Hematological abnormalities in patients with malaria and typhoid in Tamale Metropolis of Ghana

Portal hypertension (PHT) leads to several alterations on hematological indices (HI). The aim of the study is to investigate the differences in HI between cirrhotic subjects and subjects who have noncirrhotic PHT (NCPHT). This retrospective study included 328 patients with PHT (239 cirrhosis and 89 NCPHT). Demographic and clinical features, endoscopic and radiological findings, and HI including neutrophil to lymphocyte ratio (NLR) at the time of PHT diagnosis were recorded. Severity of cirrhosis was assessed according to the Child–Turcotte–Pugh (CTP) classification and Model for End-Stage Liver Disease (MELD) scores. Hematological abnormalities were found in 92.5% of cirrhotic patients and in 55.1% of patients with NCPHT (p < 0.001). While thrombocytopenia was the most common HI in patients with cirrhosis, anemia was the most prevalent HI in NCPHT group. In the cirrhotic group, the NLR was the only parameter to differentiate each CTP group from two others. The NLR value increased with the severity of cirrhosis (2.28 ± 0.14 in CTP-A, 2.85 ± 0.19 in CTP-B and 3.26 ± 0.37 in CTP-C). The AUROC of NLR was 0.692 for differentiating compensated cirrhotic patients from decompensated. Hematological abnormalities are more prevalent and more severe in cirrhotic patients compared to patients with NCPHT. NLR may be used to assess the severity of cirrhosis.

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Detection of Bartonella spp. in neotropical felids and evaluation of risk factors and hematological abnormalities associated with infection

Veterinary Microbiology ◽

10.1016/j.vetmic.2009.10.002 ◽

2010 ◽

Vol 142 (3-4) ◽

pp. 346-351 ◽

Cited By ~ 12

Author(s):

A.M.S. Guimaraes ◽

P.E. Brandão ◽

W. Moraes ◽

S. Kiihl ◽

L.C. Santos ◽

...

Keyword(s):

Risk Factors ◽

Hematological Abnormalities

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Biallelic ZNFX1 variants are associated with a spectrum of immuno‐hematological abnormalities

Clinical Genetics ◽

10.1111/cge.14081 ◽

2021 ◽

Author(s):

Salem Alawbathani ◽

Ana Westenberger ◽

Natalia Ordonez‐Herrera ◽

Mariam Al‐Hilali ◽

Homoud Al Hebby ◽

...

Keyword(s):

Hematological Abnormalities

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Hematological abnormalities in HIV infected individuals in correlation to CD4 counts and ART status

Asian Journal of Medical Sciences ◽

10.3126/ajms.v7i4.14033 ◽

2016 ◽

Vol 7 (4) ◽

pp. 14-18 ◽

Cited By ~ 1

Author(s):

R Raman Thulasi ◽

D Manimaran ◽

G Hemanathan ◽

Tameem Afroz ◽

Radha Sagar

Keyword(s):

Opportunistic Infections ◽

Hematological Parameters ◽

Cd4 Count ◽

Health Concern ◽

Medical Sciences ◽

Cd4 Counts ◽

Medical Centers ◽

Hematological Abnormalities ◽

Set Up ◽

One Year

Background: HIV is pandemic and remains as a public health concern for many decades. This infection though associated with many opportunistic infections and neoplasms, it is further complicated with marked hematological abnormalities. The aim of this study is to determine the magnitude & severity of hematological abnormalities in HIV infected individuals and also to analyze these abnormalities in correlation with the CD4 counts. We also compared these hematological abnormalities in patients on ART and those not on ART.Materials and Methods: The study was conducted for a period of one year, on 120 HIV positive cases including both patients on ART & not on ART. Controls with similar age and sex distribution was set up. The blood samples were collected and processed in an automated cell counter. The parameters were tabulated and analyzed with respect to CD4 count & ART status.Results: Among the total of 120 HIV cases, 77% had anemia, 21% had leucopenia and 5% had thrombocytopenia. The magnitude and severity of anemia, leucopenia, thrombocytopenia and other parameters was found to be more in patients not on ART, when compared to patients on ART. Similarly, the magnitude and severity of most of hematological abnormalities were inversely proportional to the CD4 count in non-ART cases but not with cases on ART.Conclusion: The basic hematological parameters can be used as a prospective screening test to assess the severity and progression of HIV infection when CD4 count is not available. These parameters can also be used to assess the response to anti-retroviral treatment. Therefore, these basic hematological investigations readily available at all medical centers are of great use while treating HIV infected patients.Asian Journal of Medical Sciences Vol.7(4) 2016 14-18

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Assessment of cancer and noncancer health risks from exposure to PAHs in street dust in the Tamale Metropolis, Ghana

Journal of Environmental Science and Health Part A ◽

10.1080/10934529.2013.728914 ◽

2013 ◽

Vol 48 (4) ◽

pp. 408-416 ◽

Cited By ~ 7

Author(s):

Samuel Obiri ◽

Samuel J. Cobbina ◽

Frederick A. Armah ◽

Isaac Luginaah

Keyword(s):

Health Risks ◽

Street Dust ◽

Tamale Metropolis

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Phenol poisoning in three dogs

Journal of the American Animal Hospital Association ◽

10.5326/15473317-36-4-317 ◽

2000 ◽

Vol 36 (4) ◽

pp. 317-321 ◽

Cited By ~ 10

Author(s):

TL Gieger ◽

SS Correa ◽

J Taboada ◽

AM Grooters ◽

AJ Johnson

Keyword(s):

Oral Administration ◽

Supportive Care ◽

Coal Tar ◽

Endoscopic Examination ◽

Gastric Ulceration ◽

The Internet ◽

Muscle Enzymes ◽

Hematological Abnormalities ◽

Mucosal Necrosis

Three adult dogs were evaluated following oral administration of phenol by the owner. All three dogs experienced severe oral and gastric ulceration. Hematological abnormalities included neutropenia with the presence of toxic neutrophils, thrombocytopenia, and increased muscle enzymes. Endoscopic examination was performed, and biopsies yielded a diagnosis of gastric mucosal necrosis in two of the dogs. Following supportive care, the dogs recovered completely. Phenol is a caustic, highly poisonous derivative of coal tar. The dogs of this report were poisoned inadvertently by their owner who received misinformation concerning the use of this chemical via the Internet.

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Effect Of Maternal Growth Monitoring Knowledge On Stunting, Wasting And Underweight Among Children 0-18 Months In Tamale Metropolis Of Ghana

10.21203/rs.2.16457/v2 ◽

2019 ◽

Author(s):

Mohammed Bukari ◽

Muzamil Mohammed Abubakari ◽

Mohammed Majeed ◽

Abdul-Razak Abizari ◽

Anthony Wemakor ◽

...

Keyword(s):

Nutritional Status ◽

Cross Sectional Study ◽

Growth Monitoring ◽

Knowledge Level ◽

Sectional Study ◽

Chi Square ◽

Cross Sectional ◽

Exact Test ◽

Tamale Metropolis ◽

Structured Questionnaire

Abstract This study sought to assess maternal growth monitoring knowledge and its effect on stunting, wasting and underweight among children 0-18 months in the Tamale Metropolis. An analytical cross-sectional study design, involving 340 mother-child pairs randomly selected from 4 health facilities in the Tamale Metropolis, was used. A structured questionnaire was used to collect information on socio-demographic characteristics and maternal growth monitoring knowledge. Weight and length of children were taken to assess nutritional status (stunting, underweight and wasting). Chi-square/Fisher’s exact test was used to determine the association between maternal growth monitoring knowledge level and child nutritional status.This study sought to assess maternal growth monitoring knowledge and its effect on stunting, wasting and underweight among children 0-18 months in the Tamale Metropolis. An analytical cross-sectional study design, involving 340 mother-child pairs randomly selected from 4 health facilities in the Tamale Metropolis, was used. A structured questionnaire was used to collect information on socio-demographic characteristics and maternal growth monitoring knowledge. Weight and length of children were taken to assess nutritional status (stunting, underweight and wasting). Chi-square/Fisher’s exact test was used to determine the association between maternal growth monitoring knowledge level and child nutritional status.

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