Effect of platelet-rich plasma on the degenerative rotator cuff tendinopathy according to the compositions

Abstract Background There are controversies about platelet-rich plasma (PRP) as an established treatment option for rotator cuff (RC) tendinopathy. The purpose of the study was to find the relation of cellular component with clinical efficacy in RC tendinopathy and to find the composition of PRP in treating RC tendinopathy. Methods A total 30 patients were recruited and divided into PRP and control groups. In the PRP group, 2 ml of PRP solution was injected to the hypoechoic lesion of degenerative supraspinatus via 22-gauge syringe with peppering technique. Patients in the control group were taught rotator cuff strengthening exercises. American Shoulder and Elbow Surgeons (ASES), Constant-Murley score, and numeric rating scale (NRS) were measured before, 6 weeks after, 12 weeks after, and 24 weeks after the procedure. PRP compositions were analyzed using the 1 ml of PRP solution. Results Linear regression analysis showed no significant difference of ASES and Constant-Murley scores between the groups at 6 weeks (P = 0.582 and 0.258) and at 12 weeks (P = 0.969 and 0.795) but showed a significant difference at 24 weeks (P = 0.050 and 0.048). Independent t test showed significant group difference of NRS at 6 weeks (P = 0.031) but not at 12 and 24 weeks (P = 0.147 and 0.935). 5.19 pg/ml in IL-1β and 61.79 μg/ml in TGF-β1 were acquired as cutoff values to predict meaningful improvement. The PRP subgroup above IL-1β or TGF-β1 cutoff value showed significant differences in all clinical outcomes compared with the exercise group while the PRP subgroup below the cutoff value showed no significant differences in linear regression analysis. Conclusions Our study can help to find the optimal PRP condition and to enhance the effect of PRP on RC tendinopathy. Trial registration All the patients were registered in our Institutional Ethics Committee (approval number 2014-05-009).

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Comparison of [18F] NaF PET/CT Analysis Methods and Derivation of a Semi-population Input Function for Site Specific Measurements of Bone Formation in a Population With Chronic Kidney Disease Mineral and Bone Disorder

10.21203/rs.3.rs-641228/v1 ◽

2021 ◽

Author(s):

Marie Houmaa Vrist ◽

Jesper Nørgaard Bech ◽

Thomas Guldager Lauridsen ◽

Claire Anne Fynbo ◽

Jørn Theil

Keyword(s):

Regression Analysis ◽

Linear Regression ◽

Linear Regression Analysis ◽

Input Function ◽

Mineral And Bone Disorder ◽

Pet Ct ◽

Significant Difference ◽

Bone Disorder ◽

Non Linear ◽

Patlak Analysis

Abstract PurposeImplementation and comparison of non-invasive dynamic and static whole-body (WB) [18F]NaF PET/CT scan methods to replace invasive bone biopsy, used for quantitative analysis of bone clearance in patients with chronic kidney disease - mineral and bone disorder (CKD-MBD).MethodsSeventeen patients with CKD-MBD underwent a 60-minute dynamic scan followed by a 30-minute static WB scan. Tracer kinetics in four thoracic vertebrae were analyzed using non-linear regression and Patlak analysis using image-derived arterial input functions. We validated the use of a semi-population input function in this population.ResultsSkeletal plasma clearance (Ki) from Patlak analyses correlated well with non-linear regression analysis, but Ki-results using Patlak analysis were lower compared to Ki-results using non-linear regression analysis. However, no significant difference was found between Ki obtained by static WB scans and Ki obtained by dynamic scans using non-linear regression analysis (p=0.29). ConclusionOur results show good correlation between dynamic and static analysis of skeletal plasma clearance with no significant difference between the Ki-results obtained by non-linear regression analysis and the more clinically suitable static scan analysis method. We found lower Ki-results when Patlak analysis was applied. Thus, WB [18F]NaF PET/CT scans can be applied in future studies to measure Ki in CKD-BMD patients, but the results should not be compared uncritically with results obtained by dynamic scans analysis.

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Correlation of CA-125 with different stages of endometriosis

Bangabandhu Sheikh Mujib Medical University Journal ◽

10.3329/bsmmuj.v11i1.35807 ◽

2018 ◽

Vol 11 (1) ◽

pp. 41

Author(s):

Runa Laila ◽

Begum Nasrin ◽

Shayela Shamim ◽

Md. Mozammel Hoque

Keyword(s):

Regression Analysis ◽

Linear Regression ◽

Significant Positive Correlation ◽

Linear Regression Analysis ◽

Stage Iv ◽

Ca 125 ◽

Pelvic Endometriosis ◽

Cancer Antigen ◽

Cutoff Value ◽

The Mean

<p class="Abstract">This study was conducted to evaluate the association of serum cancer antigen (CA-125) level with the severity of pelvic endometriosis. Seventy diagnosed cases of pelvic endometriosis were included in this study. The CA-125 level was estimated in all these patients, cutoff value of the serum CA-125 level was considered 35.0 U/mL. The correlations between serum CA-125 and different stages of endometriosis were evaluated by linear regression analysis. In Stage I of endometriosis, the mean serum CA-125 level was 21.8 ± 15.1 U/mL, in Stage II 26.0 ± 17.3 U/mL, in Stage III 83.2 ± 48.9 U/mL and in Stage IV 117.0 ± 41.6 U/mL. A significant positive correlation (r=0.729; p=0.001) was found between the serum CA-125 and different stages of endometriosis.</p>

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Risk factors for development of obesity in an ethnically diverse CHD population

Cardiology in the Young ◽

10.1017/s1047951118001889 ◽

2019 ◽

Vol 29 (2) ◽

pp. 123-127

Author(s):

Scott J. Weinreb ◽

Abigail J. Pianelli ◽

Sreyans R. Tanga ◽

Ira A. Parness ◽

Rajesh U. Shenoy

Keyword(s):

Body Mass Index ◽

Regression Analysis ◽

Linear Regression ◽

Longitudinal Data ◽

Body Mass ◽

Linear Regression Analysis ◽

Paediatric Population ◽

Post Surgery ◽

Significant Difference ◽

Age Cohort

AbstractObjectivesPrevious cross-sectional studies have demonstrated obesity rates in children with CHD and the general paediatric population. We reviewed longitudinal data to identify factors predisposing to the development of obesity in children, hypothesising that age may be an important risk factor for body mass index growth.Study designRetrospective electronic health records were reviewed in all 5–20-year-old CHD patients seen between 2011 and 2015, and in age-, sex-, and race/ethnicity-matched controls. Subjects were stratified into aged cohorts of 5–10, 11–15, and 15–20. Annualised change in body mass index percentile (BMI%) over this period was compared using paired Student’s t-test. Linear regression analysis was performed with the CHD population.ResultsA total of 223 CHD and 223 matched controls met the inclusion criteria for analysis. Prevalence of combined overweight/obesity did not differ significantly between the CHD cohort (24.6–25.8%) and matched controls (23.3–29.1%). Univariate analysis demonstrated a significant difference of BMI% change in the age cohort of 5–10 (CHD +4.1%/year, control +1.7%/year, p=0.04), in male sex (CHD +1.8%/year, control −0.3%/year, p=0.01), and status-post surgery (CHD 2.03%/year versus control 0.37%, p=0.02). Linear regression analysis within the CHD subgroup demonstrated that age 5–10 years (+4.80%/year, p<0.001) and status-post surgery (+3.11%/year, p=0.013) were associated with increased BMI% growth.ConclusionsPrevalence rates of overweight/obesity did not differ between children with CHD and general paediatric population over a 5-year period. Longitudinal data suggest that CHD patients in the age cohort 5–10 and status-post surgery may be at increased risk of BMI% growth relative to peers with structurally normal hearts.

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Which Hard and Soft Tissue Factors Relate with the Amount of Buccal Corridor Space during Smiling?

The Angle Orthodontist ◽

10.2319/120906-502.1 ◽

2008 ◽

Vol 78 (1) ◽

pp. 5-11 ◽

Cited By ~ 24

Author(s):

Il-Hyung Yang ◽

Dong-Seok Nahm ◽

Seung-Hak Baek

Keyword(s):

Regression Analysis ◽

Soft Tissue ◽

Linear Regression ◽

Multiple Linear Regression ◽

Linear Regression Analysis ◽

Multiple Linear Regression Analysis ◽

Lateral Cephalograms ◽

Significant Difference ◽

Tissue Factors ◽

Buccal Corridor

Abstract Objective: To investigate which hard and soft tissue factors relate with the amount of buccal corridor area (BCA) during posed smiling. Materials and Methods: The samples consisted of 92 adult patients (19 men and 73 women; 56 four first bicuspids extraction and 36 nonextraction treatment cases; mean age = 23.5 years), who were treated only with a fixed appliance and finished with Angle Class I canine and molar relationships. To eliminate the crowding effect on the buccal corridor area, lateral cephalograms, dental casts, and standardized frontal posed smile photographs were obtained at debonding stage and 28 variables were measured. Pearson correlation analysis, multiple linear regression analysis, and independent t-test were used to find variables that were related with buccal corridor area ratio (BCAR). Results: Among the lateral cephalometric and dental cast variables, FMA, lower anterior facial height, upper incisor (U1) exposure, U1 to facial plane, lower incisor (L1) to mandibular plane, L1 to N-B, Sn (subnasale) to soft tissue menton (Me′), Sn to stomodium superius (stms), stms to Me′, and interpremolar width were significantly negatively correlated with BCAR. Occlusal plane inclination and buccal corridor linear ratio did not show any significant correlation with BCAR. Multiple linear regression analysis generated a three-variable model: Sn to Me′, U1 exposure, and sum of tooth material (STM) (R2 = 0.324). There was no significant difference in BCAR between extraction and nonextraction groups. Conclusions: To control the amount of BCA for achieving a better esthetic smile, it is necessary to observe the vertical pattern of the face, amount of upper incisor exposure, and sum of the tooth material.

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Preoperative Anatomy Parameters in Implantable Collamer Lenses

10.21203/rs.3.rs-968382/v1 ◽

2021 ◽

Author(s):

Yanzhen Xue ◽

Yonghong Guo ◽

Ruibo Zhao

Keyword(s):

Regression Analysis ◽

Linear Regression ◽

Anterior Chamber ◽

Linear Regression Analysis ◽

Corneal Thickness ◽

Intraclass Correlation ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Case Series ◽

Significant Difference

Abstract Purpose: To determine patient preoperative anatomical features and the parameters of implantable collamer lenses (ICLs) relevant in explaining vault variability.Setting: Ophthalmology Xi’an Aier Gucheng Eye hospital , Xi’an China.Design: Retrospective case series.Methods:This study comprised 88 eyes of 45 patients implanted with myopic or toric ICLs between May 2021 and August 2021.Pentacam imaging was used for assessing white-to-white (WTW) diameter, central keratometry, anterior chamber depth(ACD), central corneal thickness and vault. Anterior-segment optical coherence tomography（AS-OCT） was used to measure the horizontal anterior chamber angle distance (ATA). Ultrasound biomicroscopy (UBM) was used to measure horizontal and vertical sulcus to sulcus(vSTS). According to different ACD,we divide ACD into shallow group(2.8 to 3.2 mm),medium group(3.2 to 3.5 mm),and deep group(＞3.5mm).Results: Linear regression analysis found significant correlation between WTW diameters and ATA diameters( y= 0.9605x+0.1491,R² = 0.9148),with a coefficient of determinant of 0.9148 (P＜0.01). Linear regression analysis found significant correlation between hSTS and vSTS（y=0.9855x-0.0178,R²=0.1979）,with a coefficient of determinant of 0.1979 (P＜0.01). WTW diameters showed statistically significant difference in shallow and medium ACD (t=-3.28,P＜0.01 ), significant difference in shallow and deep ACD (t=-4.69,P＜0.01 ),there was no correlation in medium and deep ACD(t=-1.41,P＞0.05 ). There was a statistically significant correlation between WTW diameters and hSTS diameters when the ACD was less than 3.5 mm (t=-0.451, P=0.000) (t=1.406, P=0.026),but weak correlation when the ACD was bigger than 3.5 mm(t=1.594, P=0.051). ATA and WTW with a mean difference close to zero(-0.66 mm). Despite the relatively high correlation (intraclass correlation co-efficient =0.689), the range of agreement is quite broad (1.33 mm).Conclusions:ATA measured with AS-OCT can not be used interchangeably with WTW obtained with Pentacam. WTW diameters and hSTS diameters have a statistically significant correlation when the ACD was less than 3.5 mm. WTW, ATA, hSTS and vSTS all should be considered during design the size of lens and regulating the vault after surgery.

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Can the Point of Deflection from Linearity of Heart Rate Determine Ventilatory Threshold in Children?

Pediatric Exercise Science ◽

10.1123/pes.3.3.256 ◽

1991 ◽

Vol 3 (3) ◽

pp. 256-262 ◽

Cited By ~ 6

Author(s):

Anthony D. Mahon ◽

Paul Vaccaro

Keyword(s):

Heart Rate ◽

Regression Analysis ◽

Linear Regression ◽

Ventilatory Threshold ◽

Linear Regression Analysis ◽

Accurate Predictor ◽

Graded Exercise Test ◽

Significant Difference ◽

Graded Exercise ◽

The Relationship

Whether the point of deflection from linearity of heart rate (HRD) coincides with ventilatory threshold (VT) has not been extensively examined in children. The purpose of this study was to assess the relationship between the VO2 measured at VT and the VO2 measured at HRD. Twenty-two boys with a mean age of 10.7 years (±1.0) performed a graded exercise test to determine VT, HRD, and VO2max. There was no significant difference between mean VO2 (ml/kg/min) at VT and at HRD (33.5±3.5 vs. 34.1±4.4; p>0.05). Linear regression analysis revealed a correlation of r = 0.76 (p<0.01) between the VO2 measured at VT and the VO2 measured at HRD. These results indicate that HRD may be an accurate predictor of VT in most but not all children, and caution should be used when interpreting the significance of HRD.

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The Effect OF FDR, NPF, OEOI, and Size Toward ROA (Comparative Study on Indonesian Islamic Bank and Malaysian Islamic Bank Periode 2010-2015)

International Journal of Islamic Business and Economics (IJIBEC) ◽

10.28918/ijibec.v3i1.1426 ◽

2019 ◽

Vol 3 (1) ◽

pp. 12

Author(s):

Anafil Windriya

Keyword(s):

Regression Analysis ◽

Linear Regression ◽

Linear Regression Analysis ◽

Multiple Linear Regression Analysis ◽

Islamic Banks ◽

Operating Income ◽

Independent Variables ◽

Islamic Bank ◽

Chow Test ◽

Significant Difference

This research aims to analyze the influence of Financing to Deposit Ratio (FDR), Non Performing Financing (NPF), Operating Expenses to Operating Income (OEOI), Firm Size toward Return On Asset (ROA). The object of this research are Islamic Bank in Indonesia and Islamic Bank in Malaysia in 2010-2015. Another aim is to determine whether there are differences in effects of FDR, NPF, OEOI and size toward ROA between Islamic Bank in Indonesia and Islamic Bank in Malaysia. Multiple linear regression analysis was used to test the hypothesis in this study. Chow test is used to determine the differences in the effect. The results of this study concluded that FDR, NPF, OEOI and Size effect on ROA simultaneously, both at Indonesian Islamic Bank and Malaysian Islamic Bank. In Indonesian Islamic Bank, independent variables that influence toward ROA are FDR, OEOI and Size. In Malaysia Islamic Bank, only OEOA wich affecting toward ROA. Based on the chow test, can be concluded that there is a significant difference between the Indonesian Islamic Bank and Malaysian Islamic Bank. Results of independent t test showed that the average variable that has a different effect between Indonesia Islamic Banks and Malaysia Islamic Banks is Size.

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Spino cranial angle as a predictor of loss of cervical lordosis after laminoplasty in patients with cervical myelopathy

BMC Surgery ◽

10.1186/s12893-021-01293-1 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Zheng Wang ◽

Jia-Xin Xu ◽

Zhen Liu ◽

Ruo-Yu Li ◽

Zhi-Wei Wang ◽

...

Keyword(s):

Regression Analysis ◽

Linear Regression ◽

Cervical Myelopathy ◽

Linear Regression Analysis ◽

Multiple Linear Regression Analysis ◽

Cervical Lordosis ◽

Significant Difference ◽

Cervical Sagittal Alignment ◽

Sagittal Parameters

Abstract Background To explore the relationship between spino cranial angle (SCA) and loss of cervical lordosis (LOCL), and to determine whether SCA has the ability to predict LOCL for patients with cervical myelopathy. Methods A total of 68 consecutive patients with cervical myelopathy who received laminoplasty (LAMP) were selected to the current study. C2–C7 lordosis was defined as a representation of the cervical alignment. Alignment change > 0° was considered LOCL. Multiple linear regression analysis was applied to evaluate the association between LOCL and various sagittal parameters at preoperative, such as SCA, CL, T1s and cSVA. Linear regression analysis was applied to evaluate the relationships between LOCL and preoperative SCA in each subgroup. Results Patients were assigned to three groups depending on the quartile of preoperative SCA. The first quarter of patients were defined as the low SCA group, the last quarter were defined as the high SCA group and the middle half were defined as the middle SCA group. There was no statistically significant difference in age, sex and the type of OPLL among the three groups. Patients in the low SCA group showed more cervical lordosis before surgery and more LOCL after LAMP (p < 0.001). After linear regression analysis for SCA and LOCL, preoperative SCA was negatively correlated with LOCL in the low SCA group (r = − 0.857, p < 0.001) and high SCA group (r = − 0.515, p = 0.034). However, there was no significant correlation between preoperative SCA and LOCL in the middle SCA group (r = 0.027, p = 0.881). Conclusions Patients with lower SCA had more lordosis preoperatively and performed more LOCL after LAMP at 2 years of follow-up. Both too high or low preoperative SCA were negatively correlated with the degree of LOCL, while when the SCA fluctuates in a suitable range, it is easier to compensate for the changes of cervical sagittal alignment.

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Pengaruh citra merek, kepercayaan merek, dan kepuasan pelanggan terhadap loyalitas merek sepatu NIKE di Surabaya

Journal of Business and Banking ◽

10.14414/jbb.v9i1.1950 ◽

2019 ◽

Vol 9 (1) ◽

pp. 37

Author(s):

Rollaz Dodo Pamungkas

Keyword(s):

Regression Analysis ◽

Data Analysis ◽

Linear Regression ◽

Customer Satisfaction ◽

Brand Loyalty ◽

Brand Image ◽

Linear Regression Analysis ◽

Multiple Linear Regression Analysis ◽

Brand Trust ◽

Significant Difference

This study aimed to test the effect of the brand image, brand trust, and customer satisfaction on brand loyalty NIKE shoes in Surabaya. This quantitative study used SPSS version 16.00 for the data analysis, with the population of Nike shoes in Surabaya. The data were collected using questionnaires towards 80 respondents. They were selected based on the method of purposive sampling. Multiple linear regression analysis was also for analyzing the data. The results showed that (1) there is a significant difference between the variables of brand image on brand loyalty Nike shoes in Surabaya, (2) there is also a significant difference between the variables of confidence in the brand to brand loyalty Nike shoes in Surabaya (3) a significant difference between the variables customer satisfaction on brand loyalty Nike shoes in Surabaya.

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Fasting blood glucose and newborn birth weight of non- diabetic Sudanese women

F1000Research ◽

10.12688/f1000research.8416.1 ◽

2016 ◽

Vol 5 ◽

pp. 641

Author(s):

Abdelmageed Elmugabil ◽

Duria A. Rayis ◽

Ishag Adam ◽

Mohamed F. Lutfi

Keyword(s):

Regression Analysis ◽

Blood Glucose ◽

Birth Weight ◽

Linear Regression ◽

Linear Regression Analysis ◽

Fasting Blood Glucose ◽

Sociodemographic Characteristics ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Significant Difference

Background Although risk factors for abnormal birth weight has been extensively investigated, whether the physiological range of glucose tolerance affects birth weight in non-diabetic mothers needs to be verified by further research. Objectives To assess the effect of maternal sociodemographic characteristics, obstetric and anthropometric measurements, fasting and 2-hour blood glucose levels on birth weight. Methods One hundred and thirty four women were followed from early pregnancy until delivery at Saad Abualila Hospital, Khartoum, Sudan. Fasting and 2-hour glucose levels following administration of 75 g oral glucose was performed in the third trimester. Association between birth weight and maternal sociodemographic characteristics, obstetric and anthropometric measurements, haemoglobin, fasting and 2-hour blood glucose levels were assessed by linear regression analysis. Results The mean (SD) birth weight was 3127.7 (480.0) g, while the 10th and 90th centile were 2500 and 3800 g, respectively. There was no significant difference in the birth weight between male (n=73) and female (n=61) newborns [3167.8 (545.0) vs 3068.9 (384.0) g, P= 0.196]. Likewise there was no significant difference in the birth weight of newborns born to primipara and multipara mothers [3101.7 (529.0) g vs 3151.4 (432.0) g, P= 0.551]. Linear regression analysis demonstrated significant association between fasting blood glucose and birth weight (20 g, P = 0.028). None of the other maternal/fetal characteristics was associated with birth weight, including maternal age, body mass index, gravidity, weight gain during pregnancy, interpregnancy interval, history of miscarriage, haemoglobin level, blood pressure, fetal gender and gestational age. Conclusion In this study fasting blood glucose was found to be predictor of birth weight among neonates of non-diabetic Sudanese mothers.

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