scholarly journals The influence of prenatal exposure to trans-fatty acids for development of childhood haematopoietic neoplasms (EnTrance): a natural societal experiment and a case-control study

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Ina Olmer Specht ◽  
Inge Huybrechts ◽  
Peder Frederiksen ◽  
Eva Steliarova-Foucher ◽  
Veronique Chajes ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Prenatal Exposure ◽  
Trans Fatty Acids ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Adipose Tissue Trans Fatty Acids and Risk of Coronary Artery Disease: A Case-Control Study

2008 ◽  
Vol 52 (1) ◽  
pp. 24-28 ◽  
Author(s):  
Faranak Ghahremanpour ◽  
Mohsen Firoozrai ◽  
Masoud Darabi ◽  
Abbas Zavarei ◽  
Ahmad Mohebbi
Keyword(s):  
Coronary Artery Disease ◽  
Fatty Acids ◽  
Adipose Tissue ◽  
Coronary Artery ◽  
Trans Fatty Acids ◽  
Case Control Study ◽  
Case Control ◽  
Artery Disease ◽  
Control Study

Association of decreased spermatozoa omega-3 fatty acid levels and increased oxidative DNA damage with varicocele in infertile men: a case control study

2016 ◽  
Vol 28 (5) ◽  
pp. 648 ◽  
Author(s):  
Li-Xin Tang ◽  
Dong-Juan Yuan ◽  
Qi-Ling Wang ◽  
Fang Jiang ◽  
Jian Guo ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Dna Damage ◽  
Oxidative Dna Damage ◽  
Case Control Study ◽  
Cell Structure ◽  
Case Control ◽  
Omega 3 ◽  
Infertile Men ◽  
Omega 6 ◽  
Control Study

Varicocele is commonly associated with male infertility because it impairs normal sperm morphology and activity. Polyunsaturated fatty acids (PUFA) are important determinants of sperm cell structure and function, but their relationship with varicocele remains unclear. The aim of the present study was to investigate the PUFA composition in spermatozoa of infertile men with varicocele and to evaluate the potential relationship between PUFA and varicocele. This case control study recruited 92 infertile men with varicocele, 99 infertile men without varicocele and 95 fertile male control subjects. Semen morphology and activity parameters were assessed and seminal plasma 8-hydroxy-2-deoxyguanosine (8-OHdG) content was determined by ELISA. Sperm concentrations of omega-3 and omega-6 fatty acids were measured by gas chromatography. Infertile men with varicocele had lower concentrations of omega-3 PUFA, higher omega-6 : omega-3 PUFA ratios and greater oxidative DNA damage in spermatozoa compared with infertile men without varicocele and normal subjects. The degree of varicocele and DNA damage was associated with decreased omega-3 PUFA concentrations and semen quality in infertile men with varicocele. The findings suggest that omega-3 PUFA deficiency could be implicated in varicocele-associated infertility, and highlight the need for intervention trials to test the usefulness of omega-3 supplementation in reducing sperm abnormalities in infertile men with varicocele.

Longchain serum fatty acids and risk of thyroid cancer: A population-based case-control study in Norway

1994 ◽  
Vol 5 (5) ◽  
pp. 433-439 ◽  
Author(s):  
Jens P. Berg ◽  
Eystein Glattre ◽  
Tor Haldorsen ◽  
Arne T. Høstmark ◽  
Ida G. Bay ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Thyroid Cancer ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Control Study ◽  
Serum Fatty Acids

Characterising phospholipids and free fatty acids in patients with schizophrenia: A case-control study

2020 ◽  
pp. 1-14 ◽  
Author(s):  
Dongfang Wang ◽  
Xiaoyu Sun ◽  
Michel Maziade ◽  
Wei Mao ◽  
Chuanbo Zhang ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Free Fatty Acids ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Role of SNPs of CPTIA and CROT genes in the carnitine-shuttle in coronary artery disease: a case-control study

2019 ◽  
Vol 44 (6) ◽  
pp. 822-830
Author(s):  
Aslihan Demircan ◽  
Ender Coskunpinar ◽  
Deniz Kanca ◽  
Gulcin Ozkara ◽  
Fatih Yanar ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Fatty Acids ◽  
Case Control Study ◽  
Threshold Value ◽  
Case Control ◽  
Long Chain Fatty Acids ◽  
Artery Disease ◽  
Control Study ◽  
Long Chain

Abstract Objective Fatty acid β-oxidation defects can lead to difficulties at covering energy requirement of heart. The carnitine-shuttle is responsible for the transfering of long-chain fatty acids from the internal mitochondrial membrane. The role of genetic variants of the enzymes in the carnitine shuttle in coronary artery disease (CAD) has not been studied. Therefore, we performed a case-control study investigating the possible relation between the CPTIA-rs3019613 and CROT-rs2214930 gene variations located carnitine shuttle and CAD risk. Materials and methods Study groups were comprised of 96 CAD patients and 85 controls. CPTIA-rs3019613 G > A and CROT-rs2214930 T > C polymorphisms were determined by real-time-PCR. Results The CROT-rs2214930-CC genotype was found to be associated with decreased HDL-cholesterol (HDL-C) in controls (p = 0.029). In patients with CPTIA-rs3019613-A allele, body mass index (BMI) (p = 0.016) and BMI threshold-value (p = 0.030) were found be higher compared to those with GG-genotype, while HDL-C threshold-value (HDL-C ≤ 0.90 mmol/L) was found to be lower (p = 0.015). Regression analysis confirmed CPTIA-rs3019613-A allele has a significant relationship with decreased HDL-C (p = 0.009) in patients. Conclusion Our study indicated that the polymorphisms of the CROT and CPTIA genes related to β-oxidation of long-chain fatty acids had an important effect on serum HDL-C levels and may be a potential risk for CAD.

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