High preterm birth at Cipto Mangunkusumo Hospital as a national referral hospital in Indonesia

Background: Preterm birth is the leading direct that causes neonatal death. Indonesia was listed as one of the countries with the greatest number of preterm birth in 2010. This study aims to identify the prevalence and the potential risk factors of preterm birth among women underwent delivery in Cipto Mangunkusumo Hospital, an Indonesian national reference hospital.Methods: This retrospective cohort study involved 2,612 women who delivered between January and December 2013. Any clinical data which related to the potential risk factors and outcomes were recorded. The data were managed using chi-square for bivariate analysis and t-test or Mann-Whitney for numerical data followed by multiple logistic regression for multivariate analysis in SPSS version 20.0.Results: Preterm birth affected 1,020 of 2,616 pregnancies (38.5%). Non-booked patients increased nearly twice risk for preterm delivery (OR 1.89, 95% CI 1.37–2.61). While women with singleton pregnancy (OR 0.17, 95% CI 0.12–0.25), head presentation (OR 0.75, 95% CI 0.63–0.89), and regular ANC (OR 0.67, 95% CI 0.54–0.84) had lower risk for preterm birth. Apgar score, birthweight, and mode of delivery were significantly different between the pre-term group and the full-term group.Conclusion: Prevalence of preterm birth in Cipto Mangunkusumo Hospital was approximately 2.5 times higher compared to the national number. Several factors reducing preterm birth rate include singleton pregnancy, head presentation, and regular ANC.

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Prevalence of Human Cystic Echinococcosis in Rio Negro Province, Argentina and Direct Risk Factors for Infection

10.21203/rs.3.rs-260421/v1 ◽

2021 ◽

Author(s):

Leonardo Uchiumi ◽

Guillermo Mujica ◽

Daniel Araya ◽

Juan Carlos Salvitti ◽

Mariano Sobrino ◽

...

Keyword(s):

Risk Factors ◽

Potential Risk ◽

Rural Areas ◽

Cystic Echinococcosis ◽

Significant Risk ◽

Prevalence Ratio ◽

Bivariate Analysis ◽

Rio Negro ◽

Potential Risk Factors ◽

Current Address

Abstract Background: Cystic echinococcosis (CE) is a parasitic zoonosis caused by infection with the larval stage of Echinococcus granulosus sensu lato This study investigated the prevalence and potential risk factors associated with human CE in the towns and rural areas of Ñorquinco and Ramos Mexia, Rio Negro province, Argentina. Methods: In order to detect abdominal CE cysts, we screened 892 volunteers by ultrasound and investigated potential risk factors for CE using a standardized questionnaire. Bivariate and multivariate analyses were used to estimate the Prevalence Ratio (PR) and their 95% CIs of the association between CE and the factors investigated. Results: Abdominal CE was detected in 42/892 screened volunteers (4.7%, CI 3.2-6.1), only two of who being under 15 years of age. Thirteen CE (30.9%) cases had 25 cysts in active stages (CE1, CE2, CE3) The most relevant risk factors identified in the bivariate analysis included: live in rural area (p=0.003), age >40 years (p=0.000), drinking always water of natural source (p=0.007), residing in rural areas during first five years of life (p=0.000) and live more than 20 years at your current address (p=0.013). In the multivariate model, statistically significant risk factors were: frequently touch dogs (p=0.012), residing in rural areas during first five years of life (p=0.004), smoking (p=0.000), age > 60 years (p=0.002) and live in rural areas (p=0.017).Conclusions: our results point toward infection with CE being acquired since childhood and with constant exposure throughout life, especially in rural areas with a general environmental contamination

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Incidence of Calf Morbidity and Its Predictors in North Shewa, Amhara, Ethiopia

Veterinary Medicine International ◽

10.1155/2020/6490710 ◽

2020 ◽

Vol 2020 ◽

pp. 1-10 ◽

Cited By ~ 1

Author(s):

Rahma Mohammed ◽

Hailemariam Kefyalew ◽

Dawit Kassaye

Keyword(s):

Risk Factors ◽

Potential Risk ◽

Linear Models ◽

Livestock Production ◽

Economic Losses ◽

Chi Square ◽

Exact Test ◽

Mixed Crop ◽

The Face ◽

Potential Risk Factors

Calf morbidity is an important productivity factor that results in huge economic losses in the success of livestock production in Ethiopia. However, there is no robust information on its rate and its predictors in the mixed crop livestock production system as most studies are targeted to intensive dairy farms. A longitudinal study design was conducted from December 2018 to April 2019 in Siyadeber and Wayu districts of Amhara region, Ethiopia. A total of 135 apparently healthy calves were enrolled from randomly selected fifty-fifty households in three Kebeles of the district, namely, Gash-amba, Siyadeber, and Wale-deneba. A pretested structured questionnaire was used to collect data about the potential risk factors upon the face-to-face interview made with the owners. Calves were monitored for the incidence of morbidity in a weekly visit basis, and any clinical abnormalities were recorded on registries. The chi-square and Fisher’s exact test followed by Generalized Linear Models for binomial family extensions for risk estimate were run, and a p value <0.05 was considered statistically significant. In this study, the overall incidence rate of calf morbidity among under six months of age was 388 calves per 100,000 days of follow-up, with a cumulative incidence of 34.1% (95% CI: 26.1–42.7). Calf diarrhea, pneumonia, septicemia, dehydration, and navel ill were the encountered health problems consecutively. Among the potential risk factors, calves from Siyadeber Kebele (RR = 2.11, 95% CI: 1.13–3.94), calves housed with other livestock (RR = 2.05, 95% CI: 1.10–3.80), housed with their dam (RR = 1.92, 95% CI: 1.20–3.05), without bedding (RR = 1.89, 95% CI: 1.20–2.94), and calves whose dam age ranges from 5 to 8 years (RR = 1.87, 95% CI: 1.05–3.35) were found to be predictors of calf morbidity. In general, the high calf morbidity rates established in this study together with the alarming predictors of calf morbidity entail attention by the concerning bodies on proper management and improved health care so as to reduce the calf morbidity.

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2791. Burden of Respiratory Infections in Trainees Higher Than Healthcare Records Indicate: Results from an Anonymous Survey

Open Forum Infectious Diseases ◽

10.1093/ofid/ofz360.2468 ◽

2019 ◽

Vol 6 (Supplement_2) ◽

pp. S986-S986

Author(s):

Stephanie Richard ◽

Patrick Danaher ◽

Brian White ◽

Katrin Mende ◽

Timothy Burgess ◽

...

Keyword(s):

Risk Factors ◽

Potential Risk ◽

Respiratory Infections ◽

Smoking Status ◽

Activity Level ◽

Mitigation Strategies ◽

Military Population ◽

Chi Square ◽

Potential Risk Factors ◽

The Impact

Abstract Background Influenza-like illnesses (ILIs) are common in military populations, particularly among trainees, and can impair mission-readiness. To develop effective preventive measures against ILIs, it is vital to understand the ILI burden in the military population and identify potential risk factors for infection. Methods Anonymous ILI surveys were administered from January 2017 to March 2019 to military medical trainees living in a congregated setting on Fort Sam Houston (JBSA-FSH), TX. The surveys included questions about sociodemographic characteristics, weight, height, smoking status, activity level, as well as some basic questions about ILI and potential risk factors. Factors associated with ILI were identified using chi-square, t-tests, and multivariate models. Results 2,381 surveys were returned that included age, sex, and ILI information. Respondents were 16–54 years old, 1,301 (55%) were male, 782 (33%) were Air Force, 817 (34%) were Army, and 763 (32%) were Navy/Marines. 39% of those surveyed (929) reported having experienced an ILI during their training with 40% (370) seeking healthcare for those symptoms. The primary reasons for seeking healthcare included the severity of the illness (59%), concern about spreading the illness (50%), and the accessibility of healthcare (41%). 53% of the respondents reported that ILI had an impact on their performance, among whom 77% stated reduced study time, 66% missing physical training, and 53% missed class. The final multivariate model indicates that men and participants 30+ years old were less likely to report ILI (OR 0.69 (0.58, 0.82); OR 0.65, (0.45, 0.94)) (Figure 1). In addition, participants who reported washing their hands after they coughed or sneezed were less likely to report having had an ILI (OR 0.73 (0.61, 0.89)). Conclusion Although 39% of respondents reported having an ILI during their training, only 40% sought healthcare, indicating that ILIs are more common during training than healthcare records indicate. More information is needed regarding how training outcomes vary among those with ILI who seek care, those with ILI who do not seek care and those without ILI during training, to allow a better estimate of the impact of ILI and development of ILI mitigation strategies. Disclosures All authors: No reported disclosures.

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Hubungan Kejadian Pneumonia Neonatus dengan Beberapa Faktor Risiko di RSUP Dr. M. Djamil Padang Periode 2010-2012

Jurnal Kesehatan Andalas ◽

10.25077/jka.v5i3.585 ◽

2016 ◽

Vol 5 (3) ◽

Author(s):

Rizki Meizikri ◽

Finny Fitry Yani ◽

Yusrawati Yusrawati

Keyword(s):

Risk Factors ◽

Preterm Birth ◽

Distress Syndrome ◽

Bivariate Analysis ◽

Premature Rupture Of Membranes ◽

Chi Square ◽

Cross Sectional ◽

Cross Sectional Design ◽

Mortality Causes ◽

Research Criteria

AbstrakPneumonia merupakan salah satu penyebab mortalitas utama pada neonatus. Bayi Berat Lahir Rendah (BBLR), kelahiran preterm, ketuban pecah dini (KPD), dan demam intrapartum merupakan faktor risiko yang dapat berpengaruh terhadap kejadian pneumonia neonatus. Tujuan penelitian ini adalah menentukan hubungan antara faktor risiko tersebut dengan kejadian pneumonia neonatus di RSUP M. Djamil. Penelitian ini bersifat analitik dengan desain cross-sectional dengan mengumpulkan data rekam medis pneumonia neonatus di RSUP M. Djamil Padang periode 2010 – 2012. Kontrol diambil data neonatus yang dirawat dengan diagnosis selain pneumonia pada periode yang sama. Neonatus dengan diagnosis sindrom gawat nafas, sepsis, meningitis, asfiksia, dan aspirasi telah dieksklusi terlebih dahulu. Sejumlah 49 sampel yang memenuhi kriteria terdapat temuan; KPD sebanyak 22,4%, demam intrapartum 20,4%, BBLR 18,4%, dan kelahiran preterm 10,2%. Sebanyak 24 sampel tidak memiliki faktor risiko. Analisis bivariat chi-square menunjukkan bahwa BBLR (p=0,46), kelahiran preterm (p=0,372), KPD (p=0,616), dan demam intrapartum (p=0,083) tidak memiliki hubungan yang signifikan dengan kejadian pneumonia neonatus di RSUP M. Djamil periode 2010-2012.Kata kunci: pneumonia neonatus, BBLR, kelahiran preterm, KPD, demam intrapartum. AbstractPneumonia is one of leading mortality causes among neonates. Low Birth Weight (LBW), preterm birth, Premature Rupture Of Membranes (PROM) and intrapartum maternal fever are known as risk factors that might contribute to neonatal pneumonia occurence. The objective of this study was to determine relationship the risk factors to neonatal pneumonia in M. Djamil hospital. This analytic research with cross-sectional design compiled neonatal pneumonia data from 2010-2012 medical record M. Djamil hospital. Controls were taken from neonates hospitalized in M. Djamil within the same period. Neonates with respiratory distress syndrome, sepsis, meningitis, asphyxia, and aspiration were excluded. The 49 subjects that meet research criteria, PROM were found in 22,4% of neonates,intrapartum fever 20,4%, LBW 18,4%, and preterm birth 10,2%. Twenty four of them do not have any of those risk factors. Bivariate analysis with chi-square shows that none of those risk factors are significantly related to neonatal pneumonia in M. Djamil hospital period 2010-2012 (LBW p=0,46; preterm birth p=0,372; PROM p=0,616; intrapartum fever p=0,083).Keywords: neonatal pneumonia, LBW, preterm birth, PROM, intrapartum fever

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Perinatal Outcomes and Risk Factors for Preterm Birth in Twin Pregnancies in a Chinese Population: A Multi-center Retrospective Study

Frontiers in Medicine ◽

10.3389/fmed.2021.657862 ◽

2021 ◽

Vol 8 ◽

Author(s):

Sijian Li ◽

Jinsong Gao ◽

Juntao Liu ◽

Jing Hu ◽

Xiaoxu Chen ◽

...

Keyword(s):

Risk Factors ◽

Logistic Regression ◽

Retrospective Study ◽

Preterm Birth ◽

Potential Risk ◽

Chinese Population ◽

Neonatal Outcomes ◽

Potential Risk Factors ◽

Maternal And Neonatal Outcomes ◽

Twin Pregnancies

Background: Twin pregnancies are associated with an increased risk of adverse maternal and neonatal outcomes, mainly owing to prematurity. Few studies have evaluated the risk factors for preterm birth (PTB) in Chinese population. The objective of this study is to present the short-term maternal-neonatal outcomes, investigating the potential risk factors associated with preterm birth in Chinese twin pregnancies.Methods: A multi-center retrospective study of women pregnant with twins ≥28 weeks of gestation was conducted. Maternal and neonatal outcomes were analyzed. Logistic regression was used to identify potential risk factors for PTB before 37, 34, and 32 weeks, respectively.Results: A total of 3,288 twin pregnancies and 6,576 neonates were included in 99,585 pregnancies. The rate of twin pregnancy was 3.3%, while the PTB rate before 37, 34, and 32 weeks among this population were 62.1, 18.8, and 10.4%, respectively. Logistic regression revealed that monochorionicity [Odds ratio (OR) 3.028, 95% confident interval (CI) 2.489–3.683, P < 0.001], gestational weight gain (GWG) <10 kg (OR 2.285, 95% CI 1.563–3.339, P < 0.001) and GWG between 10 and 15 kg (OR 1.478, 95% CI 1.188–1.839, P < 0.001), preeclampsia (PE) (OR 3.067, 95% CI 2.142–4.390, P < 0.001), and intrahepatic cholestasis of pregnancy (ICP) (OR 3.122, 95% CI 2.121–4.596, P < 0.001) were the risk factors for PTB before 37 weeks. Monochorionicity (OR 2.865, 95% CI 2.344–3.501, P < 0.001), age < 25 years (OR 1.888, 95% CI 1.307–2.728, P = 0.001), and GWG <10 kg (OR 3.100, 95% CI 2.198–4.372, P < 0.001) were risk factors for PTB before 34 weeks. Monochorionicity (OR 2.566, 95% CI 1.991–3.307, P < 0.001), age younger than 25 years (OR 1.964, 95% CI 1.265–3.048, P = 0.003), and GWG <10 kg (OR 4.319, 95% CI 2.931–6.364, P < 0.001) were the risk factors for PTB before 32 weeks.Conclusions: Monochorionicity and GWG <10 kg were two major risk factors for PTB before 32, 34, and 37 weeks, whereas maternal age, PE, and ICP were also risk factors for PTB in specific gestational age.

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Prevalence of human cystic echinococcosis in the towns of Ñorquinco and Ramos Mexia in Rio Negro Province, Argentina, and direct risk factors for infection

Parasites & Vectors ◽

10.1186/s13071-021-04753-y ◽

2021 ◽

Vol 14 (1) ◽

Author(s):

Leonardo Uchiumi ◽

Guillermo Mujica ◽

Daniel Araya ◽

Juan Carlos Salvitti ◽

Mariano Sobrino ◽

...

Keyword(s):

Risk Factors ◽

Potential Risk ◽

Rural Areas ◽

Cystic Echinococcosis ◽

Significant Risk ◽

Prevalence Ratio ◽

Bivariate Analysis ◽

Rio Negro ◽

Potential Risk Factors ◽

Current Address

Abstract Background Cystic echinococcosis (CE) is a parasitic zoonosis caused by infection with the larval stage of Echinococcus granulosus (s.l.). This study investigated the prevalence and potential risk factors associated with human CE in the towns and rural areas of Ñorquinco and Ramos Mexia, Rio Negro province, Argentina. Methods To detect abdominal CE cysts, we screened 892 volunteers by ultrasound and investigated potential risk factors for CE using a standardized questionnaire. Prevalence ratio (PR) with 95% confidence intervals (CI) was used to measure the association between CE and the factors investigated, applying bivariate and multivariate analyses. Results Abdominal CE was detected in 42/892 screened volunteers (4.7%, 95% CI 3.2–6.1), only two of whom were under 15 years of age. Thirteen (30.9%) CE cases had 25 cysts in active stages (CE1, CE2, CE3a, according to the WHO Informal Working Group on Echinococcosis [WHO-IWGE] classification). The most relevant risk factors identified in the bivariate analysis included: living in rural areas (P = 0.003), age > 40 years (P = 0.000), always drinking water from natural sources (P = 0.007), residing in rural areas during the first 5 years of life (P = 0.000) and having lived more than 20 years at the current address (P = 0.013). In the multivariate final model, the statistically significant risk factors were: frequently touching dogs (P = 0.012), residing in rural areas during the first 5 years of life (P = 0.004), smoking (P = 0.000), age > 60 years (P = 0.002) and living in rural areas (P = 0.017). Conclusions Our results point toward infection with CE being acquired since childhood and with constant exposure throughout life, especially in rural areas with a general environmental contamination. Graphic Abstract

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Premature Arterial Disease Associated with Familial Antithrombin III Deficiency

Thrombosis and Haemostasis ◽

10.1055/s-0038-1645677 ◽

1990 ◽

Vol 63 (01) ◽

pp. 013-015 ◽

Cited By ~ 15

Author(s):

E J Johnson ◽

C R M Prentice ◽

L A Parapia

Keyword(s):

Risk Factors ◽

Venous Thromboembolism ◽

Potential Risk ◽

Antithrombin Iii ◽

Arterial Disease ◽

Coagulation System ◽

Early Age ◽

Arterial Thromboembolism ◽

Potential Risk Factors ◽

Antithrombin Iii Deficiency

SummaryAntithrombin III (ATIII) deficiency is one of the few known abnormalities of the coagulation system known to predispose to venous thromboembolism but its relation to arterial disease is not established. We describe two related patients with this disorder, both of whom suffered arterial thrombotic events, at an early age. Both patients had other potential risk factors, though these would normally be considered unlikely to lead to such catastrophic events at such an age. Thrombosis due to ATIII deficiency is potentially preventable, and this diagnosis should be sought more frequently in patients with arterial thromboembolism, particularly if occurring at a young age. In addition, in patients with known ATIII deficiency, other risk factors for arterial disease should be eliminated, if possible. In particular, these patients should be counselled against smoking.

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