scholarly journals Complementary feeding methods in the first year of life: a study protocol for a randomized clinical trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Leandro Meirelles Nunes ◽  
Jordana Führ ◽  
Christy Hannah Sanini Belin ◽  
Paula Ruffoni Moreira ◽  
Renata Oliveira Neves ◽  
...  

Abstract Background The traditional spoon-feeding approach to introduction of solid foods during the complementary feeding period is supported by consensus in the scientific literature. However, a method called Baby-Led Introduction to SolidS (BLISS) has been proposed as an alternative, allowing infants to self-feed with no adult interference. To date, there have been no trials in the Brazilian population to evaluate the effectiveness of BLISS in comparison to the traditional approach. Methods/design To evaluate and compare three different complementary feeding methods. Data on 144 mother-child pairs will be randomized into intervention groups by methods: (A) strict Parent-Led Weaning; (B) strict Baby-Led Introduction to SolidS; and (C) a mixed method. Prospective participants from Porto Alegre, Brazil, and nearby cities will be recruited through the Internet. The interventions will be performed by nutritionists and speech therapists, at 5.5 months of age of the child, at a private nutrition office equipped with a test kitchen where meals will be prepared according to the randomized method. The pairs will be followed up at 7, 9, and 12 months of age. Data will be collected through questionnaires designed especially for this study, which will include a 24h child food recall, questionnaires on the child’s and parents’ eating behavior, oral habits, eating difficulties, and choking prevalence. At 12 months of age, children will undergo blood collection to measure hemoglobin, ferritin, and C-reactive protein, saliva collection for analysis of genetic polymorphisms, and oral examination. Anthropometric parameters (child and maternal) will be measured at the baseline intervention, at a 9 month home visit, and at the end-of-study visit at the hospital. The primary outcome will be child growth and nutritional status z-scores at 12 months; secondary outcomes will include iron status, feeding behavior, acceptability of the methods, dietary variety, choking, eating behaviors, food preferences, acceptance of bitter and sweet flavors, suction, oral habits, oral hygiene behavior, dental caries, gingival health status, and functional constipation. Discussion The trial intends to ascertain whether there are potential advantages to the BLISS complementary feeding method in this specific population, generating data to support families and healthcare providers. Trial registration Brazilian Clinical Trials Registry (ReBEC): RBR- 229scm number U1111-1226-9516. Registered on September 24, 2019.

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Sabina Bacchus ◽  
Rachael Taylor ◽  
Elizabeth Fleming ◽  
Sheila Williams ◽  
Benjamin Wheeler ◽  
...  

AbstractIn Baby-Led Weaning (BLW), infants are offered foods they can pick up and feed themselves from the start of complementary feeding. Infants who are fully BLW are not spoonfed at all by their parents, feeding themselves all their foods instead. The Baby-Led Introduction to SolidS (BLISS) study was a randomised controlled trial of the effect of a modified version of BLW5 on infant growth, iron status, and risk of choking, and provides an opportunity to investigate parents’ experiences of using a baby-led approach to infant feeding. Complementary feeding methods are usually chosen by parents, so it is important to ascertain whether parents find a baby-led method of introducing solids acceptable if they are assigned to follow it. This is both to determine whether it would be feasible to randomise them to follow BLW in future randomised controlled trials and because, if beneficial effects of BLW are shown, policy makers need to know whether parents would find it acceptable to follow BLW. The aim of this analysis was to determine the acceptability to parents of a baby-led approach to complementary feeding when their infant was 7 to 12 months of age. In total, 206 participants were randomised to Control (n = 101) or BLISS (n = 105) groups in the third trimester of pregnancy. When the infants were 7, 8, 9, and 12 months of age, questionnaires were administered to determine parents’ happiness and frustration with their feeding method, and attitudes regarding its convenience, mess, and expense. Food cost was estimated using supermarket prices linked to a 3-day weighed diet record collected at 7 months of age. Both groups reported high levels of happiness and convenience, but also reported finding complementary feeding very frustrating. There were two significant differences between the groups – the BLISS group reported less messiness, and were more likely to perceive their method as expensive. The actual food cost per day was not statistically significantly different between the two groups (NZ$1.70 for BLISS, NZ$1.90 for Controls). In conclusion, parents did not find a baby-led approach to introducing solids any less acceptable than control parents found standard infant feeding. It is, therefore, feasible to run studies where parents are randomised to follow a baby-led approach to complementary feeding and, should health advantages to BLW be identified, parents are likely to find BLW acceptable to follow.


2013 ◽  
Vol 18 (1) ◽  
Author(s):  
Elizabeth M. Yako ◽  
Noreen P.B. Nzama

The focus of this study was to explore and describe influences on decision making related to infant feeding methods in the context of HIV and AIDS. Study objectives were: (1) to explore and describe the influences on decision making related to infant feeding methods selected by the mother during the antenatal period and (2) to describe the reasons related to a change in infant feeding method in the postnatal period. This cross-sectional study used the quantitative approach and a descriptive design. A convenience sample of 60 mothers in the prevention of mother-to-child transmission programme participated in this study. Data were collected six weeks post-delivery and analysed using SPSS 17.0 software for Windows. The mean age of the mothers was 26.5 years, range 19 to 41 years (SD 5.3). At six weeks 73% (n = 44) of the mothers maintained the infant feeding method selected antenatally and 27% (n = 16) had changed methods. Using a Chi-square test, the difference between groups was significant (x2 [df 1] = 19, p < 0.000). Every HIV-positive mother (100%, n = 28) continued with the method selected antenatally, compared with 50% (n = 16) of all HIV-negative mothers (n = 32). The reasons for deciding to change methods included going back to school or work; illness of babies; painful breasts; and advice from significant others. Most mothers maintained the feeding methods selected antenatally. HIV-positive mothers were more likely to adhere to the initial decisions made antenatally than HIV-negative mothers.Hierdie studie is gedoen om deeglike navorsing uit te voer en om ‘n beskrywende verslag te kan lewer rakende die invloed van besluitneming met die voedings metodes op babas in die konteks van MIV en VIGS. (1) Deeglike navorsing om beskrywende verslag te kan lewer rakende die besluitnemings met betrekking tot die baba voedings metodes wat deur die moeder geselekteer is gedurende die voorgeboorte periode, en (2) om die redes te beskryf aangaande die verandering in die baba voedings metode nageboortelike periode.Kwantitiewe benadering was gebruik, waartydens 60 moeders deelgeneem het, aan die oordraagbaarheid van moeder na baba. Inligting was ingewin ses weke na geboorte van die baba. Die gemiddelde ouderdom van die moeders was 26.5 jaar, gewissel tussen die ouderdomme van 19 tot 41 jaar (SD 5.3). Op ses weke het 73% (n = 44) van die moeders volgehou met die voedingsmetode wat hulle geselekteer het voorgeboortelik. Sewe-en-twintig (n = 16) het die verkose metodes verander. Die ‘Chi-square’ toets was gebruik, en die verskil tussen die groepe was beduidend (x² [df 1] = 19, p < 0.000). Elke MIV-positiewe moeder (100%, n = 28) het voortgegaan met die metode wat hulle voorgeboortelik verkies het, in vergeleke met 50% van moeders (n = 16) wat MIV negatief was (n = 32). Die redes vir die veranderings, was om teruggekeer na hul werk of skool, borste wat pyn en deur die invloed van ander invloedryke mense. Die meeste moeders het gebly by hul metode wat hulle voorgeboortelik gekies het, spesiaal MIV-positiewe moeders.


2019 ◽  
Vol 15 (4) ◽  
Author(s):  
Justine Briaux ◽  
Sonia Fortin ◽  
Yves Kameli ◽  
Yawavi Agboka ◽  
Magali Romedenne ◽  
...  

2013 ◽  
Vol 11 (4) ◽  
pp. 815-828 ◽  
Author(s):  
Rebecca A. Heidkamp ◽  
Mohamed Ag Ayoya ◽  
Ismael Ngnie Teta ◽  
Rebecca J. Stoltzfus ◽  
Joseline Pierre Marhone

2013 ◽  
Vol 684 ◽  
pp. 303-306
Author(s):  
Eugene Rhee ◽  
Ji Hoon Lee

There are various feeding methods of antenna like as coaxial probe, coupling, parasitic elements, and impedance matching. This paper adopted the microstrip line method as the feeding method of the antenna. The high frequency structure simulator is used to analyze the characteristics of the T-shaped microstrip antenna with various patch dimensions. In comparison with the basic microstrip antenna, this proposed T-shaped microstrip antenna with 40.38 % of patch dimensions has the optimum characteristics of resonant frequency, return loss, and radiation pattern at 2.0 GHz band.


2019 ◽  
Vol 6 ◽  
pp. 2333794X1882194
Author(s):  
Lourdes Huiracocha-Tutiven ◽  
Adriana Orellana-Paucar ◽  
Victoria Abril-Ulloa ◽  
Mirian Huiracocha-Tutiven ◽  
Gicela Palacios-Santana ◽  
...  

We assessed the development, nutritional status, and complementary feeding of 12- to 23-month-old children from Cuenca, Ecuador in 2013. Ecuador, an upper-middle-income country, developed a child policy in accordance with World Health Organization (WHO) guidelines. We collected cross-sectional survey data. Child development was assessed using the Integrated Management of Childhood Illness Guide–2011. The nutritional status was defined with WHO Child Growth Standards−2006. We investigated nutrient density, WHO Infant and Young Child Feeding Indicators, and nutrient supplementation intake of the complementary feeding. In all, 11.7% of children had “possible developmental delay,” stunting was identified in 29.4% of the children, and 25.3% faced overnutrition (overweight risk/overweight/obesity). The complementary feeding composition can be summarized as having adequate fat, high energy (MJ/day) and protein, and low iron and zinc. Children with “possible developmental delay” received less iron ( P < .05) than children with normal development. Overall, 30.4% of children had minimum dietary diversity. A total of 47.7% of children received nutrient supplementation. This epidemiological profile of infants remains a challenge for Ecuador’s health programs.


2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Karolina Woziwodzka ◽  
Jolanta Malyszko ◽  
Małgorzata Banaszkiewicz ◽  
Ewa Koc- Żorawska ◽  
Paulina Dumnicka ◽  
...  

Abstract Background and Aims Zonulin is a haptoglobin 2 precursor, that regulates the intestinal permeability. As a double-chain form it takes part in scavenging haemoglobin. Chronic inflammation is common complication of chronic kidney disease which affects iron metabolism. The most frequent manifestation of multiple myeloma is anaemia in up to 73% of patients. Serum concentrations of zonulin are associated with inflammation process, age, kidney failure and iron status and anaemia. The aim of the study was to analyse zonulin as a marker of anaemia in MM patients and investigate its relationship with acclaimed parameters of renal failure, inflammation, bone metabolism and stages of MM. Method The studied group of seventy-three patients with MM (67 symptomatic, 6 smoldering) included 35 women and 38 man, with mean age 69 ± 10 years. Median (IQR) of time from initial MM diagnosis was 36 (17; 69) months. Forty patients were in ISS stage 1, 15 in stage 2, and 12 in stage 3 at the time of blood collection. Remission of MM was diagnosed in 52 patients and stable or progressive disease in 21. Twenty-six patients had eGFR &lt;60 ml/min/1.73 m2. The examined parameters included creatinine, urea, serum monoclonal protein, albumin, ferritin, blood hemoglobin and NT-proBNP. The association between zonulin, markers of MM stages and renal and bone markers were determined by the Pearson's test and multivariate stepwise regression analysis. The p-value &lt;0.05 was considered statistically significant. Results Median (IQR) serum zonulin in the studied group was 23.9 (19.9; 27.4) ng/ml. There were no differences in zonulin concentrations between patients with smoldering versus symptomatic MM (p=0.4), with ISS 1 to 3 (p=0.7), with remission versus stable or progressive MM (p=0.9), or with eGFR &lt;60 ml/min/1.73 m2 versus those with higher eGFR (p=0.6). Also, zonulin did not differ between subjects with and without anemia (Hb&lt; the lower reference limit) (p=0.4). In whole studied group, significant correlations were observed between zonulin and serum albumin (R=0.30; p=0.009), creatinine (R=-0.28; p=0.018), eGFR (R=0.26; p=0.025), ferritin (R=0.34; p=0.013), NT-proBNP (R=-0.32; p=0.006). Moreover, in patients with symptomatic MM, zonulin correlated with monoclonal protein in serum (R=-0.29; p=0.046), blood hemoglobin (R=0.27; p=0.027), and age (R=-0.24; p=0.044). In multiple regression, serum concentrations of monoclonal protein (beta=-0.48 ± 0.16; p=0.006) and ferritin (beta=0.34 ± 0.14; p=0.023) as well as ISS stage 3 (beta=0.40 ± 0.18; p=0.034) were identified as independent predictors of zonulin concentrations. Conclusion Zonulin as a biomarker may promote diagnosis of etiology and management of MM-associated anaemia, which can contribute to biomarker-targeted therapeutic interventions. Early treatment may result in improved life expectancy in patients with MM and increase their quality of life.


2013 ◽  
Vol 163 (2) ◽  
pp. 416-423.e4 ◽  
Author(s):  
Nancy F. Krebs ◽  
Laurie G. Sherlock ◽  
Jamie Westcott ◽  
Diana Culbertson ◽  
K. Michael Hambidge ◽  
...  

PEDIATRICS ◽  
2017 ◽  
Vol 140 (1) ◽  
pp. e20163459 ◽  
Author(s):  
Lora L. Iannotti ◽  
Chessa K. Lutter ◽  
Christine P. Stewart ◽  
Carlos Andres Gallegos Riofrío ◽  
Carla Malo ◽  
...  

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 162-162
Author(s):  
Gabriela Montenegro-Bethancourt ◽  
Taylor Wallace ◽  
Peter Rohloff ◽  
Elizabeth Yakes Jimenez ◽  
Gabriela Proaño ◽  
...  

Abstract Objectives Studies in Ecuador and Malawi have demonstrated mixed effects of interventions involving daily complementary feeding of eggs on child growth. For example, in Malawi, the egg intervention had no overall effect on child development. There is a need to test the effects of egg interventions on child growth and development in other settings with high prevalence of stunting and in the context of other nutritional interventions. The Saqmolo’ (i.e.,“egg” in the Mayan language, Kaqchiquel) study aims to evaluate the impact of adding 1 egg per day to local standard nutrition care (LSNC) on child development, in rural Maya infants from Guatemala. Methods In a community-based, individually randomized, controlled comparative effectiveness trial among rural indigenous Maya children (n = 1200), starting at 6–9 months at baseline, we will compare the impact of adding one egg per day to LSNC with LSNC alone. LSNC includes: growth monitoring, medical care, deworming medication, multiple micronutrient powders for point of use food fortification, and individualized complementary and responsive feeding education for caregivers. Intervention and control groups will be visited once per month during 6-months and adherence will be monitored during the visits and through phone calls for the first 2 months in both groups at the same frequency. The primary outcome is differences in child global development (measured by Caregiver Reported Child Development Instruments –CREDI-and the Guide for Monitoring Child Development GMCD); secondary outcomes include: growth (z-scores for weight for age, length for age, weight for length, and head circumference for age), and diet quality (using the World Health Organization's infant and young child feeding indicators). Results N/A (submitting study protocol abstract). Conclusions This study will provide new evidence on the potential effect of increased egg accessibility in high prevalence stunting areas along with integrated nutrition care on child development. The results may help to inform public health decision-making regarding resource allocation for effective nutrition interventions during the complementary feeding period in Guatemala. Funding Sources This work was supported by the Academy of Nutrition and Dietetics Foundation via an investigator-initiated research grant from the Egg Nutrition Center.


Sign in / Sign up

Export Citation Format

Share Document