scholarly journals MON-619 Predictors of Complications with Fasting the Holy Month of Ramadan in Patients with Diabetes

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Ali Ahmed Al Qarni ◽  
Reem Mohammad Alamoudi ◽  
Salwa Al-Aidarous ◽  
Awad Saad Alshahrani ◽  
Munir Abuhelalah ◽  
...  

Abstract Background: For a whole month, every year Muslims fast daily from dawn to sunset. Those with health conditions that put them at risk are exempted from fasting, yet most of patients with diabetes choose to fast. Clinical and metabolic complications of diabetes during this month are issues of concern for patients and their managing physicians. This study is designed to evaluate the impact of fasting Ramadan on safety of patients. Methods: A multicentercross-sectional survey was conducted in four hospitals under the Ministry of National Guard Health Affairs; King Abdulaziz Hospital,Al-Ahsa, Imam Abdulrahman bin Faisal Hospital, Dammam, King Abdulaziz Medicalcities, Riyadh and Jeddah. All patients with diabetes followed in the diabetes clinics of all four centers who fulfilled the study inclusion and exclusion criteria were approached within three months post Ramadan and consented for participation in the survey, then filled a self-administered validated questionnaire that consisted of 15 items. Results: Socio-demographic,clinical, and laboratory characteristics of 1438 patients with diabetes were analyzed. The majority 1207 (83.9%) had type II diabetes, and 828 (57.6%) were females.The mean age was 57.9 ± 14.9 years, and mean BMI 25.25 ± 5.39.The majority 1060 (73.7%) had concomitant diseases. 36 (2.5%)were on diet therapy alone, 147 (10.2%) on metformin monotherapy, and 261 (18.2%) on insulin therapy alone. The remaining 994 (69.1%) were on combination of insulin and oral agents. Health education was received on average by 688 (57.8%) of patients. Out of the 1191 (82.8%) who fasted the full month, 497 (41.7%) experienced acute glycemic complications. Multivariate analyses revealed that significant predictors for unsafe fasting were: type I diabetes [OR 1.8 (95%CI 1.2 - 2.8), p-value 0.007], insulin therapy [OR 1.8 (95% CI 1.4 - 2.3), p-value0.0001], previous history of breaking fast for glycemic reasons [OR 2.1 (95% CI1.5 - 2.9), p-value 0.0001], and not receiving health education [OR 1.6 (95% CI1.2 - 2.0), p-value 0.0006]. Blood sugar control, presence of concomitant diseases, and history of diabetes related hospitalization were not statistically significant predictors [(OR 1.25, 95% CI, 0.9 - 1.7, p-value 0.15),(1.3, 95% CI, 0.9 - 1.8, p-value 0.14), (1.1, 95% CI, 0.8 - 1.6, p-value 0.45)] respectively. Conclusion: A significant proportion of patients with diabetes do not receive specific education pertinent to fasting Ramadan. Lack of health education, in addition to; type I diabetes, insulin therapy, and previous experience of complications are predictors for unsafe fasting. This highlights the need for better structured educational programs and further research in the field.

2012 ◽  
Vol 18 (1) ◽  
pp. 13-18
Author(s):  
Irina Franciuc ◽  
Cristina Maria Mihai ◽  
Alina Martinescu ◽  
Loredana Mariana Aftenie ◽  
Adina Honcea

AbstractThe aim of this study was to present the cases with family history of type 1 diabetes in a group of pediatric patients from the Clinic of Pediatrics, Constanta County Hospital, and to analyze the risk for relatives conferred by presence of particular DR genotypes. 8 out of 60 index cases had relatives affected with type 1 diabetes (13.33%). Of these, four had firstdegree relatives affected (6.67%) and were presented here. Although high-risk genotypes were more frequent in the group of familial cases, no association was found between DR genotype and family history of type 1 diabetes when statistical significance was tested (p value 0.119).


Author(s):  
P. Amulya Reddy ◽  
K. Saravanan ◽  
A. Madhukar

Aim: The aim of the study was to evaluate the QOL of patients with Diabetes Mellitus. Study Design: This was a prospective, observational study. Duration of Study: The study was conducted from August 2019 to January 2021 in Yashoda Hospital, Hyderabad. Methodology: Patients of either sex with ≥1year history of diabetes willing to give the consent were included in the study. Patients of either sex with <1year history of DM, Pregnant/lactating women and patients not willing to give the consent were excluded from the study. Data on Blood glucose levels (FBS, PPBS) and HbA1C was also obtained and assessed. QOLID questionnaire was administered to the patients and assessed which consisted of a set of 34 items representing 8 domains such as Role limitation due to the physical health, Physical endurance, General health, Treatment satisfaction, Symptom botherness, Financial worries, Mental health, and Diet satisfaction). Results: A total of 200 patients were analysed in the study,108(54%) were males and 92(46%) were females. The average age of the patients was 58.5 years with majority being 51-70years (73.5%) of age. Patients with higher age and females had poor QOL compared to others. The correlation between various categorical variables with that of scores of QOL in various domains was assessed, Age of the patients influenced QOL score in various domains like RLPH (p value-0.038), PE (p value-0.0183), and SB (p value-0.0002), Gender has influenced QOL score in domains like RLPH (p value-0.0008), PE (p value-0.0106), TS (p value-0.0005) and Educational Qualification has influenced QOL score in RLPH (p value-0.0008), GH (p value-<0.0001), TS (p value-<0.0001), E/MH (p value-<0.0001). Conclusion: The results concluded that overall QOL was noticeably low in Diabetic patients especially in Women and elderly thus indicating that Diabetes management is not restricted to treatment but also requires attention on QOL of patients.


2021 ◽  
Vol 2 (1) ◽  
pp. 17-22
Author(s):  
Ikada Septi Arimurti ◽  
Rita Dwi Pratiwi ◽  
Wannasta Alayya

Abstrak: Data Riskesdas tahun 2018 menyatakan bahwa pada bayi umur 0-5 bulan di Indonesia, proporsi pola pemberian ASI sebanyak 37,3% ASI ekslusif, sedangkan pada ASI parsial dan ASI predominan masing-masing sebesar 9,3%, dan 3,3%. Hal ini menunjukkan bahwa angka ASI eksklusif kita masih tergolong rendah. Perawatan payudara adalah faktor yang berpengaruh terhadap keberhasilan proses menyusui pada ibu nifas, selain faktor lainnya. Penelitian sebelumnya mengungkapkan terdapat hubungan yang signifikan antara perawatan payudara dengan keberhasilan proses menyusui dengan p-value sebesar 0,007. Tujuan pengabdian masyarakat ini adalah memberi edukasi kepada masyarakat khususnya ibu nifas untuk dapat melakukan perawatan payudara pada masa nifasnya sehingga bisa mendukung program ASI eksklusif. Metode pengabdian masyarakat dilakukan melalui ceramah dan simulasi perawatan payudara. Pendidikan kesehatan dilakukan oleh dosen dan mahasiswa STIKes Widya Dharma Husada Tangerang. Kegiatan bertempat di Posyandu Dewi Sri Pamulang Kota tangerang Selatan. Pelaksanaannya pada saat kegiatan posyandu lalu disertakan pendidikan kesehatan dengan tema perawatan payudara pada ibu nifas. Peserta kegiatan sebanyak 15 orang ibu nifas. Terdapat antusiasme warga saat kegiatan berlangsung. Dampak kegiatan ini peserta mengetahui cara melakukan perawatan pada payudara sehingga sangat bermanfaat dalam proses menyusuinya. Harapan selanjutnya adalah kader posyandu juga dapat terus memberikan pendidikan kesehatan mengenai perawatan payudara pada ibu nifas yang belum memahami bagaimana merawat payudara selama proses menyusui.Abstract: Riskesdas data for 2018 states that in infants aged 0-5 months in Indonesia, the proportion of breastfeeding patterns is 37,3% exclusive breastfeeding, while partial breastfeeding and predominant breastfeedings are 9,3% and 3,3%, respectively. This shows that our exclusive breastfeeding rate is still low. Breast care is one of the factors that influence the success of the breastfeeding process in postpartum mothers and other factors. Previous research revealed a significant relationship between breast care and the success of the breastfeeding process with a p-value = 0,007. This community service aims to provide education to the community, especially postpartum mothers, to carry out breast care during the puerperium so that they can support the exclusive breastfeeding programs. Community service methods are carried out through lectures and simulations of breast care. Health education is carried out by lecturers and students of STIKes Widya Dharma Husada Tangerang. The activity took place at Posyandu Dewi Sri Pamulang, South Tangerang City. It was implemented during the posyandu activities and then included health education with breast care for postpartum mothers. Participants in the activity were about 15 mothers. There was enthusiasm from the residents when the activity took place. The impact of this activity, participants know how to do a treatment on the breast, so it is very beneficial in breastfeeding. The next hope is that posyandu cadres can also continue to provide health education on breast care to mothers who do not understand how to care for the breast during the breastfeeding process.


2018 ◽  
Vol 11 (3) ◽  
pp. 25-29
Author(s):  
A.N. Samoylov ◽  
◽  
T.R. Khaibrakhmanov ◽  
G.A. Fazleeva ◽  
P.A. Samoylova ◽  
...  

1991 ◽  
Vol 12 (5) ◽  
pp. 373-376 ◽  
Author(s):  
H. Peter Chase ◽  
Satish K. Garg ◽  
Sandy L Hoops ◽  
Sherrie Harris ◽  
William Wilcox

2018 ◽  
Vol 3 (1) ◽  
Author(s):  
Masta Hutasoit

Background: Bantul is one of the areas in Yogyakarta that is at risk of disaster. The results of interviews with the head of SD N 2 Padokan found that the school had never had any training on disaster and not yet implemented the curriculum on disaster mitigation. Children are age groups that are very vulnerable to the impact of both physical and psychological disasters. Knowledge of disaster preparedness is important for disaster preventionThe purpose of the study: to determine the effect of health education on knowledge of student preparedness to earthquake disaster events in SD N 2 Padokan, Bantul.Method: This research is quantitative research with quasi experiment design. The design used was pre test and post test nonequivalent control group. The number of samples in the intervention group and the control group were 27 students of class V. The sampling were collected by purposive sampling according to the criteria. Methods of data collection using questionnaires and using nonparametric statistical analysis Wilcoxon with the help of SPSS v.17 for Windows program.Results: The results showed no effect of health education on earthquake disaster preparedness knowledge in SD N 2 Padokan obtained p value 0.480 with α 0.05. In the intervention group the difference of knowledge before and after is indicated by p value 0.180, while for the control group 1,000.Conclusion: there is no effect of health education on disaster preparedness knowledge in SD N 2 Padokan.  


1999 ◽  
Vol 1 (4) ◽  
pp. 313-323 ◽  
Author(s):  
Boris P. Kovatchev ◽  
Leon S. Farhy ◽  
Daniel J. Cox ◽  
Martin Straume ◽  
Vladimir I. Yankov ◽  
...  

A dynamical network model of insulin-glucose interactions in subjects with Type I Diabetes was developed and applied to data sets for 40 subjects. Each data set contained the amount of dextrose + insulin infused and blood glucose (BG) determinations, sampled every 5 minutes during a one-hour standardized euglycemic hyperinsulinemic clamp and a subsequent one-hour BG reduction to moderate hypoglycemic levels. The model approximated the temporal pattern of BG and on that basis predicted the counterregulatory response of each subject. The nonlinear fits explained more than 95% of the variance of subjects' BG fluctuations, with a median coefficient of determination 97.7%. For all subjects the model-predicted counterregulatory responses correlated with measured plasma epinephrine concentrations. The observed nadirs of BG during the tests correlated negatively with the model-predicted insulin utilization coefficient (r = -0.51,p< 0.001) and counterregulation rates (r= -0.63,p< 0.001). Subjects with a history of multiple severe hypoglycemic episodes demonstrated slower onset of counterregulation compared to subjects with no such history (p< 0.03).


2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Ebru Atalar ◽  
Cuneyd Gunay ◽  
Hakan Atalar ◽  
Tugba Tunc

A 49-year-old male presented with acute midthoracic severe back pain following a witnessed nocturnal convulsion attack. There was no history of trauma and the patient had a 23-year history of Type I diabetes mellitus. MRI scans of the thoracic spine revealed compression fractures at T5, T6, T7, and T8 vertebrae. The patient was treated conservatively. At 17 months after the initial diagnosis, the complaints of back pain had been resolved and the patient was able to easily undertake daily living activities. Hypoglycaemia is a common problem in diabetic patients treated with insulin. Convulsions may occur as a consequence of insulin-induced hypoglycemia. Nontraumatic compression fractures of the thoracic spine following seizures are a rare injury. Contractions of strong paraspinal muscles can lead to compression fracture of the midthoracic spine. Unrecognized hypoglycaemia should be considered to be a possible cause of convulsions in insulin-dependent diabetic patients. The aim of this report is to point out a case of rarely seen multilevel consecutive vertebrae fractures in a diabetic patient after a nocturnal hypoglycaemic convulsion attack.


1999 ◽  
Vol 97 (2) ◽  
pp. 149-156 ◽  
Author(s):  
Flemming WOLLESEN ◽  
Lars BERGLUND ◽  
Christian BERNE

Insulin stimulates endothelin-1 (ET-1) expression in a dose-response relationship, and ET-1 effects on vascular wall structure are similar to the long-term complications of diabetes. We therefore determined whether the plasma ET-1 concentration in patients with diabetes is associated with their total insulin exposure to see if plasma ET-1 might be a link between insulin exposure and long-term complications of diabetes. We studied 69 patients with Type I and 40 patients with Type II diabetes mellitus in equally tight glycaemic control for 2 years in a cross-sectional design. We measured basal and glucagon-stimulated plasma C-peptide, abdominal sagittal diameter, skinfold thickness, glomerular filtration rate, albumin excretion rate and standard clinical characteristics. Mean HbA1c was 6.4% in Type I and 6.3% in Type II diabetes. Patients with an albumin excretion rate > 300 μg/min were excluded. Adjusted mean plasma ET-1 was 4.11 (S.E.M. 0.39) pg/ml in 21 normal subjects, 3.47 (0.19) pg/ml in Type I diabetes and 4.84 (0.26) pg/ml in Type II diabetes (P = 0.0001). In all patients with measurable plasma C-peptide, plasma ET-1 was associated with basal plasma C-peptide (r = 0.5018, P < 0.0001), with stimulated plasma C-peptide (r = 0.5379, P < 0.0001), and with total daily insulin dose (r = 0.2219, P = 0.00851). Abdominal obesity, metabolic abnormalities, blood pressure and glomerular filtration rate were not associated with plasma ET-1, when corrected for C-peptide and daily insulin dose. Our study shows that the plasma concentration of ET-1 is closely associated with insulin secretion and insulin dose in patients with diabetes. Plasma ET-1 is higher in Type II diabetes than in Type I diabetes. Increased insulin exposure in patients with diabetes may have long-term effects on vascular wall structure through its stimulation of ET-1 expression.


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