scholarly journals First person – Edismauro Freitas Filho

2021 ◽  
Vol 134 (9) ◽  

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Edismauro Freitas Filho is first author on ‘ RACK1 plays a critical role in mast cell secretion and Ca2+ mobilization by modulating F-actin dynamics’, published in JCS. Edismauro conducted the research described in this article while a PhD student in Maria Célia Jamur's lab at the Department of Cell and Molecular Biology and Pathogenic Bioagents, University of São Paulo, Brazil. He is now a postdoctoral fellow in the lab of Larissa Dias da Cunha at the Department of Cell and Molecular Biology and Pathogenic Bioagents, University of São Paulo, investigating the role of signaling proteins and specific lipids in the initial events of signal transduction, cytoskeleton rearrangement and LC3-associated phagocytosis during immune cell responses.

2020 ◽  
pp. 201-223
Author(s):  
Jeffrey D. Needell

This chapter analyzes the new cabinet’s position as well as the critical role of the Abolitionist leadership and provides a narrative of the legislation’s passage and its immediate aftermath. It begins with João Alfredo’s position and assessment of the situation, together with his cabinet appointments and parliamentary strategy, focusing on the reactionary threat. It goes on to emphasize the critical role of private relations with Rebouças and public Abolitionist support, the conflict between Abolitionist demands and Conservative emphasis on gradualism and indemnification, and Rebouças’s discreet legislative lobbying. It shows in detail how and why rural slavery’s collapse in São Paulo spread and what was its impact, how Rebouças’s position on abolition triumphed within the cabinet, and how Liberal and Abolitionist support for the cabinet solidified, and then concludes with an analytic narrative of the passage of the 13 May law abolishing slavery together with the immediate response of the Abolitionists.


Biology Open ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. bio054981

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Jessica Kabutomori is first author on ‘Water transport mediated by murine urea transporters: implications for urine concentration mechanisms’, published in BIO. Jessica is a masters student in the lab of Raif Musa Aziz at the Department of Physiology and Biophysics, University of São Paulo, investigating water transport across murine urea transporters UT-A2, UT-A3 and UT-B, towards the goal of better understanding the role(s) of these proteins in the kidney.


Check List ◽  
2016 ◽  
Vol 12 (6) ◽  
pp. 2020
Author(s):  
Gabriel Dalla Colletta ◽  
Vinicius Castro Souza ◽  
Thaís Elias Almeida ◽  
Fernanda Nunes Cabral ◽  
Ivan Jeferson Diogo ◽  
...  

We present  a list of vascular plants found in Legado das Águas, Reserva Votorantim, a private reserve having an area of approximately 35,000 ha that spans the municipalities of Tapiraí, Miracatú, and Juquiá, in the state of São Paulo, Brazil. The reserve is part of a complex of state-protected areas including Alto Ribeira Touristic State Park, Intervales State Park , Carlos Botelho State Park, Jurupará State Park, and Serra do Mar State Park. Together, these form an important and large area of continuous and well-preserved forest. Our study, which involved two main floristic surveys in March/April 2013 and April 2014, recorded 768 species, representing 131 families and 432 genera. The majority of species were angiosperms (619) representing 106 families and 370 genera. There were also two species of gymnosperms belonging to two genera in separate families; 147 species of ferns and lycophytes belonging to 23 families and 60 genera. In demonstrating the presence of almost 800 species of plants, of which 16 are threatened, our study highlights the importance of floristic surveys and the critical role of private protected areas in managing and preserving native flora.


2018 ◽  
Vol 10 (2) ◽  
pp. 85-113
Author(s):  
Nathalia Gleyce dos Santos Salazar

Resumo:  Apresenta-se uma discussão sobre o conhecimento e a tese dos três mundos no qual a interação entre estes nos aproxima da verdade do problema corpo-mente, tendo em vista, uma nova proposta de solução. O terceiro mundo é uma peça importante neste trabalho; sendo assim, analisaremos o que Popper designa como Mundo 3, em que ele consiste e o papel da linguagem como diferencial do ser humano. Apresentamos as críticas popperianas às correntes monistas e dualistas, ousando fazer uma crítica a Teoria do Conhecimento tradicional. Desta forma, a proposta apresentada por este filósofo da ciência diferencia-se de tudo que estava sendo feito até então, por isso, o interesse de apresentar essa abordagem pouco trabalhada de Popper. Palavras-chave: Conhecimento. Corpo-Mente. Mundo 3.Abstract: In this work, we present a discussion about knowledge and the theory of the three worlds in which the interaction between them approaches to the truth of the mind-body problem, in view of a proposed solution. The third world is an important piece in this work. Therefore, we will analyze what Popper describes as World 3, what it is and the role of language as a differential of human beings. We present Popper’s criticisms to the monistic and dualistic currents, daring to criticize the theory of traditional knowledge. Thus, the proposal of science presented by this philosopher differs from everything that was being done until then. This explains the interest in presenting this unusual approach to Popper.Keywords: Knowledge. Body-Mind.  World 3. REFERÊNCIASLEAL-TOLEDO, Gustavo . Popper e seu Cérebro. Revista da Faculdade de Letras. Série Filosofia, v. XXIII, p. 59-68, 2007.POPPER, Karl Raimund. A Lógica da Pesquisa Científica. Tradução de Leonidas Hegenberg e Octanny Silveira de Mota.  São Paulo: editora Cultrix. 2007.POPPER, Karl Raimund. Conhecimento Objetivo: uma abordagem evolucionária. Tradução de Milton Amado.  Belo Horizonte, Ed. Itatiaia Ilimitada. São Paulo, Ed. Da Universidade São Paulo, 1975._______.  O Conhecimento e o Problema Corpo –Mente. Tradução Joaquim Alberto Ferreira Gomes. Lisboa, Ed. 70. 1996.   _______. Conjecturas e Refutações: o desenvolvimento do conhecimento científico. Trad. Benedita Bettencourt. Ed. Livraria Almedina, 2006._______.  O Eu e Seu Cérebro. Karl Popper, Jonh C. Eccles;Tradução Silvio Meneses Garcia, Helena Cristina F. Arantes e Aurélio Osmar C. de Oliveira. – Campinas, SP: Papirus; Brasília, DF: Editora Universidade de Brasília. 1991.   _______. O Racionalismo Crítico na Política. Tradução de Maria da Conceição Côrte – Real. Brasília, Editora Universidade de Brasília, 2ª edição, 1994, 74p.SEARLE, John R. La construcción de la realidad social. Trad. Antoni Domènech. Barcelona: Paidós Ibérico, 1995.  


2021 ◽  
Vol 12 ◽  
Author(s):  
Yin-Fu Sun ◽  
Jiang Pi ◽  
Jun-Fa Xu

Exosomes are cell-derived nanovesicles carrying protein, lipid, and nucleic acid for secreting cells, and act as significant signal transport vectors for cell-cell communication and immune modulation. Immune-cell-derived exosomes have been found to contain molecules involved in immunological pathways, such as MHCII, cytokines, and pathogenic antigens. Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), remains one of the most fatal infectious diseases. The pathogen for tuberculosis escapes the immune defense and continues to replicate despite rigorous and complicate host cell mechanisms. The infected-cell-derived exosomes under this circumstance are found to trigger different immune responses, such as inflammation, antigen presentation, and activate subsequent pathways, highlighting the critical role of exosomes in anti-MTB immune response. Additionally, as a novel kind of delivery system, exosomes show potential in developing new vaccination and treatment of tuberculosis. We here summarize recent research progress regarding exosomes in the immune environment during MTB infection, and further discuss the potential of exosomes as delivery system for novel anti-MTB vaccines and therapies.


2020 ◽  
Vol 13 (12) ◽  
pp. dmm048199

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping early-career researchers promote themselves alongside their papers. Kim Landry-Truchon is first author on ‘Deletion of Yy1 in mouse lung epithelium unveils molecular mechanisms governing pleuropulmonary blastoma pathogenesis’, published in DMM. Kim is a research assistant in the lab of Lucie Jeannotte at Centre de recherche du CHU de Québec-Université Laval, Québec, Canada, investigating organ development and the regulatory networks involved. Nicolas is a research assistant in the same lab, investigating the role of master transcription factors during mouse development.


Clinics ◽  
2020 ◽  
Vol 75 ◽  
Author(s):  
Izabel Marcilio ◽  
Anna Miethke-Morais ◽  
Leila Harima ◽  
Amanda C. Montal ◽  
Beatriz Perondi ◽  
...  

2011 ◽  
Vol 4 (1) ◽  
pp. 91-104
Author(s):  
Huang Wen Hsien ◽  
Matheus Alberto Cônsoli ◽  
Antonio Carlos Giuliani

This article talks about purchase decision from small and medium retailers from Piracicaba Region, São Paulo State. The bibliographic and field research showed the main influence factors and decision criteria of small retailers for purchase, related to the choice between the traditional wholesale and the wholesale and retail outlet, which is a type of store that allows the wholesaler sales to sell to small or medium-sized retailers and for end consumers who are looking for the best price. The topics treated are the distribution channels, types of agents, the role of each one and the retailers' decision of purchasing. The exploratory research was applied to small and medium-sized retailers from Piracicaba Region, Sao Paulo State Countryside. From the eight case studies it was possible to identify the aspects considered relevant for retailers in the purchase decision and partner choice. Retailers were expressed by five attributes considered the most relevant, they are: convenience, variety, price, reliability and quantity.


2020 ◽  
Vol 10 (20) ◽  
pp. 520-540
Author(s):  
Eden Correia Carli ◽  
Jerusa Vilhena de Moraes

Nosso interesse neste artigo é refletir a respeito da importância do papel da argumentação para a aprendizagem em Geografia. Para isso, elencamos neste texto leituras e reflexões feitas através das pesquisas realizadas no campo da Argumentação Científica e das investigações que estamos desenvolvendo junto ao grupo de Pesquisa “Ensino de Geografia em Múltiplos Contextos”, da UNIFESP (Universidade Federal de São Paulo). Em nossas pesquisas temos articulado a importância do desenvolvimento da competência de argumentar cientificamente com o papel que as ciências humanas têm para sua efetivação. Desejamos relacionar esta articulação ao nosso campo de pesquisas em Geografia Escolar, na medida em que estamos interessados em apreender como a Geografia contribui para a tarefa de argumentar cientificamente e como ao argumentar os estudantes podem aprender Geografia. PALAVRAS-CHAVE Ensino de Geografia, Argumentação Científica, Natureza das Ciências.   ARGUES  CIENTIFICALLY: perspectives and investigation for school geography ABSTRACT Our interest in this article is reflect about the importance of the role of argumentation for learning in Geography. For that, we list in this text readings and reflections made through the researches carried out in the field of Scientific Argumentation and the investigations that we are developing in the research group “Teaching Geography in Multiple Contexts”, from the Federal University of São Paulo (UNIFESP). In our research we have articulated the importance of developing the competence to argue scientifically with the role that the human sciences have for its effectiveness. We wish to relate this articulation to our field of research in School Geography, inasmuch as we are interested in learning how Geography contributes to the task of arguing scientifically and how in arguing students can learn Geography. KEYWORDS Teaching of Geography, Scientific Argumentation, Nature of Sciences.


2015 ◽  
Vol 8 (1) ◽  
pp. 01-07
Author(s):  
Ruberval Leone Azevedo ◽  
Marcel Faria Lima

A citricultura no Brasil exerce um papel de grande importância econômica, social, gerando empregos, renda e desenvolvimento. O Brasil é o maior produtor mundial de citros, o Estado de Sergipe destaca-se em 5º lugar nacional em produção. Dentre os vários problemas fitossanitários enfrentados pela citricultura brasileira está a Clorose Variegada dos Citros (CVC), conhecida como amarelinho, causada pela bactéria Xylella fastidiosa Wells et al. A CVC foi identificada oficialmente no Brasil, em 1987, em pomares do Triângulo Mineiro e do Norte e Noroeste do Estado de São Paulo. No Nordeste, foi constatada em 1996 em Sergipe no município de Boquim, e em 1997 na Bahia, nos municípios de Rio Real e Itapicuru. O objetivo foi revisar a literatura sobre as espécies de cigarrinhas vetores da CVC, e verificar se ocorrem no estado de Sergipe. Os primeiros sintomas são vistos nas folhas, passam posteriormente para os frutos e acabam afetando toda a planta, e para serem percebidos pode levar entre 5 meses e 2 anos. Os principais vetores da X. fastidiosa em citros são as cigarrinhas da família Cicadellidae. No Brasil já foram confirmadas 12 espécies de cigarrinhas vetoras. Para o estado de Sergipe, são escassas a informações sobre Cicadellidae vetoras, os dados são limitados ao Litoral Norte da Bahia, com exceção de vaga citação sobre quatro gêneros (Oncometropia, Acrogonia, Dilobopterus e Homolodisca) e três espécies (Homolodisca ignorata Melichar, Acrogonia sp. e Homolodisca spottii Takiya, Cavichioli & McKamey). Citrus leafhoppers, Vectors of of Bacterium Xylella fastidiosa Wells et al.: Potential Pest of Citrus Crops in Sergipe State Abstract. The citrus industry in Brazil plays a role of great economic, social, generating jobs, income and development. Brazil is the largest producer of citrus, the State of Sergipe stands out in 5th place in national production. Among the many pest problems faced by Brazilian citrus is Citrus Variegated Chlorosis (CVC), known as the yellowing caused by the bacterium Xylella fastidiosa Wells et al. The CVC was officially identified in Brazil in 1987, in orchards of “Triângulo Mineiro” and North and northwest of the state of São Paulo. In the Northeast Region of Brazil, was found in 1996 in the municipality of Boquim Sergipe, and Bahia in 1997, the municipalities of Rio Real and Itapicuru. The aim was to review the literature on the species of leafhoppers vectors of CVC, and verify that occur in the state of Sergipe. The first symptoms are seen in the leaves, then go for the fruits and end up affecting the entire plant, and to be perceived can take between five months and two years. The main vectors of X. fastidiosa in citrus are the sharpshooters of the family Cicadellidae. In Brazil 12 sharpshooters species have already been confirmed. For the state of Sergipe, is scarce information about the Cicadellidae vectors, the data are limited to the northern coast of Bahia, except for vague quote about four genus (Oncometropia, Acrogonia, Dilobopterus and Homolodisca) and three species (Homolodisca ignorata Melichar, Acrogonia sp. and Homolodisca spottii Takiya, Cavichioli & McKamey).


Sign in / Sign up

Export Citation Format

Share Document