On the Differential Diagnosis of Manie - Depressive Insanity and Dementia Præcox. (Glasg. Med. Journ., vol. lxxx., Sept. 1913, pp. 185–192)

1916 ◽  
Vol 62 (258) ◽  
pp. 622-624
Author(s):  
Hubert J. Norman
Keyword(s):  
Mental Disorder ◽  
Underlying Disease ◽  
Dementia Praecox ◽  
Disease Category ◽  
General Acceptance ◽  
Manic Depressive ◽  
Disease Entities ◽  
The Individual ◽  
The Brain ◽  
Organic Change

“The terms manic-depressive insanity and dementia præcox were used by Kraepelin to designate two disease entities, which he considered were between them responsible for most of the states of mental disorder usually gathered together under the title, the psychoses.” The psychoses are something more than states of mental disorder, and something less than disease entities; they lie between them. Excitement, depression, delirium, and stupor are states of mental disorder which may arise during the course of many diseases, general paralysis, hysteria, epilepsy, the cerebropathies, constitutional and infectious diseases; but acute mania, acute melancholia, anergic stupor, delirious mania, are psychoses. They differ from a state of mental disorder in so far as they are self-sufficient, and are not the expression of an underlying disease; moreover, they run a fairly definite course, ending either in recovery or in dementia. The classifications of the psychoses have been unsatisfactory, and none of them has met with general acceptance. The most satisfactory method is that formulated by Kraepelin: and, in the opinion of Dr. Marshall, he “has done for the psychoses what Erb did for the amyotrophies.” He emphasised the importance of dementia as a termination of the psychoses, and gathered those which ended in dementia into one disease category, dementia præcox, and those which did not so end into another category, manic-depressive insanity. The fact that dementia occurred predicated an organic change in the brain, so that dementia præcox was an organic and manic-depressive a functional disease of the brain. Certain states of mental disorder are common to both conditions: yet there are symptoms which render it possible to distinguish between them. In dementia præcox there is “inco-ordination of the individual psychical processes”: manic-depressive insanity depends on “a change in the mutability of the individual psychical processes.” Normal mentality results from the co-ordinated action of the emotional, intellectual, and volitional processes, and is characterised by a certain congruity of thought and conduct. If there is inco-ordination of these fundamental processes, incongruity of thought and conduct results. The nature of the incongruity depends on the mental process mainly responsible for the incoordination. The symptoms may be for a time emotional, intellectual, or volitional.

The Genetic Origin of Dementia Præcox

1922 ◽  
Vol 68 (283) ◽  
pp. 333-347 ◽  
Author(s):  
Frederick W. Mott
Keyword(s):  
Mental Disorders ◽  
Partial Remission ◽  
Reproductive Organs ◽  
Interstitial Cells ◽  
Dementia Praecox ◽  
Genetic Origin ◽  
Partial Restoration ◽  
Manic Depressive ◽  
The Brain ◽  
Adolescent Period

Mr. President, Ladies and Gentlemen,—Last year I had the honour of delivering the Maudsley Lecture, and I brought forward a certain amount of evidence in favour of the genetic causation of dementia præcox. I have continued these investigations and published the results in papers entitled “Further Pathological Studies in Dementia Præcox, especially in Relation to the Interstitial Cells of Leydig,” Proc. Roy. Soc. Med., 1922, vol. xv (Section of Psychiatry), pp. 1–30; also “The Reproductive Organs in Relation to Mental Disorders,” Brit. Med. Journ., March 25, 1922. The former investigation included 27 cases of dementia præcox, the onset occurring in adolescence; also the results obtained in 9 cases of psychoses other than dementia præcox occurring in post-adolescence, and 4 cases of primary dementia, in which the demential symptoms came on in post-adolescence. From these investigations, and from others which I have been pursuing, I have come to the conclusion that it is better to speak of primary dementia, which may occur either in the pre-adolescent period, adolescence, or post-adolescence; moreover, I am of opinion that all the psychoses belong to one group and are genetic in origin. In those forms of psychoses in which recovery takes place—for example, confusional insanity or exhaustion psychosis, benign stupor, periodic insanity, or manic-depressive insanity—we may assume there is a suspension of neuronic function in the highest psychic level; but all these conditions I have found may end in a terminal dementia, in which the changes in the reproductive organs and in the brain do not differ from those met with in the primary dementia of adolescence, the dementia indicative of a suppression of function. In the primary dementias, naturally, the symptoms may be partially due to a suspension, and partially to a suppression of function, and I would explain partial remission of symptoms by a partial restoration of function in neurones in which the nuclear change was either not present or not advanced.

Psychic and Somatic Reactions to Subconvulsive and Convulsive Doses of Triazol

1939 ◽  
Vol 85 (357) ◽  
pp. 796-802
Author(s):  
John B. Dynes ◽  
Henry Tod
Keyword(s):  
Mental Disorders ◽  
Mental Disorder ◽  
Average Duration ◽  
Affective Response ◽  
Heterogeneous Group ◽  
Manic Depressive ◽  
Schizophrenic Patients ◽  
Schizophrenic Group ◽  
The Individual ◽  
Chronic Anxiety

This investigation attempts to determine what effect a sub-convulsive dose of triazol had on the individual patient as compared with a convulsive dose, and in addition to study and compare the reactions of a group of deteriorated schizophrenic patients with those of a heterogeneous group composed of mental disorders not schizophrenic. There were 12 patients in each group. The first group of schizophrenic patients was made up of individuals who showed marked emotional deterioration, with either a poverty of affective response or a definitely inappropriate affect. All these patients had had their mental disorder for many years. The average duration of the psychosis in the schizophrenic group was 9 years, and the average age of the group was 31 years. The heterogeneous group was composed of three patients classified as manic-depressive in the depressed phase, two depressed patients in a stuporous condition, three psychoneurotic patients with chronic anxiety states, and four with chronic obsessive states. The average age of the heterogeneous group was 33 years.

Cycloid Psychoses—Endogenous Psychoses which are Neither Schizophrenic Nor Manic-Depressive

1961 ◽  
Vol 107 (449) ◽  
pp. 633-648 ◽  
Author(s):  
Karl Leonhard
Keyword(s):  
Clinical Picture ◽  
World Wide ◽  
Dementia Praecox ◽  
Diagnostic Categories ◽  
Wide Acceptance ◽  
Manic Depressive ◽  
Cycloid Psychoses ◽  
Endogenous Psychoses ◽  
Disease Entities

Kraepelin's diagnostic classification of the endogenous psychoses received world-wide acceptance, but today it is generally considered to have failed and is at times rejected by some workers with a few scornful words. This is not due to Kraepelin's own work but is the result of the way in which his successors have used his concepts. Kraepelin himself was not satisfied with the rough division of the endogenous psychoses into the two forms of manic-depressive insanity and schizophrenia, or as he termed it, dementia praecox. He, in fact, never ceased trying to isolate more disease entities. Thus, for example, he differentiated a large number of special forms of schizophrenia. Although he defined the two major groups of endogenous psychoses, this did not mean that he limited the number of diagnostic categories. On the contrary, he investigated all special forms of mental illness very carefully. If he saw a clinical picture which was unknown to him he would say, “So far I do not know this clinical picture, we should describe it adequately, perhaps other cases will occur as well, which will allow the isolation of a characteristic clinical picture.”

Fit Vs Faint: Assessing Work Causation in “Idiopathic Fall” Cases

2014 ◽  
Vol 19 (5) ◽  
pp. 3-12
Author(s):  
Lorne Direnfeld ◽  
David B. Torrey ◽  
Jim Black ◽  
LuAnn Haley ◽  
Christopher R. Brigham
Keyword(s):  
Blood Flow ◽  
Electrical Activity ◽  
Loss Of Consciousness ◽  
Brain Electrical Activity ◽  
Medical Terminology ◽  
Scientific Analysis ◽  
Medical Causation ◽  
The Individual ◽  
The Brain ◽  
Current Science

Abstract When an individual falls due to a nonwork-related episode of dizziness, hits their head and sustains injury, do workers’ compensation laws consider such injuries to be compensable? Bearing in mind that each state makes its own laws, the answer depends on what caused the loss of consciousness, and the second asks specifically what happened in the fall that caused the injury? The first question speaks to medical causation, which applies scientific analysis to determine the cause of the problem. The second question addresses legal causation: Under what factual circumstances are injuries of this type potentially covered under the law? Much nuance attends this analysis. The authors discuss idiopathic falls, which in this context means “unique to the individual” as opposed to “of unknown cause,” which is the familiar medical terminology. The article presents three detailed case studies that describe falls that had their genesis in episodes of loss of consciousness, followed by analyses by lawyer or judge authors who address the issue of compensability, including three scenarios from Arizona, California, and Pennsylvania. A medical (scientific) analysis must be thorough and must determine the facts regarding the fall and what occurred: Was the fall due to a fit (eg, a seizure with loss of consciousness attributable to anormal brain electrical activity) or a faint (eg, loss of consciousness attributable to a decrease in blood flow to the brain? The evaluator should be able to fully explain the basis for the conclusions, including references to current science.

SAMUEL J. BROADS CONTRIBUTIONS TO THE ACCOUNTING PROFESSION

1996 ◽  
Vol 23 (2) ◽  
pp. 69-85 ◽  
Author(s):  
Gary John Previts ◽  
Thomas R. Robinson
Keyword(s):  
Self Regulation ◽  
Accounting Profession ◽  
General Acceptance ◽  
Accounting Principles ◽  
The Individual ◽  
Securities Laws ◽  
Analogous Reasoning ◽  
Independent Audit ◽  
Selection Of

In the decade following the passage of the Federal Securities Laws of 1933 and 1934, the reform of accounting and auditing practices directed authority for selection of accounting principles and auditing procedures away from the discretion of the individual accountant and auditor. Instead, a self-regulatory peer driven process to establish general acceptance for a more limited set of principles and procedures was being initiated. Two events which occurred in 1938 indelibly affected this process, the SEC's decision to issue Accounting Series Release No. 4, which empowered non-governmental entities as potential sources of authoritative support, and the McKesson & Robbins fraud which called into question the value of the independent audit and the role of external auditing at the very time a momentum had been established for self-regulation by the nascent and recently reunified accounting profession. The contributions of Samuel J. Broad in both the initiatives for self-regulation of accounting principles and of auditing procedures is examined in this paper. Further, several examples of Broad's rhetorical technique of employing analogous reasoning to facilitate dissemination of complex economic and accounting issues are examined.

Individual Uniqueness in the Neonatal Functional Connectome

2021 ◽  
Author(s):  
Qiushi Wang ◽  
Yuehua Xu ◽  
Tengda Zhao ◽  
Zhilei Xu ◽  
Yong He ◽  
...  
Keyword(s):  
Individual Differences ◽  
Individual Identification ◽  
Imaging Data ◽  
Functional Connectome ◽  
Middle Range ◽  
Human Connectome Project ◽  
The Individual ◽  
And Behavior ◽  
Identification Analysis ◽  
The Brain

Abstract The functional connectome is highly distinctive in adults and adolescents, underlying individual differences in cognition and behavior. However, it remains unknown whether the individual uniqueness of the functional connectome is present in neonates, who are far from mature. Here, we utilized the multiband resting-state functional magnetic resonance imaging data of 40 healthy neonates from the Developing Human Connectome Project and a split-half analysis approach to characterize the uniqueness of the functional connectome in the neonatal brain. Through functional connectome-based individual identification analysis, we found that all the neonates were correctly identified, with the most discriminative regions predominantly confined to the higher-order cortices (e.g., prefrontal and parietal regions). The connectivities with the highest contributions to individual uniqueness were primarily located between different functional systems, and the short- (0–30 mm) and middle-range (30–60 mm) connectivities were more distinctive than the long-range (>60 mm) connectivities. Interestingly, we found that functional data with a scanning length longer than 3.5 min were able to capture the individual uniqueness in the functional connectome. Our results highlight that individual uniqueness is present in the functional connectome of neonates and provide insights into the brain mechanisms underlying individual differences in cognition and behavior later in life.

Kraepelin revisited: a reassessment and statistical analysis of dementia praecox and manic-depressive insanity in 1908

1993 ◽  
Vol 23 (4) ◽  
pp. 843-858 ◽  
Author(s):  
A. Jablensky ◽  
H. Hugler ◽  
M. Von Cranach ◽  
K. Kalinov
Keyword(s):  
Meta Analysis ◽  
Original Data ◽  
Dementia Praecox ◽  
Schizoaffective Disorders ◽  
Homogeneous Groups ◽  
Manic Depressive ◽  
Original Case ◽  
State Examination ◽  
Dichotomous Classification

SynopsisA meta-analysis was carried out on 53 cases of dementia praecox (DP) and 134 cases of manic-depressive insanity (MDI) originally diagnosed by Kraepelin or his collaborators in Munich in 1908. The original case material was coded in terms of Present State Examination syndromes and analysed statistically for internal consistency and discrimination between the two diagnostic entities. Kraepelin's DP and MDI were found to define homogeneous groups of disorders which could be clearly distinguished from one another. A CATEGO re-classification of the cases revealed an 80·2% concordance rate between Kraepelin's diagnoses and ICD-9. Cluster analysis of the original data reproduced closely Kraepelin's dichotomous classification of the psychoses but suggested that DP was a narrower concept than schizophrenia today, while MDI was a composite group including both ‘typical’ manic-depressive illnesses and schizoaffective disorders.

Coaching skills for recovery a decade of providing coaching skills for recovery training at a healthcare NHS foundation trust

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Helen Kathryn Cyrus
Keyword(s):  
Work Practice ◽  
Clinical Approach ◽  
Personal Recovery ◽  
Content Type ◽  
Coaching Skills ◽  
The Difference ◽  
To Come ◽  
The Individual ◽  
The Impact ◽  
The Brain

Purpose Overview of coaching for recovery. The paper aims to show an overview of work that was carried out over 11 years with groups of mental health and physical staff. As the facilitator who had run this course for the duration in Nottingham, this was an excellent opportunity to be at the forefront of a brand new project. Design/methodology/approach The introduction of the skills are taught over two consecutive days followed by a further day a month later. The idea of coaching is to be enabled to find the answers in themselves by the use of powerful questions and using the technique of the grow model, combined with practice enables the brain to come up with its own answers. Using rapport and enabling effective communication to deliver the outcome. Findings Evidence from staff/clients and the purpose of the paper shows that when you step back it allows the individual patients/staff to allow the brain to process to create to come up with their solutions, which then helps them to buy into the process and creates ownership. Research limitations/implications The evidence suggests that the approach that was there prior to the course was very much a clinical approach to working with clients and treating the person, administering medication and not focussing on the inner person or personal recovery. The staff review has shown that in the clinical context change is happening from the inside out. Practical implications “Helps change culture”; “change of work practice”; “it changed staff focus – not so prescriptive”; “powerful questions let clients come to their own conclusions”; “coaching gives the ability to find half full. Helps to offer reassurance and to find one spark of hope”. Social implications This has shown that the approach is now person-centred/holistic. This has been the “difference that has made the difference”. When this paper looks at the issues from a different angle in this case a coaching approach, applying technique, knowledge and powerful questions the results have changed. The same clients, same staff and same problems but with the use of a different approach, there is the evidence of a different outcome, which speaks for itself. The coaching method is more facilitative, therefore it illicit’s a different response, and therefore, result. Originality/value The results/evidence starts with the individual attending and their commitment to the process over the two-day course. Then going away for the four weeks/six for managers and a commitment again to practice. Returning to share the impact if any with the group. This, in turn, helps to inspire and gain motivation from the feedback to go back to work invigorated to keep going.

Febrile Convulsions, by J. Gordon Millichap, M.D., M.R.C.P. New York: The Macmillan Company, 1968, 239 pp., $7.95

PEDIATRICS ◽  
1968 ◽  
Vol 42 (2) ◽  
pp. 381-382
Author(s):  
Randolph K. Byers
Keyword(s):  
New York ◽  
Relevant Literature ◽  
Febrile Seizures ◽  
Cerebral Injury ◽  
Extensive Review ◽  
Cerebral Disease ◽  
Febrile Convulsions ◽  
The Individual ◽  
The Brain ◽  
Made In

This rather modest-looking monograph deals not only with the large experiences of the author in relation to febrile seizures, but also presents an extensive review of the modern relevant literature (266 references in the bibliography). The most useful point made in the book, it seems to me, is that febrile convulsions are just that: i.e., convulsions coinciding with fever, the result of illness not directly involving the brain or its meninges. Such a seizure may be an isolated occurrence in the life of the individual, or it may recur a few times with fever; it may be the first sign of idiopathic chronic epilepsy, or it may be evidence of more or less apparent cerebral injury of a static sort; or, it may be the presenting symptom heralding progressive cerebral disease.

Neural Mechanisms of Negative Symptoms

1989 ◽  
Vol 155 (S7) ◽  
pp. 93-98 ◽  
Author(s):  
Nancy C. Andreasen
Keyword(s):  
Frontal Cortex ◽  
Negative Symptoms ◽  
Neural Mechanism ◽  
Brain Regions ◽  
Brain Dysfunction ◽  
Neural Mechanisms ◽  
Dementia Praecox ◽  
Intellectual Abilities ◽  
The Brain ◽  
Psychic Mechanisms

When Kraepelin originally defined and described dementia praecox, he assumed that it was due to some type of neural mechanism. He hypothesised that abnormalities could occur in a variety of brain regions, including the prefrontal, auditory, and language regions of the cortex. Many members of his department, including Alzheimer and Nissl, were actively involved in the search for the neuropathological lesions that would characterise schizophrenia. Although Kraepelin did not use the term ‘negative symptoms', he describes them comprehensively and states explicitly that he believes the symptoms of schizophrenia can be explained in terms of brain dysfunction:“If it should be confirmed that the disease attacks by preference the frontal areas of the brain, the central convolutions and central lobes, this distribution would in a certain measure agree with our present views about the site of the psychic mechanisms which are principally injured by the disease. On various grounds, it is easy to believe that the frontal cortex, which is specially well developed in man, stands in closer relation to his higher intellectual abilities, and these are the faculties which in our patients invariably suffer profound loss in contrast to memory and acquired ability.” Kraepelin (1919, p. 219)

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