On the Regulation of Bilateral Symmetry in Plutei with Exchanged Meridional Halves and in Giant Plutei

Development ◽  
1957 ◽  
Vol 5 (1) ◽  
pp. 60-73
Author(s):  
Sven Hörstadius
Keyword(s):  
Sea Urchin ◽  
Frontal Plane ◽  
Vital Staining ◽  
Bilateral Symmetry ◽  
Sea Urchin Egg ◽  
The Subject ◽  
The Moment ◽  
Late Stages

The determination of bilateral symmetry in the sea-urchin egg has been the subject of investigations which have yielded contradictory results. The earlier literature was reviewed in 1936 (Hörstadius & Wolsky). It may therefore suffice to mention only the following points in this paper. The problem of whether or not the sperm induces the bilateral symmetry in the sea-urchin egg has not been solved by direct experimentation. By means of local vital staining opposite the point of sperm entrance Hörstadius (1928) concluded that there was no relation between the entrance point of the sperm and the position of the first furrow. The stain applied at the moment of fertilization soon became so diffuse that it was impossible to recognize the point of staining in late stages. It was at that time considered that the first furrow generally cut through the egg in either the median or the frontal plane, and only comparatively seldom obliquely to these planes (von Ubisch, 1925; Runnström, 1925; Hörstadius, 1928).

Protoplasmic Structure and Mitosis

1951 ◽  
Vol 28 (4) ◽  
pp. 434-444
Author(s):  
M. M. SWANN
Keyword(s):  
Structural Change ◽  
Sea Urchin ◽  
Active Substance ◽  
Mitotic Figure ◽  
Contractile Mechanism ◽  
Spindle Poles ◽  
Sea Urchin Egg ◽  
Protoplasmic Structure ◽  
New Material ◽  
The Moment

1. The mitotic figure of the sea-urchin egg is most strongly birefringent at metaphase. During anaphase this birefringence decreases considerably, but the spindle and asters both grow in size. These changes have been investigated quantitatively by constructing curves of retardation and coefficient of birefringence across the mitotic figure, using techniques described in an earlier paper. 2. The decrease of birefringence in the spindle starts at the equator, and then moves, in the course of a few minutes, to either pole. Only when the decrease has reached the spindle poles does it begin in the asters, where it moves outwards from the centres. 3. These changes resemble the movements of the chromosomes, which also start at the equator in metaphase, and move in separate groups to the poles during t anaphase. By examining single eggs in qaphase up to the moment of fixation, and then staining them to show the chromosomes, it is established that the regons of, decreasing birefringence actually correspond to the position of the chromosomes. 4. Since the chromosomes are too small to be the direct cause of the decrease in birefringence, it is concluded that they are producing the decrease indirectly by initiating a structural change in the spindle and asters. 5. The possible mechanisms for this change are discussed. It is concluded that the chromosomes must be releasing an active substance, for which the term ‘structural agent’ is suggested. 6. The growth of the mitotic figure takes the form, in the spindle, of an increase in length, and in the asters, of an increase in size. It is accompanied by an increase in coefficient of birefringence, though this is to some extent masked by the decrease in birefringence referred to earlier. 7. The increase in coefficient of birefringence affects the whole mitotic figure from the very beginning of anaphase, and is not therefore relatable to the position of the chromosomes. For this reason it might be due to a number of merent mechanisms, but as it starts at the same moment as the decrease in birefringence, it is tentatively assumed to be due to the release of a second ‘structural agent’. 8. The increase in coefficient of birefringence is probably due to the orientation of new material. The decrease is more Uely to be due to changes in molecular and micellar arrangement; it would be consistent with a contractile mechanism in the spindle. 9. The implications of these findings are discussed in a concluding section.

scholarly journals Tax monitoring as a method of digitalization of tax administration in the Russian Federation

2020 ◽  
pp. 18-39
Author(s):  
Elena Vladimirovna Berezina ◽  
Anna Sergeevna Balandina ◽  
Ol'ga Svyatoslavovna Belomyttseva
Keyword(s):  
Russian Federation ◽  
Historical Analysis ◽  
Tax Administration ◽  
The Status ◽  
The Subject ◽  
The Russian Federation ◽  
The Moment ◽  
Definition Of ◽  
Taxation System

This article presents a historical overview of the emergence of tax monitoring in the Russian Federation, as well as the analysis of its peculiarities within the context of trends of global taxation practice. Modern nations apply new approaches to tax administration, but commonly emerging and practically established ideas do not receive due scientific research. The object of this research is the process of digitalization of tax administration based on Russian and foreign experience. The subject of this research is the theoretical aspects of tax monitoring, as well as historical analysis of the emergence of a new format of interaction between tax administration and taxpayers in Russia and global practice. The goal of this work is to determine the role and importance of tax monitoring within taxation system of the Russian Federation, as well definition of tax monitoring as the means of digitalization of tax administration. The scientific novelty of this work consists in the comprehensive research of implementation of tax monitoring from the moment of its emergence in the global practice of taxation and determination of its essential features, which allowed concluding on incorrectness of legislator’s definition of tax monitoring as a form of tax control, and call for legislative definition of the concept of “tax administration”, as well as amending the Taxation Code of the Russian Federation for clarification of the status of taxpayers, who transitioned to the digital model of tax administration. The results of this research can be used in development of amendments to the legislation and criteria for assessing efficiency of tax monitoring.

scholarly journals Archaisms in D. Lyndsay’s play of the Early Modern English period “A Satire of the Three Estates”: problem of identification and stylistic assessment

Litera ◽  
2020 ◽  
pp. 11-19
Author(s):  
Alina Alekseevna Khavronich
Keyword(s):  
Early Modern ◽  
English Language ◽  
Literary Text ◽  
Literary Texts ◽  
Statistical Interpretation ◽  
Early Modern English ◽  
Approximate Frequency ◽  
The Subject ◽  
The Moment

The subject of this research is the method of identification and problem of statistical interpretation of archaic lexis in literary texts of the Early Modern English period, namely in D. Lyndsay’s play “A Satire of the Three Estates”. The article discusses the capacity of attracting the data from diachronic corpus and corpus-based dictionaries for determination of archaic elements in literary works of the XVI century. Leaning on the commentaries of reputable philologists of the Early Modern English period and modern research, the article explores the trends of relevant perception pertaining to introduction of archaisms into the literary text by the authors of that time. An algorithm is proposed for identification of outdated units in literary material, created on Scottish (considering the obsolescent character of this dialect), based on juxtaposition of the approximate frequency indexes of reproduction of the element in the Early Modern English and Scottish sections of Helsinki corpus, as well as data from the corpus-based dictionaries of Middle English and Scottish. For stylistic assessment of archaisms in the play of D. Lyndsay, the author applies the method of linguo-stylistic analysis, in which linguistic element is viewed from the contextual perspective. The scientific novelty is substantiated by the fact that for solution of the problem of analysis of archaisms in the texts of Early Modern English period, the author elaborates an algorithm that allows clarifying if a unit is obsolescent in a specific moment of development of the English language. It is established that the prevalent proportion of words in Lyndsay’s play was not archaic within the framework of Scottish dialect; and only few of the involved units were outdated at the moment of creation of text in the standard Early Modern English. The archaisms determined in the play allows stating the Lyndsay considered archaisms a part of elevated lexis. The practical values of this work is defined by the possibility to apply the proposed algorithm for detecting archaisms in any literary text of the Early Modern English period, as well as conduct stylistic assessment of archaisms from the perspective of the trends of their perception by the authors of the XVI century.

Light Side of Design: Professional Vector

2020 ◽  
pp. 23-33
Author(s):  
Elena A. Zaeva-Burdonskaya ◽  
Yuri V. Nazarov
Keyword(s):  
Professional Practice ◽  
Wide Spectrum ◽  
Scientific Basis ◽  
Design Culture ◽  
Interdisciplinary Nature ◽  
Educational Programmes ◽  
Design Activities ◽  
The Subject ◽  
Light Side

This article addresses one of the most actively developing types of design activities – light design. The article comprises quotes of the leading Russian and foreign light design specialists published over the previous five years, as well as the authors’ own conclusions. The thoughts quoted in the article are sometimes opposite to each other and reflect the wide spectrum of professional practice. They reflect the initial opinions of analysts and experts which are often diverging. All of the specialists point at the interdisciplinary nature of the new profession, which imposes additional load on a designer overloaded enough already by the scope and speed of the problems being solved nowadays. The discussion of the new profession of light designer initiated on the pages of professional publications is especially important in view of the development of professional standards and standards of design and architectural education, as well as creation of new educational programmes based on various approaches to the subject in technical and humanitarian institutions. The goal of this article is to introduce light design into the field of fully legitimate sections of design culture, to define the authentic scientific basis of the new creative profession, to initiate a foundation for self-determination of the new synthetic area, which materially affects the state of the profession as a whole and the life standards of a wide variety of consumers. In order to reach the set goal, a comparative and analytical method of study was selected, which allows studying the problem to a large extent and from all angles and finding the ways of overcoming the challenges emerging in the area of the new activity.

Assessment of sensitivity of the efficiency of regional tax spending towards investment attractiveness of the types of economic activity carried out by the residents of advanced development territory

2020 ◽  
pp. 98-110
Author(s):  
Evgeniya Mikhailovna Popova ◽  
Guzel Mukhtarovna Guseinova ◽  
Sergei Borisovich Milov
Keyword(s):  
Economic Activity ◽  
Socioeconomic Development ◽  
Federal District ◽  
Tax Incentives ◽  
Capital Investments ◽  
The Subject ◽  
Investment Process ◽  
The Impact ◽  
Advanced Development

The deficit of subnational budgets and deceleration capital investments in multiple Russian regions increase the relevance of research aimed at improvement of tax incentivizing practice of the regional investment process. The studies focused on determination of the impact of socioeconomic and institutional factors upon the efficiency of investment tax expenses obtained wide circulation within the foreign scientific literature. The subject of this article is the assessment of sensitivity of the efficiency of regional tax expanses towards investment attractiveness of the types of economic activity carried out by the residents of territories of advanced socioeconomic development, created in the subjects of Far Easter Federal District. The scientific novelty and practical values of this research consists in substantiation of the reasonableness of assessment of investment attractiveness of the types of economic activity that are stimulated by tax incentives. Methodology for assessing investment attractiveness is proposed and tested. The conclusion is made that in case of low investment attractiveness of the type of economic activity, which was planned to support by tax incentives, it is required to conduct and additional analysis to avoid unjustified tax expanses.

Crimes against marriage and family before Criminal Code 1968

2020 ◽  
Vol 15 (1-3) ◽  
pp. 44-59
Author(s):  
Lidia Peneva
Keyword(s):  
Criminal Code ◽  
Point Of View ◽  
Marriage And Family ◽  
Historical Method ◽  
Legal Method ◽  
The Subject ◽  
The Republic ◽  
Criminal Groups ◽  
The Moment ◽  
Structural Point

Crimes against marriage and family are a particular group of social relation­ships that the law has defended properly in view of the high public significance and value they enjoy. At the moment they are regulated in Chapter VI, Section I, of the specific part of the Penal Code the Repub­lic of Bulgaria. The subject matter of this Statement will, however, be the legisla­tive provisions concerning these criminal­ized acts in retrospect. The purpose of the study is to show by historical method and through the comparatively legal method the development of these criminal groups during the periods of various criminal laws in Bulgaria. This will also provide a basis for reflection on possible de lege ferenda proposals. This report from a structural point of view will be divided into three distinct points, marking each of the penal laws in the Republic of Bulgaria, which were in force before 1968.

PREDICTION OF THE EFFICIENCY OF RECONSTRUCTIVE INTERVENTIONS ON THE MAJOR NERVES OF THE FOREARM, DEPENDING ON THE DEFECT DURATION AND THE FOLLOWING REHABILITATION

2020 ◽  
pp. 77-88
Author(s):  
Дмитрий Валериевич Судаков ◽  
Олег Валериевич Судаков ◽  
Людмила Валентиновна Кретинина ◽  
Наталья Владимировна Якушева ◽  
Артём Николаевич Шевцов
Keyword(s):  
Nervous Tissue ◽  
Clinical Situation ◽  
Economic Importance ◽  
Important Data ◽  
Subsequent Period ◽  
Complete Restoration ◽  
Reconstructive Microsurgery ◽  
The Moment

Статья посвящена построению прогноза эффективности реконструктивных вмешательств на магистральных нервах предплечья в зависимости от протяженности дефекта нервной ткани и особенностей последующего периода реабилитации пациентов. Данная тематика является весьма актуальной, так как с каждым годом во всем мире наблюдается определенный рост случаев травм различного генеза магистральных нервных стволов, которые затем нередко приводят к временной нетрудоспособности и даже инвалидности пациентов. Реконструктивная микрохирургия многие десятилетия пытается решить целый ряд проблем аутотрансплантации нервных стволов и повысить ее общую эффективность. Но из-за определенных проблем связанных с финансированием, некоторые вопросы трансплантологии и реабилитации остаются нерешенными и в настоящий момент. Все это придает представленной работе важное значение не только медицинского, но и социально - экономического плана. Целью работы стала попытка построения прогноза восстановительных операций на нервной ткани, с учетом объема пораженных структур и периода реабилитации. Объектами исследования стало 180 больных, которым по той или иной причине, осуществлялась реконструктивная операция на одном из магистральных нервов предплечья. Все пациенты были разделены на 3 группы по 60 человек, в зависимости от протяженности дефекта магистрального нерва: до 4 см, от 4 до 8 см и от 8 до 12 см. Последующее разделение внутри каждой группы на подгруппы производилось в зависимости от определенного поврежденного нерва (лучевой, локтевой, срединный). В работе изучалось течение раннего послеоперационного воспалительного процесса, с определением бактериальной микрофлоры в ране. Изучались и отдаленные последствия оперативного вмешательства. Своеобразной новизной для данной тематики в целом, стало выявление последующего установления инвалидности пациентов. Кроме того, важные данные были получены и по срокам реабилитации и частичного или полного восстановления утраченных функций по срокам в зависимости от размеров восстанавливаемого дефекта и от наличия или отсутствия необходимой реабилитации. Полученные в работе данные могут представлять интерес не только для врачей хирургов и травматологов, но и для организаторов здравоохранения, позволяя производить прогнозы по выздоровлению пациентов в каждой определенной клинической ситуации The article is devoted to the construction of a forecast of the effectiveness of reconstructive interventions on the main nerves of the forearm, depending on the length of the defect in the nervous tissue and the characteristics of the subsequent period of rehabilitation of patients. This topic is very relevant, since every year all over the world there is a certain increase in cases of injuries of various origins of the main nerve trunks, which then often lead to temporary disability and even disability of patients. For many decades, reconstructive microsurgery has been trying to solve a number of problems of autotransplantation of nerve trunks and improve its overall efficiency. But due to certain problems associated with funding, some issues of transplantation and rehabilitation remain unresolved at the moment. All this gives the presented work important not only medical, but also socio - economic importance. The aim of this work was to attempt to predict restorative operations on the nervous tissue, taking into account the volume of the affected structures and the period of rehabilitation. The objects of the study were 180 patients who, for one reason or another, underwent a reconstructive operation on one of the main nerves of the forearm. All patients were divided into 3 groups of 60 people, depending on the length of the main nerve defect: up to 4 cm, from 4 to 8 cm, and from 8 to 12 cm. Subsequent division within each group into subgroups was performed depending on the specific damaged nerve ( radial, ulnar, median). The work studied the course of the early postoperative inflammatory process, with the determination of bacterial microflora in the wound. The long-term consequences of surgery were also studied. A peculiar novelty for this topic as a whole was the identification of the subsequent establishment of disability in patients. In addition, important data were obtained on the timing of rehabilitation and partial or complete restoration of lost functions in terms of timing, depending on the size of the restored defect and on the presence or absence of the necessary rehabilitation. The data obtained in this work may be of interest not only for surgeons and traumatologists, but also for healthcare organizers, allowing them to make predictions about the recovery of patients in each specific clinical situation

Application of hydrogenated butadiene-nitrile rubbers for products operated at high temperatures and in aggressive environments

2019 ◽  
pp. 129-136 ◽  
Author(s):  
E. A. Khorova ◽  
A. V. Myshlyavtsev
Keyword(s):  
Relative Elongation ◽  
Temperature Limit ◽  
Degree Of Unsaturation ◽  
Product Service ◽  
Nitrile Rubbers ◽  
The Subject ◽  
Maximum Content ◽  
Aging In Air ◽  
Hydrocarbon Media

The subject of the study were rubber mixtures based on hydrogenated butadiene-nitrile rubbers (HNBR) Therban, Zetpol, NBR-B with an acrylonitrile (AN) content of 34% to 49% and unsaturation of 0.9% to 22% with sulfuric, peroxide and sulfuric-peroxide cure systems. The purpose of the study was to determine the effect of the AN content and the degree of unsaturation of HNBR on the properties of rubbers in products designed for operation under the influence of fuels and oils at increased temperatures.The results of the determination of the mass swelling of rubbers in hydrocarbon media and the relative elongation in the process of thermal aging in air and in oil at increased temperatures are presented. The conclusion was made on the use of HNBR mixture with maximum content of AN (49%), with low (6%) and extremely low (0.9%) ODS content and sulfuric peroxide cure system to extend the product service temperature limit to 150°C.

Introduction

2018 ◽  
Author(s):  
Chakravarthi Ram-Prasad
Keyword(s):  
Philosophical Tradition ◽  
Phenomenological Tradition ◽  
The Third ◽  
Western Philosophical Tradition ◽  
The Subject ◽  
To Come

The Introduction outlines the various chapters. It then situates the question of ‘body’ in the modern Western philosophical tradition following Descartes, and argues that this leaves subsequent responses to come under one of three options: metaphysical dualism of body and subject; any anti-dualist reductionism; or the overcoming of the divide. Describing the Phenomenology of Merleau-Ponty as a potent example of the third strategy, the Introduction then suggests his philosophy will function as foil to the ecological phenomenology developed and presented in the book. Moreover, one approach within the Western Phenomenological tradition, of treating phenomenology as a methodology for the clarification of experience (rather than the means to the determination of an ontology of the subject) is compared to the approach in this book. Since classical India, while understanding dualism, did not confront the challenge of Descartes (for better or for worse), its treatment of body follows a different trajectory.

scholarly journals Cartilage Injuries and Posttraumatic Osteoarthritis in the Wrist: A Review

Cartilage ◽  
2021 ◽  
pp. 194760352110219
Author(s):  
Jonny K. Andersson ◽  
Elisabet Hagert ◽  
Mats Brittberg
Keyword(s):  
Literature Review ◽  
Radius Fractures ◽  
Osteochondral Autograft ◽  
Posttraumatic Osteoarthritis ◽  
Osteochondral Repair ◽  
Chondrocyte Implantation ◽  
Cartilage Injuries ◽  
The Subject ◽  
The Moment ◽  
And Cartilage

Objective: Focal cartilage injuries, and posttraumatic osteoarthritis (OA) in the wrist are likely common and a cause of wrist pain. To estimate the incidence of cartilage lesions and to understand the pathomechanisms leading to wrist cartilage injuries and OA, a literature review on the subject was performed combined with a presentation of one of the authors’ own experience. Design: This study includes a literature review of the topic. As a comparison to the review findings, the observations of one of the authors’ consecutive 48 wrist arthroscopies, were assessed. PubMed, Scholar, and Cochrane databases were searched using the keywords “cartilage injury AND wrist AND treatment” and “wrist AND cartilage AND chondral AND osteochondral AND degenerative OA.” :Result A total of 11 articles, including 9 concerning chondral and osteochondral repair and treatment and 2 regarding posttraumatic OA, were retrieved. The cartilage repair treatments used in these articles were drilling, osteochondral autograft, juvenile articular cartilage allograft, and chondrocyte implantation. One article displayed concomitant cartilage injuries in displaced distal radius fractures in 32% of the patients. The review of our findings from a 1-year cohort of wrist arthroscopies showed 17% cartilage injuries. Conclusion: There is a lack of knowledge in current literature on cartilage injuries and treatment, as well as posttraumatic OA in the wrist. Cartilage injuries appear to be common, being found in 17% to 32% of all wrist arthroscopies after trauma, but no guidelines regarding conservative or surgical treatment can be recommended at the moment. Larger prospective comparative studies are needed.

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