Factors influencing non-adherence to opioids in cancer patients: a mixed-methods cross-sectional study

Background: Strong opioids are mainly utilized to attenuate pain in cancer patients. Adherence to analgesic drugs significantly promotes adequate pain management and improves quality of life. We aimed to identify the factors influencing non-adherence to strong opioids in cancer patients. Methods: A descriptive, cross-sectional, two-phased, mixed methods design was conducted prospectively to evaluate a cohort of 101 cancer patients who are currently prescribed strong opioids from a pain clinic in Thailand between January and March 2018. Participants were asked to complete a questionnaire that included the following sections: general characteristics; the Medication Taking Behavior in Thai (MTB-Thai) for assessing adherence to medications; and factors influencing nonadherence, which were analyzed using multivariate logistic regression. In addition, face-to-face in depth interviews were conducted with patients showing non-adherence to strong opioids (MTB-Thai score ≤21) and analyzed using thematic content analysis. Results: Of 101 cancer pain patients that completed the questionnaire, 39.6% showed non-adherence to strong opioids. Illness understanding (P=0.047) and the use of more than three types of pain medication (P=0.032) were significant factors influencing non-adherence. Qualitative analysis indicated that fear of long-term outcomes, opioid side effects, ineffective pain control, attempts to make the regimen more acceptable, poor understanding, and non-acceptance of disease related to non-adherence. Conclusion: Non-adherence to opioids for cancer patients is a common problem. Awareness of patient factors, medication-related factors, and illness-related factors will provide the knowledge and adequate advice that may enhance adherence to medications.

Download Full-text

Factors associated with delay in presentation among patients for oral cancer

Journal of Comparative Effectiveness Research ◽

10.2217/cer-2019-0067 ◽

2019 ◽

Vol 8 (12) ◽

pp. 1003-1071

Author(s):

Xinyan Zhang ◽

Dongling Liu ◽

Hongmei Dong ◽

Yuxiang Li ◽

Ye Zhang ◽

...

Keyword(s):

Oral Cancer ◽

Cancer Patients ◽

Lower Risk ◽

Cross Sectional Study ◽

Cancer Knowledge ◽

Sectional Study ◽

Cross Sectional ◽

Factors Associated ◽

Factors Influencing ◽

Oral Cancer Patients

Aim: This study aimed to determine factors that influence delay in presentation among oral cancer patients. Materials & methods: A cross-sectional study with 128 Oral cancer patients receiving treatment from the Hospital of Stomatology, at Jilin University, in China, was conducted. Results: A total of 78 patients delayed seeking treatment for more than 3 weeks after noticing symptoms of oral anomaly. Patients who were male, farmers (Odds ratio [OR] = 2.617; 95% CI: 1.90–3.64), or currently smoking (OR = 4.651; 95% CI: 1.21–9.46), were more likely to delay. Patients alerted to the problem at a physical exam had much lower risk of delay than patients who discovered the disease independently (OR = 0.029; 95% CI: 0.01–0.30). Higher coping style scores (OR = 0.747; 95% CI: 0.47–1.18) and oral cancer knowledge scores (OR = 0.886; 95% CI: 0.60–2.01) were significantly correlated with shorter delays. Conclusion: Delay in presentation may be achieved through regular oral health screening and improved public education about factors influencing delay.

Download Full-text

Factors influencing health-related quality of life of families of cancer patients: A cross-sectional study in Japan

Journal of Psychosomatic Research ◽

10.1016/j.jpsychores.2018.03.078 ◽

2018 ◽

Vol 109 ◽

pp. 111

Author(s):

H. Kanemura ◽

U. Yamada ◽

T. Iwata ◽

O. Takahashi ◽

D. Ohta

Keyword(s):

Quality Of Life ◽

Cancer Patients ◽

Cross Sectional Study ◽

Health Related Quality ◽

Sectional Study ◽

Cross Sectional ◽

Factors Influencing ◽

Related Quality ◽

Health Related

Download Full-text

Bereaved relatives’ views about participating in cancer research

Palliative Medicine ◽

10.1177/0269216311405091 ◽

2011 ◽

Vol 26 (4) ◽

pp. 379-383 ◽

Cited By ~ 30

Author(s):

Jonathan Koffman ◽

Irene J Higginson ◽

Sue Hall ◽

Julia Riley ◽

Paul McCrone ◽

...

Keyword(s):

Cancer Patients ◽

Large Scale ◽

Cross Sectional Study ◽

Postal Questionnaire ◽

Next Of Kin ◽

Cross Sectional ◽

Face To Face ◽

Therapeutic Value ◽

Large Scale Survey ◽

New Evidence

Background: Bereaved relatives are considered to be a vulnerable group and there is debate as to whether it is ethical to engage them in research at a time that can be difficult for them. Aim: We conducted a cross-sectional study using cognitive interviewing with the aim of exploring the acceptability of a mortality follow-back survey among bereaved relatives of recently deceased cancer patients to inform the development of a large-scale survey about end-of-life care. Results: Thirty-three next-of-kin of recently deceased cancer patients were invited to participate in a face-to-face interview, or to complete a postal questionnaire. At the end, they were asked about their views of engaging in the study. Nine bereaved relatives participated in a face-to-face interview and 11 completed the postal questionnaire. Eleven relatives reported it was helpful to take part in the study; of these, six did not consider it distressing, and five stated whilst it had been distressing it had been helpful. Thoughts about bringing back memories, altruism and therapeutic value emerged. Conclusions: We have new evidence that although engaging in follow-back surveys can evoke distress, many participants report it to be a positive experience. We therefore believe that this approach is acceptable when conducted sensitively.

Download Full-text

A Cross Sectional Study to Assess Musculoskeletal Disorders among Bangladeshi Cycle Rickshaw Pullers and its Association with Ergonomics and Work-related Factors

Journal of Anesthesia & Pain Medicine ◽

10.33140/japm.04.01.05 ◽

2019 ◽

Vol 4 (1) ◽

Keyword(s):

Musculoskeletal Disorders ◽

Significant Relationship ◽

Weight Bearing ◽

Sampling Technique ◽

Cross Sectional Study ◽

Sectional Study ◽

Related Factors ◽

Cross Sectional ◽

Face To Face ◽

Work Related

Background: Musculoskeletal Disorders (MSDs) are the most common and largest category of work-related illness seen both in a developed & developing country. Purpose: The purpose of the study to assess the MSDs of Cycle Rickshaw (CR) Pullers & to find out the significance between MSDs with related variables. Material & Methods: A descriptive cross-sectional study was conducted among 136 CR Pullers residing in the Dhaka Metropolitan city. Purposive sampling technique was used where data were collected by a structure administered questionnaire with face to face interview & data was analyzed by SPSS (Version 20). Results: Results indicated that the prevalence of MSDs was 91% where upper back, lower back, leg & calf muscle, & knee joint was the more prevalent site. Some ergonomics and work related factors are responsible for developing MSDs. However, there was a significant relationship between MSDs with weight bearing (P<0.05) & daily rickshaw pulling time (p<0.05). In addition, an extremely high significant relationship found between MSDs with age (p<0.001) and BMI (p<0.001). Conclusion: It is concluded that MSDs among CR pullers were extremely high. Awareness of ergonomics and work-related factors might help to prevent and reduce the prevalence of MSDs among CR pullers.

Download Full-text

Evaluation of sexual function and its related factors in women with breast cancer undergoing chemotherapy referred to Iran-Mehr Medical Center in Birjand, 2018

Journal of Birjand University of Medical Sciences ◽

10.32592/jbirjandunivmedsci.2020.27.4.105 ◽

2020 ◽

pp. 366-375

Keyword(s):

Breast Cancer ◽

Sexual Function ◽

Cancer Patients ◽

Medical Center ◽

Cross Sectional Study ◽

Breast Cancer Patients ◽

Related Factors ◽

Cross Sectional ◽

Factors Affecting ◽

Age Of Marriage

Background and Aim: The Breast cancer is very common. These patients develop sexual dysfunction following chemotherapy. The aim of this study was to evaluate the effect of chemotherapy in breast cancer patients on their sexual function. Materials and Methods: This descriptive-analytical cross-sectional study was performed on patients with breast cancer referred to Iran-Mehr Medical Center in winter 2018 undergoing chemotherapy. 119 patients were enrolled in the study under census. The Rosen’s Sexual Function Questionnaire was used to collect data. Data were analyzed by using SPSS (Version 16) and Smirnov-Kolmogorov, Kruskal-Wallis and Mann-Whitney tests at the significant level of (P<0.05). Results: In terms of sexual function, the lowest score was 2.40 and the highest score was 14.90. In the study of sexual function components, patients were in the worst condition in terms of pain, 0.84±0.75 and humidity 0.85±0.73. The mean scores of other components included orgasm 1.13±0.64, irritability 1.05±0.84, satisfaction 1.23±0.30 and sexual desire 1.66±0.66, respectively. The only factor affecting sexual function Location, age of marriage and age of patients. Conclusion: The score of sexual function was less than the minimum; the most disorders were recorded for the components of pain and humidity. Factors affecting sexual function were included: location, years of menopause, type of treatment, age of patients and years of marriage. It is recommended that the sexual status of breast cancer patients be evaluated before and during treatment and that the necessary training be provided to inform patients about this disorder and the necessary treatments to improve sexual function.

Download Full-text

Surgery decision conflict and its related factors among newly diagnosed early breast cancer patients in China: A cross‐sectional study

Nursing Open ◽

10.1002/nop2.791 ◽

2021 ◽

Author(s):

Han Tang ◽

Shang Wang ◽

Shiqi Dong ◽

Ruofei Du ◽

Xiao Yang ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Early Breast Cancer ◽

Cross Sectional Study ◽

Newly Diagnosed ◽

Breast Cancer Patients ◽

Sectional Study ◽

Decision Conflict ◽

Related Factors ◽

Cross Sectional

Download Full-text

Components and Related Factors of Nursing Interventions for Improving Resilience in Cancer Patients Undergoing Chemotherapy

Healthcare ◽

10.3390/healthcare9030300 ◽

2021 ◽

Vol 9 (3) ◽

pp. 300

Author(s):

Shiena Shimada ◽

Michiko Aoyanagi ◽

Naomi Sumi

Keyword(s):

Cancer Patients ◽

Cross Sectional Study ◽

Nursing Interventions ◽

Chemotherapy Treatment ◽

Related Factors ◽

Cross Sectional ◽

Outpatient Chemotherapy ◽

Self Help ◽

Resilience Scale

Resilience is considered an effective concept for cancer patients, but nursing interventions for improving resilience have not been studied adequately yet. We aimed to explore the components and related factors of nursing interventions for promoting resilience among cancer patients receiving chemotherapy (NIPRPC). This cross-sectional study included 68 facilities from 396 cancer hospitals in Japan. Participants were 377 nurses who worked at the outpatient chemotherapy center or cancer ward. They completed self-administered questionnaires including the NIPRPC items and Resilience Scale for Nurses, etc. We conducted factor, correlational, and regression analysis. Based on the exploratory factor analysis, six-dimensional factor components: “Support for patients during the present situation and increasing their self-affirmation”, “Support for self-help”, “Support for utilizing the cancer medical team”, “Support for obtaining family cooperation”, “Support for maintaining regular lifestyle during chemotherapy”, and “Support for interacting with cancer patients and utilizing necessary information”. The strong related factors for all six factors were the resilience of the nurses and the number of collaborations with multiple occupations. Our findings will help nurses improve the psychosocial quality of life of cancer patients and address their needs related to cancer chemotherapy treatment.

Download Full-text