scholarly journals Obesity, Dyslipidemia, Diabetes, and Vitamin D Levels

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A278-A278
Author(s):  
Elena A Amoroso Moya ◽  
Marcelo Nicolalde ◽  
Herbarth Torres
Keyword(s):  
Vitamin D ◽  
Cluster Analysis ◽  
Cross Sectional Study ◽  
Atherogenic Dyslipidemia ◽  
Cross Sectional ◽  
Analysis Group ◽  
Sequential Sample ◽  
Vitamin D Levels ◽  
Different Levels

Abstract Context: There are several studies that refer to an association between vitamin D levels and the prevalence of atherogenic dyslipidemia and diabetes 2, however these studies present different non-conclusive results. Methods: A cross-sectional study was carried out with a propositional sequential sample of 110 patients at Rio and San Juan Hospital Riobamba -Ecuador 2020. The sample was divided into three groups according to BMI and vitamin D levels; 25 hydroxycalciferol, by cluster analysis, the final groups G1(56), G2(59), and G3(16) had a similar BMI average of 27 kg/m2, and significant differences in the average of vitamin D: G1 = 13.6, G2 = 24.5 and G3 = 45.3 ng/dl. Results: The prevalence of dyslipidemia increased gradually as the average level of vitamin D of the group increased as follows: G1 = 12.5%, G2 = 18.6%, G3 = 18.8%, the same behavior was observed in the prevalence of type 2 diabetes per analysis group: G1 = 30.4%, G2 = 45.8% and G3 = 50%. The differences found in the prevalence of atherogenic dyslipidemia and diabetes 2 were not statistically significant p> 0.05. Conclusion: in the group of patients studied and divided by cluster analysis into three groups with different levels of vitamin D, there were no statistically significant differences with respect to the prevalence of atherogenic dyslipidemia and diabetes 2.

scholarly journals Study of vitamin d levels in patients with type 2 diabetes mellitus

2021 ◽  
Vol 9 (1) ◽  
pp. 13-20
Author(s):  
Dr. J.V. Srujan ◽  
◽  
Dr. Surya Prakash Rao ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Vitamin D Levels ◽  
Study Results

Introduction: Diabetes is defined as a disturbance in intermediary metabolism manifesting aschronic sustained hyperglycemia, primarily due to either an absolute or a relative lack of insulin.Many epidemiological studies have demonstrated an inverse relationship between vitamin D levelsand diabetes mellitus. However, there is a paucity of literature regarding the levels of vitamin D intype 2 diabetes, which is common in our community. This study was taken up to shed more light onthis issue. Material and methods: This was a cross-sectional study conducted at NRI Institute ofMedical Sciences, Sangivalasa, Visakhapatnam district. Cases of Type 2 Diabetes Mellitus attendingto the outpatient department, diagnosed as per the ADA criteria of 2011, between the ages of 31and 75 years constituted the material for the present study. Results and conclusion: Vitamin Dlevels were found to be significantly lower in the study group (19.91±7.0 ng/ml) as compared to thecontrol group (32.22±4.0 ng/ml).

scholarly journals DIFFERENCES OF VITAMIN D LEVELS IN CONTROLLED AND UNCONTROLLED TYPE 2 DIABETES MELLITUS ( DM ) PATIENTS

2019 ◽  
Vol 26 (1) ◽  
pp. 18
Author(s):  
Adhisti Adhisti Azlin ◽  
Ratna Akbari Ganie ◽  
Santi Syafril
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Vitamin D Levels ◽  
Dm Type 2

Vitamin D as an immunomodulator, plays an important role in controlling glycemic levels and decreasing diabetes complications. HbA1c is a marker of glycemic control which is known to have association with vitamin D. This study aims to see the differences in vitamin D serum levels and glycemic index in patients with type 2 DM.The design of this study is cross-sectional study and it was performed in RSUP HAM in December 2017 until March 2018. DM type 2 patients were classified based on HbA1c <7% controlled and ≥ 7% uncontrolled. Vitamin D serum levels were examined using the Enzyme-Linked Fluourescent Assay (ELFA) method., differences in vitamin D levels among controlled and uncontrolled type 2 diabetes mellitus were assessed by using independent t-test, and the differences of HbA1c level were assessed using Mann-Whitney-U test.45 patients with type 2 DM were divided into controlled (HbA1c <7%) and uncontrolled patients (HbA1c ≥ 7%). There was no difference in vitamin D serum levels between controlled and uncontrolled DM Type 2 patients (p = 0,310).

scholarly journals High prevalence of peripheral neuropathy in multiple myeloma patients and the impact of vitamin D levels, a cross-sectional study

2021 ◽  
Author(s):  
B. E. Oortgiesen ◽  
J. A. Kroes ◽  
P. Scholtens ◽  
J. Hoogland ◽  
P. Dannenberg - de Keijzer ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Vitamin D ◽  
Peripheral Neuropathy ◽  
Hypovitaminosis D ◽  
Cross Sectional Study ◽  
Clinical Trial Registration ◽  
Cross Sectional ◽  
Validated Questionnaire ◽  
Vitamin D Levels ◽  
The Impact

Abstract Purpose Peripheral neuropathy (PN) is common in patients with multiple myeloma (MM). We hypothesized that the relationship between hypovitaminosis D and PN described in diabetes mellitus patients may also be present in MM patients. Methods To study this potential association, we assessed the incidence of hypovitaminosis D (vitamin D < 75 nmol/L [= 30 ng/mL]) in smouldering and active MM patients in two Dutch hospitals. Furthermore, a validated questionnaire was used to distinguish different PN grades. Results Of the 120 patients included between January 2017 and August 2018, 84% had an inadequate vitamin D level (median vitamin D level 49.5 nmol/L [IQR 34–65 nmol/L]; mean age: 68 years [SD ± 7.7]; males: 58%). PN was reported by 69% of patients (n = 83); however, of these 83 patients, PN was not documented in the medical records of 52%. An association was found between lower vitamin D levels and higher incidence of PN in the total population (P = 0.035), and in the active MM patients (P = 0.016). Conclusion This multi-centre cohort study showed that PN and hypovitaminosis D are common in MM patients, and addressing low vitamin D levels in the treatment of MM patients might be beneficial in reducing the risk of PN. More attention for PN is warranted, as PN is underreported by clinicians. Further research is needed to fully understand the implications of vitamin D in the development of PN in patients with MM. Clinical trial registration Netherland Trial Register NL5835, date of registration July 28, 2016

The Biochemical Parameters and Vitamin D Levels in ICU Patients with Covid-19: A Cross-Sectional Study

2021 ◽  
Vol 21 ◽  
Author(s):  
Hamed Abdollahi ◽  
Farahnaz Salehinia ◽  
Mostafa Badeli ◽  
Elmira Karimi ◽  
Hossein Gandomkar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Immune System ◽  
Liver Enzymes ◽  
Serum Vitamin ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Elevated Liver Enzymes ◽  
Vitamin D Levels

Background: In Covid-19 infection, leukopenia, inflammation, and elevated liver enzymes are found in most patients. Also, vitamin D deficiency attenuate the immune system and predispose a person more susceptible to infection. In this context, we aimed to evaluate vitamin D, Electrolytes, Complete blood count, Liver enzymes, Urea, Creatinine, Albumin, CRP and ESR levels in patients with Covid-19. Methods: We conducted a cross-sectional study on 118 patients with Covid-19 who were hospitalized from 2020/2/19 to 2020/4/3 in ICU. Serum levels of electrolytes, liver enzymes, blood factors, urea, creatinine, CRP and ESR as well as anthropometric parameters and serum vitamin D concentration were measured. Results: A total of 118 patients (80 male and 38 female) was enrolled in the study (65.05±15.75 years). Only 5.08% of patients had no risk factors and 55.9% had ≥ 2 risk factors. Diabetes (44.1%) and obesity (23.7%) were more common among patients. Laboratory finding showed that 80.50% of patients had hyponatremia, but other electrolytes included K, Mg, Ca and P were normal in majority of participants as well as CBC, Cr, Urea, Alb, ALT and ALKP. The AST concentration increased in most patients (66.94%). All patients had high levels of inflammatory factors such as CRP and ESR. The mean of 25-hydroxy-vitamin D levels in participants (25.95 ± 14.56 ng/mL) was lower than its levels in general papulation. However, it was not statistically significant (P= 0.88). A significant negative correlation found between vitamin D and ALT (P= 0.02, -0.21) as well as vitamin D and CRP (P= 0.05, -0.17). Conclusion: Regarding to the regulatory role of vitamin D in immune system and low levels of vitamin D in Covid-19 infected patients, the evaluation of vitamin D levels and prescribe supplements if necessary is suggested.

scholarly journals Cross-sectional study reveals a high prevalence of vitamin D deficiency among healthy school children in central Kerala, India

2019 ◽  
Vol 6 (2) ◽  
pp. 867
Author(s):  
Ayyappan Anitha ◽  
Suresh A. Poovathinal ◽  
Vijitha Viswambharan ◽  
Ismail Thanseem ◽  
Mahesh M. Vasu ◽  
...  
Keyword(s):  
Vitamin D ◽  
School Children ◽  
Skin Color ◽  
Economic Status ◽  
Cross Sectional Study ◽  
Vitamin D Status ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitamin D Levels ◽  
High Prevalence

Background: Authors examined serum vitamin D status among the healthy school children belonging to the south Indian state of Kerala.Methods: A cross-sectional study, participants were recruited through medical camps organized in Thrissur and Palakkad districts of central Kerala during the months of March and April 2017. A 174 healthy school children (98 males and 76 females) aged 5-13 years were recruited for the study. The children were found to be healthy on the basis of physical examination by a Paediatrician. None of the children had any symptoms of skeletal deformities. All the children were drug-naive. Data on height, weight, skin color, food habits, physical activities and socio-economic status were recorded. A 2ml of peripheral blood samples were collected from the participants. Total vitamin D in the serum was estimated by chemiluminescence immunoassay (CLIA).Results: VDD was observed in 60.92% and insufficiency in 30.46% of the participants. Only 8.62% of the participants had normal vitamin D levels. The mean vitamin D level was 19.93 ng/ml. Males had significantly higher vitamin D levels compared to females. Factors such as age, height, weight, diet, skin color and socio-economic status did not influence vitamin D levels.Conclusions: This is the first study of vitamin D status among the school-age children of Kerala. This paper adds further evidence to the reports indicating high prevalence of subclinical VDD among children across India and calls for action.

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