scholarly journals Strabismus surgery in Angelman syndrome: More than ocular alignment

PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0242366
Author(s):  
Paola Michieletto ◽  
Stefano Pensiero ◽  
Laura Diplotti ◽  
Luca Ronfani ◽  
Manuela Giangreco ◽  
...  

Purpose To report and evaluate strabismus surgery in children with Angelman syndrome, in order to optimize and standardize surgical approach. Other purposes are to understand the possible relation between ocular findings and motor ability, and between improvement in ocular alignment and changes in motor skills in this population. Design Observational cross-sectional study. Methods Medical records of pediatric patients with Angelman syndrome, who underwent strabismus surgery, were investigated. Collected data included: genotype, gender, age at the time of surgery, refractive error, pre-operative strabismus, surgical procedure, surgical outcome, gross and fine motor development assessment pre- and post-operatively. Results Seventeen subjects, aged 3–15 years, were investigated. Fourteen patients were exotropic, three esotropic. Most patients presented astigmatism. Considering the exaggerated response to standard amounts of surgery and the risk of consecutive strabismus on long term follow-up reported by previous studies in children with developmental delay, a reduction of the amount of strabismus surgery was applied. Post-operatively, all patients presented with a significative reduction of the baseline deviation angle, with all esotropic patients and 7 exotropic patients (59%) achieving orthotropia. The surgical outcomes were variable according to the type and the amount of baseline strabismus, but no case presented with exaggerated surgical response. At baseline, patients showed important delays in all motor abilities, and, post-operatively, presented a significant improvement in walking and fine motor tasks. Pre- and post-operative motor abilities were negatively correlated to astigmatism, anisometropia, and amount of deviation. Conclusions According to our data, the standard nomograms for strabismus surgery may be successfully applied in subjects with Angelman syndrome and exotropia. Our data suggest that the reduction of the deviation angle improves motor skills in strabismic pediatric patients with Angelman syndrome.

2021 ◽  
pp. 003151252110131
Author(s):  
Clarice Maria de Lucena Martins ◽  
Cain Craig Truman Clark ◽  
Rafael Miranda Tassitano ◽  
Anastácio Neco de Souza Filho ◽  
Anelise Reis Gaya ◽  
...  

Little is known of how reallocations of time spent in different movement behaviors during preschool might relate to preschoolers’ fundamental movement skills (FMS), a key predictor of later physical activity (PA). Thus, the aim of this study was to examine (a) whether preschoolers’ school-time movement was associated with their FMS and (b) the effects on FMS of reallocating time between PA and sedentary behavior (SB). This was a cross-sectional study, using intervention data with Brazilian low-income preschoolers. We observed Brazilian preschoolers of both sexes ( Mage = 4.5, SD = 0.8 years-old; 101boys) over 10 hours of school-time and objectively assessed their PA and SB with Actigraph wGT3X and their FMS with the Test of Gross Motor Development – Second Edition. We explored the associations between school-time movement behaviors and FMS and between reallocated school-time movement behaviors and FES using compositional analysis in R (version 1.40-1), robCompositions (version 0.92-7), and lmtest (version 0.9-35) packages. This isotemporal reallocation showed that, for manipulative skills, reallocating time (5, 10, and 15 minutes, respectively) from light PA to SB was associated with increasing skill (0.14, 0.28, and 0.42 FMS units), raising questions as to whether fine motor activity occurred during SB. Thus, school-time movement significantly predicted FMS, with a modest increase in SB, at the expense of light PA eliciting improved manipulative skills.


2021 ◽  
Vol 18 (3) ◽  
pp. 318-324
Author(s):  
Elnaz Emadirad ◽  
Brad W.N. Temple ◽  
Stephanie C. Field ◽  
Patti-Jean Naylor ◽  
Viviene A. Temple

Background: Beyond the often examined perceptions of competence and motor skill proficiency, perceived value and children’s expectations for success are thought to affect engagement in physical activities. We used parallel mediation models to examine the direct effect of motor skill proficiency on participation in physical activities, as well as whether children’s beliefs and value for physical activities mediated this relationship. Methods: The participants in this cross-sectional study were a total of 398 grade 3 children (201 girls) from 8 schools. Motor skills were assessed using the Test of Gross Motor Development-2, the Value Expectancy Questionnaire measured the psychological variables, and the Children’s Assessment of Participation and Enjoyment measured physical activities. Results: Motor skill proficiency predicted all 3 psychological constructs for the boys and the girls, and boys’ participation in physical activities. However, the psychological variables did not mediate the relationship between motor skills and participation among the boys. For the girls, task value mediated the relationship between motor skills and physical activity participation. Conclusion: It is possible that the girls are further along in their ability to reflect on their competence, successes, and failures; it is also possible that the lower motor skill levels of girls had a deleterious effect on their feelings about participating.


2022 ◽  
Vol 13 (1) ◽  
pp. 019-026
Author(s):  
Silé Souam Nguélé ◽  
Haoua Démadji Béléti ◽  
Djidita Hagré Youssouf ◽  
Kanezouné Gongnet ◽  
Ildjima Ousmane Kadallah ◽  
...  

Introduction: Psychomotor development (PMD) reflects the cerebral maturation through sensory, motor and psychological acquisitions of an individual. Its evaluation allows an early diagnosis of delays in order to take care of them. The objective of this study was to determine the profile and explanatory factors of PMD of infants in N'Djamena. Methods: This was a cross-sectional study conducted at the “Notre Dame des Apôtres” Hospital in N'Djamena. It involved 428 infants aged 1 to 24 months received in preventive consultation between October 2017 and June 2018. The Denver II scale was used for the assessment of PMD. Data were analyzed with SPSS 21.0 software. Results: the sex ratio was 1.06. The most represented age group was under 3 months (35.5%). The items of gross motor skills were 95% completed, fine motor skills 93.8%, language 84.6% and sociability 68.8% at the 90th percentile. Development was advanced in 56.8% normal in 32.1% and delayed in 2.1%. Statistically significant differences in PMD were observed according to age group (p= 0.000), vaccination status (p= 0.002), feeding mode (p= 0.000), maternal exchange (p= 0.000) and pregnancy follow-up (p= 0.03). Conclusion: The psychomotor development of N'Djamenese infants is similar to that of other African children, although some variations are noted. It is influenced by certain factors related to the infant and the mother.


2017 ◽  
Vol 27 (4) ◽  
pp. 27993 ◽  
Author(s):  
Donesca Machado ◽  
Nadia Cristina Valentini ◽  
Alessandra Bombarda Müller ◽  
Keila Ruttnig Guidony Pereira

***Motor development, cognition and language in infants who attend day care centers***   AIMS: To evaluate the acquisition of motor milestones in the first two years of life and the relationship between gross motor function and manipulation, cognition and language in infants who attend day care centers.   METHODS: Cross-sectional study with a non-probabilistic sample of infants attending public and private day care centers in a city in southern Brazil. The Alberta Infant Motor Scale and the Bayley Scales of Infant and Toddler Development were used to assess the motor performance of each child. Descriptive statistics were used for the characterization of the sample and simple linear regression in three different age groups (group 1: between six and nine months; group 2: between 10 and 12 months; group 3: between 13 and 16 months) for the analysis of relationships between the variables gross and fine motor skills, cognition and language.   RESULTS: We studied 63 infants between six and 16 months of age who did not present statistically significant differences in their biological and sociodemographic characteristics when the three stratified groups were compared. Most children did not acquire the developmental milestones in the period expected for their age group. There was correlation between the developmental scores, and the gross motor function was able to explain a large part of the variability in the fine motor function, cognition and language scores (R2ajust>0.5) over the first two years of life.   CONCLUSIONS: The evaluated motor skills occurred generally late in the sample. The delay in the acquisition of gross motor milestones had an impact on the overall developmental skills, corroborating the influence of gross motor function in the other domains of development.


1984 ◽  
Vol 64 (3) ◽  
pp. 308-316 ◽  
Author(s):  
Kathleen Noller ◽  
Dennis Ingrisano

2018 ◽  
Vol 1 (1) ◽  
pp. 6-10
Author(s):  
Gurnal Rai Gandra Siregar ◽  
Munar Lubis ◽  
Isti Ilmiati Fujiati

World Health Organization (WHO) recommends to continue breastfeeding until two years of age. There are few studies assessing the correlation between breastfeeding duration and motor development. A cross-sectional study was conducted in April 2016 in Muara Batang Gadis District. The sample were children 3-6 years of age. Breastfeeding duration was obtained by interview, and motor development was assessed using Denver Developmental Screening Test II. Chi-square test was used to evaluate the correlation between breastfeeding duration and motor development, with P-value <0.05 and 95% Confidence Interval (CI). Among 204 children, 5.4% had the fine motor delay, and 1% had the gross motor delay. Children with breastfeeding duration for at least for two years had better fine motor development compared to breastfeeding duration for less than two years (P<0.001, PR=1.139, 95% CI=1.055-1.231) and there is no difference in gross motor development (P=0.193, PR=1.023, 95% CI=0.991-1.055). There is a correlation between breastfeeding duration and fine motor development.


2020 ◽  
Vol 14 (2) ◽  
pp. 85
Author(s):  
Supratti Supratti ◽  
Iqra S

Improving the quality of Human Resources (HR) through stimulation of growth and development in children aged under two years (0-24 months), needs to be a priority concern of parents / caregivers considering this period is called the "golden age" or golden period, because brain development is very fast at two year old baby / BADUTA. Low Birth Weight (LBW) infants are at risk of growth and development disorders if LBW treatment and stimulation of development are not optimal and continuous. The research objective was to determine the development of Baduta motor skills with a history of LBW in the Regency. Descriptive research with the Cross Sectional Study approach. The study population was all Baduta with a history of LBW in Mamuju District, Mamuju District. The sample of this study was Baduta who had a history of low birth weight birth and lived in Mamuju District. the number of samples is 28 million, using the KPSP Pre Srining Development Questionnaire (KPSP) measuring gross motor development and fine motor development. The results showed that there were still 11 baduta (39.3%) unable to do gross motor skills and 5 baduta (17.9%) unable to do fine motor skills


Author(s):  
Elena Pinero-Pinto ◽  
Verónica Pérez-Cabezas ◽  
Concepción De-Hita-Cantalejo ◽  
Carmen Ruiz-Molinero ◽  
Estanislao Gutiérrez-Sánchez ◽  
...  

Many studies have established a relationship between visual function and motor development in toddlers. This is the first report to study two-year-olds via an assessment of their visual and motor skills. The purpose of this study is to describe the possible changes that can occur between visual and motor systems in typical developing toddlers. A total of 116 toddlers were included in this observational, descriptive, and cross-sectional study. Their mean age was 29.57 ± 3.45 months. Motor development variables studied were dominant hand/foot; stationary, locomotion, object manipulation, grasping, visual motor integration percentiles; gross motor, fine motor, and total motor percentiles; and gross motor, fine motor, and total motor quotients. Visual development variables were assessed including visual acuity, refractive error, ocular alignment, motor fusion and suppression, ocular motility, and stereopsis. Our findings demonstrated that typical developing toddlers with slow gross motor development had higher exophoria and further near point of convergence values compared to toddlers with fast gross motor development (p < 0.05). No statistically significant differences were found in visual acuity and stereopsis between slow and fast gross motor development toddlers.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Amirhossein Hosseini ◽  
Anahita Fayaz ◽  
Hossein Hassanian-Moghaddam ◽  
Nasim Zamani ◽  
Seyed Kaveh Hadeiy ◽  
...  

Abstract Background Lead exposure is one of the most menacing of environmental exposures, particularly in children. Children are more susceptible to the effects of lead which manifest in many organ systems, including interference with mental and motor development. Lead poisoning can cause colicky abdominal pain. In this study, the authors sought to evaluate the prevalence of elevated blood lead level (BLL) and its contributing factors among pediatric patients presenting with abdominal pain. An epidemic of lead poisoning in adults was previously uncovered, and thus a concern for pediatric lead poisoning was raised. Methods Pediatric patients presenting to two pediatric clinics in Tehran with abdominal pain were eligible for enrollment in a descriptive prospective cross-sectional study. A predesigned questionnaire was filled for each patient by their consenting parents. The questionnaire queried demographic information, environmental, social, and other relevant parameters for lead exposure. After completion of the questionnaire, biometrics were obtained, and a blood sample was taken from each patient for measurement of BLL and complete blood count. Results A total of 187 patients were enrolled in the study. Of them, almost 20% had BLL ≥ 5 µg/dL. Univariate analysis showed that age (p = 0.002, OR 3.194, CI 95% 1.504–6.783), weight (p = 0.009, OR 2.817, CI 95% 1.266–6.269), height (p = 0.003, OR 3.155, CI 95% 1.443–6.899), and playing with both plastic and cotton toys (p = 0.03, OR 2.796, CI 95% 1.072–7.295) were significant predictors of high BLLs. Maternal level of education correlated with blood lead concentrations (p = 0.048, OR 2.524, CI 95% 1.006–6.331). Conclusions A clinically significant number of cases of abdominal pain may have high BLLs. Specific attention should be paid to children presenting with abdominal pain, especially due to the detrimental effects of lead on their mental and motor development.


2022 ◽  
Author(s):  
Venera Gashaj ◽  
Dragan Trninic

We explore the relationship between mathematical skills and motor skills across three age groups of normally developing children. The existence of such a relationship is postulated in classical accounts of human development. In contemporary research, the existence of a relationship between motor development and the development of abstract concepts may form a crucial piece of evidence for theories of embodied cognition. Existing studies suggest a link between fine motor skills and various numerical and mathematical tasks in young children; however, there are few attempts to measure the strength of this relationship across different ages. We use a cross-sectional design to investigate the link between fine motor and mathematical skills in children in Kindergarten, 2nd grade, and 4th grade. The results show that correlational patterns vary in the three ages; while in Kindergarten manual dexterity of the dominant hand is related to math skills, in 2nd grade the manual dexterity of the nondominant hand is related to math skills, and finally, in 4th grade no such correlations are observable.


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