Increased rate of psychosis among African–Caribbeans in Britain is not due to an excess of pregnancy and birth complications

1997 ◽  
Vol 171 (2) ◽  
pp. 145-147 ◽  
Author(s):  
G. Hutchinson ◽  
N. Takei ◽  
D. Bhugra ◽  
T. A. Fahy ◽  
C. Gilvarry ◽  
...  
Keyword(s):  
Odds Ratio ◽  
First Generation ◽  
Second Generation ◽  
Psychotic Illness ◽  
Comparable Group ◽  
Birth Complications ◽  
African Caribbean ◽  
History Of ◽  
First And Second Generation ◽  
Pregnancy And Birth

BackgroundIt has been suggested that the increased rate of psychotic illness among African–Caribbeans living in Britain is due to an excess of pregnancy and birth complications (PBCs).MethodWe therefore compared the frequency of PBCs in a group of White psychotic patients (n=103) and a comparable group of patients of African–Caribbean origin (n=61); the latter consisted of 30 first-generation (born in the Caribbean) and 31 second-generation (born in Britain) individuals.ResultsWhite psychotic patients were more than twice as likely to have a history of PBCs as their African–Caribbean counterparts (odds ratio=2.34, 95% confidence interval (CI) 0.88–6.47, P=0.062). The same trend was observed among patients with a DSM–III diagnosis of schizophrenia (odds ratio=l.65, 95% CI 0.56–4.97, P=0.32). The rate of PBCs was similar among the first- and second-generation Caribbean psychotic patients.ConclusionsThe increased rate of psychotic illness that has been reported among the African–Caribbean population in Britain is not due to an increased prevalence of PBCs.

scholarly journals The ages of Galactic globular clusters in the context of self-enrichment

2008 ◽  
Vol 4 (S258) ◽  
pp. 265-274 ◽  
Author(s):  
T. Decressin ◽  
H. Baumgardt ◽  
P. Kroupa ◽  
G. Meynet ◽  
C. Charbonnel
Keyword(s):  
Globular Clusters ◽  
First Generation ◽  
Second Generation ◽  
Age Determination ◽  
Dynamical Evolution ◽  
Low Velocity ◽  
Tidal Forces ◽  
History Of ◽  
First And Second Generation

AbstractA significant fraction of stars in globular clusters (about 70%-85%) exhibit peculiar chemical patterns, with strong abundance variations in light elements along with constant abundances in heavy elements. These abundance anomalies can be created in the H-burning core of a first generation of fast-rotating massive stars, and the corresponding elements are conveyed to the stellar surface thanks to rotational induced mixing. If the rotation of the stars is fast enough, this material is ejected at low velocity through a mechanical wind at the equator. It then pollutes the interstellar medium (ISM) from which a second generation of chemically anomalous stars can be formed. The proportion of anomalous stars to normal stars observed today depends on at least two quantities: (1) the number of polluter stars; (2) the dynamical history of the cluster, which may lose different proportions of first- and second-generation stars during its lifetime. Here we estimate these proportions, based on dynamical models for globular clusters. When internal dynamical evolution and dissolution due to tidal forces are accounted for, starting from an initial fraction of anomalous stars of 10% produces a present-day fraction of about 25%, still too small with respect to the observed 70-85%. In the case of gas expulsion by supernovae, a much higher fraction is expected to be produced. In this paper we also address the question of the evolution of the second-generation stars that are He-rich, and deduce consequences for the age determination of globular clusters.

scholarly journals Second-Generation Antipsychotics and Extrapyramidal Adverse Effects

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Nevena Divac ◽  
Milica Prostran ◽  
Igor Jakovcevski ◽  
Natasa Cerovac
Keyword(s):  
Adverse Effects ◽  
First Generation ◽  
Second Generation ◽  
Great Expectations ◽  
Extrapyramidal Syndrome ◽  
Generation Agent ◽  
Second Generation Antipsychotics ◽  
History Of ◽  
High Doses ◽  
First And Second Generation

Antipsychotic-induced extrapyramidal adverse effects are well recognized in the context of first-generation antipsychotic drugs. However, the introduction of second-generation antipsychotics, with atypical mechanism of action, especially lower dopamine receptors affinity, was met with great expectations among clinicians regarding their potentially lower propensity to cause extrapyramidal syndrome. This review gives a brief summary of the recent literature relevant to second-generation antipsychotics and extrapyramidal syndrome. Numerous studies have examined the incidence and severity of extrapyramidal syndrome with first- and second-generation antipsychotics. The majority of these studies clearly indicate that extrapyramidal syndrome does occur with second-generation agents, though in lower rates in comparison with first generation. Risk factors are the choice of a particular second-generation agent (with clozapine carrying the lowest risk and risperidone the highest), high doses, history of previous extrapyramidal symptoms, and comorbidity. Also, in comparative studies, the choice of a first-generation comparator significantly influences the results. Extrapyramidal syndrome remains clinically important even in the era of second-generation antipsychotics. The incidence and severity of extrapyramidal syndrome differ amongst these antipsychotics, but the fact is that these drugs have not lived up to the expectation regarding their tolerability.

Assimilation of the Puerto Ricans on the Mainland

1968 ◽  
Vol 2 (2) ◽  
pp. 21-39
Author(s):  
John J. Macisco
Keyword(s):  
United States ◽  
First Generation ◽  
Second Generation ◽  
Puerto Ricans ◽  
The United States ◽  
Social Scientists ◽  
First Marriage ◽  
Labor Force Status ◽  
Age At First Marriage ◽  
First And Second Generation

Social scientists have repeatedly tried to specify the process whereby assimilation takes place. This article points out the value of socio-demographic analysis in the study of assimilation, by describing the characteristics of Puerto Ricans on the United States mainland. In order to assess the direction of change between the first and second generation Puerto Ricans, data for the total United States population are also presented. Most of the data are drawn from the 1960 Census. First generation Puerto Ricans are compared with the second generation along the following dimensions: age, education, labor force status, income, occupation, age at first marriage, percent outgroup marriage and fertility. The Author concludes that second generation Puerto Ricans are moving in the direction of total United States averages.

scholarly journals Why do first and second-generation young migrants volunteer? The Migrant Volunteerism Motivation Model (MVMM)

2019 ◽  
Vol 7 (2) ◽  
pp. 1089-1107 ◽  
Author(s):  
Sara Alfieri ◽  
Daniela Marzana ◽  
Sara Martinez Damia
Keyword(s):  
Transition To Adulthood ◽  
Process Model ◽  
First Generation ◽  
Second Generation ◽  
Maintenance Phase ◽  
Structured Interviews ◽  
Sub Saharan ◽  
Italian Context ◽  
First And Second Generation ◽  
Motivation Model

The following study aims at inquiring into the motivations behind young migrants’ volunteerism in civic organizations in Italy, namely in starting and maintaining their engagement (preliminary vs. maintenance phase). The term “young migrants” refers to first and second generation of migrants who deal with two challenges: the transition to adulthood and the acquisition of a cultural identity. We conducted semi-structured interviews with 37 Sub-Saharan young migrants living in Italy (18-32 years old), 19 of first generation (1G) and 18 of second generation (2G). The Omoto and Snyder’s Volunteer Process Model (VPM, 1995) was used as an underpinning theoretical framework and a guide for the interpretations of the results. The findings indicate that a) motivations included in the VPM are also found for young migrants, b) some of these motivations take particular meaning for young migrants, c) some motivations are not included in the VPM and are specific of this sample. We named these last motivations: social norms, advocacy and ethno-cultural. In addition, some considerations may be advanced regarding the generation and the phase of motivation: 1G migrants are particularly moved by the importance of integration in the Italian context and by the promotion of their ethnic group while 2G migrants reported mostly the desire to understand their roots. The values, the concern for the community and the longing to develop relationships are the motivations for which all young migrants continue to volunteer; however, 1G migrants are also sustained by advocacy and ethno-cultural motivations. Implications and future directions are discussed.

scholarly journals The performance and genetic variation of first and second generation tropical alfalfa (Medicago sativa)

2021 ◽  
Vol 22 (6) ◽  
Author(s):  
Bambang Suwignyo ◽  
LUKMANA ARIFIN ◽  
NAFIATUL UMAMI ◽  
MUHLISIN MUHLISIN ◽  
BAMBANG SUHARTANTO
Keyword(s):  
Organic Matter ◽  
Genetic Variation ◽  
Medicago Sativa ◽  
Crude Protein ◽  
Dry Matter ◽  
First Generation ◽  
Second Generation ◽  
Seed Viability ◽  
Nutrient Content ◽  
First And Second Generation

Abstract. Suwignyo B, Arifin L, Umami N, Muhlisin, Suhartanto B. 2021. The performance and genetic variation of first and second generation tropical alfalfa (Medicago sativa). Biodiversitas 22: 3265-3270. This study aimed to compare the growth performance, nutrient content, seed viability, and genetic variation of first- and second-generation alfalfa (Medicago sativa L.). First and second-generation alfalfa seeds were obtained from the Forage and Pasture Science Laboratory, Department of Animal Nutrition and Feed Science, Faculty of Animal Science, Universitas Gadjah Mada (UGM), Yogyakarta, Indonesia. First generation alfalfa (F1) seeds were obtained from cross breeding of two different parental alfalfa varieties, namely, Canadian and local. The second-generation (F2) seeds were obtained from plants of the first-generation alfalfa (F1). A randomized design experiment was conducted using the two types of alfalfa (first- and second generation). Alfalfa from Canada as female parent was used as the baseline in the genetic masker test. Seeds were planted in a polybag, watered twice a day, and received 12 hours of daylight and 4 hours of artificial light. Plants were then harvested 8 weeks after planting by cutting the plant canopy. Genetic variation was examined using the Inter Simple Sequence Repeat (ISSR) method followed by descriptive analysis. Germination, plant height, dry matter content, organic matter, and crude protein were assessed as variables using a Student’s T-test. Our results showed that germination, plant height, leaf color, and nutrient content (dry matter, organic matter, and crude protein) of the first- and second-generation alfalfa plants were not significantly different. However, the second-generation alfalfa demonstrated better seed viability than the first generation plants, then it can be categorized as a new genotype (tropical alfalfa) based on genetic variation analysis.

Differential Impairments in Incentive Learning Caused by First‐ and Second‐ Generation Antipsychotic Drugs

2016 ◽  
Author(s):  
Matthew Florczynski
Keyword(s):  
Neural Control ◽  
First Generation ◽  
Antipsychotic Drugs ◽  
Second Generation ◽  
Operant Chamber ◽  
Incentive Learning ◽  
Dopamine Receptor Antagonists ◽  
Natural Response ◽  
Second Generation Antipsychotic ◽  
First And Second Generation

Schizophrenia is a neuropsychiatric disorder characterized by increased function of dopamine in the brain.  Dopamine release is a natural response to reward.  It promotes incentive learning (IL), a process by which neutral stimuli acquire the ability to elicit approach and other responses.  A recent model characterizes dopamine‐mediated IL as a progressive process with early and late stages accompanied by a shift in neural control from the nucleus accumbens (NAc) to the dorsolateral striatum (DLS).  A parallel can be drawn to differences in regionally specific neural responses generated by first‐ and second‐generation antipsychotic drugs (APDs) used to treat schizophrenia.  APDs are dopamine receptor antagonists, but first‐generation APDs affect the NAc and DLS while second‐generation APDs affect primarily the NAc.  We compared the effects of APDs on IL. Rats (N = 48) were trained to press a lever forfood pellets in an operant chamber.  Intraperitoneal injections (1 hr before testing) of the first‐generation APD haloperidol (0,0.05,0.10,0.20 mg/kg) or of the second‐generation APD risperidone (0,0.20,0.40,0.80 mg/kg) induced dose‐dependent suppression of lever pressing on days 1‐4, with the highest dose groups failing to demonstrate any evidence of previous learning on day 5 when tested drug‐free.  On days 16‐20 haloperidol induced a day‐to‐day suppression not seen with risperidone.  The results suggest that the effects of first‐ and second‐generation APDs on learning processes putatively mediated by the NAc and DLS can be differentiated experimentally.  The findings imply that APDs may differentially affect IL inpatients with schizophrenia.  

4.  Differential Impairments in Incentive Learning Caused by First‐ and Second‐ Generation Antipsychotic Drugs

2016 ◽  
Author(s):  
Matthew Florczynski
Keyword(s):  
Neural Control ◽  
First Generation ◽  
Antipsychotic Drugs ◽  
Second Generation ◽  
Operant Chamber ◽  
Incentive Learning ◽  
Dopamine Receptor Antagonists ◽  
Natural Response ◽  
Second Generation Antipsychotic ◽  
First And Second Generation

Schizophrenia is a neuropsychiatric disorder characterized by increased function of dopamine in the brain.  Dopamine release is a natural response to reward.  It promotes incentive learning (IL), a process by which neutral stimuli acquire the ability to elicit approach and other responses.  A recent model characterizes dopamine‐mediated IL as a progressive process with early and late stages accompanied by a shift in neural control from the nucleus accumbens (NAc) to the dorsolateral striatum (DLS).  A parallel can be drawn to differences in regionally specific neural responses generated by first‐ and second‐generation antipsychotic drugs (APDs) used to treat schizophrenia.  APDs are dopamine receptor antagonists, but first‐generation APDs affect the NAc and DLS while second‐generation APDs affect primarily the NAc.  We compared the effects of APDs on IL. Rats (N = 48) were trained to press a lever for food pellets in an operant chamber.  Intraperitoneal injections (1 hr before testing) of the first‐generation APD haloperidol (0,0.05,0.10,0.20 mg/kg) or of the second‐generation APD risperidone (0,0.20,0.40,0.80 mg/kg) induced dose‐dependent suppression of lever pressing on days 1‐4, with the highest dose groups failing to demonstrate any evidence of previous learning on day 5 when tested drug‐free.  On days 16‐20, haloperidol induced a day‐to‐day suppression not seen with risperidone.  The results suggest that the effects of first‐ and second‐generation APDs on learning processes putatively mediated by the NAc and DLS can be differentiated experimentally.  The findings imply that APDs may differentially affect IL inpatients with schizophrenia.

One person, three identities? Examining re-politicization of ethnic, national, and Australian identities among 1.5-generation Taiwanese immigrants in Australia

2020 ◽  
pp. 144078332093415
Author(s):  
Yao-Tai Li
Keyword(s):  
First Generation ◽  
Second Generation ◽  
Identity Negotiation ◽  
Generation 1.5 ◽  
The Political ◽  
Host Society ◽  
1.5 Generation ◽  
Ethnic Chinese ◽  
Second Generation Immigrants ◽  
First And Second Generation

Immigrants of the 1.5-generation (1.5-ers) differ from first- and second-generation immigrants because they are generally better immersed in the culture of the host society than the first generation; yet, compared to the second generation, they often have to renegotiate their identities in relation to parents, colleagues at work, and people in the host society during the processes of migration. Drawing on interview data from Taiwanese 1.5-ers in Australia, this article takes a further step and points out that in addition to the identity struggle between home and host country, Taiwanese 1.5-ers also identify as ethnic Chinese (Huaren) and constantly negotiate between these three identities (Huaren, Taiwanese, and Australian). This article argues that identity negotiation and hybridization is in nature a re-politicization process in which respondents are fully aware of the political meanings and power disparities of each identity. It is also a process whereby Taiwanese 1.5-ers mobilize, downplay, and hybridize specific identities based on time and context.

The role of style in the ethnolect: Style-shifting in the use of ethnolectal features in first- and second-generation speakers

2020 ◽  
Vol 24 (4) ◽  
pp. 861-880 ◽  
Author(s):  
Ksenia Gnevsheva
Keyword(s):  
Design Methodology ◽  
First Generation ◽  
Second Generation ◽  
The Other ◽  
Research Questions ◽  
Similarities And Differences ◽  
Style Shifting ◽  
Australian English ◽  
First And Second Generation

Aims and Objectives/Purpose/Research Questions: The paper aimed to investigate style-shifting in the use of ethnolectal features in first- and second- generation bilingual migrants. Design/Methodology/Approach: Three groups of speakers (first- and second-generation Russian–English bilinguals as well as monolingual Anglo Australians) were audio-recorded in three different styles (conversation, interview, and reading). Data and Analysis: Their production of the goose and trap vowels across the styles was analyzed quantitatively. Findings/Conclusions: Overall differences were found between the groups such that first- and second-generation speakers produced more Russian-like vowels compared to the monolinguals; with the biggest differences between the first-generation speakers and the other two groups. In terms of style-shifting, no significant differences were found in the monolingual speakers, and both first- and second-generation speakers were found to produce most Australian English-like vowels in the conversation style. At the same time, certain differences between the two bilingual groups surfaced, such as no significant differences in the first-generation speakers’ production of the goose vowel and in the vowels’ linguistic conditioning. Originality: Previous studies have compared ethnolects in the first- and second-generations of migrants and mainstream varieties in order to theorize ethnolect formation. Several studies have also investigated intraspeaker style-shifting between more ‘mainstream’ and more ‘ethnic’ in ethnolect speakers, but such style-shifting is rarely compared across generations. Significance/Implications: The similarities and differences between the two bilingual groups suggest that ethnolectal features may be originally derived from the community language but may be reallocated to other sociolinguistic meanings in the second generation.

Immigrant and second-generation Turkish entrepreneurs in Melbourne Australia

2015 ◽  
Vol 21 (2) ◽  
pp. 154-174 ◽  
Author(s):  
Yasemin Soydas ◽  
Torgeir Aleti
Keyword(s):  
First Generation ◽  
Second Generation ◽  
Government Support ◽  
Entrepreneurial Activity ◽  
Content Type ◽  
Positive Effects ◽  
Immigrant Entrepreneurs ◽  
Generation Immigrant ◽  
Business Establishment ◽  
First And Second Generation

Purpose – The purpose of this paper is to examine the key differences between first- and second-generation immigrant entrepreneurs in their path to entrepreneurship. The aim of the study is to better understand entrepreneurial motivations amongst immigrants by comparing first- and second-generation entrepreneurs in their motivation for business entry, reliance on co-ethnic market, use of social and financial capital, business planning and marketing practices. Design/methodology/approach – Using an interpretivist approach and a qualitative design, this study comprises 20 in-depth interviews with first- and second-generation Turkish entrepreneurs (TEs) in Melbourne, Australia. Turks in Australia were chosen because of their high level of entrepreneurial activity. In order to uncover deep-seeded motivations, participants were interviewed in a face-to-face format guided by a semi-structured interview guide. Findings – The second-generation TEs were distinctively different from their first-generation counterparts in motivation for business entry, business establishment and use of ethnicity. The analysis shows that although the generations differ in their approach to business establishment, they both appear to be drawn to entrepreneurship based on “pull factors”. This is in contrast with previous literature suggesting that first-generation immigrant entrepreneurs were motivated by “push factors”. Originality/value – This paper suggests that both first- and second-generation immigrant entrepreneurs are “pulled” into entrepreneurship voluntarily. While the first-generation entrepreneurs seem to be motivated/pulled by financial reasons, the second generation are motivated by opportunity recognition, status and ambition. Nevertheless, a lack of trust in government support agency is found within both generations. Thus, outreach activities towards entrepreneurial immigrant communities may have positive effects for the economy as well as in the integration of ethnic enclaves.

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