scholarly journals Age-dependent alteration of antioxidant defense system in hypertensive and type-2 diabetes patients

Author(s):  
Stanley IR Okoduwa ◽  
Ismaila A Umar ◽  
Sani Ibrahim ◽  
Fatima Bello ◽  
Nathan Habila
Diabetes ◽  
2012 ◽  
Vol 61 (10) ◽  
pp. 2652-2652
Author(s):  
C. Scheede-Bergdahl ◽  
M. Penkowa ◽  
J. Hidalgo ◽  
D. Olsen ◽  
P. Schjerling ◽  
...  

2015 ◽  
Vol 61 (6) ◽  
pp. 760-764
Author(s):  
N.P. Mikaelyan ◽  
A.A. Terentev ◽  
K.H. Nguen ◽  
A.V. Mikaelyan ◽  
S.A. Novikova

Obesity and type 2 diabetes (DM2) in women are accompanied by atherogenic dyslipidemia, with the activation of lipid peroxidation (LPO), as well as disturbances in the antioxidant defense system (ADS). DM2 due to imbalance in LPO-ADS is accompanied by a high concentration of LPO products, decreased parameters of antioxidant systems and timpaired utilization of glucose by cells. The results obtained in this study suggest an important role of fatty acids and their metabolites in the pathogenesis of obesity and DM2, which should be taken into consideration during design and selection of appropriate preventive and therapeutic measures aimed at prevention or elimination of the violations.


Redox Report ◽  
2013 ◽  
Vol 18 (2) ◽  
pp. 56-62 ◽  
Author(s):  
Octavian Savu ◽  
Ovidiu Marius Bradescu ◽  
Cristian Serafinceanu ◽  
Liviu Iosif ◽  
Constantin Ionescu Tirgoviste ◽  
...  

2020 ◽  
Vol 11 (1) ◽  
pp. 7-10
Author(s):  
Khadiza Begum ◽  
Fahmida Islam ◽  
Farjana Aktar ◽  
Murshida Aziz ◽  
Tohfa E Ayub Tahiya

Background: In recent times much is talked about of serum ferritin, an acute phase reactant a marker of iron stores in the body and its association with diabetes mellitus. Studies implicate that increased body iron stores and subclinical hemochromatosis has been associated with the development of glucose intolerance, type 2 diabetes and its micro as well as macrovascular complications. Material & Methods: This study was carried out to examine and to observe for any relationship between serum ferritin with Type 2 diabetes mellitus. Our study populations were included 163. Among them 81 type 2 diabetes patients as a case (M=49,F=32, mean 44.68 age in years)and 82 normal healthy individual as a control ( M=35, F=47 , mean 34.71 in years). Results: Majority were healthy outpatients who had come for regular checkup and were matched with controls. Serum ferritin and FBS were estimated and other investigations. Results showed that although Serum ferritin was in the normal range value it was increased in type 2 diabetes patients than in controls and was statistically significant, we did get a positive correlation with duration of diabetes. It can be concluded that there were positive associations between serum ferritin and FBG, age, sex among study groups. Conclusion: In conclusion our study shows that there is significant correlation between increased serum ferritin in diabetes compared to individuals with normal blood sugars in this part and hyper ferritinemia may be one of the causes for development of insulin resistance before overt diabetes. Anwer Khan Modern Medical College Journal Vol. 11, No. 1: Jan 2020, P 7-10


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