scholarly journals The effect of dietary intake of antioxidant micronutrients on burn wound healing: a study in a tertiary health institution in a developing country

2015 ◽  
Vol 3 ◽  
pp. 1-7 ◽  
Author(s):  
Mary Adjepong ◽  
Pius Agbenorku ◽  
Patricia Brown ◽  
Ibok Oduro

Abstract Background Burn injury results in emotional stress affecting dietary intake and antioxidant micronutrient intake, which is known to have effects on recovery outcomes. The study aimed to assess dietary intake of antioxidant micronutrients and recovery outcomes of burn patients. Methods Questionnaires were administered to 40 burn patients at Komfo Anokye Teaching Hospital (Ghana) from January 1, 2014 to May 30, 2014. The data taken include anthropometric measurements and dietary assessment. Their nutrient intakes were assessed with the Nutrient Analysis Template. The average intakes were compared to the recommended daily allowance. Assessment of recovery was based on records of wound healing assessments and infection rates from the health practitioners. Results A cross-sectional study of 40 patients revealed an average total burn surface area (TBSA) of 31.4 %, where 70.0, 35.0, 75.0, 52.5, 12.5 and 32.5 % patients were deficient in vitamins A, C and E, zinc, copper and selenium, respectively and adequate amounts of vitamin C intake were related with significantly better wound healing progress. Positive wound healing outcomes were observed for patients with adequate vitamins A and E and zinc intake. Less infection presented among patients with adequate amount of vitamins A and C and zinc, but this was not observed for patients with adequate vitamin E, copper and selenium. Conclusions Most burn patients did not meet their dietary requirements for antioxidant micronutrients and this was due to meals not tailored to suit individual requirements. Adequacy of the antioxidants especially vitamin C resulted in positive wound healing outcomes. Hence, there is need for planned well-balanced meals of high vitamin C.

2020 ◽  
Vol 7 (4) ◽  
pp. 1061
Author(s):  
Paritoshsingh B. Thakur ◽  
T. Ramachandrudu ◽  
Anant Arunrao Takalkar

Background: Worldwide, burn injury is a problem and cause intense pain, biological dressings like collagen as it forms physiological interface prevents infection effective for burn wound healing. The objective of the study was to study of collagen dressing versus conventional dressings in burns at tertiary health care centre.Methods: This was a cross sectional study carried out in the Department of Surgery during September 2018 to September 2019. Out of 50 patients, 25 were enrolled to collagen treatment group (group A) and remaining into conventional treatment group i.e. (group B). The statistical analysis was done by unpaired t-test and chi-square test.Results: Average less time required for granulation tissue to appear p<0.001, df=48, t=4.56); average less time requires for sterile wound swab culture (weeks) (p<0.05, df=48, t=3.45); less discomfort score (0-10) (p<0.001, df=48, t=6.78); less dressing removal pain score (0-10) (p<0.0001, df=48, t=9.87); less average time required for complete healing (days ) (p<0.001, df=48, t=7.79).Conclusions: It can be concluded that collagen dressings were superior to conventional dressing in wound healing of burns.


2020 ◽  
Vol 20 (1) ◽  
pp. 49-55
Author(s):  
Azam Molapour ◽  
Amir Peymani ◽  
Parvaneh Saffarain ◽  
Narges Habibollah-Pourzereshki ◽  
Pooya Rashvand

Introduction: Plasmid-induced quinolone resistance has raised a great concern in the treatment of serious infections worldwide. The aims of this study were to determine the antibiotic susceptibility, the frequency of qepA, aac(6')-Ib and qnr genes by PCR and sequencing, and typing of the resistant isolates using repetitive extragenic palindromic sequence-based PCR (REPPCR) in Pseudomonas aeruginosa isolated from burn wound infections. Methods: In the current cross-sectional study, 149 P. aeruginosa were isolated from the burn wound samples of patients admitted to Motahari hospital in Tehran, Iran, from February to December 2016. The bacterial isolates were identified using standard laboratory methods and their antibiotic susceptibility to quinolones was evaluated using the standard Kirby-Bauer method, according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. The presence of aac(6')-Ib, qepA, qnrA, qnrB4, qnrB and qnrS genes was assessed using PCR and sequencing methods and clonal relationship of the resistant isolates was evaluated using REP-PCR method. Results: All (100%) isolates showed complete resistance to used quinolone compounds in this study. The qnr and qepA genes were not found, but all (100%) isolates were positive for the presence of aac(6')-Ib gene and the sequencing revealed that all (100%) belong to the aac(6')-Ib-cr variant. REP-PCR showed that the studied isolates belonged to three distinct clones of A (77.9%), B (18.1%), and C (4%). Conclusion: The findings of the present study indicated the presence of aac(6')-Ib-cr variant and lack of the contribution of qnr and qepA in the emergence of resistance to quinolones in P. aeruginosa isolated from burn patients. Considering the importance of clonal spread of these resistant isolates and their significant role in the development of clinical infections, especially in patients with burns, more attention should be paid to the prevention of the dissemination of these resistant isolates.


2021 ◽  
Vol 8 (1) ◽  
pp. 15-20
Author(s):  
Gammaditya Adhibarata Winarno ◽  
Aditya Wardhana ◽  
Sanjaya Faisal Tanjunga ◽  
A. S Augiani ◽  
An’umillah Arini Zidna

Introduction: Early tangential excision (TE) and split-thickness skin graft (STSG) have increased the outcome in burn patients treated at specialized burn centers. This study was conducted to compare the length of stay (LOS) in burn patients undergoing early TE & STSG and delayed TE & STSG. Method: This is a retrospective cross-sectional study including 42 patients with varied burn degrees, and TBSA admitted to Jakarta Islamic Hospital Cempaka Putih (JIHCP) Burn Unit. Patients were assigned to two study groups, the early TE & STSG group including 32 patients and the delayed TE & STSG group including 10 patients. All data were collected from the medical record and compared between two study groups. Result: The mean of LOS in a group with early TE & STSG was shorter (9.81±6.41 days) than LOS in the delayed TE & STSG group (15.80±5.67 days). The data of LOS between these groups were compared using an independent T-test. The LOS in the early TE & STSG group was significantly shorter than the delayed TE & STSG group (p=0.012). Conclusion: In patients with burn injuries, early TE & STSG is associated with a shorter length of stay than the delayed TE & STSG. Our study indicates that early excision within five days after burn injury is optimal to reduce the length of stay in burn patients.


2014 ◽  
Vol 11 (1) ◽  
pp. 12
Author(s):  
Fatimah Az-zahra ◽  
Dedy Nurwahid ◽  
Retno Pangastuti

Background: Trend of gout arthritis prevalence is increasing every year. Obesity, high purine diet, especially from an animal source, are some risk factors for recurrent gout attacks.Objective: To evaluate the relationship between diet, obesity, and frequency of gout flares in gout arthritis patients.Method: This study was a cross-sectional study with patients from RSUP Dr. Sardjito, RSUD Wirosaban, RSUD Panembahan Senopati that ever diagnosed as gout arthritis within February 2010 - February 2012 which can be seen in the medical record and live in Special District of Yogyakarta with the full address provided, as the respondents of this study. The home visit was done for dietary assessment, waist circumference measurement, and interviewing the respondent about gout flares frequency during the last year.Results: Vitamin C consumption in the 1st and 2nd tertiles increase the odds to have any gout flare (OR=5.5; 95% CI: 1.08-27.77 and OR=1.5; 95% CI: 0.29-7.35, respectively). Obesity tends to increase the odds of having any gout flares up to 1.4 times (95% CI: 0,38-5,25).Conclusion: Low consumption of vitamin C significantly increases the odds of having any gout flares. The odds is also higher in patients with obesity, though this relationship is statistically insignificant.


2020 ◽  
Author(s):  
Seyedeh Forough Sajjadi ◽  
Atieh Mirzababaei ◽  
Afsoun Abdollahi ◽  
Farideh Shiraseb ◽  
Khadijeh Mirzaei

Abstract Background: The double burden of malnutrition is an emerging public health concern nowadays which a correlation with Obesity. The aim of this study was to examine the relationship between resting metabolic rate (RMR) and dietary intake of zinc, vitamin C, and riboflavin based on Nutrient Adequacy Ratios (NAR) in overweight and obese women.Methods: We enrolled 293 overweight and obese women in this cross-sectional study. BMI, body fat mass, fat-free mass, insulin level were assessed. RMR was measured using indirect calorimetry. NAR was measured by calculating the ratio of daily individual intakes to the standard recommended amounts.Results: the RMR/FFM showed a significant association with riboflavin (β=1.59; 95% CI: 1.04-23.26, P=0.04) and zinc (β=0.78; 95% CI: 1.04-4.61, P=0.03) in the crude model. Moreover, differences in vitamin C and RMR/FFM was marginal significant (β=0.75; 95% CI: 0.95-4.77, P=0.06). After adjust for confounders the riboflavin association change to marginal significance (β=1.52; 95% CI: 0.91-23.04, P=0.06). After controlling for potential confounders, the associations change between zinc and RMR/FFM (β=0.66; 95% CI: 0.78-4.86, P=0.15) and between RMR/FFM and vitamin C (β=0.48; 95% CI: 0.66-3.96, P=0.28).Conclusion: Our study showed a significant association between dietary intake of zinc, riboflavin, and vitamin C and change in RMR/FFM in overweight and obese women.


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Seyedeh Forough Sajjadi ◽  
Atieh Mirzababaei ◽  
Afsoun Abdollahi ◽  
Farideh Shiraseb ◽  
Khadijeh Mirzaei

Abstract Objective The double burden of malnutrition is an emerging public health concern nowadays which a correlation with obesity. This study aimed to examine the relationship between resting metabolic rate (RMR) and dietary intake of zinc, vitamin C, and riboflavin in overweight and obese women. Results The RMR/FFM showed a significant association with riboflavin (β = 1.59; 95% CI 1.04–23.26, P = 0.04) and zinc (β = 0.78; 95% CI 1.04–4.61, P = 0.03) in the crude model. Moreover, differences in vitamin C and RMR/FFM was marginal significant (β = 0.75; 95% CI 0.95–4.77, P = 0.06). After adjusting for confounders the riboflavin association change to marginal significance (β = 1.52; 95% CI 0.91–23.04, P = 0.06). After controlling for potential confounders, the associations change between zinc and RMR/FFM (β = 0.66; 95% CI 0.78–4.86, P = 0.15) and between RMR/FFM and vitamin C (β = 0.48; 95% CI 0.66–3.96, P = 0.28). Our study showed a significant association between dietary intake of zinc, riboflavin, and vitamin C and change in RMR/FFM in overweight and obese women.


2020 ◽  
Author(s):  
Seyedeh Forough Sajjadi ◽  
Atieh Mirzababaei ◽  
Afsoun Abdollahi ◽  
Farideh Shiraseb ◽  
Khadijeh - Mirzaei

Abstract Background: The double burden of malnutrition is an emerging public health concern nowadays which a correlation with Obesity. The aim of this study was to examine the relationship between resting metabolic rate (RMR) and dietary intake of zinc, vitamin C, and riboflavin based on Nutrient Adequacy Ratios (NAR) in overweight and obese women.Methods: We enrolled 293 overweight and obese women in this cross-sectional study. BMI, body fat mass, fat-free mass, insulin level were assessed. RMR was measured using indirect calorimetry. NAR was measured by calculating the ratio of daily individual intakes to the standard recommended amounts.Results: the RMR/FFM showed a significant association with riboflavin (β=1.59; 95% CI: 1.04-23.26, P=0.04) and zinc (β=0.78; 95% CI: 1.04-4.61, P=0.03) in the crude model. Moreover, differences in vitamin C and RMR/FFM was marginal significant (β=0.75; 95% CI: 0.95-4.77, P=0.06). After adjust for confounders the riboflavin association change to marginal significance (β=1.52; 95% CI: 0.91-23.04, P=0.06). After controlling for potential confounders, the associations change between zinc and RMR/FFM (β=0.66; 95% CI: 0.78-4.86, P=0.15) and between RMR/FFM and vitamin C (β=0.48; 95% CI: 0.66-3.96, P=0.28).Conclusion: Our study showed a significant association between dietary intake of zinc, riboflavin, and vitamin C and change in RMR/FFM in overweight and obese women.


2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 225-225
Author(s):  
Zhongyu Li ◽  
Ai Zhao ◽  
Yumei Zhang

Abstract Objectives Over the past decades, social changes and rapid economic development had significantly impacted people's lifestyle and physical health in China. This study aimed to examine nutrition and diet-related perceptions, knowledge, and concerns for chronic diseases as well as their relationships with dietary intake in the general Chinese population. Methods A health survey was conducted among 1708 participants living in urban areas in eight cities in mainland China in 2016. Food frequency questionnaire and a 24-hour recall were used for dietary assessment. The intake of nutrients was estimated based on the Chinese food database. Non-proportional odds ordinal and multi-nominal regression models were performed on Stata 15.1 to analyze the associations. Results Participants (66% female, mean age: 50.6 y-o) consumed, on average, 33.4%, 14%, and 52% of calories from fat, protein, and carbohydrate respectively. 42.9% of the participants perceived low fruits and vegetable intake as their major dietary problem. And the average intake of dietary fiber is 12.5 grams in the study population. Total of 57.5% of the participants have overweight or obesity (OWOB) and 34.4% self-reported at least one chronic disease. People who were older, OWOB, more educated, or have reported any chronic disease were more likely to be more concerned about their health. 45% – 50% of participants indicated a strong belief that an improved diet can benefit the prognosis of Type II diabetes, hypertension, and hyperlipidemia. Higher education, being younger (aged 18–33 y-o), and never smokers were associated with stronger beliefs. After adjusting for age, gender, income, education, BMI, and total energy intake, people from the highest quantile of belief scores ate more protein (β = 4.1, 95% CI: 0.8, 7.4), and have lower sodium to potassium ratio (β = –0.6, 95% CI: –0.9, –0.2) in their diets compared to those from the lowest quantile. Conclusions Factors such as age, education, and health status influence people's perception of nutrition and disease, which contribute to the difference in dietary intake. This study provided insights into factors that should be taken into consideration when designing and implementing nutritional education and interventions targeting the Chinese population. Funding Sources National key research and development projects YFD0400602.


2021 ◽  
Author(s):  
Seyedeh Forough Sajjadi ◽  
Atieh Mirzababaei ◽  
Afsoun Abdollahi ◽  
Farideh Shiraseb ◽  
Khadijeh Mirzaei

Abstract Objective: The double burden of malnutrition is an emerging public health concern nowadays which a correlation with Obesity. This study aimed to examine the relationship between resting metabolic rate (RMR) and dietary intake of zinc, vitamin C, and riboflavin in overweight and obese women.Results: the RMR/FFM showed a significant association with riboflavin (β=1.59; 95% CI: 1.04-23.26, P=0.04) and zinc (β=0.78; 95% CI: 1.04-4.61, P=0.03) in the crude model. Moreover, differences in vitamin C and RMR/FFM was marginal significant (β=0.75; 95% CI: 0.95-4.77, P=0.06). After adjusting for confounders the riboflavin association change to marginal significance (β=1.52; 95% CI: 0.91-23.04, P=0.06). After controlling for potential confounders, the associations change between zinc and RMR/FFM (β=0.66; 95% CI: 0.78-4.86, P=0.15) and between RMR/FFM and vitamin C (β=0.48; 95% CI: 0.66-3.96, P=0.28). Our study showed a significant association between dietary intake of zinc, riboflavin, and vitamin C and change in RMR/FFM in overweight and obese women.


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