Empirically derived dietary patterns and constipation among a middle-aged population from China, 2016–2018

Abstract Background The association of dietary patterns with constipation is not well established, particularly in Chinese population. Therefore, the present study aimed to determine the relationship between dietary patterns and the risk of constipation in a middle-aged Chinese population. Methods A total of 2267 participants aged 45–59 years were recruited in Hangzhou city, the capital of Zhejiang Province, east China from August 2016 to October 2018. Dietary intake was estimated using a semi-quantitative food frequency questionnaire (FFQ) containing 138 food items. Constipation was defined using the Rome II criteria. Multivariate logistic regression was used to examine the association between dietary patterns and the risk of constipation. Results Three major dietary patterns were extracted by factor analysis and labeled as the traditional southern Chinese, Western and grains-vegetables patterns. The prevalence of constipation in our study population was 13.28%. Compared with the participants in the lowest quartile, the participants in the highest quartile of the traditional southern Chinese pattern were associated with reduced odds of constipation (odd ratios (OR) = 0.79; 95%confidence interval (CI): 0.626–0.981; P < 0.05), after adjusting for confounding variables. In contrast, we found no significant associations between the Western and grains-vegetables patterns and the risk of constipation (P > 0.05). Conclusions Our study demonstrated that the traditional southern Chinese pattern was associated with a reduced risk of constipation. Further longitudinal studies are needed to confirm our findings.

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Association Between Dietary Patterns and Prediabetes Risk in A Middle-Aged Chinese Population

10.21203/rs.3.rs-29462/v1 ◽

2020 ◽

Author(s):

Xiao-Ming Shen ◽

Yi-Qian Huang ◽

Xiao-Yan Zhang ◽

Xiao-Qing Tong ◽

Pei-Fen Zheng ◽

...

Keyword(s):

Dietary Patterns ◽

Chinese Population ◽

Regression Models ◽

Multivariate Logistic Regression ◽

Middle Aged ◽

Food Frequency ◽

Logistic Regression Models ◽

Southern Chinese ◽

Bottom Quartile ◽

Confounding Variables

Abstract Background: Information regarding dietary patterns associated with prediabetes in the Chinese population is lacking. The objective of the present study was to explore the association between major dietary patterns and risk of prediabetes in a middle-aged Chinese population. Methods: A total of 1761 participants (aged 45 to 59 years) were recruited in Hangzhou city, the capital of Zhejiang Province, China from June 2015 to December 2016. Dietary information was obtained by interview using a 138-item, validated semi-quantitative food frequency questionnaire(SQFFQ). Multivariate logistic regression models were used to analyze the association between dietary patterns and the risk of prediabetes with adjustment of potential confounding variables. Results: Three dietary patterns were ascertained by factor analysis and labeled as traditional southern Chinese, Western, and grains-vegetables patterns. After controlling of the potential confounders, participants in the top quartile of the Western pattern scores had greater odds ratio(OR) for prediabetes (OR=1.54; 95% confidence interval(CI):1.068-2.059; P =0.025) than did those in the bottom quartile. Compared with those in the bottom quartile, participants in the top quartile of the grains-vegetables pattern scores had a lower OR for prediabetes(OR=0.83; 95% CI:0.747-0.965; P =0.03). Besides, no statistically significant association was observed in the association between the traditional southern Chinese pattern and prediabetes risk ( P >0.05). Conclusions: The findings of this study showed that the Western pattern was associated with a higher risk, and the grains-vegetables pattern was associated with a lower risk of prediabetes. Future prospective studies are required to validate our findings.

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Association between dietary patterns and prediabetes risk in a middle-aged Chinese population

10.21203/rs.3.rs-29462/v2 ◽

2020 ◽

Author(s):

Xiao-Ming Shen ◽

Yi-Qian Huang ◽

Xiao-Yan Zhang ◽

Xiao-Qing Tong ◽

Pei-Fen Zheng ◽

...

Keyword(s):

Dietary Patterns ◽

Chinese Population ◽

Regression Models ◽

Multivariate Logistic Regression ◽

Middle Aged ◽

Food Frequency ◽

Logistic Regression Models ◽

Southern Chinese ◽

Bottom Quartile ◽

Confounding Variables

Abstract Background: Information regarding dietary patterns associated with prediabetes in the Chinese population is lacking. The objective of the present study was to explore the association between major dietary patterns and the risk of prediabetes in a middle-aged Chinese population. Methods: A total of 1761 participants (aged 45 to 59 years) were recruited in Hangzhou city, the capital of Zhejiang Province, China from June 2015 to December 2016. Dietary information was obtained by interview using a 138-item, validated semi-quantitative food frequency questionnaire(SQFFQ). Multivariate logistic regression models were used to analyze the associations between dietary patterns and the risk of prediabetes with adjustment of potential confounding variables. Results:Three dietary patterns were ascertained by factor analysis and labeled as traditional southern Chinese, Western, and grains-vegetables patterns. After controlling of the potential confounders, participants in the top quartile of the Western pattern scores had greater odds ratio(OR) for prediabetes (OR=1.54; 95% confidence interval(CI):1.068-2.059; P=0.025) than did those in the bottom quartile. Compared with those in the bottom quartile, participants in the top quartile of the grains-vegetables pattern scores had a lower OR for prediabetes(OR=0.83; 95% CI:0.747-0.965; P=0.03). Besides, no statistically significant association was observed in the association between the traditional southern Chinese pattern and prediabetes risk (P>0.05). Conclusions:The findings of this study showed that the Western pattern was associated with higher risk, and the grains-vegetables pattern was associated with lower risk of prediabetes. Future prospective studies are required to validate our findings.

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Association between Dietary Patterns and Glycemic Control in a Middle-aged Chinese Population

10.21203/rs.3.rs-190122/v1 ◽

2021 ◽

Author(s):

Xiao-Ming Shen ◽

Long Shu ◽

Yi-Qian Huang ◽

Xiao-Yan Zhang ◽

Pei-Fen Zheng ◽

...

Keyword(s):

Glycemic Control ◽

Dietary Patterns ◽

Regression Models ◽

Principal Component ◽

Chinese Adults ◽

Food Frequency ◽

Principal Component Method ◽

Logistic Regression Models ◽

Southern Chinese ◽

The Relationship

Abstract Background: Despite decades of research, data on the relationship between dietary patterns and glycemic control(hemoglobin(Hb)A1c<7%) in China are sparse. The objective of this study was to ascertain the association between different dietary patterns and glycemic control in a large group of Chinese adults aged between 45 and 59 years.Methods: A total of 1739 subjects aged 45-59 years from Hangzhou were included in the analysis. Information on dietary intake was collected by well-trained interviewers using a validated food frequency questionnaire(FFQ). Factor analysis with principal component method was applied to ascertain the main dietary patterns, and the associations between dietary patterns and glycemic control were determined using multivariable logistic regression models. Poor glycemic control was defined as HbA1c≥7.0.Results:Three dietary patterns were ascertained and labeled as traditional southern Chinese, Western, and grains-vegetables patterns. After controlling of the possible confounders, participants in the highest quartile of Western pattern scores had greater odds ratio(OR) for HbA1c≥7.0(OR=1.05; 95% confidence interval(CI):1.000-1.095; P=0.048) than did those in the lowest quartile. Compared with those in the lowest quartile of grains-vegetables pattern, participants in the highest quartile had lower OR for HbA1c≥7.0(OR=0.82; 95% CI:0.720-0.949; P=0.038). Besides, no significant relationship between the traditional southern Chinese pattern and HbA1c≥7.0 was observed(P>0.05). Conclusions:This study indicated that the Western pattern was associated with a higher risk, and the grains-vegetables pattern was associated with a lower risk for HbA1c≥7.0. Future prospective studies are needed to confirm our findings.

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Association between dietary patterns and chronic kidney disease in a middle-aged Chinese population

Public Health Nutrition ◽

10.1017/s1368980019002805 ◽

2019 ◽

Vol 23 (6) ◽

pp. 1058-1066 ◽

Cited By ~ 3

Author(s):

Shan-Shan Xu ◽

Jun Hua ◽

Yi-Qian Huang ◽

Long Shu

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Dietary Patterns ◽

Chinese Population ◽

Eastern China ◽

Health Study ◽

Middle Aged ◽

Cross Sectional ◽

Southern Chinese ◽

Increased Risk

AbstractObjective:To explore the relationship between dietary patterns and risk of chronic kidney disease (CKD) in Chinese adults aged 45–59 years.Design:Dietary data were collected using a semi-quantitative FFQ. Factor analysis was used to identify the major dietary patterns. Logistic regression models were applied to clarify the association between dietary patterns and the risk of CKD.Setting:The present study population was a part of the population-based Nutrition and Health Study performed in the city of Hangzhou, Zhejiang Province, eastern China.Participants:A total of 2437 eligible participants (45–59 years) were enrolled in the present cross-sectional study from June 2015 to December 2016.Results:Three major dietary patterns were identified: ‘traditional southern Chinese’, ‘Western’ and ‘grains–vegetables’ patterns, collectively accounting for 25·6 % of variance in the diet. After adjustment for potential confounders, participants in the highest quartile of the Western pattern had greater odds for CKD (OR = 1·83, 95 % CI 1·21, 2·81; P < 0·05) than those in the lowest quartile. Compared with the lowest quartile of the grains–vegetables pattern, the highest quartile had lower odds for CKD (OR = 0·84, 95 % CI 0·77, 0·93; P < 0·05). In addition, there was no significant association between the traditional southern Chinese pattern and risk of CKD (P > 0·05).Conclusions:Our results suggest that the Western pattern is associated with an increased risk, whereas the grains–vegetables pattern is associated with a reduced risk for CKD. These findings can guide dietary interventions for the prevention of CKD in a middle-aged Chinese population.

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Relationship Between Sleep and Arthritis in a Middle-aged and Older Chinese Population- the China Health and Retirement Longitudinal Study

10.21203/rs.3.rs-253999/v1 ◽

2021 ◽

Author(s):

Chunnan Li ◽

Shang shaomei

Keyword(s):

Logistic Regression ◽

Longitudinal Study ◽

Protective Effect ◽

Sleep Duration ◽

Chinese Population ◽

P Value ◽

Confounding Factors ◽

Middle Aged ◽

Older Chinese ◽

The Relationship

Abstract Objective. To evaluate the relationship between sleep duration, sleep restless and arthritis in middle-aged and older Chinese population. Methods. A total of 4957 middle-aged and elderly people aged 45 years and above from The China Health and Retirement Longitudinal Study (CHARLS) wave 3 were included. Multivariable logistic regression was used to calculate adjusted odds ratios (ORs) and 95 % confidence intervals (CIs) for arthritis. Results. Sleep duration was shown to have a U-shaped association with arthritis after adjusting confounding factors. Compared with <5h sleep duration per night, ORs (95 % CIs) of sleep duration 5-7,7-8 and 8-9 h per night for arthritis were 0.61 (0.52– 0.73, P value <0.001) ,0.47 (0.38-0.58, P value <0.001),0.50 (0.41,0.60, P value <0.001)and 0.50 (0.39–0.64, P value <0.001), respectively. Sleep restless was positively correlated with the prevalence of arthritis. After stratification according to sleep restless status, for those without sleep restless, 8-9 hours duration (OR=0.55, 95 % CI 0.39-0.78,P value=0.001)had the best protective effect on arthritis, while7-8 hours duration (OR=0.45, 95 % CI 0.34-0.60,P value <0.001)was best in people with sleep restless. Conclusion. In middle aged and old Chinese population, sleep duration is U-shaped associated with arthritis, and sleep restless affect the correlation.

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Dietary patterns derived by factor analysis are associated with cognitive function among a middle-aged and elder Chinese population

Psychiatry Research ◽

10.1016/j.psychres.2018.09.004 ◽

2018 ◽

Vol 269 ◽

pp. 640-645 ◽

Cited By ~ 3

Author(s):

Feng-Na Yu ◽

Nai-Qi Hu ◽

Xun-Lan Huang ◽

Yun-Xia Shi ◽

Huan-Zong Zhao ◽

...

Keyword(s):

Factor Analysis ◽

Cognitive Function ◽

Dietary Patterns ◽

Chinese Population ◽

Middle Aged

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The lncRNA SOX2OT rs9839776 C>T Polymorphism Indicates Recurrent Miscarriage Susceptibility in a Southern Chinese Population

Mediators of Inflammation ◽

10.1155/2019/9684703 ◽

2019 ◽

Vol 2019 ◽

pp. 1-6 ◽

Cited By ~ 2

Author(s):

Zhenzhen Fang ◽

Di Che ◽

Shuang Qing ◽

Qingfeng Li ◽

Hui Men ◽

...

Keyword(s):

Chinese Population ◽

Southern China ◽

Recurrent Miscarriage ◽

Age Groups ◽

Migration And Invasion ◽

Multiple Tumor ◽

Southern Chinese ◽

Increased Risk ◽

Healthy Control ◽

The Relationship

Genetic susceptibility may be involved in the onset of recurrent miscarriage. Previous studies have shown that some genetic polymorphisms that regulate cell migration are associated with susceptibility to recurrent miscarriage. The SOX2 overlapping transcript (SOX2OT) may regulate the migration and invasion of multiple tumor cells and is related to susceptibility to various diseases. However, whether lncRNA SOX2OT polymorphisms are related to recurrent miscarriage susceptibility is unclear. Therefore, we investigated the relationship between the lncRNA SOX2OT rs9839776 C>T polymorphism and recurrent miscarriage susceptibility. We recruited 570 subjects with recurrent miscarriage and 578 healthy control subjects from a population in southern China and used the TaqMan method for genotyping. We found a significant association between the rs9839776 CT genotype in the SOX2OT gene and an increased risk for recurrent miscarriage (CT vs CC: adjusted OR=1.357, 95%CI=1.065−1.728, P=0.0134). However, we did not observe any significant associations between the recurrent miscarriage risk and the number of miscarriages in different age groups. In conclusion, our study indicated that the rs9839776 CT genotype may contribute to an increased risk of recurrent miscarriage in the southern Chinese population and that rs9839776 may act as a prognostic biomarker in recurrent miscarriage patients. However, an experiment-based study with a larger sample size should be performed to confirm these results.

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Prevalence and Risk Factors Associated with Prehypertension among Young and Middle-Aged Health Check-Up Population in Guangzhou

Journal of Advances in Medicine Science ◽

10.30564/jams.v4i1.2546 ◽

2021 ◽

Vol 4 (1) ◽

pp. 1

Author(s):

Lulu Yang ◽

Xia Lu ◽

Yao Zhong ◽

Man Lin ◽

Fangfang Lu ◽

...

Keyword(s):

Risk Factors ◽

Logistic Regression ◽

Regression Analysis ◽

Logistic Regression Analysis ◽

Dietary Patterns ◽

Multivariate Logistic Regression Analysis ◽

Health Check ◽

Multivariate Logistic Regression ◽

Middle Aged ◽

Targeted Interventions

Objective: To provide basic information and theories for prehypertension early intervention, a systematic analysis of the epidemic status and risk factors among young and middle-aged was carried out here. Methods: This study relied on the data bank of a health check-up population of a class a tertiary general hospital in Guangdong province in 2015. Total 9540 young and middle-aged adults were enrolled, and 733 people were included to find out the effect with lifestyle in these crowd. Principal Components Analysis (PCA) of Factor (FA) was used to identify dietary patterns. The logistic regression model was used to find the risk factors of prehypertension. Results: Among 9540 young and middle-aged cases, the incidence of prehypertension was 36.6%. Moreover, the average age, proportion of male gender, overweight, FBG (fasting blood glucose), dyslipidemia, and hyperuricemia were significantly higher in the prehypertension group than in the optimal BP group. Multivariate logistic regression analysis indicated that age, total cholesterol, triglycerides, uric acid, body mass index and HR (heart rate) were risk factors, and female was a protective factor for prehypertension. Among 733 cases, the incidence of prehypertension was 35.1%. The proportion of smoking, drinking, physical workers, moderate and severe physical activity, and the intake of meat, dietary energy were significantly higher in the prehypertension group than in the optimal BP group. Dietary patterns included “meat model”, “spice model”, “main vegeTables model” and “high protein model”. Multivariate logistic regression analysis indicated that age, drinking were risk factors for prehypertension, while dietary milk intake, dietary magnesium intake were protective factors. Conclusions: Prehypertension is highly prevalent in Guangzhou. However, education about effective lifestyle modifications as an alcohol limit, increasing the intake of dairy products, and magnesium may intervene in the development of prehypertension. But how to develop targeted interventions for such groups need to be further explored. The present study would lay the theoretical foundation and basic data for the next step.

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Association between dietary patterns and prediabetes risk in a middle-aged Chinese population

Nutrition Journal ◽

10.1186/s12937-020-00593-1 ◽

2020 ◽

Vol 19 (1) ◽

Author(s):

Xiao-Ming Shen ◽

Yi-Qian Huang ◽

Xiao-Yan Zhang ◽

Xiao-Qing Tong ◽

Pei-Fen Zheng ◽

...

Keyword(s):

Dietary Patterns ◽

Chinese Population ◽

Middle Aged

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The relationship between famine exposure during early life and ascending aorta dilatation in adults

British Journal Of Nutrition ◽

10.1017/s0007114521001161 ◽

2021 ◽

pp. 1-29

Author(s):

Yu-qing Huang ◽

Lin Liu ◽

Kenneth Lo ◽

Yu-ling Yu ◽

Chao-lei Chen ◽

...

Keyword(s):

Early Life ◽

Chinese Population ◽

Ascending Aorta ◽

Late Childhood ◽

Cardiac Ultrasound ◽

Multivariate Logistic Regression ◽

Fetal Period ◽

Famine Exposure ◽

Aorta Dilatation ◽

The Relationship

Abstract Background and aims: The relationship between exposure to famine in early life and the risk of ascending aorta dilatation (AAD) in adulthood is still unclear, therefore we aimed to examine the association in a Chinese population. Methods and results: We investigated the data of 2,598 adults that were born between 1,952 and 1,964 in Guangdong, China. All enrolled subjects were categorized into five groups: not exposed to famine, exposed during fetal period, and exposed during early, mid or late childhood. AAD was assessed by cardiac ultrasound. Multivariate logistic regression and interaction tests were performed to estimate the odds ratio (OR) and confidence interval (CI) on the association between famine exposure and AAD. There were 2,598 (943 male, mean age 58.3 ± 3.68 years) participants were enrolled, and 270 (10.4%) subjects with AAD. We found that famine exposure (OR=2.266, 95% CI: 1.477, 3.477, P=0.013) associated with elevated AAD after adjusting for multiple confounders. In addition, compared with the non-exposure group, the adjusted ORs for famine exposure during fetal period, early, mid or late childhood were 1.374 (95% CI: 0.794, 2.364, P=0.251), 1.976 (95% CI: 1.243, 3.181, P=0.004), 1.929 (95% CI: 1.237, 3.058, P=0.004) and 2.227 (95% CI: 1.433, 3.524, P<0.001), respectively. Subgroup analysis showed that the effect of famine exposure on the association with AAD was more pronounced in female, current smokers, people with BMI ≥24 kg/m2 and hypertensive patients. Conclusion: We observed that exposure to famine during early life was linked to AAD in adulthood.

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