scholarly journals Comparison of the curative effect and prognosis of stereotactic drainage and conservative treatment for moderate and small basal ganglia haemorrhage

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xin Huang ◽  
Lai Jiang ◽  
Shaojun Chen ◽  
Gang Li ◽  
Wanxi Pan ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Large Scale ◽  
Neurological Function ◽  
Lower Limbs ◽  
Control Group ◽  
Roc Curve Analysis ◽  
Curative Effect ◽  
Nihss Score ◽  
Haematoma Volume ◽  
Experimental Group

Abstract Background Minimally invasive surgery has achieved good results in the treatment of cerebral haemorrhage.However, no large-scale clinical study has demonstrated that surgical treatment of cerebral haemorrhages less than 30 ml can improve the curative effect. Our study explored the efficacy and complication of stereotactic drainage based on the amount of cerebral hemorrhage (15-30 ml) in hypertensive basal ganglia. Method Sixty patients with hypertensive basal ganglia haemorrhages were divided into a control group and an experimental group with 30 patients in each group. Patients in the control group were treated conservatively. In contrast, those in the experimental group received stereotactic drainage, and urokinase was injected into the haematoma cavity after the operation. The haematoma volume at admission and 1, 3, 7 and 30 days after treatment and National Institute of Health stroke scale(NIHSS) score data were recorded. Complications after treatment in the two groups of data were compared and analysed. Result No significant differences in age, sex, time of treatment after onset, admission blood pressure, admission haematoma volume or admission NIHSS score were noted between these two groups (P > 0.05). After treatment, significant differences in haematoma volume were noted between the two groups on the 1st, 3rd, 7th and 30th days after treatment (P < 0.05). The amount of hematoma of patients in the experimental group was significantly reduced compared with that in the control group, and the NIHSS scores were significantly different on the 3rd, 7th and 30th days after treatment. The neurological deficit scores of patients in the experimental group were significantly reduced compared with those in the control group, and the incidence of pulmonary infection and venous thrombosis in the lower limbs of patients in the experimental group were significantly reduced (P < 0.05). ROC curve analysis showed that stereotactic drainage affected the early neurological function of patients with small and medium basal ganglia haemorrhages. Conclusion For patients with small and medium basal ganglia haemorrhages, stereotactic drainage can be used due to the faster drainage speed of haematomas after operation, which is beneficial to the recovery of neurological function and reduce complications.

scholarly journals Early path nursing on neurological function recovery of cerebral infarction

2019 ◽  
Vol 10 (1) ◽  
pp. 160-163
Author(s):  
Ling Chen ◽  
Zhena Han ◽  
Junjie Gu
Keyword(s):  
Cerebral Infarction ◽  
Conventional Treatment ◽  
Neurological Function ◽  
Early Rehabilitation ◽  
Control Group ◽  
P Value ◽  
Treatment Methods ◽  
Rehabilitation Care ◽  
Function Recovery ◽  
Experimental Group

Abstract Purpose to study the application of path type early rehabilitation nursing in the nursing of patients with cerebral infarction and to explore its impact on the recovery of neurological function. Methods Patients with acute cerebral infarction in our hospital were randomly divided into two groups. The control group used conventional treatment methods. The experimental group used path type early rehabilitation care based on conventional treatment methods and observed the curative effect. ResultsThe NIHSS scores in the experimental group were significantly lower than those in the control group, and the P value was less than 0.05, which was statistically significant. Conclusion Path type early rehabilitation nursing has a positive effect on the treatment of patients with cerebral infarction, which contributes to the recovery of neurological function of patients and is worthy of promotion in treatment.

scholarly journals Hyperbaric oxygen for severe traumatic brain injury: a randomized trial

2020 ◽  
Vol 48 (10) ◽  
pp. 030006052093982
Author(s):  
Xianliang Zhong ◽  
Aijun Shan ◽  
Jianzhong Xu ◽  
Jian Liang ◽  
Ying Long ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Hyperbaric Oxygen ◽  
Severe Traumatic Brain Injury ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Vital Signs ◽  
Neurological Function ◽  
Control Group ◽  
Experimental Group

Objective The present study aimed to explore the effects of hyperbaric oxygen therapy on the prognosis and neurological function of patients with severe traumatic brain injury. Methods A prospective study was carried out in 88 patients diagnosed with severe brain injury at our hospital and they were enrolled as research participants and randomly assigned to control and experimental groups (n = 44 per group) using a random number table method. Both groups underwent routine treatment. Patients in the experimental group were administered hyperbaric oxygen therapy approximately 1 week after admission when their vital signs had stabilized. Results No significant intergroup differences were observed in the Glasgow Coma Scale (GCS) and U.S. National Institutes of Health Stroke Scale (NIHSS) scores before treatment. However, after oxygen treatment, compared with the control group, the experimental group showed higher GCS and lower NIHSS scores. The GCS score at admission, tracheotomy status, and first hyperbaric oxygen therapy duration were independent prognostic factors in patients with severe traumatic brain injury. Conclusion Hyperbaric oxygen therapy may promote recovery of neurological function and improve the cognitive function and prognosis of patients with severe traumatic brain injury.

scholarly journals A combination of ultrasonic debridement and Shenghong wet dressing in patients with chronic ulcers of the lower limbs

2019 ◽  
Vol 47 (10) ◽  
pp. 4656-4663
Author(s):  
Xie Xiaolan ◽  
Guan Wujie ◽  
Tang Xiaoyan ◽  
Chang Wenlai
Keyword(s):  
Clinical Efficacy ◽  
Ulcer Healing ◽  
Lower Limbs ◽  
Control Group ◽  
Pain Intensity Score ◽  
Ulcer Healing Rate ◽  
Patients With Diabetes ◽  
Chronic Ulcers ◽  
The Mean ◽  
Experimental Group

Objective This study aimed to examine the effects of ultrasonic debridement plus a wet dressing of Shenghong (SH) on chronic ulcer healing of the lower extremities in patients with diabetes. Methods Sixty cases of diabetes combined with chronic lower limb ulcers were randomly divided into control (n = 30) and experimental (n = 30) groups. The control group was treated with ultrasonic debridement plus recombinant human fibroblast growth factor (FGF) gel. The experimental group was treated with ultrasonic debridement plus SH wet dressing. Results The mean clinical efficacy in the experimental group was significantly higher than that in the control group (93.33% ± 6.32% versus 60.0% ± 5.87%). The mean ulcer area was significantly smaller and the mean ulcer healing rate was significantly shorter in the first 3 months, and the mean overall pain intensity score was significantly lower in the experimental group than in the control group. Moreover, the positive rates of bacterial culture on the 7th and 15th days were significantly lower in the experimental group than in the control group. Conclusion The use of ultrasonic debridement plus SH wet dressing for treating ulcers can significantly improve clinical efficacy and promote healing.

The Effect of Using an Electric Fan on Dyspnea in Chinese Patients With Terminal Cancer

2016 ◽  
Vol 34 (1) ◽  
pp. 42-46 ◽  
Author(s):  
Sio Leng Wong ◽  
Sok Man Leong ◽  
Cheng Man Chan ◽  
Sut Peng Kan ◽  
Hon Wai Benjamin Cheng
Keyword(s):  
Advanced Cancer ◽  
Large Scale ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Relevant Literature ◽  
Chinese Patients ◽  
Control Group ◽  
Significant Difference ◽  
Before And After ◽  
Experimental Group

Background: Fan therapy is often suggested for relieving the symptom of dyspnea in patients with advanced cancer, but relevant literature among Asians is limited. Objective: Phase 2 clinical trial to assess the clinical feasibility and outcome of using an electric fan to alleviate the symptom of dyspnea in Chinese patients with advanced cancer. Methods: Thirty patients with advanced cancer having unresolved breathlessness were recruited from Hospice and Palliative Care Centre of Kiang Wu Hospital in Macau. Participants were randomly and equally allocated to the experimental group and the control group, respectively. Outcome Measures: Verbal numerical rating scale (NRS) of breathlessness, respiratory rate (RR), and saturation of peripheral oxygen (SpO2) was collected before and after the intervention. Results: T test was used to analyze the data collected. There was a significant difference in the NRS scores of the experimental group ( P < .01), indicating a significant reduction in the patients’ sensation of breathlessness after fan therapy, whereas no significant difference was found in the objective statistic results of RR and SpO2. No significant difference ( P > .05) was found in the control group for all the 3 variables before and after routine treatment. Conclusion: The results of the study suggested that fan therapy could be effective in alleviating dyspnea in Chinese patients with advanced cancer. It should be considered as one of the nonpharmacological treatment option. Future large-scale phase 3 clinical trials are warranted.

scholarly journals Effects of environmental distractors on nurse emergency triage accuracy: a pilot study

2020 ◽  
Author(s):  
philippe delmas ◽  
Assunta fiorentino ◽  
matteo antonini ◽  
severine Vuilleumier ◽  
guy Stotzer ◽  
...  
Keyword(s):  
Pilot Study ◽  
Large Scale ◽  
Clinical Decision Making ◽  
Clinical Decision ◽  
Serious Game ◽  
Control Group ◽  
Emergency Nurses ◽  
Group B ◽  
Experimental Group ◽  
Nurse Triage

Abstract Background: Patient safety is a top priority of the health professions. In emergency departments, the clinical decision making of triage nurses must be of the highest reliability. However, studies have repeatedly found that nurses over- or undertriage a considerable portion of cases, which can have major consequences for patient management. Among the factors that might explain this inaccuracy, workplace distractors have been pointed to without ever being the focus of specific investigation, owing in particular to the challenge of assessing them in care settings. Consequently, the use of a serious game reproducing a work environment comprising distractors would afford a unique opportunity to explore their impact on the quality of nurse emergency triage. Methods/Design : A factorial design will be used to test the acceptability and feasibility of a serious game created to explore the primary effects of distractors on emergency nurse triage accuracy. A sample of 80 emergency nurses will be randomised across three experimental groups exposed to different distractor conditions and one control group not exposed to distractors. Specifically, experimental group A will be exposed to noise distractors only; experimental group B to task interruptions only; and experimental group C to both types combined. Each group will engage in the serious game to complete 20 clinical vignettes in two hours. For each clinical vignette, a gold standard will be determined by experts. Pre-tests will be planned with clinicians and specialised emergency nurses to examine their interaction with the first version of the serious game. Discussion : This study will shed light on the acceptability and feasibility of a serious game in the field of emergency triage. It will also advance knowledge of the possible effects of exposure to common environmental distractors on nurse triage accuracy. Finally, this pilot study will inform planned large-scale studies of emergency nurse practice using serious games.

scholarly journals Ivermectin as Pre-exposure Prophylaxis for COVID-19 among Healthcare Providers in a Selected Tertiary Hospital in Dhaka – An Observational Study

2020 ◽  
Vol 2 (6) ◽  
Author(s):  
Mohammed Tarek Alam ◽  
Rubaiul Murshed ◽  
Pauline Francisca Gomes ◽  
Zafor Md. Masud ◽  
Sadia Saber ◽  
...  
Keyword(s):  
Observational Study ◽  
Large Scale ◽  
Statistical Significance ◽  
Healthcare Providers ◽  
Tertiary Hospital ◽  
Control Group ◽  
P Value ◽  
Chi Square ◽  
Exposure Prophylaxis ◽  
Experimental Group

Introduction: While multiple vaccines are undergoing clinical trial across the globe, we yearn for an FDA approved drug to protect us from the devastating pandemic for the time being. This study aims to determine the effectiveness of Ivermectin when administered as pre-exposure prophylaxis for COVID-19. Method: An observational study, with 118 healthcare providers who were enrolled purposively, was conducted in a tertiary hospital in Dhaka from May 2020 to August 2020. The subjects were divided into experimental and control groups; and the experimental group received an oral monthly dose of Ivermectin 12mg for 4 months. Both groups were exposed to COVID-19 positive patients admitted in the hospital during the course of study. The symptomatic subjects were evaluated by physical examination, COVID-19 RT-PCR and/or HRCT of chest. Differences between the variables were determined using the Chi-square test and the level of statistical significance was reached when p<0.05. Result: 73.3% (44 out of 60) subjects in control group were positive for COVID-19, whereas only 6.9% (4 out of 58) of the experimental group were diagnosed with COVID-19 (p-value < 0.05). Conclusion: Ivermectin, an FDA-approved, safe, cheap and widely available drug, should be subjected to large-scale trials all over the world to ascertain its effectiveness as pre-exposure prophylaxis for COVID-19.

scholarly journals Effect of Buyang Huanwu Decoction Combined with Acupuncture on Sequelae of Cerebral Stroke

2020 ◽  
Vol 185 ◽  
pp. 03018
Author(s):  
Jian Guo ◽  
Deqi Ren ◽  
Xuehui Chang
Keyword(s):  
Barthel Index ◽  
Clinical Effect ◽  
Effective Rate ◽  
Control Group ◽  
Cerebral Stroke ◽  
Clinical Effects ◽  
Buyang Huanwu Decoction ◽  
Nihss Score ◽  
Significant Difference ◽  
Experimental Group

Objective: To explore the clinical effect of the combined use of Buyang Huanwu Decoction and acupuncture in the treatment of patients with sequelae of stroke. Methods: The research work was carried out in our hospital. The study started from September 2018 to September 2019. A total of 100 patients were selected and randomly grouped into experimental group and control group, both groups were given Buyang Huanwu Decoction for intervention, the experimental group were added acupuncture treatment methods on this basis to explore the clinical effects of different intervention methods. Results: There were 4 patients with ineffective treatment in the experimental group, the effective rate was 92.00%, and the effective rate in the control group was 74.00%. The effective rate of the experimental group was higher, and the data was significantly different (P<0.05). After treatment, the FMA, NIHSS score and Barthel index of the patients in the experimental group were (32.66±6.51), (7.11±3.54) and (90.34±9.87) respectively. The FMA score and Barthel index were significantly higher than the control group, and the NIHSS score was lower than the control group, data differences are significant (P<0.05). At the same time, before treatment, there was no significant difference in the scores of TCM syndromes. After treatment, the patients in the experimental group had less hemiplegia, skewed eyes and mouth, eccentric sensation abnormality and consciousness coma scores than that of the control group. The data difference is quite large (P<0.05), the experimental group had better effect. Conclusion: The combined treatment of Buyang Huanwu Decoction and acupuncture in the treatment of patients with sequelae of stroke has a significant clinical effect, which can improve the quality of life of patients, improve the nerve function of patients, and have a positive effect on clinical development.

The impact of strength training on the improvement of jumping ability and selected power parameters of the lower limbs in soccer players

2021 ◽  
Vol 13 (1) ◽  
pp. 83-90
Author(s):  
PATRICIA FISCHEROVA ◽  
MAGDALENA NITYCHORUK ◽  
WOJCIECH SMOLKA ◽  
MARCIN ZAK ◽  
ARTUR GOLAS ◽  
...  
Keyword(s):  
Strength Training ◽  
Training Program ◽  
Body Height ◽  
Skills Training ◽  
Lower Limbs ◽  
Soccer Players ◽  
Control Group ◽  
Football Training ◽  
The Impact ◽  
Experimental Group

Introduction: The aim of the study was to compare the impact of a 6-week program combined with football training and strength training on strength and power parameters in highly trained soccer players. It was hypothesized that 6 weeks would be enough for the experimental group to improve their jumping ability and pushing power. Material and methods: The study involved 34 female footballers playing in Ekstraliga (age: 22 ± 5 years; body height: 167 ± 5 cm; body weight: 60 ± 8 kg). The contestants were divided into an experimental group and a control group of 17 people in each group. The control group performed football trainings combined with 2 additional strength units (50% 1RM load) 3 times a week. The experimental group, apart from football trainings, additionally performed 2 strength trainings per week (50–85% 1RM load). Results: The results of the experiment show a significant improvement in the height of the vertical jump and bench press while sitting in the experimental group CMJ (p <0.05; p = 0.000029; ES: 1.00; 11%), CMJA (p <0.05; p = 0 00003; ES = 1.09; 13%), and LP (p <0.05; p = 0.027681; ES = 0.48; 6%), while in the control group the changes in the results after the training program were statistically insignificant CMJ (p> 0.05; p = 0.274000; ES: 0.07, 1%), CMJA (p> 0.05; p = 0.350958 ES = 0.27, 3%), and LP (p> 0.05; p = 0.130153; ES = 0.27; 4%). Conclusion: The presented research results suggest that a short, six-week training program including general football training and strength training performed twice a week with loads gradually increasing during the preparatory period may significantly improve the strength and jumping parameters of the lower limbs in soccer players. Such information can be valuable at the stage of training in the field of special skills training in football.

scholarly journals Effect of Early Enteral Nutrition Support on Nitrogen Balance and Nihss Score in Elderly Patients With Acute Cerebral Stroke and Dysphagia

Pteridines ◽  
2018 ◽  
Vol 29 (1) ◽  
pp. 91-96
Author(s):  
Gao Xiaorong ◽  
Shi Ning ◽  
Yuanfang Yao
Keyword(s):  
Elderly Patients ◽  
Nitrogen Balance ◽  
Nutrition Support ◽  
Control Group ◽  
Early Enteral Nutrition ◽  
Cerebral Stroke ◽  
Nihss Score ◽  
Enteral Nutrition Support ◽  
Experimental Group ◽  
Acute Cerebral Stroke

AbstractThe aim of this study was to evaluate the clinical efficacy of early enteral nutrition support (EENS) on nitrogen balance and National Institute of Health stroke scale (NIHSS) in elderly patients with acute cerebral stroke and dysphagia. Sixty-eight patients diagnosed with acute brain stroke (ABS) were retrospectively analyzed in our hospital database. Of the included 68 ABS subjects, 37 patients were given early EENS within 72h after ABS diagnosis (experiment group) and the other 31 cases were given a regular liquid diet (control group). The nitrogen balance 1, 2, 3 and 4 weeks after EENS were -4.3 ± 1.3, -3.4 ± 1.1, -2.6 ± 1.2 and -2.0 ± 1.1(g/d) respectively for the experiment group and -8.5 ± 3.1, -7.0 ± 2.4, -6.2 ± 1.5 and -5.7 ± 1.1 (g/d) respectively for the control group. This indicated that the nitrogen balance in the experimental group was significantly higher than that of the control group (p<0.05). After treatment, the NIHSS score were 7.3 ± 2.3 and 7.4 ± 2.4 in the experimental and control groups respectively with statistically significant difference (p<0.05). The risk of developing regurgitation, diarrhea and ventosity in the experimental group were significantly lower than that of the control group (p<0.05). EENS can quickly improve the burden of ABS in elderly patients, elevate the nutritional level and reduce the risk of related complications.

scholarly journals ‘Dexamethasone–mannitol–hyperbaric oxygen’ combination therapy is effective for patients with delayed neurological sequelae after acute carbon monoxide poisoning

2021 ◽  
Vol 26 (3) ◽  
pp. 545-552
Author(s):  
Dazhi Guo ◽  
Ruijun Xue ◽  
Ya’nan Qi ◽  
Yan Lv ◽  
Xiang'en Meng ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Combination Therapy ◽  
Hyperbaric Oxygen ◽  
Mmse Score ◽  
Remission Rate ◽  
Carbon Monoxide Poisoning ◽  
Control Group ◽  
Neurological Sequelae ◽  
Nihss Score ◽  
Experimental Group

Background: Delayed neurological sequelae after carbon monoxide poisoning (DNS) is the most common neuropsychiatric sequelae of acute carbon monoxide (CO) poisoning. At present, there is no effective method to prevent or treat DNS. This study was performed to evaluate the efficacy of the combined application of dexamethasone, mannitol and hyperbaric oxygen (HBO2) in the treatment of patients with DNS. Methods: A total of 312 patients with DNS were recruited and randomly assigned into the experimental group (10 mg/day dexamethasone, 100 ml/12 h mannitol + HBO2 therapy) and the control group (HBO2 only). All patients received conventional treatment. We used the Mini-Mental State Examination (MMSE) scale to assess the cognitive function, the remission rate (RR) to assess the clinical efficacy and the National Institutes of Health Stroke Scale (NIHSS) to assess the neurological function. In addition, we measured myelin basic protein (MBP) levels in the cerebrospinal fluid (CSF) to assess the extent of nerve damage. Results: Compared with the control group, the experimental group had significantly increased average MMSE score (P = 0.035) and RR (P = 0.021), significantly reduced average NIHSS score (P = 0.028) and significantly lower MBP level in CSF (P = 0.0019) after 4 weeks of treatment. Furthermore, compared with patients who received dexamethasone alone, patients who received dexamethasone and mannitol had higher average MMSE score (P = 0.012) and RR (P = 0.038) and lower average NIHSS score (P = 0.022) and MBP level in CSF (P = 0.002). Dexamethasone and mannitol combined with HBO2 did not significantly increase adverse effects. Conclusion: The combination therapy of dexamethasone–mannitol–HBO2 is better in treating DNS than HBO2 alone and HBO2 combination with dexamethasone, and it can be used as a potential new therapy in the future.

Sign in / Sign up

Export Citation Format

Share Document