scholarly journals Lung ultrasound for the diagnosis of cystic fibrosis pulmonary exacerbation

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Maryam Hassanzad ◽  
Arda Kiani ◽  
Atefeh Abedini ◽  
Hoseinali Ghaffaripour ◽  
Habib Emami ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Predictive Value ◽  
Diagnostic Performance ◽  
Lung Ultrasound ◽  
Characteristic Curve ◽  
Cross Sectional Study ◽  
Pulmonary Exacerbation ◽  
High Resolution Computed Tomography ◽  
Cross Sectional ◽  
Pleural Thickening

Abstract Background High-resolution computed tomography (HRCT) is the gold standard for the evaluation of cystic fibrosis (CF) lung disease; however, lung ultrasound (LUS) is being increasingly used for the assessment of lung in these patients due to its lower cost, availability, and lack of irradiation. We aimed to determine the diagnostic performance of LUS for the evaluation of CF pulmonary exacerbation. Methods This cross-sectional study included patients with CF pulmonary exacerbation admitted to Masih Daneshvari Hospital, Tehran, Iran, from March 21, 2020 to March 20, 2021. Age, gender, and body mass index (BMI) of the patients were recorded. All patients underwent chest X-ray (CXR), HRCT, and LUS on admission. Pleural thickening, atelectasis, air bronchogram, B-line, and consolidation were noted in LUS and then compared with the corresponding findings in CXR and HRCT. Taking HRCT findings as reference, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy (DA) of LUS and CXR for the detection of each pulmonary abnormality were determined. Results Of the 30 patients included in this study, with a mean age of 19.62 ± 5.53 years, 14 (46.7%) were male. Of the 15 patients aged 2–20 years, BMI was below the 5th percentile in 10 (66.7%), within the 5–10 percentiles in 1 (6.7%), 10–25 percentiles in 3 (20%), and 25-50 percentiles in 1 (6.7%). The mean BMI for 15 patients > 20 years was 18.03 ± 2.53 kg/m2. LUS had better diagnostic performance compared to CXR for the detection of air bronchogram, consolidation, and pleural thickening (area under the receiver operating characteristic curve [AUROC]: 0.966 vs. 0.483, 0.900 vs. 0.575, and 0.656 vs. 0.531, respectively). Also, LUS was 100% and 96.7% specific for the diagnosis of pleural effusion and atelectasis, respectively. Conclusions LUS appears to be superior to CXR and comparable with HRCT for the evaluation of CF pulmonary exacerbation, especially in terms of air bronchogram and consolidation detection. LUS can be used to lengthen the HRCT evaluation intervals in this regard or utilized along with HRCT for better evaluation of CF pulmonary exacerbation.

Diagnostic Accuracy of HRCT Chest in Detection of Covid-19 Infection Taking PCR as Gold Standard

2021 ◽  
Vol 15 (6) ◽  
pp. 1679-1681
Author(s):  
Afaque Ali ◽  
Majid Shaikh ◽  
Ahsanullah . ◽  
Adeel Ahmed ◽  
Abid Ali Sahito ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Diagnostic Accuracy ◽  
Predictive Value ◽  
Gold Standard ◽  
Cross Sectional Study ◽  
Radiology Department ◽  
High Resolution Computed Tomography ◽  
Cross Sectional ◽  
Head Of Department

Objective: To determine the diagnostic accuracy of High-resolution computed tomography (HRCT) chest in detection of covid-19 infection taking PCR as gold standard. Study Design: Cross-sectional study Setting: Radiology department of Tabba Hospital, Karachi. Duration: From March 2019 to September 2020 Material and Methods: All the clinically suspected patients of covid-19, of any age, both genders and those referred to radiology for High-resolution computed tomography (HRCT) chest to detect the covid-19 infection were included. After two days, patients’ PCR reports were collected from the ward, after taking informed consent and permission from head of department. The diagnostic accuracy of HRCT was established with respect to sensitivity, PPV, NPV, and specificity by taking PCR as gold standard. All the information was collected via study proforma. Results: Total 70 patients suspected for COVID-19 were studied, and the patients’ mean age was 58.23±9.52 years. Males were in majority 54(77.1%). As per HRCT findings, COVID-19 infection was positive in 46 patients, however, 48 patients were detected positive for COVID-19 infection as per PCR findings. In the detection of COVID-19 infection, HRCT chest showed sensitivity of 91%, specificity of 90%, PPV of 83%, NPV of 84% and diagnostic accuracy of 94%; by taking PCR as gold standard. Conclusion: High-resolution computed tomography (HRCT) is a reliable diagnostic approach in promptly detecting the COVID-19; with 91% sensitivity, 90% specificity, 83% positive predictive value, 84% negative predictive value and 94% diagnostic accuracy. Keywords: Accuracy, HRCT, COVID-19

scholarly journals Anthropometric parameters’ cut-off points and predictive value for metabolic syndrome in women from Cartagena, Colombia

2014 ◽  
Vol 56 (2) ◽  
pp. 146 ◽  
Author(s):  
Gustavo José Mora-García ◽  
Doris Gómez-Camargo ◽  
Enrique Mazenett ◽  
Ángelo Alario ◽  
Álvaro Fortich ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Latin American ◽  
Predictive Value ◽  
Characteristic Curve ◽  
Cross Sectional Study ◽  
Adult Women ◽  
Anthropometric Parameters ◽  
Cross Sectional ◽  
Body Adiposity ◽  
Cartagena De Indias

Objective. To estimate anthropometric parameters’ (APs) cut-off points and association for metabolic syndrome (MetS). Materials and methods. A cross-sectional study was car­ried out with a total of 434 adult women from Cartagena de Indias, Colombia, in 2012. APs measured were waist circumference (WC), body mass index (BMI), body adiposity index (BAI), waist-hip ratio (WHR) and waist-height ratio (WHtR). Cut-off points were estimated by a receiver op­erating characteristic curve (ROC). Logistic regression was applied to estimate possible associations. Results. Cut-off points for WC, BMI, BAI, WHR and WHtR were 85 cm, 28 kg/m2, 39%, 0.80 and 56, respectively. Only WHtR was associated to MetS (OR=1.11, CI95% [1.07-1.15]). Conclu­sion. WC cut-off point was higher than those proposed for Latin-American women by the Joint Interim Statement (JIS). WHtR had a low predictive value for MetS.

Ratio of height to thyromental distance: a comparison with Mallampati and Upper lip Bite test for predicting difficult intubation in Pakistani population

2021 ◽  
pp. 1-15
Author(s):  
Saman Tauheed Ali ◽  
Khalid Samad ◽  
Syed Amir Raza ◽  
Muhammad Qamarul Hoda
Keyword(s):  
Predictive Value ◽  
Characteristic Curve ◽  
Cross Sectional Study ◽  
Difficult Laryngoscopy ◽  
University Hospital ◽  
Upper Lip ◽  
Cross Sectional ◽  
Elective Surgical Procedures ◽  
Lehane Grade ◽  
Sensitivity Specificity

Objectives: We conducted this study to compare the accuracy of three diagnostic tests; ratio of height to thyromental distance (RHTMD), Modified Mallampati Test (MMT) and Upper Lip Bite Test (ULBT) in predicting difficult laryngoscopy using Cormack and Lehane grade as gold standard.Methods: This study was conducted in Aga Khan University Hospital, Karachi. Based on calculated sample size, 383 patients who required endotracheal intubation for elective surgical procedures were enrolled with consecutive sampling techniques during August 2014 to August 2015 for this cross-sectional study. Primary investigator used RHTMD, ULBT, and MMT for assessing the airway and correlated with laryngoscopic view.Results: A total of 383 patients were incorporated in this research, out of which 59(15.4%) classified as difficult laryngoscopy based on Cormack and Lehane (CL) grading. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of RHTMD (84.7%, 90.1%, 60.9%, 97%, 89.3%) and ULBT (83.1%, 89.2%, 58.3%, 96.7%, 88.3%) values were highest as compared to MMT (30.5%, 84.3%, 26.1%, 86.9%, 79.9%). The area under a receiver-operating characteristic curve (AUC of ROC curve) for ULBT and RHTMD was significantly more than for MMT (P<0.01). RHTMD and ULBT both are acceptable alternatives for prediction of difficult laryngoscopy as a simple, single bed-side test. Continuous...

scholarly journals Association and Predictive Value Analysis for Resting Heart Rate and Diabetes Mellitus on Cardiovascular Autonomic Neuropathy in General Population

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Zi-Hui Tang ◽  
Fangfang Zeng ◽  
Zhongtao Li ◽  
Linuo Zhou
Keyword(s):  
General Population ◽  
Predictive Value ◽  
Large Scale ◽  
Reference Group ◽  
Characteristic Curve ◽  
Predictive Performance ◽  
Population Based ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Value Analysis

Background.The purpose of this study was to evaluate the predictive value of DM and resting HR on CAN in a large sample derived from a Chinese population.Materials and Methods.We conducted a large-scale, population-based, cross-sectional study to explore the relationships of CAN with DM and resting HR. A total of 387 subjects were diagnosed with CAN in our dataset. The associations of CAN with DM and resting HR were assessed by a multivariate logistic regression (MLR) analysis (using subjects without CAN as a reference group) after controlling for potential confounding factors. The area under the receiver-operating characteristic curve (AUC) was used to evaluate the predictive performance of resting HR and DM.Results.A tendency toward increased CAN prevalence with increasing resting HR was reported (Pfor trend<0.001). MLR analysis showed that DM and resting HR were very significantly and independently associated with CAN (P<0.001for both). Resting HR alone or combined with DM (DM-HR) both strongly predicted CAN (AUC = 0.719, 95% CI 0.690–0.748 for resting HR and AUC = 0.738, 95% CI 0.710–0.766 for DM-HR).Conclusion.Our findings signify that resting HR and DM-HR have a high value in predicting CAN in the general population.

scholarly journals Bedside lung ultrasonography by emergency department residents as an aid for identifying heart failure in patients with acute dyspnea after a 2-h training course

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Mohamed Amine Msolli ◽  
◽  
Adel Sekma ◽  
Maryem Ben Marzouk ◽  
Wael Chaabane ◽  
...  
Keyword(s):  
Heart Failure ◽  
Emergency Department ◽  
Predictive Value ◽  
Lung Ultrasound ◽  
Characteristic Curve ◽  
Trial Registration ◽  
Ordinal Scale ◽  
Acute Dyspnea ◽  
Cross Sectional ◽  
B Lines

Abstract Background Ultrasonographic B-lines have recently emerged as a bedside imaging tool for the differential diagnosis of acute dyspnea in the Emergency Department (ED). However, despite its simplicity, LUS has not fully penetrated emergency department. This study aimed to assess the accuracy and reproducibility of ultrasonographic B-lines performed by emergency medicine (EM) residents for the diagnosis of congestive heart failure (CHF) in patients admitted to ED for acute dyspnea. Patients and methods This is a cross-sectional prospective study conducted between January 2016 and October 2017 including patients aged over 18 years admitted to ED for acute dyspnea. At admission, two consecutive bedside LUS study were performed by a pair of EM residents who received a 2-h course for recognition of sonographic B-lines to determine independently B-lines score and B-profile pattern. All participating sonographers were blinded to patients’ clinical data. B-lines score ≥ 15 or a B-profile pattern was considered as suggestive of CHF. The final leading diagnosis was assessed by two expert sonographers, who were blinded to the residents’ interpretations, based on clinical findings, chest X-ray, brain natriuretic peptide, cardiac and lung ultrasound testing. Accuracy and agreement of B-lines score and B-profile pattern were calculated. Results We included 700 patients with a mean age of 68 ± 12.6 years and a sex ratio (M/F) of 1.43. The diagnosis of CHF was recorded in 371 patients (53%). The diagnostic performance of B-lines score at a cut-off 15 and B-profile pattern was, respectively, 88% and 82.5% for sensitivity, 75% and 84% for specificity, 80% and 85% for positive predictive value, 84% and 81% for negative predictive value. The area under receiver operating characteristic curve was 0.86 [0.83–0.89] and 0.83 [0.80–0.86], respectively, for B-lines score and B-profile pattern. There was an excellent agreement between residents for the diagnosis of CHF using both scores (kappa = 0.81 and 0.85, respectively, for ordinal scale B-lines score and B-profile pattern). Conclusion Lung ultrasound B-lines assessment has a good accuracy and an excellent reproducibility in the diagnosis of CHF in the hand of EM residents following a short training program. Trial registration Name of the registry: clinicaltrials.gov; Trial registration number: NCT03717779; Date of registration: October 24, 2018 ‘Retrospectively registered’; URL of trial registry record: clinicaltrials.gov

scholarly journals Gender Differences: Does it affect clinical, radiological and microbiological features in adult non-cystic fibrosis bronchiectasis?

Acta Medica ◽  
2019 ◽  
Vol 50 (2) ◽  
pp. 25-31
Author(s):  
Elif Yelda Niksarlıoğlu
Keyword(s):  
Gender Differences ◽  
Cystic Fibrosis ◽  
Pulmonary Function ◽  
Pulmonary Function Tests ◽  
Severity Index ◽  
Cross Sectional Study ◽  
Smoking History ◽  
High Resolution Computed Tomography ◽  
Cross Sectional ◽  
Group I

Objective: This study aimed to investigate the gender effect on the clinic, radiological, and microbiological features in adult non-cystic fibrosis (CF) bronchiectasis (BR). Material and Methods:This was a cross-sectional study of 217 patients with adult non-CF BR. Patients with a confirmed diagnosis of bronchiectasis with high resolution computed tomography were investigated. Patients were clinically stable in the previous four weeks enrolled in the study. Symptoms, pulmonary function tests, radiological findings, microbiological results, and bronchiectasis severity index (BSI) were recorded. Results: The mean age of patients was 49.7 (15.3) years (range 18-82). Fouty-one percent patients had smoking history. BR patients had a history of pneumonia sequel (47.9%), post-tuberculosis (33.6%) and idiopathic (15.7%). Patients divided in to 2 groups as group I (female, n=122 (56.2%)) and group II (male, n=95 (43.8%)). There were a differences in cough (84.4% vs 71.6%, p=0.029), smoking history (19.7% vs 75.9 %,p=0.001), COPD (4.1% vs 37.9%, p=0.001), diabetes mellitus (21.3% vs 9.5%, p=0.025), depression history(36.1% vs 10.6%, p=0.001), panic disorders (10.7% vs 3.2%, p=0.039), long term oxygen usage (6.6% vs 17.9%,p=0.017). Forty-two percent of male BR patients had post-tuberculosis history, fifty-six female had post-pneumonia history, also. FEV1 and FVC value were higher in man (1.5±0.7 vs 1.9±0.9,p= 0.001; 1.9±0.7 vs 2.7±1.0, p=0.0001 respectively). And also, FEV1/FVC ratio was lower in male (73.8±12.3 vs 67.8±15.3, p=0.01). But, There was no difference between gender and age, dyspnea, heamoptysis, BSI category, radiologic severity using Reiff’s score, microbiological features and BPAP usage. Conclusion: We concluded that gender differences in non-CF BR might be clinically important in our study population. It is important to consider the gender differences might be effect symptoms, comorbidity, and pulmonary function test results to non-CF BR patients.

Diagnostic performance of midupper arm circumference for detecting severe wasting among infants aged 1–6 months in Ethiopia

2020 ◽  
Vol 113 (1) ◽  
pp. 55-62
Author(s):  
Beshada R Jima ◽  
Hamid Y Hassen ◽  
Yalemwork Getnet ◽  
Paluku Bahwere ◽  
Seifu H Gebreyesus
Keyword(s):  
Predictive Value ◽  
Diagnostic Performance ◽  
Operating Characteristic ◽  
Cross Sectional Study ◽  
Child Growth ◽  
Youden Index ◽  
Cross Sectional ◽  
Growth Standards ◽  
Arm Circumference ◽  
Sensitivity Specificity

ABSTRACT Background Midupper arm circumference (MUAC) is used as an independent diagnostic tool to detect wasting in children aged 6–59 mo. However, little is known about the diagnostic performance of MUAC for detecting wasting among infants aged 1–6 mo. Objective The objective of this study was to evaluate the diagnostic performance of MUAC in detecting severe wasting in infants aged 1–6 mo. Methods We conducted a facility-based cross-sectional study among 467 hospitalized infants aged 1–6 mo in Ethiopia. Severe wasting was defined as having a weight for length z score (WLZ) below the cutoff value of −3 SDs from the median as per the WHO 2006 child growth standards. Receiver operating characteristic (ROC) analysis along with the calibration test was used to test the discriminatory performance of MUAC. Furthermore, we calculated the sensitivity, specificity, positive predictive value, and negative predictive value for the proposed optimal cutoffs. Results The median age, MUAC, and WLZ were 100 d (IQR: 69–145 d), 119 mm (IQR: 103–130 mm), and −1.27 (IQR: −2.66 to 0.34), respectively. The prevalence of severe and moderate wasting was n = 101 (21.6%) and n = 61 (13.0%), respectively. The MUAC area under the ROC curve accuracy level in identifying severe wasting was 0.86 (95% CI: 0.82, 0.89). The optimal MUAC cutoff of ≤112 mm yielded the highest Youden index of 0.61, with a sensitivity of 85.1% (95% CI: 76.7%, 91.4%) and a specificity of 76.0% (95% CI: 71.2%, 80.2%). Conclusions A MUAC cutoff of ≤112 mm performed well in detecting severe wasting among infants aged 1–6 mo. Further research is needed to evaluate the performance of MUAC for detecting wasting at community level and for predicting mortality among infants aged &lt;6 mo.

scholarly journals Association between Hemoglobin Glycation Index and NAFLD in Chinese Nondiabetic Individuals

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Di-Shuang Hu ◽  
Sheng-Hao Zhu ◽  
Xu Li ◽  
Qin-Fen Chen ◽  
Chun-Jing Lin ◽  
...  
Keyword(s):  
Risk Score ◽  
Predictive Value ◽  
Characteristic Curve ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Receiver Operator Characteristic Curve ◽  
Abdominal Ultrasonography ◽  
Cross Sectional ◽  
Nonalcoholic Fatty Liver ◽  
Hemoglobin Glycation

Purpose. Limited studies have preliminarily identified a positive association between nonalcoholic fatty liver disease (NAFLD) and hemoglobin glycation index (HGI). However, this association has not been fully established. We aim to investigate the association between NAFLD and HGI in Chinese nondiabetic individuals and to construct a risk score based on HGI to predict a person’s risk of NAFLD. Methods. After strict exclusion criteria, 5,903 individuals were included in this retrospective cross-sectional study. We randomly selected 1,967 subjects in the enrollment to obtain an equation of linear regression, which was used to calculate predicted HbA1c and drive HGI. The other subjects were classified into four categories according to HGI level (≤−0.22, −0.21∼0.02, 0.03∼0.28, and ≥0.29). All subjects retrospectively reviewed the baseline characteristics, laboratory examinations, and abdominal ultrasonography. Results. The prevalence of NAFLD in this population was 20.7%, which increases along with the growth of HGI levels (P<0.001). Adjusted to multiple factors, this trend still remained significant (OR: 1.172 (95% CI, 1.074–1.279)). The combined NAFLD risk score based on HGI resulted in an area under the receiver operator characteristic curve (AUROC) of 0.85 provided sensitivity, specificity, positive predictive value, and a negative predictive value for NAFLD of 84.4%, 71.3%, 65.0%, and 88.0%, respectively. Conclusions. NAFLD is independently associated with HGI levels in Chinese nondiabetic individuals. And, NAFLD risk score may be used as one of the risk predictors of NAFLD in nondiabetic population.

scholarly journals Validation and reproducibility of the lung function questionnaire (LFQ) for the diagnosis of COPD in Colombia

Pneumologia ◽  
2020 ◽  
Vol 69 (1) ◽  
pp. 37-46
Author(s):  
Alirio Rodrigo Bastidas Goyes ◽  
Andrés Felipe Barragán Amado ◽  
Maria Mónica Martinez ◽  
Natalia Pinzón Villamil ◽  
Arsanios Martin Daniel
Keyword(s):  
Lung Function ◽  
Predictive Value ◽  
Characteristic Curve ◽  
Cross Sectional Study ◽  
Chronic Obstructive ◽  
Clinical Prediction ◽  
Validity And Reliability ◽  
Cross Sectional ◽  
Time Points ◽  
Dichotomous Outcome

AbstractIntroductionThe development of clinical prediction scales and their use can reduce under-diagnosis and increase early detection of chronic obstructive pulmonary disease (COPD). The performance of clinical prediction scales in Colombia is unknown. The objective of this study is to evaluate the validity and reproducibility of the lung function questionnaire (LFQ) in Colombia.MethodA cross-sectional study was performed, with analysis of diagnostic validity and reliability in people over 40 years of age who underwent a spirometry test. The LFQ questionnaire was applied. To assess reproducibility, the test was carried out at two time points: first at the initial consultation; and then 1 day to 1 week after the previous application. Spirometry was performed immediately after the initial questionnaire, meeting the American Thoracic Society criteria.ResultsAmong the 1996 subjects included in the analysis, the average age was 65 years (SD: 11.97 years), prevalence of COPD was 21.3%, the intra-class correlation coefficient between the two time points was 0.844 (95% CI: 0.863–0.901) (p < 0.001), and kappa was 0.797 for the dichotomous outcome ≤18 COPD risk points (p < 0.001), validity analysis using the area under the receiver operating characteristic curve for the population evaluated was 0.715 (95% CI: 0.685–0.745); the dichotomous outcome of the questionnaire ≤18 points was as follows: sensitivity – 91.18% (95% CI: 88.0–94.3); specificity – 32.41% (95% CI: 29.8–35.0); positive predictive value – 26.7% (95% CI: 24.1–29.3); negative predictive value – 93.15% (95% CI: 90.7–95.6); likelihood ratio (LR) +: 1.34 (95% CI: 1.28–1.42), LR– 0.27 (95% CI: 0.19–0.39); number needed to diagnose: 4; number needed to misdiagnose: 2 (p < 0.001).ConclusionThe LFQ questionnaire has good performance for the diagnosis of COPD, especially in populations without previous respiratory symptoms or usual risk factors, optimising the use of spirometry to increase its detection.

scholarly journals Candiduria in hospitalized patients: an investigation with the Sysmex UF-1000i urine analyzer

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e6935 ◽  
Author(s):  
Zhengxin He ◽  
Yanli Liu ◽  
Tingting Wang ◽  
Yan Cheng ◽  
Jing Chen ◽  
...  
Keyword(s):  
Risk Factor ◽  
Predictive Value ◽  
Characteristic Curve ◽  
Target Population ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Hospitalized Patients ◽  
Cross Sectional ◽  
Seriously Ill Patients ◽  
Sensitivity Specificity

Background Candiduria is common in hospitalized patients. Its management is limited because of inadequate understanding. Previous epidemiological studies based on culture assay have been limited to small study populations. Therefore, data collected by automated systems from a large target population are necessary for more comprehensive understanding of candiduria in hospitalized patients. Methods To determine the performance of the Sysmex UF-1000i in detecting candiduria, a cross-sectional study was designed and conducted. A total of 203 yeast-like cell (YLC)-positive and 127 negative samples were randomly chosen and subjected to microbiologic analysis. The receiver operating characteristic curve (ROC) was used to evaluate the ability of YLC counts as measured by the Sysmex UF1000i to predict candiduria. Urinalysis data from 31,648 hospitalized patients were retrospectively investigated, and statistical analysis was applied to the data collected. Results Using a cutoff value of 84.6 YLCs/µL, the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the yeast like cell (YLC) counts to predict candiduria were 61.7%, 84.1%, 88.6% and 66.3%, respectively. C. glabrata (33.6%) and C. tropicalis (31.4%) were more prevalent than C. albicans (24.3%) in the present study. Of the investigated hospitalized patients, 509 (1.61%) were considered candiduria-positive. Age, gender and basic condition were associated with candiduria in hospitalized patients. In the ICU setting, urinary catheterization appeared to be the only independent risk factor contributing to candiduria according to our investigation. Although antibiotic therapy has been reported to be a very important risk factor, we could not confirm its significance in ICU candiduria patients because of excessive antibiotic usage in our hospital. Conclusions The YLC measured by Sysmex UF-1000i is a practical and convenient tool for clinical candiduria screening prior to microbiologic culture. Candiduria is common in hospitalized patients, and its incidence varies according to age, gender and the wards where it is isolated. Candiduria had no direct connection with mortality but might be considered a marker of seriously ill patients who need particular attention in the clinic.

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