scholarly journals Removal efficacy of propolis/calcium hydroxide medicaments from the root canal

2021 ◽  
Vol 37 (7) ◽  
Author(s):  
Muhammad Adeel Ahmed

Objective: To compare the removal efficacy of propolis and calcium hydroxide medicaments from the root canal using manual irrigation with sodium hypochlorite. Methods: A randomized controlled trial was conducted at the Department of Restorative Dentistry and Endodontics, College of Dentistry, King Faisal University for two months. Thirty single-rooted upper or lower permanent anterior teeth with sound root and closed apex were selected. After cleaning and shaping of canal by protaper rotary, teeth were randomly divided into two groups. In group “A,” propolis paste was placed while calcium hydroxide was placed inside root canals in group “B,” followed by temporary restoration. After seven days, intracanal medicament was removed using 25 # K file and irrigated canal by 5 ml of 3.0% sodium hypochlorite. A final irrigation of 2-ml of 17% EDTA for three minutes followed by 1-ml of normal saline was performed. A diamond disc was used to cut the crowns of the teeth from cemento-enamel junction and divide the roots into two halves. These sectioned halves were then observed under a stereomicroscope at 7X magnification and analyzed using Adobe Photoshop. Magnetic lasso tool was used to calculate the percentage of residual medicament in the canals by comparing the pixel proportion of the medicament with the total pixel proportion of the canal. Paired t-test was used to see the difference in the number of remaining remnants between propolis and calcium hydroxide. A p-value of less than 0.5 was considered statistically significant. Results: A statistically significant difference (p-value < 0.001) was observed in the percentage of remaining remnants between propolis (23.22%) and calcium hydroxide (38.58%) after thorough irrigation with sodium hypochlorite. Conclusion: Propolis is superior to calcium hydroxide in terms of their removal potency from the root canal after thorough irrigation with sodium hypochlorite. doi: https://doi.org/10.12669/pjms.37.7.4241 How to cite this:Ahmed MA. Removal efficacy of propolis/calcium hydroxide medicaments from the root canal. Pak J Med Sci. 2021;37(7):---------. doi: https://doi.org/10.12669/pjms.37.7.4241 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

2021 ◽  
Vol 28 (11) ◽  
pp. 1611-1615
Author(s):  
Sadaf Minhas ◽  
Saqib Aslam ◽  
Muhammad Azhar Farooq ◽  
Ayesha Anwar ◽  
Farhan Zahoor ◽  
...  

Objective: To compare the Salbutamol alone and Ipratropium Bromide supplemented Salbutamol in children with exacerbation of asthma in terms of PEFR. Study Design: Randomized Controlled Trial. Setting: Pediatrics Emergency, KRL Hospital Islamabad. Period: 1st August 2016 to 31 January 2017. Material & Methods: Group A patients were given only Salbutamol (0.15mg/kg per dose with minimum 2.5 mg, maximum 5 mg/dose). Group B was given Ipratropium Bromide supplemented Salbutamol (250 mcg/dose for <20 kg while 500 mcg/dose for >20kg of Ipratropium Bromide with same dose of Salbutamol as prescribed for Group A). Baseline spirometry was performed on each patient and after measurement of baseline peak expiratory flow. The outcome was measured by Peak flow meter and reassessed at 60 minutes. Results: Comparison of salbutamol alone and ipratropium bromide supplemented salbutamol in children with exacerbation of asthma in terms of PEFR shows that 40.5 + 4.28 in Group-A and 59.5 +4.75 in Group-B, P-value was calculated as 0.0001, showing a significant difference between the two groups while the difference in increase was recorded as 19%. Conclusion: We concluded that salbutamol alone is significantly less effective when compared with Ipratropium Bromide supplemented Salbutamol in children with exacerbation of asthma in terms of PEFR.


2021 ◽  
Vol 15 (5) ◽  
pp. 906-909
Author(s):  
Zille Hyder Syed ◽  
Maryam Matloob ◽  
Rubina Qasim ◽  
Wafa Najeeb

Aim: To compare the frequency of infection and expulsion following insertion of IUCD immediate post casarean to that of interval insertion in parturient undergoing elective caesarean section Method: This Randomized controlled trial was conducted from 21 February to 20th August 2010. Results: It was observed that in immediate post cesarean group(Group A) expulsion rate was 8.1% and infection rate 7.2% where as in interval insertion group(Group B) expulsion rate was 10.9%and infection rate was 9.0%. The difference of expulsion rate was statistically significant in two groups (p value 0.491) i.e expulsion rate was proven to be significantly higher in interval insertion group than immediate trans cesarean insertion group. The difference of infection rate was not statistically significant between two groups (p value 0.623) although infection rate was found to be higher in interval insertion group but not clinically significant difference was found. Conclusion: Null hypothesis was rejected for expulsion rate of IUCD and a statistically significant increased expulsion rate was found in interval insertion group as compared to immediate post cesarean insertion group. Null hypothesis was accepted for infection rate after IUCD placement in two groups as no statistically significant increased infection rate was found between immediate post cesarean and interval insertion groups Keywords: Expulsion rate, infection rate,immediate post cesarean insertion,interval insertion.


2021 ◽  
Vol 15 (5) ◽  
pp. 1024-1027
Author(s):  
Asma Samreen ◽  
Aamir Waseem ◽  
Muhammad Azam ◽  
Itrat Hussain Kazmi ◽  
Aamir Bashir ◽  
...  

Background: Procedural sedation is required for multiple short duration procedures outside of the operating rooms especially in radiology and endoscopy suites. Intravenous anesthetic agent with rapid recovery profile is desirable in such circumstances. This study aims to compare two regimens of intravenous anesthetic agents. Aim: To compare the mean recovery time of propofol and midazolam with propofol alone for sedation in endoscopic retrograde cholangiopancreatography. Study Design: Randomized controlled trial. Settings: Department of Anesthesia, Shalamar Hospital, Lahore. Study Duration: June 2017 to December 2017. Methods: A total of 70 adult patients aged 20-60 years undergoing ERCP under sedation were included. Patients were given a combination of propofol and midazolam in group A while propofol alone was given in group B. After procedure, pts were transferred to recovery room and were followed for assessment of recovery time. Data were analyzed in SPSS vr 21, Independent t-test was applied & p-value ≤0.05 was considered statistically significant. Results: Significant difference was found in mean recovery time amongst both the groups. Mean recovery time in Group A (propofol and midazolam) was 19.29±4.50 minutes while in Group B (propofol alone) was 26.66±3.70 minutes showing statistically significant result with p-value = 0.0001. Conclusion: We conclude that mean recovery time with propofol plus midazolam is shorter as compared to propofol alone for sedation in ERCP. Keywords: Propofol, midazolam, sedation outside operation theatre.


2021 ◽  
Vol 9 (01) ◽  
pp. 984-990
Author(s):  
Malavika Mohan ◽  
◽  
Meenakshi R. Verma ◽  
Ashish K. Jain ◽  
Rahul D. Rao ◽  
...  

Context: Use of root canal solvents has increased the success rate of endodontic retreatment and it has made the procedure faster and simpler. Aims: During retreatment, a solvent facilitates the removal of obturation material and root canal sealer by softening it, so as to obtain a root canal free of debris and microorganisms. Hence an invitro study was done to evaluate and compare the dissolving effect of RC Solve, Eucalyptus oil and G-sol on AH Plus Root Canal Sealer. Methods and Material: Thirty standardized stainless-steel rings filled with AH Plus sealer manipulated according to manufacturers instructions were prepared and placed ten minutes for complete setting in an incubator at 37°C for 48 hours and weighed to obtain the initial weight. The samples were divided into three equal groups of 10 each and immersed in RC Solve, Eucalyptus oil and G-sol for 10 minutes and dried in an incubator at 37°C for 24 hours and weighed again for final weight. The amount of sealer lost was determined by calculating the difference between initial and final weight. Results: The dissolving effect of AH Plus sealer on all three solvents showed a marked amount of weight loss (p<0.05). The best dissolving capability on AH Plus sealer was exhibited by Eucalyptus oil followed by RC Solve and least for G-Sol. The result of the ANOVA with a p-value of 0.004 indicated a significant difference of weight change of AH Plus sealer after immersion into RC Solve, Eucalyptus Oil and G-Sol. Conclusions: Based on the findings of this study, it was concluded that Eucalyptus oil has a slightly better solvent effect.


Author(s):  
Juzer Shabbir ◽  
Fazal Qazi ◽  
Waqas Farooqui ◽  
Shahbaz Ahmed ◽  
Tazeen Zehra ◽  
...  

Propolis is a potent anti-microbial and natural anti-inflammatory by-product obtained from the beehive. Studies have demonstrated the superior biocompatibility and anti-microbial properties of propolis as compared to calcium hydroxide. However, its effect on postoperative endodontic pain is unknown. Therefore, this study aimed to investigate the impact of Chinese propolis paste as an intracanal medicament on postoperative endodontic pain intensities compared with calcium hydroxide (control) at different time intervals in necrotic teeth with periapical radiolucency. Eighty patients with single-rooted necrotic teeth with visible periapical radiolucency were recruited and randomly allocated to either the calcium hydroxide or propolis groups. After chemo-mechanical preparation and intracanal medicament insertion, patients were given the VAS (visual analogue scale) to record pain scores. Inter-group data were compared and analyzed using two-way repeated measure ANOVA (Bonferroni test). A p-value of < 0.025 was considered significant. In total, >78% of the patients experienced no or only mild post-operative pain in both the groups at all time intervals, without any significant difference in pain scores between the two groups (p > 0.025). An overall flare-up rate of 14.8% was found. The results suggest that either of these medicaments can be used as an inter-appointment medication for the prevention of postoperative pain in necrotic cases.


2019 ◽  
Vol 26 (07) ◽  
pp. 1197-1202
Author(s):  
Hajra Shuja ◽  
Mehmood Ali Shah ◽  
Sadaf Bokhari

Background: Laparoscopic cholecystectomy is a standard treatment for cholelithiasis. It is a safe and effective treatment in many cases. General anesthesia has a high incidence for PONV. But anti-emetic drugs can help in preventing PONV. Objectives: To compare the efficacy of ondansetron and metoclopramide in patients undergoing laparoscopic cholecystectomy under general anesthesia. Study Design: Randomized controlled trial. Setting: Department of Anaesthesia, Sheikh Zayed Hospital, Lahore. Period: 6 months i.e. from 15-2-2017 to 15-8-2017. Material & Methods: The patients were divided into two groups. Ondansetron was given to group A patients within 15 minutes of induction, and metoclopramide to group B patients within 15 minutes of induction. Then patients were shifted to the ward after surgery and followed-up for 24 hours for assessment of PONV. All the data was entered and analyzed on SPSS version 20. Results: The mean age of patients in group A was 38.40±12.07 years and in group B was 42.63±11.77 years. The efficacy achieved in 53 were from group A and 39 were from group B Statistically significant difference was found between the study groups i.e. p-value=0.003. Conclusion: Ondansetron showed significantly better efficacy than metoclopramide in preventing PONV after laparoscopic cholecystectomy under general anesthesia.


2013 ◽  
Vol 749 ◽  
pp. 211-214
Author(s):  
Hui Xiao Yang

To evaluate the therapeutic efficacy of calcium hydroxide as an intra canal dressing on controlling postoperative pain and swelling in patients suffering from residual pulpitis. 118 patients with residual pulpitis in their anterior teeth participated in this study. These patients were randomly divided into two groups (group A and group B) of fifty-nine. All teeth were treated with root canal therapy with a two-visit approach. The patients in group A were treated with calcium hydroxide as an intra canal dressing , and in group B using formocresol as an intra canal dressing. All of the patients were followed up for 72 h after each treatment session. The postoperative incidence and severity of pain and swelling were recorded. The data were analyzed by chi-square test and variance analysis. After the first visit, the incidence and severity of pain and swelling showed to be higher in group B and lower in group A. These differences were statistically significant. After the second visit, the incidence and severity of pain and swelling showed to be still higher in group B and lower in group A. But there were no significant difference. Conclusion It is concluded that calcium hydroxide as an intra canal dressing could be effective to decrease the postoperative pain and swelling. It is recommended to use calcium hydroxide as an inter-appointment dressing in teeth with residual pulpitis.


Author(s):  
Udayanila Thangavel ◽  
Harish Narasing Katakdhond ◽  
Deepak Dalmia ◽  
Narsinha Davange ◽  
Parth Patni ◽  
...  

<p class="abstract"><strong>Background:</strong> Otosclerosis presents as conductive hearing loss, stapedotomy is the treatment for otosclerosis, and different sizes of piston diameter are available for the procedure. Aims and objectives were to study and compare hearing improvement between the 0.4 and 0.6 mm sizes of teflon piston in stapedotomy.</p><p class="abstract"><strong>Methods:</strong> It was a prospective randomized controlled trial. Patients fulfilling inclusion criteria were subjected for small fenestra stapedotomy. Patients were divided into two groups after randomization into group A (with 0.4 mm piston diameter) and group B (with 0.6 mm piston diameter). The hearing outcome with standard audiological assessment was performed at one month and six months postoperatively.  </p><p class="abstract"><strong>Results:</strong> Comparison of 1 month AB gap among the patients with 0.4 mm piston and 0.6 mm piston showed that there was no statistically significant difference among both the groups of patients (independent t test p value=0.699). Comparison of 6 month AB gap among the patients with 0.4 mm piston and 0.6 mm piston showed that there was no statistically significant difference among both the groups of patients (independent t test p value=0.54).</p><p class="abstract"><strong>Conclusions:</strong> There was no significant difference in hearing improvement among the individual methods (piston size 0.4 and 0.6) with each other both in 1 month post-operative and 6 month post-operative follow up. Hence, we conclude that there is no relevance of different diameter of teflon piston prosthesis (0.4 mm versus 0.6 mm) as far as hearing outcome is concerned.</p>


2021 ◽  
Vol 37 (3) ◽  
Author(s):  
Rashida Parveen ◽  
Mehnaz Khakwani ◽  
Sobia Tabassum ◽  
Sajjad Masood

Objectives: This study was planned with an aim to find out the effectiveness of oral versus vaginal micronized progesterone for the treatment of threatened miscarriage. Methods: This randomized controlled trial was conducted at The Department of Obstetrics and Gynaecology, Nishtar Hospital Multan, from August 2019 to January 2020. A total of 136 pregnant women, aged 18 to 45 years having vaginal bleeding were included and divided into two groups (68 women in each group). Participants in the Group-A were given oral micronized progesterone as 200mg twice a day while Group-B participants were given vaginal progesterone suppository 400mg once a day. All women were followed up until 20th week of their pregnancy. Outcome was labeled as prevention of miscarriage if woman had no bleeding per vagina and pregnancy went beyond 20th weeks of gestation. Results: In a total of 136 women enrolled, mean age was noted to be 30.85+3.34 years. Overall, mean gestational age was noted to be 9.3+2.7 weeks. A total of 98 women (49 in each group) completed the follow up and were included in the final analysis regarding outcome. Among Groups-A, 45 (91.8) had prevention of miscarriage while 4 (9.2%) had miscarriage in comparison to 36 (73.5%) in Group-B had prevention of miscarriage whereas 13 (26.5%) had miscarriage and this difference was statistically significant in between the both study groups as women in Group-A had significantly better outcome in terms of prevention of miscarriage. (P value = 0.0164). Conclusion: The use of oral micronized progesterone was found to be significantly more effective than vaginal progesterone in women with threatened miscarriage. doi: https://doi.org/10.12669/pjms.37.3.3700 How to cite this:Parveen R, Khakwani M, Tabassum S, Masood S. Oral versus Vaginal Micronized Progesterone for the treatment of threatened miscarriage. Pak J Med Sci. 2021;37(3):---------. doi: https://doi.org/10.12669/pjms.37.3.3700 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Esculapio ◽  
2021 ◽  
Vol 17 (1) ◽  
pp. 39-44
Author(s):  
Faridah Sohail ◽  
Lala Rukh Bangash ◽  
Waqar Azim ◽  
Farah Arshad ◽  
Anum Anwar ◽  
...  

Objective: To compare the efficacy of oral ketamine with oral dexmedetomidine for providing adequate analgesia for change of dressing in burn patients in burn dressing room. Methods: This randomized controlled trial was carried out in Jinnah Burn and Reconstructive Surgery Center, Lahore, from April 2019 to September 2019 after getting the approval from the Ethical Committee of Jinnah Hospital / Allama Iqbal Medical College, Lahore. 80 patients between 20 to 50 years, with 1st and 2nd degree burns and 20 to 40% of total body surface area involved were allocated in two groups A and B. The patients in group A received oral ketamine at a dose of 5mg/kg in 15 ml of water 30 mins while those in group B received dexmedetomidine, 4 ug/kg orally, in 15 ml of water 30 mins before the start of dressing change. The change of dressing was carried out with continuous vital monitoring. Pain was assessed via visual analogue scale (VAS) and sedation via Ramsay sedation score. All the observations were recorded on the predesigned proforma. SPSS version 21 was used for data analysis. Result: The baseline mean VAS score of patients in group A was 7.67 + 0.55 and in group B was 7.70 + 0.57 (p value = 0.799). Significant decrease in pain score in both groups was noted after 30 mins of drugs administration (p=0.000). Also a significant difference in pain scores was seen between the two groups (p< 0.05), with the patients in group A having lower pain scores as compared to patients in group B. Conclusion: both ketamine and dexmedetomidine provide adequate analgesia for the change of burn dressing when administered orally with ketamine providing better analgesic state as compared to dexmedetomidine. Key Words: Burn, ketamine, dexmedetomidine, analgesia. How to cite: Sohail F., Bangash R.L., Azim W., Arshad F, Anwar A., Niazi K.A. Analgesia for the Change of Dressing in Burn Victims: A Comparison between Oral Ketamine and Oral Dexmedetomidine. Esulapio 2021;17(01):39-44


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