scholarly journals Rotavirus gastroenteritis hospitalizations in provinces with different vaccination coverage rates in Spain, 2013–2018

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
J. Ruiz-Contreras ◽  
S. Alfayate-Miguelez ◽  
B. Carazo-Gallego ◽  
E. Onís ◽  
L. Díaz-Munilla ◽  
...  

Abstract Background Rotavirus (RV) vaccines are available in Spain since 2006 but are not included in the National Immunization Program. RV vaccination has reached an intermediate vaccination coverage rate (VCR) but with substantial differences between provinces. The aim of this study was to assess the ratio of RV gastroenteritis (RVGE) admissions to all-cause hospitalizations in children under 5 years of age in areas with different VCR. Methods Observational, multicenter, cross-sectional, medical record-based study. All children admitted to the study hospitals with a RVGE confirmed diagnosis during a 5-year period were selected. The annual ratio of RVGE to the total number of all-cause hospitalizations in children < 5 years of age were calculated. The proportion of RVGE hospitalizations were compared in areas with low (< 30%), intermediate (31–59%) and high (> 60%) VCR. Results From June 2013 to May 2018, data from 1731 RVGE hospitalizations (16.47% of which were nosocomial) were collected from the 12 study hospitals. RVGE hospital admissions accounted for 2.82% (95 CI 2.72–3.00) and 43.84% (95% CI 40.53–47.21) of all-cause and Acute Gastroenteritis (AGE) hospitalizations in children under 5 years of age, respectively. The likelihood of hospitalization due to RVGE was 56% (IC95%, 51–61%) and 27% (IC95%, 18–35%) lower in areas with high and intermediate VCR, respectively, compared to the low VCR areas. Conclusions RVGE hospitalization ratios are highly dependent on the RV VCR. Increasing VCR in areas with intermediate and low coverage rates would significantly reduce the severe burden of RVGE that requires hospital management in Spain. Clinical trial registration Not applicable

2021 ◽  
Vol 11 (1) ◽  
pp. e5609
Author(s):  
Lidiane Assunção de Vasconcelos ◽  
Emmily Lima Borges ◽  
Daniel Nascimento Souza ◽  
José Natanael Gama dos Santos ◽  
Hilton José Vaz

O Sarampo é uma doença infectocontagiosa com grande importância clínica, sendo a vacinação a forma mais eficaz de prevenção e é assegurada, no Brasil, pelo Programa Nacional de Imunizações (PNI). Contudo, nos últimos anos, houve reemergência de casos de sarampo. Nesse contexto, o trabalho em questão visa analisar a cobertura vacinal contra sarampo, no Pará, no período de 2010 a 2019, e relacionar com o ressurgimento de casos da doença no estado. Trata-se de um estudo observacional do tipo transversal realizado com dados obtidos por meio do Sistema de Informação do Programa Nacional de Imunizações (SI-PNI) e de Boletins Epidemiológicos publicados pelo Ministério da Saúde (MS). Observou-se que as maiores taxas de cobertura vacinal, no Pará, ocorreram nos anos de 2010 (110,95%) a 2014 (115,73%); houve o decréscimo para 69,29%, em 2015 e, até 2019, não se alcançou a meta preconizada pelo MS de 95% de cobertura. Nesse contexto, foram confirmados 41 casos de sarampo no Estado, tornando-o o 6° estado com maior número de casos confirmados dentre os estados analisados. Desta forma, apontam-se fatores que associam o surgimento de casos novos com a diminuição da cobertura, tal qual a hesitação vacinal, alertando que o programa de vacinação deve ser fortalecido para que doenças não retornem ao meio social. ABSTRACTMeasles is an infectious disease of great clinical significance, being vaccination the most effective form of prevention, ensured by the National Immunization Program (Programa Nacional de Imunização – PNI), in Brazil. However, in recent years, there has been reemergence of measles cases. In this context, this study aims to analyze measles vaccination coverage in the State of Pará from 2010 to 2019 and relate it to the resurgence of disease cases in the state. This is an observational cross-sectional study conducted with data obtained through the Information System of the National Immunization Program (Sistema de Informação do Programa Nacional de Imunizações – SI-PNI) and Epidemiological Bulletins published by the Ministry of Health (Ministério da Saúde – MS). It was observed that highest vaccination coverage rates occurred in the years 2010 (110.95%) to 2014 (115.73%), there was a decrease to 69.29%, in 2015, and until 2019, it did not reach the goal recommended by the MS, which is 95% coverage. In this context, 41 measles cases were confirmed in state, making it the 6th state with the highest number of confirmed cases among the analyzed states. Thus, factors that link the emergence of new cases with decreased coverage are pointed out, such as vaccination hesitation, showing that strengthening the vaccination program is necessary, so that diseases do not return to the social environment.Keywords: Measles; Vaccination coverage; Immunization. RESUMENEl sarampión es una enfermedad infecciosa de gran importancia clínica, siendo la vacunación una forma de prevención más eficaz y asegurada, en Brasil, por el Programa Nacional de Inmunizaciones (PNI). Sin embargo, en los últimos años ha habido un resurgimiento de casos de sarampión. En este contexto, el trabajo en cuestión tiene como objetivo analizar la cobertura de vacunación contra el sarampión, en Pará, en el período de 2010 a 2019, y relacionarla con el resurgimiento de casos de la enfermedad en el estado. Se trata de un estudio observacional, transversal realizado con datos recolectados a través del Sistema de Información del Programa Nacional de Inmunizaciones (SI-PNI) y de los Boletines Epidemiológicos publicados por el Ministerio de Salud (MS). Se observó que las mayores tasas de cobertura de vacunación, en Pará, ocurrieron en los años 2010 (110,95%) a 2014 (115,73%); hubo una disminución a 69,29% en 2015 y, hasta 2019, no se alcanzó la meta recomendada por el Ministerio de Salud de cobertura del 95%. En este contexto, se confirmaron 41 casos de sarampión en el estado, lo que lo convierte en el sexto estado con el mayor número de casos confirmados dentro de los estados moldeados. Así, se señalan factores que asocian la aparición de nuevos casos con la disminución de coberturas, como la vacilación vacunal, advirtiendo que se debe fortalecer el programa de vacunación para que las enfermedades no regresen al ámbito social.Palabras clave: Sarampión; Cobertura de vacunación; Inmunización.


2021 ◽  
Vol 14 (11) ◽  
Author(s):  
Mariana Dias de Borba ◽  
Carlos Eduardo da Cunha Nascimento ◽  
Gabriel Mael Sussuarana Silva Lobo ◽  
Lucca Gonçalo de Castro Lima ◽  
Camila Lays Winter ◽  
...  

Brazil has the National Immunization Program for disease prevention that offers nineteen vaccines, yet it is known that vaccination coverage according to age is not always reached. Thus, this study aimed to evaluate the vaccination coverage in the municipality of Sinop, in the Mato Grosso state and in the Brazil for meningococcal C conjugate vaccines and Hepatitis B in the period from 2015 to 2019. Method: This is a descriptive, retrospective and cross-sectional study, with data available in the Information System of the National Immunization Program. Results: Vaccination coverage for mingococcal C in children under one year in Sinop was above the target in 2015 and 2018, Mato Grosso was above only in 2015, for the booster dose only Sinop was above the target in 2016. Coverage for hepatitis B in children under 30 days of life demonstrated that Sinop had coverage above the state of Mato Grosso, which in turn was above Brazil. For children under 1 year old, only in 2016 and 2019 the state presented greater vaccination coverage at the expense of Sinop and Brazil. Conclusion: The results demonstrate that there is hesitation on the part of the population regarding vaccination, being greater in vaccines such as meningococcal C. Strengthening childcare is the key to improving the panorama of vaccine coverage.


2009 ◽  
Vol 124 (5) ◽  
pp. 642-651 ◽  
Author(s):  
Nidhi Jain ◽  
James A. Singleton ◽  
Margrethe Montgomery ◽  
Benjamin Skalland

Since 1994, the Centers for Disease Control and Prevention has funded the National Immunization Survey (NIS), a large telephone survey used to estimate vaccination coverage of U.S. children aged 19–35 months. The NIS is a two-phase survey that obtains vaccination receipt information from a random-digit-dialed survey, designed to identify households with eligible children, followed by a provider record check, which obtains provider-reported vaccination histories for eligible children. In 2006, the survey was expanded for the first time to include a national sample of adolescents aged 13–17 years, called the NIS-Teen. This article summarizes the methodology used in the NIS-Teen. In 2008, the NIS-Teen was expanded to collect state-specific and national-level data to determine vaccination coverage estimates. This survey provides valuable information to guide immunization programs for adolescents.


Author(s):  
Dwi Endarti ◽  
Irfan Ahmad ◽  
Tri Murti Andayani

Hepatitis A is a viral disease with a high potential for morbidity and mortality which is also the second highest incidence in Indonesia after hepatitis B. The purpose of this research is to measure knowledge of Indonesian community about hepatitis A disease and vaccine and to analyze the factors related to knowledge. This study used an observational survey research design applying a cross-sectional multi-center approach. The number of sample was 500 respondents located in 5 provinces in Indonesia, namely DIY, Lampung, West Java, North Kalimantan, and Central Sulawesi. Data collection was carried out using a questionnaire that was modified from the questionnaire in a similar study before. The results showed that the mean of knowledge score obtained was 75.2% ± 12.2% with a median of 76.9%. There are 2 items of knowledge that were lack understood by respondents, namely treatment of hepatitis A that cannot be treated with antibiotics and immunizations and hepatitis A is not included yet in the national immunization program in Indonesia. Statistical analysis using Mann-Whitney test showed that there were significant differences score of knowledge between groups on the characteristics of the number of dependents (p=0,000), experience of hearing a disease (p=0,000), experience of hearing a vaccine (p=0,000) and the experience of the child being vaccinated (p=0,000). It is recommended that the government conducts education programs for the community of Indonesia to improve knowledge related to hepatitis A diseases and the benefits of using hepatitis Avaccine.


Author(s):  
Irfan Ahmad ◽  
Dwi Endarti ◽  
Tri Murti Andayani

Hepatitis A is a viral disease with a high potential for morbidity and mortality. It is also the second highest viral disease in Indonesia after hepatitis B. Community’s knowledge regarding Hepatitis A disease dan vaccine is required to support such program for eradication of Hepatitis A. The aims of this study was to measure the knowledge of Indonesian community about hepatitis A disease and its vaccine indicated from knowledge score of correct answer towards questionnaire, as well as to analyze the factors that can influence it indicated from difference of mean of knowledge scores among groups of respondents characteristics. This study used an observational survey research design applying a cross-sectional multi-center approach. The number of sample was 500 respondents located in 5 provinces in Indonesia, namely DIY, Lampung, West Java, Central Kalimantan, and Central Sulawesi. Data collection was carried out using a questionnaire that was modified from the questionnaire in a similar previous study. The results showed that public knowledge related to diseases and hepatitis A vaccine in Indonesia was considered sufficient with the mean score obtained was 75.2% ± 12.2%. Statistical analysis using Mann-Whitney test showed that there were significant differences in score of knowledge between groups on the characteristics of experience of hearing a disease (p=0,000), experience of hearing a vaccine (p=0,000) and the experience of the child being vaccinated (p=0,000). There are 2 items of knowledge that werelack understood by respondents, namely treatment of hepatitis A that cannot be treated with antibiotics and immunizations and hepatitis A is not included yet in the national immunization program in Indonesia. It is concluded that community knowledge regarding hepatitis A disease and vaccine was fair (mean knowledge score between 65 – 80%). However, the government still needs to conduct educational programs for the Indonesian community about disease prevention through the vaccination process and provide counseling about the types of vaccines that are not included in the national health insurance program in Indonesia.


2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Satoko Ohfuji ◽  
Akira Takagi ◽  
Takashi Nakano ◽  
Hideaki Kumihashi ◽  
Munehide Kano ◽  
...  

Abstract Background In Japan, mumps vaccination coverage is low, since it is a voluntary vaccination. In this situation, the number of mumps cases as reported by pediatric sentinel hospitals suggests the occurrence of periodical mumps outbreaks. Methods To examine the annual incidences of mumps and mumps-related complications, we analyzed data from the health insurance reimbursement database for subscribers aged 0-64 years between 2005 and 2017. Cases with mumps and mumps-related complications including meningitis, orchitis, deafness, were extracted according to ICD-10 codes entered into the disease section for health insurance reimbursement. Results During the 13 year period, 68,307 of 5,209,660 subjects were reimbursed for mumps, with an incidence of 325 per 100,000 person-years (95% confidence interval (CI): 323-328). Among the 68,307 mumps cases, 787 were reimbursed for mumps-related complications, with an incidence of 11.5 per 1,000 mumps cases (95% CI: 10.7-12.4). Incidence of mumps-related complications (per 1,000 mumps cases) was highest for orchitis (6.6), followed by meningitis (5.8), deafness (1.3), pancreatitis (0.5), and encephalitis (0.3). Mumps incidence was highest among children aged 0-5 years, while incidence of mumps-related complications was highest among adults aged 26-35 years. Conclusions In Japan, the disease burden of mumps remains high among adults, as well as children. Key messages To reduce the disease burden of mumps among all ages in Japan, immunization in childhood is required. A national immunization program for children would result in high vaccination coverage and lower disease burden.


2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
A Tognetto ◽  
A Abbondanzieri ◽  
G Cerone ◽  
M Di Pumpo ◽  
A Nardi ◽  
...  

Abstract Background Seasonal influenza vaccination (SIV) of health care workers (HCWs) is well recognized as a public health measure that can protect both HCWs from infection and patients from the risk of influenza complications. Nevertheless, vaccination coverage rates among this specific population result generally lower than the recommended target. With our study, we aimed to describe the activities and the outcomes of four different SIV campaigns targeted at HCWs and organized during the season 2018/2019 in four hospitals in Rome. Methods A cross-sectional study involving four teaching hospitals was performed. The collected data were synthetized into a set of descriptors and indicators, validated through a previous study that had involved the same Centers. Results The Medical Directorates, in collaboration with the University Hygiene and Public Health Units of the four hospitals organized different strategies: Hospital 1, 3 and 4 realized educational courses for HCWs and actively promoted the campaigns through e-mail invitations to all HCWs. As for the access to vaccination, all the hospitals provided a dedicated unit for SIV; Hospital 1 and Hospital 4 organized also on-site vaccination sessions in the hospital wards, that required a large number of staff. The vaccination coverage rates resulted: 22.37% in Hospital 1, 18.10% in Hospital 4, 9.28% in Hospital 2 and 8,51% in Hospital 3. Conclusions Our results demonstrate that multi-activity campaigns, involving education, promotion and easy access to vaccination constitute an effective approach to reinforce the value of SIV. Our findings suggest that on-site vaccination may play a key role in determining a higher vaccination coverage. Key messages Multi-activity vaccination campaigns, involving education, promotion and easy access to vaccination constitute an effective approach to reinforce the value of seasonal influenza vaccination for HCWs. On-site vaccination may play a key role in determining a higher vaccination coverage.


Vaccines ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 535 ◽  
Author(s):  
Mauro Amato ◽  
José Pablo Werba ◽  
Beatrice Frigerio ◽  
Daniela Coggi ◽  
Daniela Sansaro ◽  
...  

Background: The lack of specific vaccines or drugs against coronavirus disease 2019 (COVID-19) warrants studies focusing on alternative clinical approaches to reduce the spread of this pandemic disease. In this study, we investigated whether anti-influenza vaccination plays a role in minimizing the diffusion of COVID-19 in the Italian population aged 65 and over. Methods: Four COVID-19 outcomes were used: severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence, hospitalizations for COVID-19 symptoms, admissions to intensive care units for reasons related to SARS-CoV-2, and deaths attributable to COVID-19. Results: At univariate analyses, the influenza vaccination coverage rates correlated negatively with all COVID-19 outcomes (Beta ranging from −134 to −0.61; all p < 0.01). At multivariable analyses, influenza vaccination coverage rates correlated independently with SARS-CoV-2 seroprevalence (Beta (95% C.I.): −130 (−198, −62); p = 0.001), hospitalizations for COVID-19 symptoms (Beta (95% C.I.): −4.16 (−6.27, −2.05); p = 0.001), admission to intensive care units for reasons related to SARS-CoV-2 (Beta (95% C.I.): −0.58 (−1.05, −0.12); p = 0.017), and number of deaths attributable to COVID-19 (Beta (95% C.I.): −3.29 (−5.66, −0.93); p = 0.010). The R2 observed in the unadjusted analysis increased from 82% to 159% for all the considered outcomes after multivariable analyses. Conclusions: In the Italian population, the coverage rate of the influenza vaccination in people aged 65 and over is associated with a reduced spread and a less severe clinical expression of COVID-19. This finding warrants ad hoc studies to investigate the role of influenza vaccination in preventing the spread of COVID-19.


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