scholarly journals Effectiveness of joint 3 + 1 malaria strategy along China–Myanmar cross border areas

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zu-rui Lin ◽  
Shi-gang Li ◽  
Xiao-dong Sun ◽  
Xiang-rui Guo ◽  
Zhi Zheng ◽  
...  
Keyword(s):  
Malaria Elimination ◽  
Prevalence Rate ◽  
Parasite Prevalence ◽  
Pilot Project ◽  
Vector Surveillance ◽  
Trap Night ◽  
Cross Border ◽  
Border Malaria ◽  
Significant Difference ◽  
Border Areas

Abstract Background Cross-border malaria in Laiza City of Myanmar seriously affected Yingjiang County of China and compromised reaching the goal of malaria elimination by 2020. Since 2017, a pilot project on 3 + 1 strategy of joint cross-border malaria prevention and control was carried out for building a malaria buffer in these border areas. Here, 3 were the three preventive lines in China where different focalized approaches of malaria elimination were applied and + 1 was a defined border area in Myanmar where the integrated measures of malaria control were adopted. Methods A 5-year retrospective analysis (2015 to 2019) was conducted that included case detection, parasite prevalence and vector surveillance. Descriptive statistics was used and the incidence or rates were compared. The annual parasite incidence and the parasite prevalence rate in + 1 area of Myanmar, the annual importation rate in Yingjiang County of China and the density of An. minimus were statistically significant indictors to assess the effectiveness of the 3 + 1 strategy. Results In + 1 area of Myanmar from 2015 to 2019, the averaged annual parasite incidence was (59.11 ± 40.73)/1000 and Plasmodium vivax accounted for 96.27% of the total confirmed cases. After the pilot project, the annual parasite incidence dropped 89% from 104.77/1000 in 2016 to 12.18/1000 in 2019, the microscopic parasite prevalence rate dropped 100% from 0.34% in 2017 to zero in 2019 and the averaged density of An. Minimus per trap-night dropped 93% from 1.92 in June to 0.13 in September. The submicroscopic parasite prevalence rate increased from 1.15% in 2017 to 1.66% in 2019 without significant difference between the two surveys (P = 0.084). In Yingjiang County of China, neither indigenous nor introduced case was reported and 100% cases were imported from Myanmar since 2017. The averaged annual importation rate from 2015 to 2019 was (0.47 ± 0.15)/1000. After the pilot project, the annual importation rate dropped from 0.59/1000 in 2016 to 0.28/1000 in 2019 with an overall reduction of 53% in the whole county. The reduction was 67% (57.63/1000 to 18.01/1000) in the first preventive line, 52% (0.20/1000 to 0.10/1000) in the second preventive line and 36% (0.32/1000 to 0.22/1000) in the third preventive line. The averaged density of An. Minimus per trap-night in the first preventive line dropped 94% from 2.55 in June to 0.14 in September, without significant difference from that of + 1 area of Myanmar (Z value = − 1.18, P value = 0.24). Conclusion The pilot project on 3 + 1 strategy has been significantly effective in the study areas and a buffer zone of border malaria was successfully established between Laiza City of Myanmar and Yingjiang County of China.

scholarly journals Effectiveness of Joint 3+1 Malaria Strategy Along China-Myanmar Cross Border Areas

2020 ◽  
Author(s):  
Zu-rui Lin ◽  
Shi-gang Li ◽  
Xiao-dong Sun ◽  
Xiang-rui Guo ◽  
Zhi Zheng ◽  
...  
Keyword(s):  
Plasmodium Vivax ◽  
Prevalence Rate ◽  
Indoor Residual Spraying ◽  
Parasite Prevalence ◽  
Pilot Project ◽  
Vector Surveillance ◽  
Buffer Area ◽  
Cross Border ◽  
Border Malaria ◽  
Significant Difference

Abstract Background: Cross-border malaria in Laiza City of Myanmar seriously compromised the achieving goal of malaria elimination in Yingjiang County of China. A pilot project on 3+1 strategy of joint cross-border malaria prevention and control was carried out in building border malaria buffer area in the both sides since 2017; Here, 3 was the three preventive lines in Yingjiang County to strengthen targeted measures of elimination malaria in China and +1 was a defined border area in Laiza City to adopt the integrated measures of malaria control in Myanmar. Methods: A retrospective analysis from 2015 to 2019 was conducted and the descriptive statistics was used to analyze and compare the data of malaria case detection, parasite prevalence and vector surveillance. Results: In +1 area of Myanmar from 2015 to 2019, the average of annual parasite incidence was (59.11±40.73) / 1000 and plasmodium vivax accounted for 96.27 % of total confirmed cases. After the pilot project, the annual parasite incidence, microscopic parasite prevalence rate and density of An. Minimus reduced by 89%,100% and 93.93% respectively, but the submicroscopic parasite prevalence rate was no significant difference between the two surveys (p =0.084). In Yingjiang County of China, neither indigenous nor introduced case was reported and 100% cases were imported from Myanmar since 2017. The average of annual importation rate from 2015 to 2019 was (0.47±0.15)/1000. After the pilot project, it reduced by 53% of whole county, 67% of the first preventive line, 52% of the second preventive line and 36% of the third preventive line respectively. Conclusion: The pilot project on 3+1 strategy has made remarkable effectiveness and a buffer area of border malaria was successfully established between Laiza City of Myanmar and Yingjiang County of China. The combined use and expanded coverage of indoor residual spraying and long-lasting insecticidal nets (LLINs) was more effective than only use of LLINs in reducing the transmission of plasmodium vivax caused by An. Minimus. It is necessary to adopt submicroscopic infection interventions to eliminate potential sources of infection in Laiza City of Myanmar.

scholarly journals Effectiveness of Joint 3+1 Malaria Strategy Along China-Myanmar Cross Border Areas

2020 ◽  
Author(s):  
Zu-rui Lin ◽  
Shi-gang Li ◽  
Xiao-dong Sun ◽  
Xiang-rui Guo ◽  
Zhi Zheng ◽  
...  
Keyword(s):  
Plasmodium Vivax ◽  
Prevalence Rate ◽  
Indoor Residual Spraying ◽  
Parasite Prevalence ◽  
Pilot Project ◽  
P Value ◽  
Buffer Area ◽  
Cross Border ◽  
Border Malaria ◽  
Significant Difference

Abstract Background: Cross-border malaria in Laiza City of Myanmar seriously affected Yingjiang County of China and compromised the national malaria elimination goal. A pilot project on 3+1 strategy of joint cross-border malaria prevention and control was carried out in building border malaria buffer area in the both sides since 2017; Here, 3 was the three preventive lines in Yingjiang County to strengthen targeted measures of elimination malaria in China and +1 was a defined border area in Laiza City to adopt the integrated measures of malaria control in Myanmar.Methods: A retrospective analysis from 2015 to 2019 was conducted that included case detection, parasite prevalence and vector surveillance. Descriptive statistics was used and the incidence or rates were compared. The annual parasite incidence in +1 area of Myanmar, the annual importation rate in Yingjiang County of China and the density of An.Minimus were statistically significant indictors to assess the effect of the joint interventions.Results: In +1 area of Myanmar from 2015 to 2019, the average of annual parasite incidence was (59.11±40.73) / 1000 and plasmodium vivax accounted for 96.27 % of total confirmed cases. After the pilot project, the annual parasite incidence, microscopic parasite prevalence rate and density of An. Minimus reduced by 89%,100% and 93.93% respectively, but the submicroscopic parasite prevalence rate was no significant difference between the two surveys (p =0.084). In Yingjiang County of China, neither indigenous nor introduced case was reported and 100% cases were imported from Myanmar since 2017. The average of annual importation rate from 2015 to 2019 was (0.47±0.15)/1000. After the pilot project, it reduced by 53% of whole county, 67% of the first preventive line, 52% of the second preventive line and 36% of the third preventive line respectively. The density of An. Minimus in the first preventive line reduced by 94.51% and did not have significant difference between that of+1 area of Myanmar (Z value=-1.18，p value=0.24). Conclusion: The pilot project on 3+1 strategy has made remarkable effectiveness and a buffer area of border malaria was successfully established between Laiza City of Myanmar and Yingjiang County of China. The combined use and expanded coverage of indoor residual spraying and long-lasting insecticidal nets (LLINs) was more effective than only use of LLINs in reducing the transmission of plasmodium vivax caused by An. Minimus. It is necessary to adopt submicroscopic infection interventions to eliminate potential sources of infection in Laiza City of Myanmar.

scholarly journals The 2019 Isdell:Flowers Cross Border Malaria Initiative Round Table: community engagement in the context of malaria elimination

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Alexandra Gordon ◽  
Rebecca J. Vander Meulen ◽  
Alysse Maglior
Keyword(s):  
Private Sector ◽  
Community Engagement ◽  
Malaria Elimination ◽  
Round Table ◽  
Government Officials ◽  
Community Members ◽  
Cross Border ◽  
Border Malaria ◽  
Effective Community

AbstractGovernment officials, representatives from malaria endemic communities, and nonprofit, academic, and private sector partners convened at the 2019 Isdell:Flowers Cross Border Malaria Initiative Round Table in Livingstone, Zambia from February 28–March 1, 2019 to discuss the necessity of community engagement and the involvement of those directly affected by malaria in malaria elimination efforts. Participants shared practical examples and principles of successful community engagement over the course of the Round Table. Three core principles of effective community engagement emerged: (1) there is no “one size fits all” community engagement strategy, (2) community engagement must be a bidirectional activity, and (3) community members must be at the heart of malaria elimination efforts.

scholarly journals Cross-Border Malaria: A Major Obstacle for Malaria Elimination

2015 ◽  
pp. 79-107 ◽  
Author(s):  
Kinley Wangdi ◽  
Michelle L. Gatton ◽  
Gerard C. Kelly ◽  
Archie CA. Clements
Keyword(s):  
Malaria Elimination ◽  
Major Obstacle ◽  
Cross Border ◽  
Border Malaria

Speech Methodologies in Cleft Palate Assessment: A Pilot Project to Compare Two Phonetically Different Sentence Sets

2013 ◽  
Vol 20 (1) ◽  
pp. 49-72
Author(s):  
Jennie Smith ◽  
Tim Pring ◽  
Debbie Sell
Keyword(s):  
Cleft Palate ◽  
Pilot Project ◽  
Wilcoxon Test ◽  
Consecutive Series ◽  
Video Recordings ◽  
Significant Difference ◽  
The Difference ◽  
Audio Video ◽  
Age Range ◽  
The Impact

Objective: To investigate the impact of the phonetic content of two sentence sets on speech outcomes, specifically the effects of nasal phonemes. Method: Audio-video recordings of a consecutive series of 15 participants (age range 4–22 years), with cleft palate (syndromic or non-syndromic), with and without velopharyngeal dysfunction were taken. Participants repeated Sentence Set 1 (with nasals across sentences) and Sentence Set 2 (without nasals except the three nasal target sentences) during a routine speech recording. Two experienced Specialist Speech and Language Therapists, blinded to the study’s purpose, analyzed participants’ speech using the Cleft Audit Protocol for Speech-Augmented (CAPS-A). On day 1, recordings included Sentence Set 1. On day 2, 23 days later, recordings included Sentence Set 2. Main results: The difference between Sentence Set 1 and Sentence Set 2 ‘total scores’ (sum of scores on all CAPS-A parameters) was significant. The Pearson Product Moment showed high correlation. A Wilcoxon test revealed a significant difference between Sets 1 and 2 on the hypernasality parameter, and this alone accounted for the significant difference in total scores. Conclusion: The inclusion or exclusion of nasal consonants in the sentence set significantly affected perceptual ratings of hypernasality but none of the other CAPS-A parameters, highlighting the need for further investigation into perceptual nasality ratings.

scholarly journals Gastrointestinal Parasitism in Miranda Donkeys: Epidemiology and Selective Control of Strongyles Infection in the Northeast of Portugal

Animals ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 155
Author(s):  
Sérgio Ramalho Sousa ◽  
Sofia Anastácio ◽  
Miguel Nóvoa ◽  
Adolfo Paz-Silva ◽  
Luís Manuel Madeira de Carvalho
Keyword(s):  
Prevalence Rate ◽  
Negative Binomial ◽  
Control Program ◽  
Parasite Prevalence ◽  
Gastrointestinal Parasites ◽  
Selective Treatment ◽  
Control Approach ◽  
Native Breed ◽  
Parasite Biodiversity ◽  
Gastrointestinal Parasitism

In Portugal, equine parasitism in pasture animals is characterized by high parasitic burden and high helminthic biodiversity; both factors are potentially pathogenic for their hosts. The decrease in the number of donkeys over the last years in Portugal, their importance in rural lowland and mountain ecosystems and pastures and the scarce information regarding their parasitism led to this research, which aimed to evaluate the parasitological status of a Miranda donkey breed population, a native breed mainly located in the northeast of Portugal. This study provides better knowledge of their gastrointestinal parasitism, particularly strongyles, and the assessment of a targeted selective treatment (TST) as an alternative control approach of their parasitism. A longitudinal observational study was developed during a period of five years in a population of 62 Miranda donkeys. At first, strategic deworming of these animals was performed every semester, but this was progressively replaced by a TST approach according to the levels of Eggs per Gram (EPG). This new deworming strategy was conducted in association with a regular parasitological monitoring of the animals every three months, being dewormed with ivermectin when egg shedding was higher than 500 EPG. Over the study period, a decrease of the annual prevalence rate of infection by gastrointestinal strongyles was observed, from 35.5% to 19.4%, as well as a negative binomial distribution of parasitic strongyles in donkeys submitted to selective anthelminthic control. The prevalence rate of infection was higher in females (39.5%), in individuals under four years (46.7%) and in those presenting a lower body condition (40.8%). The egg output was higher in animals younger than four years (589.3 EPG) than in those older than 10 years (533.6 EPG) (p < 0.05). However, no differences were observed according to sex during the study period. Results from this study allowed to note the influence of swampy pastures and of the weather changes in the epidemiology of strongylosis in Miranda donkeys. Moreover, it was possible to establish the annual epidemiological curve of strongyle egg shedding, with June being the month with the highest EPG, December having the lowest EPG and March and September showing intermediate numbers. Overall, a lower biodiversity of gastrointestinal parasites was observed. Cyathostomum sensu lato was the most prevalent genus and Strongylus vulgaris was the most observed large strongyle of the Strongylidae family. Trichostrongylus axei and Parascaris sp. were other nematodes with a minor frequency. The higher prevalence of strongyles at the beginning of the study showed a progressive decrease throughout the research period, and also for parasite biodiversity. Therefore, a targeted selective treatment seems to be a rational anthelminthic control approach in Miranda donkey strongyle infection and in other gastrointestinal parasites, since it reduces the antiparasitic treatments, the parasite’ prevalence and the EPG level. However, a loss of parasite biodiversity was noted at the end of the study period, as Cyathostominae were the only isolated strongyles. This can be a challenging situation in the long run, taking the ability of these nematodes to adapt easily to any deworming program, meaning that fecal EPG monitoring should be kept as a rule to a rational parasite control program.

scholarly journals Experiencias biográficas de trabajadoras en la industria de exportación en el norte de México y Marruecos

2018 ◽  
pp. 23
Author(s):  
Rosa M. Soriano Miras ◽  
Kathryn Kopinak ◽  
Antonio Trinidad Requena
Keyword(s):  
Work Experience ◽  
Economic Globalization ◽  
Export Industry ◽  
Expressive Function ◽  
Cross Border ◽  
Biographical Approach ◽  
Border Areas ◽  
The Cross ◽  
Las Mujeres ◽  
And Migration

El presente artículo reflexiona sobre cómo la globalización económicaafecta a la vida de las mujeres que trabajan en la industria de exportaciónen espacios fronterizos marcados por la porosidad de dicha frontera. Hemos queridointerrogarnos acerca de cómo lo macro afecta a lo micro, coadyuvando a lageneración de espacios glolocales, donde la vivencia transfronteriza y la migración(interna o internacional) adquiere relevancia. Para ello se han escogido dosrelatos biográficos (para cada caso estudiado) que nos ayudan a ejemplificar dichasvivencias, enfatizando la función expresiva del enfoque biográfico al que se refiereBertaux. Ambos casos se han seleccionado de una investigación más amplia querecoge la vida de ochenta mujeres que cuentan con experiencia laboral en la industriade exportación en la frontera de México con EEUU y la de Marruecos conEspaña.This article reflects on how economic globalization affects the livesof women working in the export industry in border areas marked by the porosity ofsaid border. We wanted to ask ourselves about how the macro affects the micro,helping to generate glolocal spaces, where the cross-border experience and migration(internal or international) becomes relevant. To this end, two biographicalaccounts have been chosen (for each case studied) that help us to exemplify theseexperiences, emphasizing the expressive function of the biographical approach towhich Bertaux refers. Both cases have been selected from a wider investigationthat includes the lives of more than a hundred and fifty people (eighty women) whohave work experience in the export industry on the border of Mexico with the USand Morocco with Spain.

scholarly journals Parasites and vectors carry no passport: how to fund cross-border and regional efforts to achieve malaria elimination

2012 ◽  
Vol 11 (1) ◽  
Author(s):  
Cara Smith Gueye ◽  
Alexandra Teng ◽  
Kelvin Kinyua ◽  
Frank Wafula ◽  
Roly Gosling ◽  
...  
Keyword(s):  
Malaria Elimination ◽  
Cross Border

scholarly journals Early Detection and Intervention for Patients with Delirium Admitted to the Department of Internal Medicine: Lessons from a Pilot Initiative

2021 ◽  
pp. 134-139
Author(s):  
Ron Oliven ◽  
Meital Rotfeld ◽  
Sharon Gino-Moor ◽  
Elad Schiff ◽  
Majed Odeh ◽  
...  
Keyword(s):  
Internal Medicine ◽  
Early Detection ◽  
Emergency Room ◽  
Early Mobilization ◽  
Pilot Project ◽  
Medical Emergency ◽  
Medical Patients ◽  
Geriatric Unit ◽  
Retrospective Comparison ◽  
Significant Difference

<b><i>Introduction:</i></b> Older patients who arrive to the emergency room with delirium have a worse prognosis than others. Early detection and treatment of this problem has been shown to improve outcome. We have launched a project at our hospital to improve the care of patients who arrive delirious to the medical emergency room. The present article describes lessons that can be learned from this pilot initiative. <b><i>Methods:</i></b> All patients older than 70 years admitted to the department of internal medicine were screened for delirium in the emergency room using the 4AT screening tool. Data of patients with a 4AT score ≥5 (or with incomplete score) were transferred to the geriatric unit of the hospital. On the ward, the presence of delirium was confirmed by a geriatric nurse that validated that the patient could walk with support and ordered mobilization and physiotherapy (M&amp;P). <b><i>Results:</i></b> Over the 2 and a half years (10 quarters) allocated for the pilot project, 1,078 medical patients with delirium were included in this survey. In 59.3%, the diagnosis of delirium could be confirmed only after admission. Due to budgetary constraints, only 54.7% received the allocated specific intervention – early M&amp;P. Since it was decided that randomization was not appropriate for our initiative, we found that patients who received M&amp;P had lower (better) 4AT scores on admission, and lower mortality. No significant difference was found between the patients who received M&amp;P and the others in length of hospitalization and discharge to nursing homes. Retrospective comparison of the two groups did not enable to determine whether M&amp;P was given to the patients for whom it was most effective. <b><i>Conclusions:</i></b> It is often not possible to verify in the emergency room that the cognitive decline is indeed new, that is, is due to delirium, and measures must be taken to verify this point as soon as possible after admission. Due to numerous constraints, the availability of early M&amp;P is often insufficient. Whenever resources are scarce and randomization is avoided, adequate criteria should be found for allocating existing dedicated staff to patients for whom early mobilization is likely to be most beneficial.

scholarly journals The occurrence of Contracaecum sp. larvae (Nematoda : Anisakidae) in the catfishClarias gariepinus (Burchell) from Lake Chivero, Zimbabwe

2004 ◽  
Vol 71 (1) ◽  
Author(s):  
M. Barson
Keyword(s):  
Significant Relationship ◽  
Condition Factor ◽  
Clarias Gariepinus ◽  
Parasite Prevalence ◽  
Body Cavity ◽  
The Body ◽  
Nematode Parasites ◽  
Significant Difference ◽  
Third Stage ◽  
Males And Females

Clarias gariepinus were collected from Lake Chivero, Zimbabwe, and examined for nematode parasites from November 2000 to May 2002. Of the 202 specimens collected, 42.6 % were infected with third-stage larvae of Contracaecum sp. in the body cavity. The intensity of the infection was 1-7 worms per fish (mean intensity = 2.2). Seasonal variation in the prevalence of the parasite was not obvious and there was no significant difference in the prevalence of infection between males and females (c2 = 2.228; P > 0.05). No significant relationship between host size and prevalence was established. There was also no significant relationship between intensity and the body condition factor (r = 0.11; P > 0.05). The low parasite prevalence may have been caused by the disruption of the infection cycle since piscivorous birds, which are the final hosts of the parasite, do not feed on C. gariepinus in Lake Chivero.

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