scholarly journals Urinary albumin-to-creatinine ratio in decompensated liver cirrhosis among elderly Egyptian patients: a single-center experience

2021 ◽  
Vol 33 (1) ◽  
Author(s):  
Ahmed Abdelghani ◽  
Maha Hosam El-Din Ibrahim ◽  
Osama Mohamady Mohamed ◽  
Sobhi Eid Rizk ◽  
Rabab Mahmoud Ahmed

Abstract Background Hepatitis C virus and nonalcoholic steatohepatitis (NASH) are the most common causes of liver cirrhosis in Egypt. Increasing aging population is a worldwide issue, and societies are facing various problems, including long-term care for populations with a high prevalence of chronic conditions; hence, comprehensive geriatric assessment is important for determining patients’ mental health, functional capacity, and social circumstances. Normally, a small amount of protein (normal urinary albumin-to-creatinine ratio [UACR] < 30 mg/g) excreted in daily urine and excess amounts warrant further examination. The present study aims to evaluate the relationship between UACR and the severity of liver cirrhosis among 47 elderly patients (more than 65 years old) and 47 adult patients (control group) admitted to the hospital as well as the relationship between UACR and geriatric cognitive functions, functional capacity, depression, and nutritional status. Results The present study showed that the cognitive, functional, and nutritional status of patients aged 65 years old or more were significantly affected by the severity of liver disease. The investigators also reported a significant relationship between UACR and Child–Pugh score in the elderly patient group. No significant relationship was found between UACR and the cognitive, functional, mood, or nutritional status of the elderly age group. Conclusion Overall, UACR was correlated to the severity of liver disease among elderly patients compared with adult patients with liver cirrhosis.

2017 ◽  
Vol 1 (suppl_1) ◽  
pp. 387-387
Author(s):  
S. Kanwal ◽  
W. Qidwai ◽  
K. Nanji

2019 ◽  
Vol 70 (7) ◽  
pp. 2415-2419 ◽  
Author(s):  
Valeria Carmen Albu ◽  
Raluca Elena Sandu ◽  
Andreea Lili Barbulescu ◽  
Elena-Anca Tartea ◽  
Emilia Burada ◽  
...  

The aim of the study was to assess the correlations between the acute confusing syndrome and different comorbidities found in a group of 126 elderly patients with this diagnosis, who were admitted to the Neurology Clinic of the Neuropsychiatry Hospital of Craiova. The main syndromes highlighted at the neurological examination were confusing, pyramidal and vestibular syndromes. The acute confusing syndrome has a multifactorial etiology, due to the wide range of comorbidities encountered in elderly patients. In our study the most frequent comorbidities were cardiovascular pathology, diabetes mellitus, dyslipidemia, cerebrovascular renal, hepatic pathology.


2020 ◽  
Author(s):  
Takako Nagai ◽  
Koji Tanimoto ◽  
Yoshiaki Tomizuka ◽  
Hiroshi Uei ◽  
Masahiro Nagaoka

Abstract Background: Distal radius fractures (DRF) are common in the elderly and are typically caused falls. Malnutrition has also been identified as a poor prognostic factor in elderly patients with fractures. However, the relationship between nutritional status and subsequent falls and functional prognosis for DRF in the elderly is not clear. The aim of the present study was to investigate the association between nutritional status and functional prognosis in elderly patients with DRF. Methods: Study participants included 229 outpatients who required surgical treatment for DRF. The patients’ clinical information, including age, sex, body mass index, bone mineral density, Geriatric Nutritional Risk Index (GNRI), total number of drugs being treated with on admission, use of drugs for osteoporosis, comorbidity severity, the Barthel Index (BI), presence of subsequent falls, fracture type, postoperative follow-up period, and Mayo wrist score was reviewed. Subjects were further divided into two groups according to their GNRI: the malnutrition group and the normal group. Propensity score matching was used to confirm factors affecting the BI and subsequent falls. Results: Thirty-one patients (13.5%) presented with malnutrition before surgery for DRF. According to multiple liner regression analysis, the GNRI positively affected the efficiency of the BI (β = 0.392, 95% confidence interval [CI], 0.001 to 0.351, p = 0.039). Furthermore, on logistic regression analysis, subsequent falls were associated with serum albumin levels (odds ratio = 0.033, 95% CI, 0.002 to 0.477, p = 0.012). Conclusion: Malnutrition impaired improvement of activities of daily living (ADL) and increased the incidence of subsequent falls. Improvement of nutritional status before DRF surgery may further improve ADL and prevent falls.


2020 ◽  
Vol 7 (2) ◽  
pp. 32-45
Author(s):  
Mohamed Awadallah ◽  
Soad Abd Elhameed ◽  
Amira Hassaneen

2014 ◽  
pp. 1-5
Author(s):  
M.-M. DUBUC ◽  
S. BARBAT-ARTIGAS ◽  
A.D. KARELIS ◽  
M. AUBERTIN-LEHEUDRE

Background:Both the level of education and functional capacity seems to be associated with the levelof physical activity in the elderly. However, the relationship between the level of education and functionalcapacity in active elderly adults is poorly understood. Objective:To examine the association between the level ofeducation and the functional capacity profile of active elderly adults. Design:Cross-sectional. Participants:Onehundred and four elderly men and 198 postmenauposal women (mean age: 62.7 ± 7.6 years old) were recruitedamong registered members of the YMCAs of Montreal who practiced at least one hour of structured physicalactivity per week. Participants were then divided in two groups based on their level of education (the cut-offpoint was the high-school diploma). Measurements:Body composition (DXA), muscle strength (knee extensors,handgrip), estimated maximal oxygen consumption (2-km walk test), perceived health (SF-36) and functionalcapacity (timed up and go, alternate step and one-leg stance tests) were measured. The level of education of theparticipants was assessed by questionnaire. Results:Body composition was similar between groups. We observedthat all functional capacity tests as well as the global functional capacity score were significantly higher in themost educated group compared to the least educated group (p<0.05). In addition, the most educated group hadsignificantly higher levels of knee extensors strength, estimated maximal oxygen consumption and perception ofphysical functioning. Conclusions:A higher level of education was associated with a favourable functionalcapacity profile in our cohort of active elderly adults. However, the mechanism(s) which could mediate thisassociation remain(s) unknown.


2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Ayu Andini ◽  
Supriyadi Supriyadi

Year by year, the amount of elderly who lives at nursing home in Bali are increasingly. Most of them be carried to nursing home by their families with a reason that they are not able to take care of their elderly at home. It makes that there is a lot of elderly think negatively about the decision to put them at nursing home. Negative thinking makes them have a low self esteem. According to it, this study aiming to see the relationship positive thinking and self esteem to the elderly. This study is a correlational study between 84 elders who lives at nursing home in Bali as a subject. Method of data collection in this study is using questionnaires. The variable of positive thinking is measured positive thinking questionnaire, and the variable of self esteem is measured by self esteem questionnaire. Both of them are already valid and reliable. Positive thinking questionnaire consist of 22 items which validity range from 0,259 to 0,935 and the coefficient reliability is 0,944. Self esteem questionnaire consist of 23 items which validity range from 0,282 to 0,938 and the coefficient reliability is 0,959. The result of nonparametric Kendall’s Tau show that there is a significant relationship between positive thinking and self esteem (r=0,422 ; p=0,000). It that can be concluded that variable of positive thinking can explain the variable of self esteem in 17,8%. It can explain that the hypothesis  which stating that there is a relationship between positive thinking and self esteem to the elderly who lives at nursing home in Bali can be accepted. The other things that can explain about the relationship between positive thinking and self esteem are because the elderly able to; (1)accept themselves and their condition, (2) adapt with their environment, (3) see themselves positively, (4) show their power, (5) show their competence.   Keyword : positive thinking, self esteem, elderly, and nursing home


BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e039804
Author(s):  
Chen Huanan ◽  
Li Sangsang ◽  
Adwoa Nyantakyiwaa Amoah ◽  
Bo Yacong ◽  
Chen Xuejiao ◽  
...  

ObjectiveNon-alcoholic fatty liver disease (NAFLD) is one of the major causes of liver-related diseases but relationship between triglyceride glucose (TyG) and NAFLD in the elderly is not reported yet. In this study, we investigated the role of TyG index for predicting the incidence of NAFLD in the elderly.Design and settingThis is a prospective cohort study in Henan, China, from 2011 to 2018.Participants and methodsIn total, 46 693 elderly who participated in a routine physical examination programme from 2011 to 2018 were included in this study. TyG index was calculated as ln (fasting triglyceride (mg/dL)×fasting plasma glucose (mg/dL)/2), while NAFLD was defined as hepatic steatosis after excluding other causes based on the results of abdominal ultrasonography; Cox regression model was performed to explore the relationship between TyG index and NAFLD. Also, mediation effect was used to analyse the role of the TyG index in WHtR (waist-to-height ratio) and NAFLD.ResultsDuring the 149 041 person-years follow-up, a total of 5660 NAFLD events occurred (3.80/100 person-years). After adjusting for potential confounding factors, quartiles 4 of TyG index significantly increased the incidence of NAFLD compared with quartile 1, the HRs and 95% CI were 1.314 (1.234 to 1.457). In addition, TyG index played a partial mediating role in the relationship between WHtR and NAFLD and indirect effect was 1.009 (1.006 to 1.011).ConclusionHigher TyG index was associated with higher risk of NAFLD in the aged, and therefore, TyG index may be a novel predictor for incidence of NAFLD. Further, regular examination and evaluation of the TyG index might be useful for controlling the occurrence of NAFLD.


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