An Org-1-Tup transcriptional cascade reveals different types of alary muscles connecting internal organs in Drosophila

Fetus acardius amorphus is a rare congenital malformation characterized by the lack of a functional heart, the presence of a bivascular umbilical cord, as well as a developed and organized skeletal system and partially organized inner organs. Fetus acardii mostly occur in multiple gestations. The pathogenesis of this entity is not clarified yet. It has been hypothesized that, although formation of anastomosing vessels between the co-twin and the anomalous embryo as well as reverse directed blood flow within the umbilical arteries of the weaker twin may allow sufficient blood flow to form rudimentary internal organs, it is insufficient to develop a fully functional heart. We had a case of fetus acardius amorphus, where we performed autopsy as well as routine histology assessment to identify different types of tissues. We showed that our fetus acardius amorphus demonstrated histomorphological features of renal tubular dysgenesis, confirmed by lack of proximal tubules, extramedullary hematopoiesis and increased number of smooth muscle actin positive vessels. This is a novel finding and has not been reported previously.

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Alary muscles and thoracic alary-related muscles are atypical striated muscles involved in maintaining the position of internal organs

Development ◽

10.1242/dev.185645 ◽

2020 ◽

Vol 147 (8) ◽

pp. dev185645

Author(s):

Laetitia Bataillé ◽

Nathalie Colombié ◽

Aurore Pelletier ◽

Achim Paululat ◽

Gaëlle Lebreton ◽

...

Keyword(s):

Striated Muscles ◽

Internal Organs ◽

Alary Muscles

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Transport of feed selenium to different tissues of bulls

British Journal Of Nutrition ◽

10.1079/bjn19910008 ◽

1991 ◽

Vol 66 (1) ◽

pp. 49-55 ◽

Cited By ~ 18

Author(s):

Päivi Ekholm ◽

Pertti Varo ◽

Pentti Aspila ◽

Pekka Koivistoinen ◽

Liisa Syrjälä-Qvist

Keyword(s):

Sodium Selenite ◽

Dry Matter ◽

Selenium Concentration ◽

Absorption Method ◽

Internal Organs ◽

Tissue Samples ◽

Different Types ◽

Basic Level ◽

Vitamin E Status ◽

Different Tissues

The effects of different types of Se supplementation on the selenium concentration of beef, bovine internal organs and some other tissues were studied. The animals (thirty-two bulls) were kept in four dietary groups from birth until to the age of 13–14 months, and fed on rations containing either 0.03 mg Se/kg (basic level in local feeds), 0.25 mg inorganic Se supplemented as sodium selenite, or 0.25 or 0.4 mg/kg plant Se in dry matter from feed produced by spraying with sodium selenite. Samples of four muscles and ten other tissues and organs were taken at slaughter. Se was determined by an electrothermal atomic absorption method. Se supplementation significantly increased the Se concentration of all tissue samples. The maximum response was caused by the diet containing 0.40 mg/kg plant Se. In muscles, this diet raised the Se concentration by a factor of 10–12. In other samples, the increment was 1.5–7.5 fold, depending on the type of tissue. In general, plant Se raised the Se level more effectively than inorganic Se. Se supplementation did not affect the vitamin E status of muscle tissue.

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Pilot Studies of Vibrations Induced in Perambulators When Moving on Different Surfaces

Applied Sciences ◽

10.3390/app11167746 ◽

2021 ◽

Vol 11 (16) ◽

pp. 7746

Author(s):

Gustaw Sierzputowski ◽

Radosław Wróbel ◽

Veselin Mihaylov ◽

Maciej Janeczek ◽

Marta Majewska-Pulsakowska ◽

...

Keyword(s):

Free Vibration ◽

Comfort Level ◽

Frequency Range ◽

Internal Organs ◽

Human Comfort ◽

Pilot Studies ◽

Iso Standard ◽

Resonance Frequencies ◽

Different Types ◽

Noise Vibration

The ergonomics of transport is a topic widely described in the literature. One of the fields of ergonomics that researchers are engaged in is vibrometry (both laser and accelerometry) of travel and its translation into NVH (Noise, Vibration and Harshness). However, so far, the influence of baby carriage movement on the generated vibrations has not been described in more detail. The topic seems to be particularly important considering occurrence of vibrations with significant amplitudes, whose frequency range can have a direct bearing on the resonance frequencies of the child’s internal organs. The article presents the results of research consisting in the measurement of vibrations to which an infant, lying in two different types of prams, may be exposed when being transported on different surfaces. The author’s measurement system, based on accelerometry, was used for the research. The obtained weighted RMS acceleration values not only exceeded human comfort level in all cases (according to ISO standard) but several times were in the range of the highest discomfort (>2 m/s2). Furthermore, the observed vibration frequency range (≈0–32 Hz) coincided with the frequencies of free vibration of organs and parts of the child’s body.

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The Role and Significance of Bioumoral Markers in Prostate Cancer

Cancers ◽

10.3390/cancers13235932 ◽

2021 ◽

Vol 13 (23) ◽

pp. 5932

Author(s):

Traian Constantin ◽

Diana Alexandra Savu ◽

Ștefana Bucur ◽

Gabriel Predoiu ◽

Maria Magdalena Constantin ◽

...

Keyword(s):

Prostate Cancer ◽

Blood Test ◽

Specific Antigen ◽

Digital Rectal Examination ◽

The United States ◽

Screening Tests ◽

Internal Organs ◽

Different Types ◽

Oncology Treatment

The prostate is one of the most clinically accessible internal organs of the genitourinary tract in men. For decades, the only method of screening for prostate cancer (PCa) has been digital rectal examination of 1990s significantly increased the incidence and prevalence of PCa and consequently the morbidity and mortality associated with this disease. In addition, the different types of oncology treatment methods have been linked to specific complications and side effects, which would affect the patient’s quality of life. In the first two decades of the 21st century, over-detection and over-treatment of PCa patients has generated enormous costs for health systems, especially in Europe and the United States. The Prostate Specific Antigen (PSA) is still the most common and accessible screening blood test for PCa, but with low sensibility and specificity at lower values (<10 ng/mL). Therefore, in order to avoid unnecessary biopsies, several screening tests (blood, urine, or genetic) have been developed. This review analyzes the most used bioumoral markers for PCa screening and also those that could predict the evolution of metastases of patients diagnosed with PCa.

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Constitutional diversity in the dimensions of internal organs of teenagers

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) ◽

10.21508/1027-4065-2019-64-2-94-99 ◽

2019 ◽

Vol 64 (2) ◽

pp. 94-99

Author(s):

V. O. Erkudov ◽

A. P. Pugovkin ◽

A. Ja. Volkov ◽

O. I. Musaeva ◽

P. A. Zhivtsova

Keyword(s):

Thyroid Gland ◽

Thyroid Hormones ◽

Ultrasound Examination ◽

Methodological Error ◽

Internal Organs ◽

Abdominal Organs ◽

Gender And Age ◽

Different Types ◽

Mosaic Distribution ◽

Selection Of

The anatomical dimensions of the internal organs are relatively stable and constitutionally determined. The connection between the somatotype and the size of the internal organs in adolescents - boys and girls - remains virtually unexplored. So, the purpose of this work is to compare the size of the internal organs separately in the group of young men and girls with lepto-, meso-and hypersome somatotype. The study involved 421 teenagers aged from 13 to 17 years: 225 boys and 196 girls. Their somatotypes were determined according to the patented method of V.A. Melnik, I.I. Salivon, N.I. Polina, and the sizes of abdominal organs and thyroid gland were determined using ultrasound morphometry. Their comparisons revealed the mosaic distribution of differences in the size of internal organs in children with different types of constitution. The authors discussed possible reasons of this difference: a methodological error in visualizing the size of internal organs, the influence of thyroid hormones, general biological and evolutionary factors, and the effect of narrow (in terms of gender and age) selection of the subjects. Thus, an orientation towards the constitutional features of the organism as a factor influencing the results of ultrasound examination of internal organs should be optional until the mechanisms and structure of these features are clarified in detail.

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The extinction time of a general birth and death process with catastrophes

Journal of Applied Probability ◽

10.1017/s0021900200116031 ◽

1986 ◽

Vol 23 (04) ◽

pp. 851-858 ◽

Cited By ~ 1

Author(s):

P. J. Brockwell

Keyword(s):

Laplace Transform ◽

Size Distribution ◽

Sufficient Conditions ◽

Necessary And Sufficient Conditions ◽

Death Process ◽

Extinction Time ◽

Birth And Death Process ◽

Different Types ◽

The Laplace Transform ◽

Necessary And Sufficient

The Laplace transform of the extinction time is determined for a general birth and death process with arbitrary catastrophe rate and catastrophe size distribution. It is assumed only that the birth rates satisfyλ0= 0,λj> 0 for eachj> 0, and. Necessary and sufficient conditions for certain extinction of the population are derived. The results are applied to the linear birth and death process (λj=jλ, µj=jμ) with catastrophes of several different types.

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Differentiating between different forms of moral obligations

Behavioral and Brain Sciences ◽

10.1017/s0140525x19002589 ◽

2020 ◽

Vol 43 ◽

Author(s):

Rajen A. Anderson ◽

Benjamin C. Ruisch ◽

David A. Pizarro

Keyword(s):

Moral Character ◽

Moral Obligations ◽

Different Types

Abstract We argue that Tomasello's account overlooks important psychological distinctions between how humans judge different types of moral obligations, such as prescriptive obligations (i.e., what one should do) and proscriptive obligations (i.e., what one should not do). Specifically, evaluating these different types of obligations rests on different psychological inputs and has distinct downstream consequences for judgments of moral character.

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Ultrastructural Investigations of the Contractile Filaments of Amoebae

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100050950 ◽

1974 ◽

Vol 32 ◽

pp. 188-189

Author(s):

P.L. Moore

Keyword(s):

Cytoplasmic Streaming ◽

Three Dimensional ◽

Freeze Fracture ◽

Amoeboid Movement ◽

Different Types ◽

Chemical Conditions ◽

Complete Interpretation

Previous freeze fracture results on the intact giant, amoeba Chaos carolinensis indicated the presence of a fibrillar arrangement of filaments within the cytoplasm. A complete interpretation of the three dimensional ultrastructure of these structures, and their possible role in amoeboid movement was not possible, since comparable results could not be obtained with conventional fixation of intact amoebae. Progress in interpreting the freeze fracture images of amoebae required a more thorough understanding of the different types of filaments present in amoebae, and of the ways in which they could be organized while remaining functional.The recent development of a calcium sensitive, demembranated, amoeboid model of Chaos carolinensis has made it possible to achieve a better understanding of such functional arrangements of amoeboid filaments. In these models the motility of demembranated cytoplasm can be controlled in vitro, and the chemical conditions necessary for contractility, and cytoplasmic streaming can be investigated. It is clear from these studies that “fibrils” exist in amoeboid models, and that they are capable of contracting along their length under conditions similar to those which cause contraction in vertebrate muscles.

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Study of the Molecular Architecture of Keratin Filaments by Electron Microscopy

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100053310 ◽

1982 ◽

Vol 40 ◽

pp. 118-119

Author(s):

U. Aebi ◽

P. Rew ◽

T.-T. Sun

Keyword(s):

Electron Microscopy ◽

Structural Organization ◽

Cell Types ◽

Structural Features ◽

Molecular Architecture ◽

The Past ◽

Keratin Filaments ◽

Different Types ◽

10 Nm Filaments ◽

Different Cell Types

Various types of intermediate-sized (10-nm) filaments have been found and described in many different cell types during the past few years. Despite the differences in the chemical composition among the different types of filaments, they all yield common structural features: they are usually up to several microns long and have a diameter of 7 to 10 nm; there is evidence that they are made of several 2 to 3.5 nm wide protofilaments which are helically wound around each other; the secondary structure of the polypeptides constituting the filaments is rich in ∞-helix. However a detailed description of their structural organization is lacking to date.

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