An Investigation into the Fragility and Solubility of the Red Blood-cells in Mental Disease

1927 ◽  
Vol 73 (301) ◽  
pp. 257-265
Author(s):  
Margaret Scoresby-Jackson

The objects of this investigation were to find out in what respect the resistance to hæmolysis of the red blood-corpuscles differs in mental disease from the normal, and to make a contribution towards the elucidation of pathological mental states and their relationship to pathological states of organs of the body other than the brain.

2021 ◽  
Author(s):  
Andrew D. Beale ◽  
Priya Crosby ◽  
Utham K. Valekunja ◽  
Rachel S. Edgar ◽  
Johanna E. Chesham ◽  
...  

AbstractCellular circadian rhythms confer daily temporal organisation upon behaviour and physiology that is fundamental to human health and disease. Rhythms are present in red blood cells (RBCs), the most abundant cell type in the body. Being naturally anucleate, RBC circadian rhythms share key elements of post-translational, but not transcriptional, regulation with other cell types. The physiological function and developmental regulation of RBC circadian rhythms is poorly understood, however, partly due to the small number of appropriate techniques available. Here, we extend the RBC circadian toolkit with a novel biochemical assay for haemoglobin oxidation status, termed “Bloody Blotting”. Our approach relies on a redox-sensitive covalent haem-haemoglobin linkage that forms during cell lysis. Formation of this linkage exhibits daily rhythms in vitro, which are unaffected by mutations that affect the timing of circadian rhythms in nucleated cells. In vivo, haemoglobin oxidation rhythms demonstrate daily variation in the oxygen-carrying and nitrite reductase capacity of the blood, and are seen in human subjects under controlled laboratory conditions as well as in freely-behaving humans. These results extend our molecular understanding of RBC circadian rhythms and suggest they serve an important physiological role in gas transport.


2021 ◽  
Vol 2 (1) ◽  
pp. 64-69
Author(s):  
HIJRA HIDAYANA ◽  
Suswati Suswati

Hemoglobin is the red pigment-protein contained in red blood cells. The function of hemoglobin is to transport oxygen from the lungs and in the bloodstream to be carried to the tissues. Hemoglobin can increase by increasing the intake of iron in the body. One way to increase hemoglobin can be done by giving method Infused Water Dates. Infused water is a drink consisting of plain water with fresh fruit added and soaking or settling together for a certain time. The making of infused water is carried out by soaking for a period of 0 to 12 hours, so that the infused water becomes a liquid medium that carries more nutrients than ordinary water and will be more easily absorbed by cells and distributed throughout the body (Sidauruk, 2018 ). In several studies, it is stated that dates can increase hemoglobin levels in the blood. Where dates contain iron, vitamin A, vitamin C, protein to form red blood cells. With the method, Infused Water the date palm water becomes alkaline so that it can accelerate the absorption process in the body. The purpose of this study was to determine the effectiveness of dates infused water provision to increase hemoglobin levels of midwifery adolescent girls at Medan Health Polytechnic in 2020. This research was quasi-experimental study using the One Group Pretest-Posttest Without Control Design approach. The sample in this study were 20 respondents of midwifery adolescent girls from Medan Health Polytechnic, using the technique of purposive sampling. The statistical test used wa the Wilcoxon Signed Rank Test because the data was not normal. The results of the Wilcoxon Signed Rank Test obtained the value of P-Value = 0.001. So it can be concluded that the date infused water  is effective in increasing hemoglobin levels of midwifery adolescent girls at Medan Health Polytechnic in 2020.   Keywords: Dates Infused Water, Increased Hemoglobin Levels, Girls Adolescent


2020 ◽  
Vol 5 (2) ◽  
pp. 63-71
Author(s):  
Vladimir Nikulin ◽  
Aleksandra Mustafina

The aim of the study is to increase the productive qualities of broiler chickens by including ultrafine silicon oxide into main diet. During the experiment, the biological effect of ultrafine silicon oxide on broiler chickens was estab-lished. Use of ultrafine SiO2 particles for poultry feeding contributed to an increase in the number of red blood cells and content of total protein and albumins. By the end of the experiment, the number of red blood cells in birds in-creased by 17.43% (P≤0.001) – in the blood of birds of the first experimental group, 16.51% (P≤0.01) – the second one, 20.80% (P≤0.001) – the third experimental and 21.71% (P≤0.001) – the fourth experimental group, compared with the indicator of the control group. The amount of total protein in blood serum of chickens of the first and the second experimental groups increased by 1.36-1.39 %, in the third and fourth ones there was a significant (P≤0.05) increase by 5.45 and 3.05%, respectively. The blood glucose content of chickens in the experimental groups is higher by 8.04-23.65% compared to this indicator with ones in the control group. During the experiment feed con-sumption per 1 kg gain of live weight decreased: in the first experimental group by 3.00 % in the second by – 0.50 %, the third – 6.00 % the fourth– by 4.50 %, compared to this with the control group. The chicken’s vibrancy of the first the experimental group was higher by 4.77 %, the second – by 6.20 %, the third – by 19.25 % and the fourth– by 11.59% than in the control one. Consequently, when converting the feed energy into the body energy of a broiler chicken, the energy conversion coefficient of the experimental group of poultry is higher than that of the control one by 7.16-21.76 %. Thus, the most optimal dose for further research was determined.


1982 ◽  
Vol 11 ◽  
pp. 74-86 ◽  
Author(s):  
Kaj Björkqvist

The biological study of man is one of today's most rapidly advancing sciences. There is no reason for not utilizing these methodologies of research and the knowledge already gained when studying ecstasy and other similar religious phenomena. Drugs have been used in all parts of the world as an ecstasy technique. Since mental states and physiological correlates always accompany each other, it is obvious that the human mind can be affected by external means, for instance by drugs. But the opposite is also true; mental changes affect the body, as they do in the case of psychosomatic diseases. Ecstasy is often described as an extremely joyful experience; this pleasure must necessarily also have a physiological basis. It is of course too early to say anything for certain, but the discovery of pleasure centres in the brain might offer an explanation. It is not far-fetched to suggest that when a person experiences euphoric ecstasy, it might, in some way or other, be connected with a cerebral pleasure center. Can it be, for example, that religious ecstasy is attained only by some mechanism triggering off changes in the balance of the transmitter substances? Or is it reached only via a change in the hormonal balance, or only by a slowing down of the brain waves, or is a pleasure centre activated? When a person is using an ecstasy technique, he usually does so within a religious tradition. When he reaches an experience, a traditional interpretation of it already exists.


2018 ◽  
pp. 51-86
Author(s):  
Walter Glannon

This chapter examines major psychiatric disorders as disorders of consciousness, memory, and will. All of these disorders involve disturbances in how the brain processes and integrates information about the body and external world. Distorted mental content in these psychopathologies impairs the capacity to consider different action plans, and to form and execute particular plans in particular actions. Dysfunctional mental states correlating with dysfunctional neural states impair the capacity for flexible behavior and adaptability to the environment. This dysfunction also impairs the capacity for insight into a psychiatric disorder and understanding the need for and motivation to seek treatment.


Author(s):  
Nathalie Bijnens ◽  
Gregory Koutsouridis ◽  
Marcel Rutten ◽  
Frans van de Vosse ◽  
Peter Brands

Ultrasound waves, transmitted by a transducer into a body, are reflected and scattered by the materials they encounter in the body. In case of blood flow measurements in an artery, the received signal will contain the information not only from the moving red blood cells, but the reflections from the vessel wall of other soft tissue structures as well. The discrimination between ultrasound signals originating from scattering of red blood cells and reflection of tissue is one of the major problems for blood velocity assessment. Traditionally, in Doppler processing, where the highest blood velocities in the middle of the vessel are estimated, this discrimination is obtained via a high pass filter with a static cut-off frequency related to the maximum frequency content of the reflections. This is illustrated in Fig.1 (top). As illustrated in Fig. 1 (bottom), problems occur for velocity estimation of slowly moving blood cells close to the vessel wall and in case of perpendicular insonification [1]. In these cases, there is no frequency shift in the signal received from scattering on blood cells. Furthermore, the intensity of the reflections from the vessel wall is highest in case of perpendicular insonification. Filtering in these cases is very challenging since it allows the assessment of blood velocity profiles without contrast agents.


1963 ◽  
Vol 204 (6) ◽  
pp. 1071-1076 ◽  
Author(s):  
Roy L. Swank ◽  
Lavelle Jackson

Hamsters were fed large (8 g/kg) test meals of cream, cod liver oil, carbohydrate, and protein and the Ca, Na, and K levels in red blood cells, serum, urine, and tissues were determined. 1) Urinary changes consisted of a decrease in Ca and Na 4–7 hr after both cream and cod liver oil meals. These changes were most marked after cream. Potassium excretion also decreased after cod liver oil meals, but increased after cream meals. 2) Seven hours after lipid meals both Ca and K were decreased in red blood cells. At the same time Ca and Na decreased in serum after cod liver oil meals, and the K initially increased after both lipid meals. 3) Cation changes in the heart 7 hr after feeding consisted of a reduction in Ca and Na, and a possible increase in K after cream. These changes did not occur after test meals of water, protein, carbohydrate, or cod liver oil. 4) In the brain, Ca, Na, and K were all decreased 7 hr after cream meals, and increased by all other meals. 5) Significant dehydration of all tissues was present 7 hr after cream meals. This was not observed after any other test meals.


2017 ◽  
Vol 4 (3) ◽  
pp. 192-197
Author(s):  
Ram Gopal ◽  
Tara Chand

Anemia is a condition in which the number of red blood cells or the amount of hemoglobin is low. Red blood cells contain hemoglobin protein that it enables them to carry oxygen from the lungs and deliver it to all parts of the body. A study conducted to assess the effectiveness of structured teaching programme on knowledge regarding prevention of anemia among adolescent girls in a selected senior secondary schools of Bharatpur. During the study, 60 adolescence girls were selected for them pretest is administered for assessing knowledge. After evaluation pretest score was showing lower knowledge regarding prevention of anemia then structured teaching program on knowledge of prevention from anemia administered after one week post test conducted by using same questionnaire this time girls shows increased knowledge regarding prevention of anemia and they are following healthy food habits for the prevention of anemia. Results showing adequate knowledge various methods are used for measuring the variables such as mean, mode, and standard deviation for significance of demographic variables chi square test were used there is no significant demographic variables.Int. J. Soc. Sc. Manage. Vol. 4, Issue-3: 192-197


2016 ◽  
Vol 79 (6) ◽  
pp. 922-928 ◽  
Author(s):  
Tara G Zamora ◽  
Sixto F Guiang ◽  
John A Widness ◽  
Michael K Georgieff

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