scholarly journals Kimura’s disease affecting multiple body parts in a 57-year-old female patient: a case report

2019 ◽  
Vol 15 (1) ◽  
Author(s):  
Bo Yu ◽  
Guoxing Xu ◽  
Xiaofan Liu ◽  
Wen Yin ◽  
Hao Chen ◽  
...  

Abstract Background Kimura’s disease (KD) is a rare chronic inflammatory disease with unknown etiology. It usually manifests as a painless soft tissue mass or subcutaneous nodule on one side of the patient’s head and/or neck and rarely affects multiple parts of the body. The disease is more common among young Asian males. Case presentation A 57-year-old Chinese woman complained of multiple masses on her body surface. Ultrasonography was used to examine the retroperitoneal, bilateral neck, bilateral supraclavicular, bilateral axillary, and bilateral inguinal superficial lymph nodes. Enlargement of multiple lymph nodes was found in all areas. Many solid nodules were also found in the right parotid gland and right posterior neck area, respectively. Numerous solid nodules were seen on the left chest wall. Laboratory tests showed that the percentage of eosinophils in the whole blood was 39.40%, total immunoglobulin E (IgE) level was > 5000 kU/L, and serum special IgE to Phadiatop (inhaled allergens) and fx5 (food allergens) were 1.01 and 1.04 kUA/L, respectively. After a complete examination, the masses located in the right neck, retroauricular and left axillary regions, and left chest wall were resected directly. Postoperative pathological findings revealed KD. Conclusions The case discussed in this study is extremely rare and did not meet the common affected areas and age characteristics of KD. This presentation can be used to improve disease awareness among physicians.

Author(s):  
Anne Phillips

No one wants to be treated like an object, regarded as an item of property, or put up for sale. Yet many people frame personal autonomy in terms of self-ownership, representing themselves as property owners with the right to do as they wish with their bodies. Others do not use the language of property, but are similarly insistent on the rights of free individuals to decide for themselves whether to engage in commercial transactions for sex, reproduction, or organ sales. Drawing on analyses of rape, surrogacy, and markets in human organs, this book challenges notions of freedom based on ownership of our bodies and argues against the normalization of markets in bodily services and parts. The book explores the risks associated with metaphors of property and the reasons why the commodification of the body remains problematic. The book asks what is wrong with thinking of oneself as the owner of one's body? What is wrong with making our bodies available for rent or sale? What, if anything, is the difference between markets in sex, reproduction, or human body parts, and the other markets we commonly applaud? The book contends that body markets occupy the outer edges of a continuum that is, in some way, a feature of all labor markets. But it also emphasizes that we all have bodies, and considers the implications of this otherwise banal fact for equality. Bodies remind us of shared vulnerability, alerting us to the common experience of living as embodied beings in the same world. Examining the complex issue of body exceptionalism, the book demonstrates that treating the body as property makes human equality harder to comprehend.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Kochu Therisa Karingada ◽  
Michael Sony

PurposeThe COVID-19 pandemic lockdown has caught many educational institutions by surprise and warranted an abrupt migration from offline to online learning. This has resulted in an education change, without any time for due consideration, as regards its impact on musculoskeletal disorders (MSD) on students. The purpose of this study is to investigate MSD related to online learning during the COVID-19 pandemic lockdown.Design/methodology/approachA cross-sectional study was conducted on undergraduate students in India. In total, 261 students participated in this online survey.FindingsThe study finds that around 80% of students have reported some symptom in the head, neck and eyes since they started online learning. In total, 58% have reported MSD symptom in the right shoulder and 56% in the right hand fingers. Besides, more than 40 % of students experienced some MSD symptoms, in almost all the body parts studied, due to online learning. Correlation analysis is conducted between time spent on online learning per day and MSD symptoms.Originality/valueThis is the first study conducted on MSD and online learning during COVID-19 pandemic.


Crustaceana ◽  
2014 ◽  
Vol 87 (4) ◽  
pp. 476-488 ◽  
Author(s):  
Michio Imafuku ◽  
Hisakazu Ikeda

The body of a hermit crab shows asymmetrical morphology, which may be related to utilization of the dextral shell. To examine the effect of the shell, we reared Pagurus filholi (De Man, 1887) from the glaucothoe stage to full-sized adults, in a sinistral shell, in a straight tusk shell, without a shell, and in a normal dextral shell as a control. Body parts that show the most conspicuous asymmetry, uropods, pleopods and chelipeds, were checked at the time of the shedding of exuviae during rearing. No inversion of laterality on these characters was observed. However, in crabs subjected to conditions other than a dextral shell, the otherwise rather short right uropod became somewhat extended, and in those reared in sinistral shells, the right major cheliped was more enlarged.


2018 ◽  
Vol 9 (7) ◽  
pp. 207-211 ◽  
Author(s):  
Vivek Kumar ◽  
Navneet Mittal ◽  
Yiwu Huang ◽  
Jasminka Balderracchi ◽  
Huo Xiang Zheng ◽  
...  

Kimura’s disease (KD) is a rare, benign disorder characterized by subcutaneous masses with regional lymph-node enlargement. It is considered to be due to chronic inflammation of unclear etiology. Most cases have been reported in young, 20–30-year-old men of Asian descent. The diagnosis of KD is based on pathological features and elevated immunoglobulin E levels. Characteristic pathological features include intact lymph-node architecture, florid germinal center hyperplasia, extensive eosinophilic infiltrates, and proliferation of postcapillary venules. However, these features can also be seen in Hodgkin’s disease or T-cell lymphoma, therefore, cases presenting as KD pose a diagnostic challenge. We report a case series of two cases with suspected KD at initial presentation, with one patient eventually diagnosed with Hodgkin’s disease after clinical progression. The first case was a 45-year-old Asian man who presented with bilateral thigh masses and significantly enlarged inguinal lymph nodes. The histopathology was characteristic and the patient had stable disease on treatment with cetirizine for 20 months. The second case was a 29-year-old African-American man who had progressive enlargement of the right neck lymph nodes extending into the mediastinum, with the original biopsy suggestive of KD. An initial search for Reed–Sternberg cells using immunohistochemical staining for CD15 and CD30 was negative. However, the patient developed neurological symptoms corresponding to tumor extension to the cervical and thoracic neural foramina. A repeat biopsy showed a lack of nodal structure and atypical large cells that were positive for CD30 staining. The patient was treated with chemotherapy with good response. We emphasize the importance of following the clinical course to render an accurate diagnosis. Both cases showed extensive eosinophilic infiltration and other KD-like pathological features. However, KD is rare; not missing a malignant diagnosis lies in high clinical suspicion and repeated exhaustive work up.


2021 ◽  
Vol 10 (1) ◽  
pp. 85-91
Author(s):  
R. V. Ukrainets ◽  
Yu. S. Korneva

Endometriosis nowadays still a disease with an undisclosed pathogenesis. This article demonstrates and explains the possibility of different variants of dissemination of endometrioid cells in the body with the formation of foci of extragenital endometriosis in organs and tissues remote from the pelvis, complementing and confirming the theory of utero-peritoneal reflux in the development of endometriosis as the most reasonable. Endometrioid heterotopias have a more developed lymphatic network compared to the normal endometrium due to active lymphangiogenesis, and, having a tendency to invasive growth, endometrioid heterotopia is a source of endometrioid cells spreading along the direction of lymph outflow from the most typical locations (pelvic organs) with damage to the inguinal and pelvic lymph nodes. Lymphatic dissemination in adenomyosis is observed in every fourth patient, which requires revision of the surgery protocol with excision of regional lymph nodes to prevent relapses. The presence of cases of pulmonary endometriosis and endometrioid liver cysts makes hematogenic dissemination of endometriosis from the primary source in the pelvic region obvious. The most frequent localizations of endometrioid heterotopias are located near the corresponding venous plexuses of the small pelvis, the outflow from which occurs mainly through the inferior vena cava, without anatomical obstacles for hematogenic dissemination of endometrioid cells with subsequent lung damage. For liver involment, it is likely that endometriosis in the distal parts of the colon is important, the venous outflow from which is directed to the portal vein system. Endometriosis of the diaphragm – is an example transcoelomic spread with predominant location on the right dome of the diaphragm, as the right subphrenic space communicates with the pelvic cavity through the right lateral channel, which justifies the possibility of such involments of the diaphragme in context of the theory of uteroperitoneal reflux.Thus, the theory of menstrual regurgitation and the theory of hemato-lymphatic dissemination are components of a single pathogenetic model of the distribution of endometrioid cells in the body.


Author(s):  
Mohammad Hasil Tamzil ◽  
Budi Indarsih

The study was designed to determine the size of some body parts of the Super Kampong chicken and its relationship with body weight. The study was conducted at the Teaching Farm of Animal Science Faculty, University of Mataram, in Lingsar Village, West Lombok. The study used 60 male and 96 female Super Kampong chickens which were maintained intensively. The variables observed were body weight, head circumference, neck length, wing length, back length, chest circumference, chest width, upper and lower thigh length, metatarsus length, metatarsus circumference, and third finger length. Measurements were made for each individual bird at 13 weeks of age using yarn then measured with a tape measure, while the dimension of chest width was assigned  by measuring the distance between the right and right sides of the chest using calipers. The results found that the body parts that had the biggest contribution to the body weight of the Super Kampong chickens at 13 weeks old were the size of the lower thigh length in the male chicken and the size of the chest circumference in the female chicken.


2000 ◽  
Vol 79 (3) ◽  
pp. 195-199 ◽  
Author(s):  
Sebastian J. Karavattathayyil ◽  
John R. Krause

Kimura's disease is a rare, idiopathic condition that usually affects young men of Asian descent. The disease is characterized by swelling and lesions in the head and neck region, with involvement of the subcutaneous soft tissue, major salivary glands, and lymph nodes. Patients almost always have eosinophilia and elevated serum immunoglobulin E levels. The diagnosis is established by biopsy. Kimura's disease is usually self-limiting. Its etiology is unknown but is thought to be a manifestation of an aberrant allergic response. In this paper, we describe the case of a 30-year-old patient who was diagnosed with Kimura's disease at our institution.


2014 ◽  
Vol 29 (2) ◽  
pp. 86-93 ◽  
Author(s):  
Claudia Spahn ◽  
Céline Wasmer ◽  
Franziska Eickhoff ◽  
Manfred Nusseck

OBJECTIVES: For violinists, it is common practice to play while standing or sitting. When playing in an orchestra, generally two persons share one music stand, with one sitting to the right and the other to the left of the stand. The present study investigated specific movement patterns while playing in these different positions. METHODS: Using a posturographic device and 3D motion capture, the body weight distributions and specific body movements of 19 violinists were analyzed. RESULTS: Results showed unbalanced weight distributions while sitting in front of or oriented to the right of the music stand compared to the almost even distributions while standing or oriented to the left of the stand. Analyses of movement patterns showed significant differences between standing and sitting, mainly in the upper body parts with less movability while sitting. While sitting in front of or oriented to the right of the music stand, the right bowing arm showed more restricted movements compared to other positions. CONCLUSION: The playing positions are discussed with regard to possible physiological stress and health risks. The study emphasizes the importance of different playing positions and offers starting points for discussion of postural influences and sensible handling of the instrument in performance and practice for violinists.


1995 ◽  
Vol 167 (3) ◽  
pp. 350-361 ◽  
Author(s):  
Iain McGilchrist ◽  
John Cutting

BackgroundDelusions relating to the body, a ready source of information about the immediate experiences of psychotic patients, have not been systematically studied. We attempted an account of the phenomena, looking for differences between diagnostic groupings in the type and lateralisation of such phenomena, and for evidence of localisation.MethodSomatic delusions elicited at interview with 550 Research Diagnostic Criteria-diagnosed psychotic patients were categorised according to content, and the results were compared across diagnostic groupings.ResultsSignificant differences were demonstrated, both at the level of individual delusions and in the nature and overall pattern of such delusions. There were also differences between diagnostic groups in the choice of body parts involved. Among male patients there were significant differences in laterality between the groups, with schizophrenic subjects locating abnormal phenomena principally on the left and depressive subjects on the right. A provisional taxonomy of bodily delusions was developed.ConclusionPhenomenological differences between the psychoses were demonstrated and the results offer some support for current hypotheses of localisation of brain dysfunction in the psychotic illnesses.


2014 ◽  
Vol 663 ◽  
pp. 395-399 ◽  
Author(s):  
Darliana Mohamad ◽  
Baba Md Deros ◽  
Dian Darina Indah Daruis ◽  
Nor Kamaliana Khamis ◽  
Nurul Hidayah Md Tahir

Motorcyclists are road users that highly exposed to hand-arm vibration that may contribute to body discomfort and fatigue that eventually will lead to road accidents and injuries. The two main objectives of this study are to identify the body parts that experience discomfort among motorcyclist and to understand the vibration exposure effect on different road types. In this study, two research methodologies were used; first, a survey questionnaire of 100 motorcyclists and second, an experimental study on hand-arm vibration (HAV) measurement exposed on motorcyclist using accelerometer mounted on the right side handlebars of the motorcycle. Two male respondents with a different weight range, 45-65 kg and >70 kg are selected for this experiment. The experiment was conducted on two different types of roads: tarmac road and pave road within a speed limit of 20-40 m/s2. Results of the study showed that the motorcyclist usually experienced body discomfort at lower back, upper back, wrist, buttock and neck area. The root-mean-square (r.m.s) frequency-weighted acceleration on the handlebars of the motorcycles was in the range of 0.07 m/s r.m.s for the tarmac road and 0.42 m/s r.m.s for the pave road. This value shows that different road type is affecting the vibration exposed to the motorcyclist. Clearly there’s a vibration felt by the motorcyclist but not on the degree of causing pain but a prolonged exposure to this vibration may induce discomfort and injuries.


Sign in / Sign up

Export Citation Format

Share Document