scholarly journals The impact of olanzapine on attitude to medication and quality of life in schizophrenia

2001 ◽  
Vol 25 (10) ◽  
pp. 378-381 ◽  
Author(s):  
James Stallard ◽  
Eileen Joyce

AIMS and MethodThis study aimed to compare the subjective quality of life and attitudes to medication between groups of patients with schizophrenia taking either olanzapine or traditional antipsychotic medication.ResultsThe two groups were matched for age, gender, length of illness and antipsychotic group demonstrated more extrapyramidal side-effects (EPS) and akathisia. Within this group, those with EPS scored lower on the affect balance scale of the Lancashire Quality of Life Scale than those without. More patients in the olanzapine group reported that medication was taken to prevent symptoms returning.Clinical ImplicationsThese results lend support to the hypothesis that the presence of EPS impairs quality of life and suggest that olanzapine therapy may improve patients' attitudes to medication.

2018 ◽  
Vol 31 (3) ◽  
pp. e100037 ◽  
Author(s):  
Yi Guo ◽  
Shumin Qu ◽  
Hongyun Qin

BackgroundStudies conducted outside of China have found that stigma can predict low quality of life, and research in China has shown that stigma has an impact on the quality of life of convalescent patients with schizophrenia. Nevertheless, there is no indepth research on the impact of stigma on the quality of life of patients.AimsTo research the correlation of stigma and the subjective quality of life of persons with chronic schizophrenia in the community.MethodsWe adopted a stratified sampling method. General questionnaire, quality of life scale and stigma scale were given to 602 persons with chronic schizophrenia in the community.ResultsThe mean (SD) value of the Subjective Quality of Life Scale total scores was 32.99 (13.85). The mean (SD) value of the total stigma scores was 43.50 (5.02). After correlation analysis and multivariate stepwise regression analysis, it was shown that the total scores for self-stigma and each factor were positively correlated with subjective quality of life (r=0.462,p<0.001), psychosocial factors (r=0.517,p<0.001), and symptoms and adverse reaction factor scores (r=0.363,p<0.001), and the correlation coefficients were statistically significant.ConclusionsThe higher the stigma of persons with schizophrenia in the community, the lower the subjective quality of life is. This suggests that reduction of self-stigma should be considered in the improvement of the quality of life of persons with schizophrenia in the community.


Author(s):  
Germina-Alina Cosma ◽  
Alina Chiracu ◽  
Amalia Raluca Stepan ◽  
Marian Alexandru Cosma ◽  
Marian Costin Nanu ◽  
...  

The aim of this study was to analyze athletes’ quality of life during the COVID-19 pandemic. The study involved 249 athletes between 15 and 35 of age, M = 21.22, SD = 5.12. The sample was composed of eight Olympic Games medalists, three European medalists, 67 international medalists, and 63 national medalists. The instruments used were: (1) COVID-19 Anxiety Scale, (2) Athlete Quality of Life Scale, (3) Impact of Pandemic on Athletes Questionnaire, and (4) International Personality Item Pool (IPIP Anxiety, Depression, and Vulnerability Scales). The results indicate significant differences in COVID-19 anxiety depending on the sport practiced, F (9239) = 3.81, p < 0.01, showing that there were significant differences between sports. The negative impact of the COVID-19 pandemic mediates the relationship between trait anxiety and the athletes’ quality of life. The percentage of mediation was 33.9%, and the indirect effect was −0.11, CI 95% (−0.18, −0.03), Z = −2.82, p < 0.01. Trait anxiety has an increasing effect on the intensity of the negative impact of the COVID-19 pandemic, 0.23, CI 95% (.10, 0.35), Z = 3.56, p < 0.01, and the negative impact of the COVID-19 pandemic has a decreasing effect on quality of life, −0.47, CI 95% (−0.67, −0.27), Z = −4.62, p < 0.01. Gender and age did not moderate the relationship between the negative impact of COVID-19 and athletes’ quality of life. The results of the study highlighted the impact that social isolation and quarantine have on athletes’ affective well-being.


2015 ◽  
Vol 46 (3) ◽  
pp. 680-687 ◽  
Author(s):  
Brian D. Stucky ◽  
Cathy D. Sherbourne ◽  
Maria Orlando Edelen ◽  
Nicole K. Eberhart

This study identifies the unique contributions of asthma severity, symptoms, control and generic measures of quality of life (QoL) to asthma-specific QoL, as measured by the 12-item RAND Negative Impact of Asthma on Quality of Life scale (RAND-IAQL-12).Using a sample of 2032 adults with asthma, we conducted multiple regression analyses that sequentially examined hypothesised predictors of asthma-specific QoL. The change in variance accounted for and total unique variance accounted for is calculated as hypothesised predictors are added in each step.Our results indicate that asthma severity and asthma symptoms are strong predictors of asthma-specific QoL only when not controlling for aspects of asthma control. In regression models that include other aspects of asthma control, the contributions of both asthma symptoms and severity were substantially reduced, with asthma control and aspects of QoL related to social roles and activities emerging as the strongest predictors of asthma-specific QoL.These findings suggest that researchers measuring the impact of asthma on QoL should also consider the importance of asthma control as measured by the RAND Asthma Control Measure (RAND-ACM) and generic QoL scales that measure aspects of daily life that are uniquely affected by asthma.


2019 ◽  
Vol 9 (3) ◽  
pp. 55
Author(s):  
Jaroslav Michalek ◽  
Alena Vrablikova ◽  
Karl Heinrich ◽  
Zuzana Dudasova

A 48-year-old male, who suffered from a stroke resulting in cerebellum damage and occlusion of the left vertebral artery, underwent stromal vascular fraction therapy. The clinical status of the patient was monitored by a modified Stroke Specific Quality of Life Scale before therapy and at 3, 9, 12, 18, 24, and 32 months after therapy. Three months after therapy, the patient felt a reduction in pain, vertigo, and fatigue. After 9 months, he was able to walk safely on his own. After 24 months, he was able to ride a bicycle. After 32 months, he felt completely healthy without any limitations or handicaps. Therefore, intravenous application of stromal vascular fraction cells represents a promising strategy for the treatment of patients after a stroke.


2015 ◽  
Vol 29 (2) ◽  
pp. 165-182
Author(s):  
Shawn M. Fitzgerald ◽  
Jian Li ◽  
Phillip D. Rumrill ◽  
Malachy Bishop ◽  
William R. Merchant

Rehabilitation counseling researchers seeking to more fully understand the phenomenon of psychosocial adaptation to disability are devoting increased attention to the impact of disability on quality of life (QOL). This impact has been of particular interest among multiple sclerosis (MS) researchers. The complex etiology, unpredictable nature, and the multiple functional limitations attendant to MS have been identified as major impediments in research efforts to develop psychometrically sound and clinically sensitive tools to evaluate the impact of MS on QOL. This article presents the results of a confirmatory factor analysis of the factor structure of the Quality of Life Scale (QOLS), which has been used in several studies to evaluate the impact of MS on QOL. The QOLS was developed to assess the self-reported QOL of people with chronic pain and evaluates the degree of satisfaction with 7 distinct domains of personal and social activity. The developers’ original principal component analysis revealed a single-factor model with high levels of internal consistency reliability. It is not clear, however, how the 1-factor model fits the population of individuals with MS and how the 7 items perform in terms of their measurement of the single factor. The 1-factor structure of the QOLS did not fit the data well in this sample of individuals with MS. Subsequent model iterations that incorporated 3 error covariances provided increasingly better fit and resulted in a reasonable model fit to the data.


2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Marta Makara-Studzińska ◽  
Małgorzata Wołyniak ◽  
Karolina Kryś

Schizophrenia is the most severe and most debilitating mental illness, which is one of the first ten causes of disability in youth and elderly people. Regarding many consequences that schizophrenia brings for individual and social functioning of ill people, their assessment of the quality of their lives seems to be interesting. The aim of this study is to evaluate the incidence and severity of anxiety and depression as well as analysis of the impact level of anxiety and depression on life quality of people with schizophrenia. A group of patients with schizophrenia from psychiatric centers was involved in a study. A set of methods, included: author's questionnaire, the quality of life scale WHOQOL-BREF, and the hospital anxiety and depression scale (HADS). Anxiety disorders occurred in more than 78% of respondents, while depressive disorders in more than half of respondents. The more severe anxiety and depressive disorders, the lower values were observed in all tested components of quality of life. The study of quality of life of the mentally ill patients should be conducted on a continuous basis in order to explore the current factors influencing the improvement of their psychophysical welfare. It is necessary to promote prohealthy mental lifestyle.


2017 ◽  
Vol 22 (3) ◽  
pp. 263-266 ◽  
Author(s):  
Chelsea McLellan ◽  
Marc Philip Frey ◽  
Jerry Tan

Purpose: While acne, a common condition, largely involves the face, chest, and back, current acne quality-of-life measures focus primarily on facial acne. The purpose of this study was to assess the need for a comprehensive quality-of-life measure intended for use with patients who have facial and/or torso acne. Methods: We evaluated the need for a comprehensive quality-of-life scale for facial and torso acne based on data from an epidemiological survey (N = 690) in which participants were grouped according to the location of their acne (face, torso, or both) and where quality of life was assessed. Results: Analysis of variance results revealed that participants with acne on their torso reported the highest levels of quality of life while participants with acne on their face reported the lowest levels. Conclusions: There is a need for a quality-of-life instrument that assesses the impact of acne on the face and torso separately. This unmet need can be addressed with a comprehensive acne quality-of-life measure that is inclusive of torso acne.


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