scholarly journals Retained primary teeth in STAT3 hyper-IgE syndrome: early intervention in childhood is essential

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Iris Meixner ◽  
Beate Hagl ◽  
Carolin I. Kröner ◽  
Benedikt D. Spielberger ◽  
Ekaterini Paschos ◽  
...  
Keyword(s):  
Primary Teeth ◽  
Dental Treatment ◽  
Elevated Serum ◽  
Permanent Tooth ◽  
Tooth Eruption ◽  
Permanent Teeth ◽  
Primary Tooth ◽  
Hyper Ige Syndrome ◽  
Tooth Roots ◽  
Midline Defects

Abstract Background STAT3 hyper-IgE syndrome (STAT3-HIES) is a rare primary immunodeficiency that clinically overlaps with atopic dermatitis. In addition to eczema, elevated serum-IgE, and recurrent infections, STAT3-HIES patients suffer from characteristic facies, midline defects, and retained primary teeth. To optimize dental management we assessed the development of dentition and the long-term outcomes of dental treatment in 13 molecularly defined STAT3-HIES patients using questionnaires, radiographs, and dental investigations. Results Primary tooth eruption was unremarkable in all STAT3-HIES patients evaluated. Primary tooth exfoliation and permanent tooth eruption was delayed in 83% of patients due to unresorbed tooth roots. A complex orthodontic treatment was needed for one patient receiving delayed extraction of primary molars and canines. Permanent teeth erupted spontaneously in all patients receiving primary teeth extraction of retained primary teeth during average physiologic exfoliation time. Conclusions The association of STAT3-HIES with retained primary teeth is important knowledge for dentists and physicians as timely extraction of retained primary teeth prevents dental complications. To enable spontaneous eruption of permanent teeth in children with STAT3-HIES, we recommend extracting retained primary incisors when the patient is not older than 9 years of age and retained primary canines and molars when the patient is not older than 13 years of age, after having confirmed the presence of the permanent successor teeth by radiograph.

scholarly journals Retained primary teeth in STAT3 hyper-IgE syndrome: Early intervention in childhood is essential

2019 ◽  
Author(s):  
Iris Meixner ◽  
Beate Hagl ◽  
Carolin I. Kröner ◽  
Benedikt D Spielberger ◽  
Ekaterini Paschos ◽  
...  
Keyword(s):  
Primary Teeth ◽  
Dental Treatment ◽  
Elevated Serum ◽  
Tooth Eruption ◽  
Permanent Teeth ◽  
Primary Tooth ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Hyper Ige Syndrome ◽  
Midline Defects

Abstract Objectives: To optimize dental management we evaluated development of the dentition and long-term outcome of dental treatment in STAT3 hyper-IgE syndrome (STAT3-HIES), a rare primary immunodeficiency clinically overlapping with atopic dermatitis. Next to eczema, elevated serum-IgE, and recurrent infections, STAT3-HIES patients present with characteristic facies, midline defects, and retained primary teeth. Materials and Methods: We assessed dental histories of 13 molecularly defined STAT3-HIES patients by questionnaires, radiographs, and dental investigations. Results: Primary tooth eruption was unremarkable in all STAT3-HIES patients. Primary tooth exfoliation and permanent tooth eruption was delayed in 83% of patients due to unresorbed tooth roots. Permanent teeth erupted spontaneously in all patients receiving primary teeth extraction of retained primary teeth during average physiologic exfoliation time. A complex orthodontic treatment was needed in one patient receiving delayed extraction of primary molars and canines. Conclusion: To enable spontaneous eruption of permanent teeth in children with STAT3-HIES, we recommend extracting retained primary incisors not later than 9 years of age and retained primary canines and molars not later than 13 years of age after having confirmed the presence of the successor permanent teeth by radiograph. Clinical Relevance: The association of STAT3-HIES with retained primary teeth is important knowledge for dentists in any field as timely extraction of retained primary teeth avoids dental complications.

scholarly journals Avulsion and Replantation in Primary Dentition - A Review

2021 ◽  
Vol 10 (9) ◽  
pp. 619-623
Author(s):  
Viddyasagar Prabhakar Mopagar ◽  
Meghana Vasant Phadnis ◽  
Sourabh Ramesh Joshi ◽  
Vikranth Shetty ◽  
Gowri Swaminatham Pendyala
Keyword(s):  
Primary Teeth ◽  
Root Resorption ◽  
Case Reports ◽  
Traumatic Injury ◽  
Primary Root ◽  
Permanent Tooth ◽  
Permanent Teeth ◽  
Successful Outcome ◽  
Primary Tooth ◽  
Stage Of Development

Avulsion of a primary tooth is a disturbing type of traumatic injury occurring in children. Paediatric dentists are likely to encounter a child with an avulsed primary tooth routinely in their clinical practice. Tooth avulsions are common in permanent teeth. However, avulsions can be seen even in primary teeth. The question of replantation of the avulsed tooth has been a focus of debate and controversy since years. The primary and most important factor in these injuries is to calculate the riskbenefit ratio keeping the underlying permanent tooth in mind. Utmost importance has to be given on the care of development and normal eruptive movements of the succedaneous tooth. This is mandatory if any treatment like replantation is to be done. The amount of primary root resorption, stage of development of the underlying permanent tooth, type of splinting to be done etc. needs a lot of attention. Many authors have given their opinions regarding the replantation of primary teeth based on the type of tooth avulsed. Moreover, the evidence might differ as to whether or not replantation might alter the difficulty levels for the eruption process of succedaneous tooth. There is not much evidence regarding the benefits and risks of replantation post avulsion of primary teeth. However, individual authors have reported a successful outcome in their case reports. This article reports a review on avulsed primary teeth replantation. This would enable the dentists to analyze the risks and benefits associated with replantation, thereby guiding them to arrive at the best clinical decision. KEY WORDS Primary Tooth, Avulsion, Replantation.

Development Dental Defects in Permanent Teeth Resulting From Primary Tooth Trauma. A Systematic Review.

2020 ◽  
Author(s):  
Lucía Caeiro Villasenín ◽  
Clara Serna Muñoz ◽  
Amparo Pérez Silva ◽  
Ascensión Vicente ◽  
Andrea Poza Pascual ◽  
...  
Keyword(s):  
Systematic Review ◽  
Primary Teeth ◽  
Tooth Enamel ◽  
Dental Trauma ◽  
Permanent Tooth ◽  
Permanent Teeth ◽  
Primary Tooth ◽  
Development Phase ◽  
Made In

Abstract Children are vulnerable to dental trauma, especially in the first two year of life.The objective was to determine whether trauma in temporary teething causes alterations in the development of permanent teething. Searches were made in May 2020 using PubMed, MEDLINE, MEDES, Scopus, Lilacs, and Embase. Papers in English, German, and Spanish, without restrictions in the year of publication, were included. The quality of the studies was analyzed using the NOS Scale.The search retrieved 537 references, and 7 studies were included for a qualitative analysis. The results showed that trauma to a deciduous tooth can damage the bud of the permanent tooth. Enamel discoloration and/or hypoplasia were the most common sequelae in the permanent teeth after trauma to the primary predecessor. The type and severity of sequelae in the permanent tooth are associated with the development phase of the bud. Children with trauma of their primary teeth should receive check-ups until the eruption of the permanent teeth for the early diagnosis and treatment of possible sequelae. Intrusion of the primary tooth was the trauma that caused the most damage and enamel alterations the most frequent sequelae.

scholarly journals Developmental Dental Defects in Permanent Teeth Resulting from Trauma in Primary Dentition. A Systematic Review

2022 ◽  
Vol 19 (2) ◽  
pp. 754
Author(s):  
Lucía Caeiro-Villasenín ◽  
Clara Serna-Muñoz ◽  
Amparo Pérez-Silva ◽  
Ascensión Vicente-Hernández ◽  
Andrea Poza-Pascual ◽  
...  
Keyword(s):  
Systematic Review ◽  
Primary Teeth ◽  
Tooth Enamel ◽  
Permanent Tooth ◽  
Primary Dentition ◽  
Permanent Teeth ◽  
Primary Tooth ◽  
Development Phase ◽  
Made In

The objective was to determine whether trauma in primary dentition causes alterations in the development of permanent dentition. Searches were made in May 2020 using PubMed, MEDLINE, MEDES, Scopus, Lilacs, and Embase. Papers in English, German, and Spanish, without restrictions in the year of publication, were included. The quality of the studies was analyzed using the NOS Scale. The search retrieved 537 references, and seven studies were included for a qualitative analysis. The results showed that trauma to a deciduous tooth can damage the bud of the permanent tooth. Enamel discoloration and/or hypoplasia were the most common sequelae in the permanent teeth after trauma to the primary predecessor. The type and severity of sequelae in the permanent tooth are associated with the development phase of the bud. Children with trauma of their primary teeth should receive checkups until the eruption of the permanent teeth for the early diagnosis and treatment of possible sequelae. Intrusion of the primary tooth was the trauma that caused the most damage and enamel alterations the most frequent sequelae.

scholarly journals Treatment of a Patient with Multiple Impacted Teeth

2007 ◽  
Vol 77 (4) ◽  
pp. 735-741 ◽  
Author(s):  
Richard Scott Conley ◽  
Scott B. Boyd ◽  
Harry L. Legan ◽  
Christopher C. Jernigan ◽  
Craig Starling ◽  
...  
Keyword(s):  
Case Report ◽  
Treatment Planning ◽  
Orthodontic Treatment ◽  
Primary Teeth ◽  
Permanent Tooth ◽  
Permanent Teeth ◽  
Treatment Sequence ◽  
Impacted Teeth ◽  
Case Complexity ◽  
Multiple Primary

Abstract An impacted or missing permanent tooth can add significant complications to an otherwise straightforward case. When multiple impacted teeth are present, the case complexity increases further. Developing a treatment sequence, determining appropriate anchorage, and planning and executing sound biomechanics can be a challenge. The following case report illustrates a patient reportedly diagnosed with mild scleroderma as an adolescent. He presented for orthodontic treatment as an adult with multiple retained primary teeth and multiple impacted teeth. Diagnosis, treatment planning, and various methods of managing guided eruption of impacted teeth will be discussed. Following orthodontic treatment that required extraction of multiple primary and permanent teeth as well as exposure and ligation of multiple permanent teeth by an oral surgeon, the patient finished with a significantly improved functional and esthetic result.

Management of trauma to the anterior segment of the maxilla: alveolar fracture and primary incisors crown and root fracture

2021 ◽  
Vol 33 (2) ◽  
pp. 16-20
Author(s):  
Muna S Khalaf ◽  
Bayan S Khalaf ◽  
Shorouq M Abass
Keyword(s):  
Soft Tissue ◽  
Primary Teeth ◽  
Alveolar Bone ◽  
Anterior Segment ◽  
Dental Trauma ◽  
Permanent Tooth ◽  
Permanent Teeth ◽  
Normal Position ◽  
Anterior Teeth ◽  
The Impact

Background: An injury to both the primary and permanent teeth and the supporting structures is one of the most common dental problems seen in children. Splinting is usually difficult or impossible to perform in the primary dentition (due to diminutive room size and lack of patient cooperation). Healing must, therefore, occur despite mobility at the fracture line, usually resulting in interposition of connective tissue. In some instances, infection will occur in the coronal pulp. The present study reported a case of trauma to the anterior primary teeth and alveolar bone in a four year old child. The trauma has caused fracture to the crowns and roots of the primary anterior teeth. The following case was managed in a procedure that may provide primary teeth subjected to trauma a better chance than extraction with a better prognosis. Case presentation: a 4 and a half year old child was subjected to trauma in anterior segment of maxilla. Suturing of the torn soft tissue was the first step followed by pulpotomy for the left primary lateral incisor. Fixation of the right primary central and lateral incisors was done by acid etch wire fixation. Both clinical and radiographic follow up was carried out for 6.4 years. Results: healing of the soft tissue was observed after one week and completed after two months. Fixation of the teeth continued for ten months. The fracture lines in the roots remained in position. Clinically there was no sign of any pulpal inflammation or necrosis. Radiographically, no signs of infection to the surrounding tissues could be seen, no resorption in the alveolar bone, external or internal resorption of the root did not happen also. After ten months fixation ended and the wire was removed. At that time there was normal resorption of the roots of the primary incisors in relation with the normal development of the permanent incisors. After 3 years both permanent central incisors erupted in their normal position. After 6.4 years all four permanent incisors erupted into occlusion in their normal position. Conclusion: primary teeth with root fractures and severely mobile coronal fragments can be treated by a conservative approach. The severity of the sequels is directly related to the degree of permanent tooth formation (child’s age), type of dental trauma and extent of the impact. Key words: trauma, primary incisors, fractured crown and root

scholarly journals Evaluation and Comparison of Formocresol and Sodium Hypochlorite as Pulpotomy Medicaments in Treatment of Mandibular Primary Molars - A Randomized Controlled Study

2021 ◽  
Vol 6 (4) ◽  
pp. 105-110
Author(s):  
Nadia Irshad Wani ◽  
Navneet Kour ◽  
Manju Verma
Keyword(s):  
Sodium Hypochlorite ◽  
Primary Teeth ◽  
Main Idea ◽  
Permanent Teeth ◽  
Controlled Study ◽  
Primary Tooth ◽  
Second Molar ◽  
Randomized Controlled ◽  
Group I ◽  
Group Ii

Background: the main idea behind the pulpotomy of a primary tooth is to remove the infected or inflamed coronal pulp tissues and cover the pulp with a suitable medicament or dressing which promotes healing and preserve the vitality of the teeth especially in young permanent teeth. A medicament should be biologically compatible, have healing capabilities, should be non cytotoxic, or mutagenic and with no carcinogenic potential. Aim: the main aim of the study was to compare and evaluate the efficacy of commonly used two medicaments i.e. formocresol and sodium hypochlorite in pulpotomy of mandibular primary teeth. Material and methodology: a randomized controlled single blinded clinical trial was done on 50 subjects of age ranging from 3 to 6 years with bilateral mandibular first or second molar requiring pulpotomy. The subjects were randomly divided into two groups with 25 subjects in each. Group I, consisted of subjects on which formocresol medicament was used after extirpation of coronal pulp while in Group II, 3% sodium hypochlorite was used. Clinical along with the radiographic signs and symptoms were blindly recorded at an interval of 1, 3, 6 and 12 months respectively. Results: Statistically significant results were obtained in group II, when patients treated with 3% sodium hypochlorite. There was no major difference between the two medicaments used, but to the various adverse effects of formocresol, its usage has been limited. Conclusion: within the limitation of the study, it was concluded that sodium hypochlorite medicament proved to have better prognosis and can be suggested as a pulpotomy agent for primary teeth. Although formocresol was found to have similar significant results can also be used as a medicament. Keywords: Formocresol, Pulpotomy, Primary Teeth, Sodium Hypochlorite

Association Between Genetic Polymorphisms in Metaloproteinases of the Matrix and Delayed Tooth Emergence: A Cross-sectional Study

2019 ◽  
Vol 10 (2) ◽  
pp. 91-96
Author(s):  
Silvane Silva Evangelista ◽  
Juliana Arid ◽  
Katia Regina Felizardo Vasconcelos ◽  
Giuseppe Valduga Cruz ◽  
André Luiz Tannus Dutra ◽  
...  
Keyword(s):  
Genetic Polymorphisms ◽  
Cross Sectional Study ◽  
Permanent Tooth ◽  
Tooth Eruption ◽  
Permanent Teeth ◽  
Fisher Exact Test ◽  
Genotype Distribution ◽  
Sectional Study ◽  
Cross Sectional ◽  
Allele Distribution

Background and Aims: Animal models have been demonstrating that MMPs have an important function in the tooth eruption process. The aim of this study was to evaluate the association between genetic polymorphisms in MMP8 and MMP13 and delayed tooth eruption of permanent teeth. Materials and Methods: This cross-sectional study selected 216 children, 9- to 12-year-old, from public schools at Manaus, Amazonas, Brazil. During oral clinical examination, each permanent tooth emerged in the oral cavity was evaluated. Children were considered with delayed tooth eruption when at least one permanent tooth was delayed and were classified in 2 groups: children “with delayed tooth emergency” and “without delayed tooth emergency.” Saliva samples were collected from DNA extraction. The genetic polymorphisms rs17099443 and rs3765620 in MMP8, and rs478927 and rs2252070 in MMP13 were genotyped. Statistical Analysis: PLINK V1.07 ( http://pngu.mgh.harvard.edu/purcell/plink/ ) and GraphPad Prism 5.0 (San Diego, CA, USA) were used. The c2 or Fisher exact test was used to calculate genotypes and alleles distributions. To compare the mean number of delayed teeth according to genotypes, the Kruskal-Wallis test with multiple comparison Dunn test was used. The established alpha for all comparisons was .05. Results: The polymorphism rs17099443 in MMP8 was associated with delayed tooth eruption in the genotype distribution ( P = .05). In the allele distribution, the C allele was underrepresented in children with delayed tooth eruption ( P = .01; OR = 0.61, 95% confidence interval, 0.41–0.9). Conclusion: The genetic polymorphism rs17099443 in MMP8 is associated with delayed tooth eruption.

Hyper-IgE syndrome: a case report

2001 ◽  
Vol 25 (4) ◽  
pp. 333-336 ◽  
Author(s):  
E. Sepet ◽  
D. Özdemir ◽  
N. Aksakalli ◽  
G. Külekçig
Keyword(s):  
Primary Teeth ◽  
Pulmonary Infection ◽  
Elevated Serum ◽  
Hyper Ige Syndrome ◽  
Transmission Electron ◽  
Deciduous Molar ◽  
Reduced Rate ◽  
Therapeutic Doses ◽  
Anti Fungal ◽  
And Staphylococcus Aureus

The hyper-IgE syndrome (HIES) is a rare disorder characterized by pruritic dermatitis, recurrent Staphylococcus skin abscesses and extremely elevated levels of IgE in serum. In this report, an elevenyear-old-boy with hyper-IgE syndrome is presented. He had a coarse facial appearance, pruritic dermatitis, recurrent skin abscesses, pulmonary infection, a reduced rate of resorption of the roots of primary teeth and an elevated serum IgE concentration. The colonization of Candida albicans, Kiebsiella pneumoniae, Escherichia coli and Staphylococcus aureus were found as; (1x102 CFU), (2.2x104 CFU), (2.2x104 CFU) and (2.6x103 CFU) per ml saliva, respectively. Also the pulp of a deciduous molar was investigated with light and transmission electron microscope (TEM). As conclusion, treatment for this condition is lifelong administration of therapeutic doses of a penicillinase-resistant penicillin, with the addition of other antibiotics or anti-fungal agents as required for specific infections.

Root Lengths in 47,XYY Males’ Permanent Teeth

2004 ◽  
Vol 83 (10) ◽  
pp. 771-775 ◽  
Author(s):  
R. Lähdesmäki ◽  
L. Alvesalo
Keyword(s):  
Y Chromosome ◽  
Sex Chromosome ◽  
Permanent Tooth ◽  
Permanent Teeth ◽  
Tooth Crown ◽  
Promoting Effect ◽  
Panoramic Radiographs ◽  
Tooth Roots ◽  
Root Dentin ◽  
Males And Females

Studies on individuals with sex chromosome anomalies have demonstrated the promoting effect of the Y chromosome on tooth crown enamel and dentin growth. The present research investigated permanent tooth root lengths in 47,XYY males. The measurements were made from panoramic radiographs. The results indicate longer tooth roots in 47,XYY males compared with those in control males and females. The promoting effect of the Y chromosome on dental growth thus continues in the form of root dentin after the completion of crown growth. The results, together with those on tooth crown sizes in 47,XYY males, suggest that growth excesses are evident and final, beginning a few months after birth and continuing up to the age of 14 years, at least. The excess root dentin growth in 47,XYY males, as well as sexual dimorphism in the growth of crown and root dentin, might be caused by the same factor on the Y chromosome.

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