individual cases, the broader lesion and more lesion types may be found in octogenarian CT image.

Ketamine Treatment in Depression: A Systematic Review of Clinical Characteristics Predicting Symptom Improvement

2020 ◽  
Vol 20 (15) ◽  
pp. 1398-1414 ◽  
Author(s):  
Darby J.E. Lowe ◽  
Daniel J. Müller ◽  
Tony P. George
Keyword(s):  
Clinical Features ◽  
Clinical Characteristics ◽  
Bipolar Depression ◽  
Antidepressant Effect ◽  
Future Research ◽  
Symptom Improvement ◽  
Randomized Controlled ◽  
Treatment Of Depression ◽  
Future Direction

Ketamine has been shown to be efficacious for the treatment of depression, specifically among individuals who do not respond to first-line treatments. There is still, however, a lack of clarity surrounding the clinical features and response periods across samples that respond to ketamine. This paper systematically reviews published randomized controlled trials that investigate ketamine as an antidepressant intervention in both unipolar and bipolar depression to determine the specific clinical features of the samples across different efficacy periods. Moreover, similarities and differences in clinical characteristics associated with acute versus longer-term drug response are discussed. Similarities across all samples suggest that the population that responds to ketamine’s antidepressant effect has experienced chronic, long-term depression, approaching ketamine treatment as a “last resort”. Moreover, differences between these groups suggest future research to investigate the potential of stronger efficacy towards depression in the context of bipolar disorder compared to major depression, and in participants who undergo antidepressant washout before ketamine administration. From these findings, suggestions for the future direction of ketamine research for depression are formed.

Acute Colonic Diverticulitis: Diagnostic Evidence, Demographic and Clinical Features in ree Practice Settings

2014 ◽  
Vol 23 (4) ◽  
pp. 379-386 ◽  
Author(s):  
Rajan Iyer ◽  
George F. Longstreth ◽  
Li-Hao Chu ◽  
Wansu Chen ◽  
Linnette Yen ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Emergency Department ◽  
Clinical Features ◽  
Clinical Characteristics ◽  
Past History ◽  
Colonic Diverticulitis ◽  
Co Morbidity ◽  
Objective Evidence ◽  
Multiple Variables ◽  
Acute Colonic Diverticulitis

Background & Aims: Diverticulitis is often diagnosed in outpatients, yet little evidence exists on diagnostic evidence and demographic/clinical features in various practice settings. We assessed variation in clinical characteristics and diagnostic evidence in inpatients, outpatients, and emergency department cases and effects of demographic and clinical variables on presentation features.Methods: In a retrospective cohort study of 1749 patients in an integrated health care system, we compared presenting features and computed tomography findings by practice setting and assessed independent effects of demographic and clinical factors on presenting features.Results: Inpatients were older and more often underweight/normal weight and lacked a diverticulitis past history and had more comorbidities than other patients. Outpatients were most often Hispanic/Latino. The classical triad (abdominal pain, fever, leukocytosis) occurred in 78 (38.6%) inpatients, 29 (5.2%) outpatients and 34 (10.7%) emergency department cases. Computed tomography was performed on 196 (94.4%) inpatients, 110 (9.2%) outpatients and 296 (87.6%) emergency department cases and was diagnostic in 153 (78.6%) inpatients, 62 (56.4%) outpatients and 243 (82.1%) emergency department cases. Multiple variables affected presenting features. Notably, female sex had lower odds for the presence of the triad features (odds ratio [95% CI], 0.65 [0.45-0.94], P<0.05) and increased odds of vomiting (1.78 [1.26-2.53], P<0.01). Patients in age group 56 to 65 and 66 or older had decreased odds of fever (0.67 [0.46-0.98], P<0.05) and 0.46 [0.26-0.81], P<0.01), respectively, while ≥1 co-morbidity increased the odds of observing the triad (1.88 [1.26-2.81], P<0.01).Conclusion: There was little objective evidence for physician-diagnosed diverticulitis in most outpatients. Demographic and clinical characteristics vary among settings and independently affect presenting features.Abbreviations: AD: acute colonic diverticulitis; BMI: body mass index; CT: computed tomography; ED: emergency department; IBS: irritable bowel syndrome; ICD-9-CM: International Classification of Diseases, 9th Revision, Clinical Modification; IP: inpatient; KPSC: Kaiser Permanente Southern California; OP: outpatient.

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