scholarly journals Income, inflammation and cancer mortality: a study of U.S. National Health and Nutrition Examination Survey mortality follow-up cohorts

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Joshua E. Chan ◽  
Amandeep K. Mann ◽  
Daniel S. Kapp ◽  
David H. Rehkopf
Keyword(s):  
National Health ◽  
Low Income ◽  
Cancer Mortality ◽  
Inflammatory Biomarkers ◽  
Nutrition Examination Survey ◽  
Complete Control ◽  
Health And Nutrition ◽  
Nationally Representative ◽  
The Relationship ◽  
The U.S

Abstract Background To estimate the relationship between inflammatory biomarkers and cancer mortality in a nationally representative sample of the U.S. population while controlling for education, occupation, and income. Methods Data were obtained from the U.S. National Health and Nutrition Examination Survey from 1988 to 1994 (N = 7817) and 1999–2002 (N = 2344). We fit Cox proportional hazard models to examine the relationship between C-reactive protein (CRP) and fibrinogen with cancer mortality. Results In the full Cox multivariate model, clinically raised CRP was associated with cancer mortality in NHANES 1988–1994 (> 0.99 mg/dL: 95%CI: 1.04–2.13). However, across two inflammatory biomarkers (CRP and Fibrinogen), two NHANES time periods (1998–1994 and 1999–2002) and three income levels (12 strata in total), Hazard ratio confidence intervals did not include the null only for one association: CRP and cancer mortality among low income participants from 1988 to 1994 (HR = 1.83, 95% CI: 1.10–3.04). Conclusions We find evidence that only in one unique stratum is earlier life CRP, and not fibrinogen, associated with prospective cancer mortality. After more complete control for socioeconomic confounding, CRP and fibrinogen do not predict cancer mortality in most subpopulations.

scholarly journals Social isolation, inflammation, and cancer mortality from the National Health and Nutrition Examination Survey - a study of 3,360 women

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Alexander Koh-Bell ◽  
Joshua Chan ◽  
Amandeep K. Mann ◽  
Daniel S. Kapp
Keyword(s):  
Physical Activity ◽  
Social Isolation ◽  
National Health ◽  
Low Income ◽  
Cancer Mortality ◽  
Nutrition Examination Survey ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Health And Nutrition ◽  
Markers Of Inflammation

Abstract Background This study evaluates the role of social isolation on inflammation and cancer mortality among women. Methods Data were abstracted from the U.S. National Health and Nutrition Examination Survey from 1988 to 1994. The Social Network Index was used to assess participants’ degree of social isolation. C-reactive protein and fibrinogen levels were included as markers of inflammation. We used the National Death Index to identify causes and dates of mortality. Chi-square and multivariable Cox regressions were employed for statistical analyses. Results Of 3360 women (median age: 54 years), the most isolated, very isolated, somewhat isolated, and not isolated comprised 14.5, 30.2, 37.1, and 18.2% of the sample, respectively. The most isolated participants were more likely to have low income (56.8% vs 12.2%, p < 0.001), have fewer years of education (40.8% vs 12.3%; p < 0.001), have low physical activity (27.3% vs 14.7%; p < 0.003), be obese (32.5% vs 24.4%; p = 0.02), and be current smokers (34.2% vs 10.3%; p < 0.001) compared to the not isolated ones. Mean fibrinogen levels increased with degree of social isolation (p = 0.003), but C-reactive protein showed no association (p = 0.52). Kaplan-Meier estimates indicated higher cancer mortality rates among participants with elevated fibrinogen levels, though not with statistical significance (p = 0.08). Furthermore, there was no association between social isolation and cancer mortality (p = 0.54). On multivariate analysis, obesity (HR = 1.56; 95% CI: 1.11–2.18), higher education (HR = 1.36; 95% CI: 1.01–1.83), and smoking (HR = 4.42, 95% CI: 2.84–6.88) were independent predictors for cancer mortality, while high physical activity predicted for lower mortality from cancer (HR = 0.67, 95% CI: 0.51–0.87). However, social isolation was not a predictor. Conclusion Social isolation among women was associated with an increased level of fibrinogen, but not associated with cancer mortality. The relationship between inflammation and cancer mortality warrants further investigation.

scholarly journals Quantitation of Trans-Fatty Acids in Children from the National Health and Nutrition Examination Survey

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 221-221
Author(s):  
Heather Kuiper ◽  
Na Wei ◽  
John Goodwin ◽  
Tunde Frame ◽  
Yang Liu ◽  
...  
Keyword(s):  
Fatty Acids ◽  
National Health ◽  
Trans Fatty Acids ◽  
Partial Hydrogenation ◽  
Ionization Mass ◽  
Nutrition Examination Survey ◽  
Blood Concentrations ◽  
Health And Nutrition ◽  
Nationally Representative ◽  
The U.S

Abstract Objectives Trans-fatty acids (TFA) are geometric isomers of naturally occurring cis-fatty acids, formed industrially through partial hydrogenation of vegetable oils or naturally in ruminant animals. TFA intake has been associated with risk factors for cardiovascular disease; therefore, reduced TFA consumption is a major public health objective. Food intake studies have provided estimates for TFA levels in the U.S. and we previously assessed TFA blood concentrations in fasting U.S. adults in the National Health and Nutrition Examination Survey (NHANES), finding an average 54% decrease in TFA between 1999–2000 and 2009–2010. The aim of this study was to determine nationally representative estimates for plasma TFA concentrations in children in the U.S. population. Methods We used the CDC isotope dilution-gas chromatography-negative chemical ionization-mass spectrometry (ID-GC-NCI-MS) method to quantitate four major TFA, palmitelaidic acid, elaidic acid, trans-vaccenic acid, and linoelaidic acid, in a nationally representative group of children in the U.S. population using NHANES samples. TFA were derivatized with pentafluorobenzyl-bromide and analyzed by GC-MS in selected ion monitoring mode using NCI with methane reagent gas. Separation was carried out on a Select FAME 200 m column with hydrogen carrier gas. The TFA limits of detection ranged from 0.02 μM to 0.43 μM. The intraday and inter-day % coefficients of variation ranged from 1–11%  CV and 6–15% CV respectively. The mean accuracy for all four TFA was 102% (95% CI: 98%–107%). Results The TFA were measured in 916 participants (age: 6–19 years) from NHANES 1999–2000 and 1718 participants (age: 3–19 years) from NHANES 2009–2010, and were detected in all samples. Geometric means for the sum of the 4 TFAs were 80.7 μmol/l (95% CI: 74.6–87.3 μmol/L) and 30.6 μmol/l (95% CI: 29.0–32.3 μmol/L) in the NHANES 1999–2000 and 2009–2010, respectively. Overall TFA concentrations were 62% lower in NHANES 2009–2010 compared to 1999–2000. Conclusions TFA levels in children in the U.S. population are notably lower in NHANES 2009–2010 compared to NHANES 1999–2000 suggesting an overall reduction of TFA levels in children. Funding Sources N/A.

On the Relationship between Handedness and Season of Birth for Men

1994 ◽  
Vol 79 (1) ◽  
pp. 499-506 ◽  
Author(s):  
Peter A. Rogerson
Keyword(s):  
National Health ◽  
Early Summer ◽  
Nutrition Examination Survey ◽  
Season Of Birth ◽  
Baseball Players ◽  
Health And Nutrition ◽  
Left Handed ◽  
The Relationship ◽  
The U.S

A sample of 8,929 male baseball players and a sample of 2,234 males from the U.S. National Health and Nutrition Examination Survey are used to assess the relation between handedness and season of birth. The results, when coupled with a further examination of the 1991 data of Dellatolas, Curt, and Lellouch, lead to the conclusion that those born during the spring and early summer are more likely to be left-handed than are those born during the fall and winter.

scholarly journals Social Isolation, Inflammation, and Cancer Mortality from the National Health and Nutrition Examination Survey - A Study of 3,446 Women

2021 ◽  
Author(s):  
Alexander Koh-Bell ◽  
Joshua Chan ◽  
Amandeep K. Mann ◽  
Daniel S. Kapp
Keyword(s):  
Physical Activity ◽  
Social Isolation ◽  
National Health ◽  
Low Income ◽  
Cancer Mortality ◽  
Nutrition Examination Survey ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Health And Nutrition ◽  
Markers Of Inflammation

Abstract Background To evaluate the relationships of social isolation, inflammatory biomarkers, and cancer mortality among women.Methods Data were abstracted from the U.S. National Health and Nutrition Examination Survey from 1988-1994. The Social Network Index was used to assess participants’ degree of social isolation. C-reactive protein and fibrinogen levels were included as markers of inflammation. We used the National Death Index to identify causes and dates of mortality. Chi-square and multivariable Cox regressions were employed for statistical analyses.Results Of 3,446 women (median age: 55 years), the most isolated, very isolated, somewhat isolated, and not isolated comprised 14.5%, 30.3%, 37.0%, and 18.2% of the sample, respectively. The most isolated participants were more likely to have low income (57.1% vs 12.2 %, p<0.001), have fewer years of education (40.6% vs 12.2%; p<0.001), have low physical activity (27.3% vs 14.6%; p<0.003), be obese (32.3% vs 24.2%; p=0.02), and be current smokers (33.8% vs 10.2 %; p<0.001) compared to the not isolated ones. Mean fibrinogen levels increased with degree of social isolation (p=0.02), but C-reactive protein showed no association (p=0.58). Kaplan-Meier estimates indicated higher cancer mortality rates among participants with elevated fibrinogen levels, though not statistically significant (p=0.07). Furthermore, there was no correlation between social isolation and cancer mortality (p=0.55). On multivariate analysis, obesity (HR=1.39; 95% CI: 1.05-1.83; p=0.02) and lower education (HR=1.48; 95% CI: 1.04-2.11; p=0.03) were independent predictors for cancer mortality, while high physical activity predicted for lower mortality from cancer (HR=0.67, 95% CI: 0.49-0.91; p=0.01). However, social isolation was not a predictor (p=0.88).Conclusion Social isolation among women was associated with an increased level of fibrinogen, but not associated with cancer mortality. The relationship between inflammation and cancer mortality warrants further investigation.

scholarly journals Socioeconomic Disparities in Foods/Beverages and Nutrients Consumed by U.S. Adolescents When Snacking: National Health and Nutrition Examination Survey 2005–2018

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2530
Author(s):  
Navika Gangrade ◽  
Janet Figueroa ◽  
Tashara M. Leak
Keyword(s):  
National Health ◽  
Low Socioeconomic Status ◽  
Low Income ◽  
High Income ◽  
Future Research ◽  
Nutrition Examination Survey ◽  
Middle Income ◽  
Low Socioeconomic ◽  
Health And Nutrition ◽  
Income Ratio

Snacking contributes a significant portion of adolescents’ daily energy intake and is associated with poor overall diet and increased body mass index. Adolescents from low socioeconomic status (SES) households have poorer snacking behaviors than their higher-SES counterparts. However, it is unclear if the types of food/beverages and nutrients consumed during snacking differ by SES among adolescents. Therefore, this study examines SES disparities in the aforementioned snacking characteristics by analyzing the data of 7132 adolescents (12–19 years) from the National Health and Nutrition Examination Survey 2005–2018. Results reveal that adolescents from low-income households (poverty-to-income ratio (PIR) ≤ 1.3) have lower odds of consuming the food/beverage categories “Milk and Dairy” (aOR: 0.74; 95% CI: 0.58-0.95; p = 0.007) and “Fruits” (aOR: 0.62, 95% CI: 0.50–0.78; p = 0.001) as snacks and higher odds of consuming “Beverages” (aOR: 1.45; 95% CI: 1.19-1.76; p = 0.001) compared to those from high-income households (PIR > 3.5). Additionally, adolescents from low- and middle-income (PIR > 1.3–3.5) households consume more added sugar (7.98 and 7.78 g vs. 6.66 g; p = 0.012, p = 0.026) and less fiber (0.78 and 0.77 g vs. 0.84 g; p = 0.044, p = 0.019) from snacks compared to their high-income counterparts. Future research is necessary to understand factors that influence snacking among adolescents, and interventions are needed, especially for adolescents from low-SES communities.

scholarly journals Complementary and Integrative Health Approaches for Weight Management in the Obese Population: The 2018 Korea National Health and Nutrition Examination Survey

2021 ◽  
Vol 18 (15) ◽  
pp. 8161
Author(s):  
Sang-Dol Kim
Keyword(s):  
Food Intake ◽  
Weight Management ◽  
National Health ◽  
Age Group ◽  
Nutrition Examination Survey ◽  
Obesity Management ◽  
Health And Nutrition ◽  
Obese Population ◽  
Nationally Representative ◽  
Management Approaches

(1) Background: Obesity management has become an important issue due to the COVID-19 outbreak; therefore, periodic surveys on the approaches to obesity management of the entire population and target obese population are required. (2) Methods: The study used nationally representative data from the 2018 Korea National Health and Nutrition Examination Survey. Participants reported all approaches they had used to reduce or maintain weight in the past year. Data were analyzed with multiple response methods. (3) Results: The most commonly reported approach was exercise, which included fitness, yoga, biking, and other physical activities (74.7% of respondents), and the second most commonly reported approach was decreased food intake (69.6% of respondents). The use of approaches differed according to respondents’ demographic characteristics. Regarding sex-related differences, in particular, men preferred to exercise, while women were more likely to decrease food intake. Among men, exercise was highest in the 40–49 years age group (48.3%). Among women, decreased food intake was highest in the same age group (16.1%). (4) Conclusions: These findings indicate that it is necessary to introduce individualized weight management approaches and measures according to target groups in obese adults.

scholarly journals Markers of Sleep Disordered Breathing and Diabetes Mellitus in a Multiethnic Sample of US Adults: Results from the National Health and Nutrition Examination Survey (2005–2008)

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Charumathi Sabanayagam ◽  
Srinivas Teppala ◽  
Anoop Shankar
Keyword(s):  
Ethnic Differences ◽  
National Health ◽  
Sleep Disturbances ◽  
Sleep Disordered Breathing ◽  
Summary Score ◽  
Nutrition Examination Survey ◽  
Health And Nutrition ◽  
Nationally Representative ◽  
Multiethnic Sample ◽  
Disordered Breathing

We examined gender and ethnic differences in the association between sleep disordered breathing (SDB) and diabetes among 6,522 participants aged ≥20 years from the National Health and Nutrition Examination Survey 2005–08. SDB severity was defined based on an additive summary score including sleep duration, snoring, snorting, and daytime sleepiness. We found that the summary SDB score was significantly associated with diabetes after adjusting for potential confounders in the whole population. Compared to those without any sleep disturbance, the multivariable odds ratio (OR) (95% confidence interval (CI)) of diabetes among those with ≥3 sleep disturbances was 2.04 (1.46–2.87). In sex-specific analyses, this association was significant only in women (OR (95% CI) = 3.68 (2.01–6.72)) but not in men (1.10 (0.59–2.04)),P-interaction=0.01. However, there were no ethnic differences in this association,P-interaction=0.7. In a nationally representative sample of US adults, SDB was independently associated with diabetes only in women, but not in men.

Sign in / Sign up

Export Citation Format

Share Document