scholarly journals Comparison of machine learning algorithms applied to symptoms to determine infectious causes of death in children: national survey of 18,000 verbal autopsies in the Million Death Study in India

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Susan Idicula-Thomas ◽  
Ulka Gawde ◽  
Prabhat Jha
Keyword(s):  
Machine Learning ◽  
Verbal Autopsy ◽  
Causes Of Death ◽  
Prediction Models ◽  
Machine Learning Algorithms ◽  
Classification And Regression Tree ◽  
Gradient Boosting ◽  
Support Vector ◽  
Diarrhoeal Diseases

Abstract Background Machine learning (ML) algorithms have been successfully employed for prediction of outcomes in clinical research. In this study, we have explored the application of ML-based algorithms to predict cause of death (CoD) from verbal autopsy records available through the Million Death Study (MDS). Methods From MDS, 18826 unique childhood deaths at ages 1–59 months during the time period 2004–13 were selected for generating the prediction models of which over 70% of deaths were caused by six infectious diseases (pneumonia, diarrhoeal diseases, malaria, fever of unknown origin, meningitis/encephalitis, and measles). Six popular ML-based algorithms such as support vector machine, gradient boosting modeling, C5.0, artificial neural network, k-nearest neighbor, classification and regression tree were used for building the CoD prediction models. Results SVM algorithm was the best performer with a prediction accuracy of over 0.8. The highest accuracy was found for diarrhoeal diseases (accuracy = 0.97) and the lowest was for meningitis/encephalitis (accuracy = 0.80). The top signs/symptoms for classification of these CoDs were also extracted for each of the diseases. A combination of signs/symptoms presented by the deceased individual can effectively lead to the CoD diagnosis. Conclusions Overall, this study affirms that verbal autopsy tools are efficient in CoD diagnosis and that automated classification parameters captured through ML could be added to verbal autopsies to improve classification of causes of death.

scholarly journals Development of Machine Learning Models for Prediction of Smoking Cessation Outcome

2021 ◽  
Vol 18 (5) ◽  
pp. 2584
Author(s):  
Cheng-Chien Lai ◽  
Wei-Hsin Huang ◽  
Betty Chia-Chen Chang ◽  
Lee-Ching Hwang
Keyword(s):  
Machine Learning ◽  
Smoking Cessation ◽  
Success Rate ◽  
Prediction Models ◽  
Smoking Status ◽  
Medical Center ◽  
Machine Learning Algorithms ◽  
Classification And Regression Tree ◽  
Support Vector ◽  
Smoking Cessation Outcome

Predictors for success in smoking cessation have been studied, but a prediction model capable of providing a success rate for each patient attempting to quit smoking is still lacking. The aim of this study is to develop prediction models using machine learning algorithms to predict the outcome of smoking cessation. Data was acquired from patients underwent smoking cessation program at one medical center in Northern Taiwan. A total of 4875 enrollments fulfilled our inclusion criteria. Models with artificial neural network (ANN), support vector machine (SVM), random forest (RF), logistic regression (LoR), k-nearest neighbor (KNN), classification and regression tree (CART), and naïve Bayes (NB) were trained to predict the final smoking status of the patients in a six-month period. Sensitivity, specificity, accuracy, and area under receiver operating characteristic (ROC) curve (AUC or ROC value) were used to determine the performance of the models. We adopted the ANN model which reached a slightly better performance, with a sensitivity of 0.704, a specificity of 0.567, an accuracy of 0.640, and an ROC value of 0.660 (95% confidence interval (CI): 0.617–0.702) for prediction in smoking cessation outcome. A predictive model for smoking cessation was constructed. The model could aid in providing the predicted success rate for all smokers. It also had the potential to achieve personalized and precision medicine for treatment of smoking cessation.

scholarly journals Comparative Analysis of Machine Learning Algorithms for Multi-Syndrome Classification of Neurodegenerative Syndromes

2021 ◽  
Author(s):  
Leonie Lampe ◽  
Sebastian Niehaus ◽  
Hans-Jürgen Huppertz ◽  
Alberto Merola ◽  
Janis Reinelt ◽  
...  
Keyword(s):  
Machine Learning ◽  
Support Vector Machine ◽  
Performance Measures ◽  
Careful Consideration ◽  
Machine Learning Algorithms ◽  
Classification Task ◽  
Gradient Boosting ◽  
Support Vector ◽  
Learning Methods

Abstract Importance The entry of artificial intelligence into medicine is pending. Several methods have been used for predictions of structured neuroimaging data, yet nobody compared them in this context.Objective Multi-class prediction is key for building computational aid systems for differential diagnosis. We compared support vector machine, random forest, gradient boosting, and deep feed-forward neural networks for the classification of different neurodegenerative syndromes based on structural magnetic resonance imaging.Design, Setting, and Participants Atlas-based volumetry was performed on multi-centric T1weighted MRI data from 940 subjects, i.e. 124 healthy controls and 816 patients with ten different neurodegenerative diseases, leading to a multi-diagnostic multi-class classification task with eleven different classes.Interventions n.a.Main Outcomes and Measures Cohen’s Kappa, Accuracy, and F1-score to assess model performance.Results Over all, the neural network produced both the best performance measures as well as the most robust results. The smaller classes however were better classified by either the ensemble learning methods or the support vector machine, while performance measures for small classes were comparatively low, as expected. Diseases with regionally specific and pronounced atrophy patterns were generally better classified than diseases with wide-spread and rather weak atrophy.Conclusions and Relevance Our study furthermore underlines the necessity of larger data sets but also calls for a careful consideration of different machine learning methods that can handle the type of data and the classification task best.Trial Registration n.a.

In silico Prediction of Inhibitory Constant of Thrombin Inhibitors Using Machine Learning

2019 ◽  
Vol 21 (9) ◽  
pp. 662-669 ◽  
Author(s):  
Junnan Zhao ◽  
Lu Zhu ◽  
Weineng Zhou ◽  
Lingfeng Yin ◽  
Yuchen Wang ◽  
...  
Keyword(s):  
Machine Learning ◽  
Prediction Models ◽  
Regression Tree ◽  
Large Data ◽  
Thrombin Inhibitors ◽  
Coagulation Cascade ◽  
Gradient Boosting ◽  
Support Vector ◽  
Data Set ◽  
Descriptor Selection

Background: Thrombin is the central protease of the vertebrate blood coagulation cascade, which is closely related to cardiovascular diseases. The inhibitory constant Ki is the most significant property of thrombin inhibitors. Method: This study was carried out to predict Ki values of thrombin inhibitors based on a large data set by using machine learning methods. Taking advantage of finding non-intuitive regularities on high-dimensional datasets, machine learning can be used to build effective predictive models. A total of 6554 descriptors for each compound were collected and an efficient descriptor selection method was chosen to find the appropriate descriptors. Four different methods including multiple linear regression (MLR), K Nearest Neighbors (KNN), Gradient Boosting Regression Tree (GBRT) and Support Vector Machine (SVM) were implemented to build prediction models with these selected descriptors. Results: The SVM model was the best one among these methods with R2=0.84, MSE=0.55 for the training set and R2=0.83, MSE=0.56 for the test set. Several validation methods such as yrandomization test and applicability domain evaluation, were adopted to assess the robustness and generalization ability of the model. The final model shows excellent stability and predictive ability and can be employed for rapid estimation of the inhibitory constant, which is full of help for designing novel thrombin inhibitors.

scholarly journals Prediction of Healing Performance of Autogenous Healing Concrete Using Machine Learning

Materials ◽  
2021 ◽  
Vol 14 (15) ◽  
pp. 4068
Author(s):  
Xu Huang ◽  
Mirna Wasouf ◽  
Jessada Sresakoolchai ◽  
Sakdirat Kaewunruen
Keyword(s):  
Machine Learning ◽  
Search Algorithm ◽  
Weather Conditions ◽  
Prediction Performance ◽  
Machine Learning Algorithms ◽  
Coefficient Of Determination ◽  
Gradient Boosting ◽  
Support Vector ◽  
Self Healing ◽  
Artificial Neural Network Ann

Cracks typically develop in concrete due to shrinkage, loading actions, and weather conditions; and may occur anytime in its life span. Autogenous healing concrete is a type of self-healing concrete that can automatically heal cracks based on physical or chemical reactions in concrete matrix. It is imperative to investigate the healing performance that autogenous healing concrete possesses, to assess the extent of the cracking and to predict the extent of healing. In the research of self-healing concrete, testing the healing performance of concrete in a laboratory is costly, and a mass of instances may be needed to explore reliable concrete design. This study is thus the world’s first to establish six types of machine learning algorithms, which are capable of predicting the healing performance (HP) of self-healing concrete. These algorithms involve an artificial neural network (ANN), a k-nearest neighbours (kNN), a gradient boosting regression (GBR), a decision tree regression (DTR), a support vector regression (SVR) and a random forest (RF). Parameters of these algorithms are tuned utilising grid search algorithm (GSA) and genetic algorithm (GA). The prediction performance indicated by coefficient of determination (R2) and root mean square error (RMSE) measures of these algorithms are evaluated on the basis of 1417 data sets from the open literature. The results show that GSA-GBR performs higher prediction performance (R2GSA-GBR = 0.958) and stronger robustness (RMSEGSA-GBR = 0.202) than the other five types of algorithms employed to predict the healing performance of autogenous healing concrete. Therefore, reliable prediction accuracy of the healing performance and efficient assistance on the design of autogenous healing concrete can be achieved.

scholarly journals Delineating Smallholder Maize Farms from Sentinel-1 Coupled with Sentinel-2 Data Using Machine Learning

2021 ◽  
Vol 13 (9) ◽  
pp. 4728
Author(s):  
Zinhle Mashaba-Munghemezulu ◽  
George Johannes Chirima ◽  
Cilence Munghemezulu
Keyword(s):  
Machine Learning ◽  
Food Security ◽  
Rural Communities ◽  
Machine Learning Algorithms ◽  
Support Vector ◽  
Subsistence Agriculture ◽  
Smallholder Farms ◽  
Main Driver ◽  
Sentinel 2

Rural communities rely on smallholder maize farms for subsistence agriculture, the main driver of local economic activity and food security. However, their planted area estimates are unknown in most developing countries. This study explores the use of Sentinel-1 and Sentinel-2 data to map smallholder maize farms. The random forest (RF), support vector (SVM) machine learning algorithms and model stacking (ST) were applied. Results show that the classification of combined Sentinel-1 and Sentinel-2 data improved the RF, SVM and ST algorithms by 24.2%, 8.7%, and 9.1%, respectively, compared to the classification of Sentinel-1 data individually. Similarities in the estimated areas (7001.35 ± 1.2 ha for RF, 7926.03 ± 0.7 ha for SVM and 7099.59 ± 0.8 ha for ST) show that machine learning can estimate smallholder maize areas with high accuracies. The study concludes that the single-date Sentinel-1 data were insufficient to map smallholder maize farms. However, single-date Sentinel-1 combined with Sentinel-2 data were sufficient in mapping smallholder farms. These results can be used to support the generation and validation of national crop statistics, thus contributing to food security.

scholarly journals Comparison of Ensemble Machine Learning Methods for Soil Erosion Pin Measurements

2021 ◽  
Vol 10 (1) ◽  
pp. 42
Author(s):  
Kieu Anh Nguyen ◽  
Walter Chen ◽  
Bor-Shiun Lin ◽  
Uma Seeboonruang
Keyword(s):  
Machine Learning ◽  
Soil Erosion ◽  
Ensemble Methods ◽  
Machine Learning Algorithms ◽  
Multivariate Adaptive Regression Splines ◽  
Gradient Boosting ◽  
Support Vector ◽  
Ensemble Machine Learning ◽  
Boosting Method ◽  
Bagging Method

Although machine learning has been extensively used in various fields, it has only recently been applied to soil erosion pin modeling. To improve upon previous methods of quantifying soil erosion based on erosion pin measurements, this study explored the possible application of ensemble machine learning algorithms to the Shihmen Reservoir watershed in northern Taiwan. Three categories of ensemble methods were considered in this study: (a) Bagging, (b) boosting, and (c) stacking. The bagging method in this study refers to bagged multivariate adaptive regression splines (bagged MARS) and random forest (RF), and the boosting method includes Cubist and gradient boosting machine (GBM). Finally, the stacking method is an ensemble method that uses a meta-model to combine the predictions of base models. This study used RF and GBM as the meta-models, decision tree, linear regression, artificial neural network, and support vector machine as the base models. The dataset used in this study was sampled using stratified random sampling to achieve a 70/30 split for the training and test data, and the process was repeated three times. The performance of six ensemble methods in three categories was analyzed based on the average of three attempts. It was found that GBM performed the best among the ensemble models with the lowest root-mean-square error (RMSE = 1.72 mm/year), the highest Nash-Sutcliffe efficiency (NSE = 0.54), and the highest index of agreement (d = 0.81). This result was confirmed by the spatial comparison of the absolute differences (errors) between model predictions and observations using GBM and RF in the study area. In summary, the results show that as a group, the bagging method and the boosting method performed equally well, and the stacking method was third for the erosion pin dataset considered in this study.

Prediction and Analysis of Gold Prices using Ensemble Machine Learning Algorithms

2021 ◽  
Vol 9 (VI) ◽  
pp. 4367-4374
Author(s):  
Gudipally Chandrashakar
Keyword(s):  
Machine Learning ◽  
Time Series ◽  
Time Series Data ◽  
Gold Price ◽  
Machine Learning Algorithms ◽  
Series Data ◽  
Gradient Boosting ◽  
Support Vector ◽  
Average Value ◽  
Ensemble Machine Learning

In this article, we used historical time series data up to the current day gold price. In this study of predicting gold price, we consider few correlating factors like silver price, copper price, standard, and poor’s 500 value, dollar-rupee exchange rate, Dow Jones Industrial Average Value. Considering the prices of every correlating factor and gold price data where dates ranging from 2008 January to 2021 February. Few algorithms of machine learning are used to analyze the time-series data are Random Forest Regression, Support Vector Regressor, Linear Regressor, ExtraTrees Regressor and Gradient boosting Regression. While seeing the results the Extra Tree Regressor algorithm gives the predicted value of gold prices more accurately.

Classification of Diffusion Tensor Metrics for the Diagnosis of a Myelopathic Cord Using Machine Learning

2018 ◽  
Vol 28 (02) ◽  
pp. 1750036 ◽  
Author(s):  
Shuqiang Wang ◽  
Yong Hu ◽  
Yanyan Shen ◽  
Hanxiong Li
Keyword(s):  
Machine Learning ◽  
Surgical Planning ◽  
Diffusion Tensor ◽  
Mean Value ◽  
Machine Learning Algorithms ◽  
Support Vector ◽  
Svm Classifier ◽  
Control Groups ◽  
Diffusion Tensor Imaging Dti

In this study, we propose an automated framework that combines diffusion tensor imaging (DTI) metrics with machine learning algorithms to accurately classify control groups and groups with cervical spondylotic myelopathy (CSM) in the spinal cord. The comparison between selected voxel-based classification and mean value-based classification were performed. A support vector machine (SVM) classifier using a selected voxel-based dataset produced an accuracy of 95.73%, sensitivity of 93.41% and specificity of 98.64%. The efficacy of each index of diffusion for classification was also evaluated. Using the proposed approach, myelopathic areas in CSM are detected to provide an accurate reference to assist spine surgeons in surgical planning in complicated cases.

scholarly journals Predicting hospitalization following psychiatric crisis care using machine learning

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Matthijs Blankers ◽  
Louk F. M. van der Post ◽  
Jack J. M. Dekker
Keyword(s):  
Machine Learning ◽  
Logistic Regression ◽  
Prediction Models ◽  
Learning Algorithms ◽  
Nearest Neighbors ◽  
Machine Learning Algorithms ◽  
Gradient Boosting ◽  
Ensemble Model ◽  
K Nearest Neighbors ◽  
Crisis Care

Abstract Background Accurate prediction models for whether patients on the verge of a psychiatric criseis need hospitalization are lacking and machine learning methods may help improve the accuracy of psychiatric hospitalization prediction models. In this paper we evaluate the accuracy of ten machine learning algorithms, including the generalized linear model (GLM/logistic regression) to predict psychiatric hospitalization in the first 12 months after a psychiatric crisis care contact. We also evaluate an ensemble model to optimize the accuracy and we explore individual predictors of hospitalization. Methods Data from 2084 patients included in the longitudinal Amsterdam Study of Acute Psychiatry with at least one reported psychiatric crisis care contact were included. Target variable for the prediction models was whether the patient was hospitalized in the 12 months following inclusion. The predictive power of 39 variables related to patients’ socio-demographics, clinical characteristics and previous mental health care contacts was evaluated. The accuracy and area under the receiver operating characteristic curve (AUC) of the machine learning algorithms were compared and we also estimated the relative importance of each predictor variable. The best and least performing algorithms were compared with GLM/logistic regression using net reclassification improvement analysis and the five best performing algorithms were combined in an ensemble model using stacking. Results All models performed above chance level. We found Gradient Boosting to be the best performing algorithm (AUC = 0.774) and K-Nearest Neighbors to be the least performing (AUC = 0.702). The performance of GLM/logistic regression (AUC = 0.76) was slightly above average among the tested algorithms. In a Net Reclassification Improvement analysis Gradient Boosting outperformed GLM/logistic regression by 2.9% and K-Nearest Neighbors by 11.3%. GLM/logistic regression outperformed K-Nearest Neighbors by 8.7%. Nine of the top-10 most important predictor variables were related to previous mental health care use. Conclusions Gradient Boosting led to the highest predictive accuracy and AUC while GLM/logistic regression performed average among the tested algorithms. Although statistically significant, the magnitude of the differences between the machine learning algorithms was in most cases modest. The results show that a predictive accuracy similar to the best performing model can be achieved when combining multiple algorithms in an ensemble model.

scholarly journals MODIS-FIRMS and ground-truthing based wildfire likelihood mapping of Sikkim Himalaya using machine learning algorithms.

2021 ◽  
Author(s):  
Polash Banerjee
Keyword(s):  
Machine Learning ◽  
Machine Learning Algorithms ◽  
Tree Cover ◽  
Anthropogenic Factors ◽  
Gradient Boosting ◽  
Support Vector ◽  
Learning Methods ◽  
Sikkim Himalaya ◽  
Environmental Features ◽  
Machine Learning Methods

Abstract Wildfires in limited extent and intensity can be a boon for the forest ecosystem. However, recent episodes of wildfires of 2019 in Australia and Brazil are sad reminders of their heavy ecological and economical costs. Understanding the role of environmental factors in the likelihood of wildfires in a spatial context would be instrumental in mitigating it. In this study, 14 environmental features encompassing meteorological, topographical, ecological, in situ and anthropogenic factors have been considered for preparing the wildfire likelihood map of Sikkim Himalaya. A comparative study on the efficiency of machine learning methods like Generalized Linear Model (GLM), Support Vector Machine (SVM), Random Forest (RF) and Gradient Boosting Model (GBM) has been performed to identify the best performing algorithm in wildfire prediction. The study indicates that all the machine learning methods are good at predicting wildfires. However, RF has outperformed, followed by GBM in the prediction. Also, environmental features like average temperature, average wind speed, proximity to roadways and tree cover percentage are the most important determinants of wildfires in Sikkim Himalaya. This study can be considered as a decision support tool for preparedness, efficient resource allocation and sensitization of people towards mitigation of wildfires in Sikkim.

Sign in / Sign up

Export Citation Format

Share Document