Determination of neonatal case-specific fatality rates in a tertiary health institution in North Central Nigeria

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
L. I. Audu ◽  
A. T. Otuneye ◽  
A. B. Mairami ◽  
M. Mukhtar-Yola ◽  
L. J. Mshelia

Abstract Background The current neonatal mortality rate in Nigeria (37/1000) is among the highest in the world and the major causes have consistently been reported as sepsis, perinatal asphyxia and prematurity. However, case-specific fatality which defines the risk of dying from these and other neonatal morbidities is rarely emphasized. Determination of case-specific fatality rates (CSFR) may inform a change in our current approach to neonatal care interventions which may eventually bring about the much-needed reduction in our neonatal mortality rate. Our aim was to determine the case-specific fatality rates for the common causes of mortality among hospitalized neonates at the National Hospital Abuja (NHA). Methods Relevant demographic and clinical data on all neonates admitted into the NICU at the NHA over a period of 13 months (January 2017 to February 2018) were extracted from the Neonatal Registry database and analyzed using appropriate statistical methods with the SPSS version 20 software. The case-specific fatality rates were computed for the predominant morbidities in addition to determination of the neonatal mortality rates and associated risk factors. Results and conclusion A total of 730 neonates were admitted, out of which 391 (53.6%) were females, 396 (54.5%) were inborn and 396 (54.2%) were term. The three most prevalent morbidities were prematurity 272(37.2%), neonatal Jaundice 208(28.4%) and perinatal asphyxia 91(12.5%) while the most common causes of mortality were prematurity 47/113(41.6%), congenital malformations 27/113(23.9%) and perinatal asphyxia 26/113(23%). Congenital malformations had the highest case-specific fatality 27/83(32.5%) followed by Perinatal Asphyxia 26/91(28.6%) and prematurity 47/272(20.7%). The mortality pattern differed between inborn and out born babies. Implications of these case-specific fatality rates for targeted interventions are discussed.

2020 ◽  
Author(s):  
Lamidi Audu ◽  
Adekunle Otuneye ◽  
Amsa Mairami ◽  
Mariya Mukhtar-Yola ◽  
Lauretta Mshelia

Abstract Background The current neonatal mortality rate in Nigeria (37/1000) is among the highest in the world and the major causes have consistently been reported as sepsis, perinatal asphyxia and prematurity. However, case-specific fatality which defines the risk of dying from these and other neonatal morbidities is rarely emphasized. Determination of case-specific fatality rates (CSFR) may inform a change in our current approach to neonatal care interventions which may eventually bring about the much-needed reduction in our neonatal mortality rate. Our aim was to determine the case-specific fatality rates for the common causes of mortality among hospitalized neonates at the National Hospital Abuja (NHA).Methods: Relevant demographic and clinical data on all neonates admitted into the NICU at the NHA over a period of 13 months (January 2017 to February 2018) were extracted from the Neonatal Registry database and analyzed using appropriate statistical methods with the SPSS version 20 software. The case-specific fatality rates were computed for the predominant morbidities in addition to determination of the neonatal mortality rates and associated risk factors.Results and conclusion: A total of 730 neonates were admitted, out of which 391 (53.6%) were females, 396 (54.5%) were inborn and 396 (54.2%) were term. The three most prevalent morbidities were prematurity 272(37.2%), neonatal Jaundice 208(28.4%) and perinatal asphyxia 91(12.5%) while the most common causes of mortality were prematurity 47/113(41.6%), congenital malformations 27/113(23.9%) and perinatal asphyxia 26/113(23%). Congenital malformations had the highest case-specific fatality 27/83(32.5%) followed by Perinatal Asphyxia 26/91(28.6%) and prematurity 47/272(20.7%). The mortality pattern differed between inborn and out born babies. Implications of these case-specific fatality rates for targeted interventions are discussed.


Author(s):  
Kareem Abiodun John ◽  
Fasoranti Ifedayo Olabisi ◽  
Alonge Abel Olumuyiwa ◽  
Kareem Adesola Olawumi ◽  
Bewaji Temitayo Olubunmi ◽  
...  

Background: The neonatal mortality rate remains high in developing countries despite the significant reduction in under-five mortality globally. Therefore, periodic evaluations on the causes of mortality are an aspect of health status, which could be performed to improve the neonatal mortality rate. Objectives: The present study aimed to determine the pattern and causes of neonatal mortality in the Federal Medical Center in Owo, Ondo State, Southwest Nigeria. Methods: This retrospective study was conducted using the hospital records of the neonates admitted over a five-year period from 1st of January 2015 to 31st of December 2019. Results: In total, 2,065 neonates were admitted, including 208 cases of neonatal deaths. Mortality occurred in 127 males (61.1%) and 81 females (38.9%), with the male-to-female ratio of 1.6:1. Among the recorded deaths, 114 cases (54.8%) occurred within the first 24 hours of admission, while 94 neonates (45.2%) died after 24 hours of admission. In addition, the mortality rate was higher among outborn neonates (n = 120; 57.7%) compared to inborn neonates (n = 88; 42.3%). The major causes of neonatal deaths included birth asphyxia (46.6%), prematurity (23.1%), and sepsis (17.8%). The overall mortality rate over the five-year period was 10.1%, which is equivalent to 19 deaths per 1,000 live births. Conclusions: According to the results, preventable diseases such as birth asphyxia, prematurity, and sepsis remain the major causes of neonatal mortality, of which neonatal deaths occur mostly within 24 hours of admission.


Author(s):  
Mehrdad Mirzarahimi ◽  
Afsaneh Enteshari- Moghaddam ◽  
Sepideh Khademi

Background: Neonatal mortality rate (NMR) is one of the important parameters in assessing quality of life in societies. NMR are often used as a standard index for evaluation health, education and social systems, nutritional status and health programs for neonates in countries and the first step in reducing mortality rate and promoting the level of this indicator is to identify the causes of mortality. Therefore, this study was conducted to determine the NMR in new born infants admitted to the ICU of Ardabil city hospitals.Methods: This study was a descriptive cross-sectional study that has been done on 184 dead neonates in Ardabil city hospital during 2016-2017. The necessary information was extracted from the hospital records of neonates and entered in a provided checklist and then analyzed by statistical methods such as tables in SPSS version 19.Results: The mortality rate of hospitalized infants in this research was 6.6%. Of all patients, in 65.2% CBC were impaired and 58.7% of patients had impaired serologic and biochemical tests. 68.5% of patients had prematurity, 62.5% RDS and 20.7% had congenital anomalies.Conclusions: Prematurity, RDS and congenital anomalies are the most important causes of NMR and we should programing to decreasing the NMR rate in future.


Author(s):  
Özgün Uygur ◽  
Fırat Ergin ◽  
Meltem Koyuncu Arslan ◽  
Deniz Gönülal ◽  
Sümer Sütçüoğlu ◽  
...  

Objective: Nowadays, the neonatal mortality rate which is a national health problem can be reduced, especially in premature infants, thanks to improved patient care and appropriate treatments. The aim of this study was to determine the mortality rate and causes of mortality in our neonatal intensive care unit (NICU) during the last five years. Method: Newborns lost between January 1, 2014 and December 31, 2018 in the NICU of İzmir Tepecik Training and Research Hospital were included in the study. Demographic data, duration of hospital stay, prenatal risk factors, mode of delivery, presence of congenital anomaly, causes of mortality and mortality rate were determined. Results: The records of 4155 infants hospitalized between January 1, 2014 and December 31, 2018 were investigated and a total of 382 neonates who were lost during their stay in the NICU were included in the study. With these results, the five-year mortality rate in our neonatal intensive care unit was calculated as 9.1%. The average duration of hospitalization was 24.5 days (1-384). While prematurity / RDS was the most common cause of neonatal death, the other most common causes were sepsis/multiorgan failure, genetic causes and congenital heart diseases. Conclusion: Although the neonatal mortality rate is reduced with the improvement of perinatal-antenatal care besides technological improvements, health policy regulations are needed to decrease the neonatal mortality rate due to the increasing number of infants requiring major surgery.


PEDIATRICS ◽  
1996 ◽  
Vol 97 (2) ◽  
pp. 215-215
Author(s):  
Student

Neonates who weighed > 1.5 kg at birth were the major contributors to the overall reduction in the neonatal mortality rate (NMR); approximately two thirds of total reduction in the NMR between 1960 and 1980 and 52.6% of the total reduction between 1980 and 1986 occurred in the > 1.5-kg birth weight groups.


2016 ◽  
Vol 127 ◽  
pp. 31S
Author(s):  
Horatio S. Falciglia ◽  
William K. Brady ◽  
Ronald Merkel ◽  
Vickie Glover ◽  
Angela N. Fellner

2004 ◽  
Vol 38 (6) ◽  
pp. 773-779 ◽  
Author(s):  
Valdinar S Ribeiro ◽  
Antônio A M Silva ◽  
Marco A Barbieri ◽  
Heloisa Bettiol ◽  
Vânia M F Aragão ◽  
...  

OBJECTIVE: To obtain population estimates and profile risk factors for infant mortality in two birth cohorts and compare them among cities of different regions in Brazil. METHODS: In Ribeirão Preto, southeast Brazil, infant mortality was determined in a third of hospital live births (2,846 singleton deliveries) in 1994. In São Luís, northeast Brazil, data were obtained using systematic sampling of births stratified by maternity unit (2,443 singleton deliveries) in 1997-1998. Mothers answered standardized questionnaires shortly after delivery and information on infant deaths was retrieved from hospitals, registries and the States Health Secretarys' Office. The relative risk (RR) was estimated by Poisson regression. RESULTS: In São Luís, the infant mortality rate was 26.6/1,000 live births, the neonatal mortality rate was 18.4/1,000 and the post-neonatal mortality rate was 8.2/1,000, all higher than those observed in Ribeirão Preto (16.9, 10.9 and 6.0 per 1,000, respectively). Adjusted analysis revealed that previous stillbirths (RR=3.67 vs 4.13) and maternal age <18 years (RR=2.62 vs 2.59) were risk factors for infant mortality in the two cities. Inadequate prenatal care (RR=2.00) and male sex (RR=1.79) were risk factors in São Luís only, and a dwelling with 5 or more residents was a protective factor (RR=0.53). In Ribeirão Preto, maternal smoking was associated with infant mortality (RR=2.64). CONCLUSIONS: In addition to socioeconomic inequalities, differences in access to and quality of medical care between cities had an impact on infant mortality rates.


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