scholarly journals DAVS-NET: Dense Aggregation Vessel Segmentation Network for retinal vasculature detection in fundus images

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0261698
Author(s):  
Mohsin Raza ◽  
Khuram Naveed ◽  
Awais Akram ◽  
Nema Salem ◽  
Amir Afaq ◽  
...  
Keyword(s):  
Deep Learning ◽  
Blood Vessels ◽  
Medical Image Analysis ◽  
Retinal Disease ◽  
Disease Diagnosis ◽  
Vessel Segmentation ◽  
Diabetic Patients ◽  
Retinal Vasculature ◽  
Retinal Blood Vessels ◽  
Dense Aggregation

In this era, deep learning-based medical image analysis has become a reliable source in assisting medical practitioners for various retinal disease diagnosis like hypertension, diabetic retinopathy (DR), arteriosclerosis glaucoma, and macular edema etc. Among these retinal diseases, DR can lead to vision detachment in diabetic patients which cause swelling of these retinal blood vessels or even can create new vessels. This creation or the new vessels and swelling can be analyzed as biomarker for screening and analysis of DR. Deep learning-based semantic segmentation of these vessels can be an effective tool to detect changes in retinal vasculature for diagnostic purposes. This segmentation task becomes challenging because of the low-quality retinal images with different image acquisition conditions, and intensity variations. Existing retinal blood vessels segmentation methods require a large number of trainable parameters for training of their networks. This paper introduces a novel Dense Aggregation Vessel Segmentation Network (DAVS-Net), which can achieve high segmentation performance with only a few trainable parameters. For faster convergence, this network uses an encoder-decoder framework in which edge information is transferred from the first layers of the encoder to the last layer of the decoder. Performance of the proposed network is evaluated on publicly available retinal blood vessels datasets of DRIVE, CHASE_DB1, and STARE. Proposed method achieved state-of-the-art segmentation accuracy using a few number of trainable parameters.

scholarly journals Impact of Novel Image Preprocessing Techniques on Retinal Vessel Segmentation

Electronics ◽  
2021 ◽  
Vol 10 (18) ◽  
pp. 2297
Author(s):  
Toufique A. Soomro ◽  
Ahmed Ali ◽  
Nisar Ahmed Jandan ◽  
Ahmed J. Afifi ◽  
Muhammad Irfan ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Retinal Disease ◽  
Retinal Vessel ◽  
Vessel Segmentation ◽  
Low Contrast ◽  
The Public ◽  
Retinal Blood Vessels ◽  
Retinal Vessel Segmentation ◽  
Automated Screening ◽  
Traditional Image

Segmentation of retinal vessels plays a crucial role in detecting many eye diseases, and its reliable computerized implementation is becoming essential for automated retinal disease screening systems. A large number of retinal vessel segmentation algorithms are available, but these methods improve accuracy levels. Their sensitivity remains low due to the lack of proper segmentation of low contrast vessels, and this low contrast requires more attention in this segmentation process. In this paper, we have proposed new preprocessing steps for the precise extraction of retinal blood vessels. These proposed preprocessing steps are also tested on other existing algorithms to observe their impact. There are two steps to our suggested module for segmenting retinal blood vessels. The first step involves implementing and validating the preprocessing module. The second step applies these preprocessing stages to our proposed binarization steps to extract retinal blood vessels. The proposed preprocessing phase uses the traditional image-processing method to provide a much-improved segmented vessel image. Our binarization steps contained the image coherence technique for the retinal blood vessels. The proposed method gives good performance on a database accessible to the public named DRIVE and STARE. The novelty of this proposed method is that it is an unsupervised method and offers an accuracy of around 96% and sensitivity of 81% while outperforming existing approaches. Due to new tactics at each step of the proposed process, this blood vessel segmentation application is suitable for computer analysis of retinal images, such as automated screening for the early diagnosis of eye disease.

scholarly journals Retinal blood vessel segmentation using a deep learning method based on modified U-NET model

2021 ◽  
Author(s):  
Sanjeewani NA ◽  
arun kumar yadav ◽  
Mohd Akbar ◽  
mohit kumar ◽  
Divakar Yadav
Keyword(s):  
Deep Learning ◽  
Blood Vessel ◽  
Blood Vessels ◽  
Automatic Segmentation ◽  
Vessel Segmentation ◽  
Great Success ◽  
Retinal Blood Vessel ◽  
Data Set ◽  
Blood Vessel Segmentation ◽  
Retinal Blood Vessels

<div>Automatic retinal blood vessel segmentation is very crucial to ophthalmology. It plays a vital role in the early detection of several retinal diseases such as Diabetic Retinopathy, hypertension, etc. In recent times, deep learning based methods have attained great success in automatic segmentation of retinal blood vessels from images. In this paper, a U-NET based architecture is proposed to segment the retinal blood vessels from fundus images of the eye. Furthermore, 3 pre-processing algorithms are also proposed to enhance the performance of the system. The proposed architecture has provided significant results. On the basis of experimental evaluation on the publicly available DRIVE data set, it has been observed that the average accuracy (Acc) is .9577, sensitivity (Se) is .7436, specificity (Sp) is .9838 and F1-score is .7931. The proposed system outperforms all recent state of art approaches mentioned in the literature.</div>

scholarly journals Retinal blood vessel segmentation using a deep learning method based on modified U-NET model

2021 ◽  
Author(s):  
Sanjeewani NA ◽  
arun kumar yadav ◽  
Mohd Akbar ◽  
mohit kumar ◽  
Divakar Yadav
Keyword(s):  
Deep Learning ◽  
Blood Vessel ◽  
Blood Vessels ◽  
Automatic Segmentation ◽  
Vessel Segmentation ◽  
Great Success ◽  
Retinal Blood Vessel ◽  
Data Set ◽  
Blood Vessel Segmentation ◽  
Retinal Blood Vessels

<div>Automatic retinal blood vessel segmentation is very crucial to ophthalmology. It plays a vital role in the early detection of several retinal diseases such as Diabetic Retinopathy, hypertension, etc. In recent times, deep learning based methods have attained great success in automatic segmentation of retinal blood vessels from images. In this paper, a U-NET based architecture is proposed to segment the retinal blood vessels from fundus images of the eye. Furthermore, 3 pre-processing algorithms are also proposed to enhance the performance of the system. The proposed architecture has provided significant results. On the basis of experimental evaluation on the publicly available DRIVE data set, it has been observed that the average accuracy (Acc) is .9577, sensitivity (Se) is .7436, specificity (Sp) is .9838 and F1-score is .7931. The proposed system outperforms all recent state of art approaches mentioned in the literature.</div>

scholarly journals HDC-Net: A hierarchical dilation convolutional network for retinal vessel segmentation

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257013
Author(s):  
Xiaolong Hu ◽  
Liejun Wang ◽  
Shuli Cheng ◽  
Yongming Li
Keyword(s):  
Deep Learning ◽  
Blood Vessels ◽  
Structural Information ◽  
Retinal Vessel ◽  
Vessel Segmentation ◽  
Convolutional Network ◽  
Retinal Blood Vessels ◽  
Retinal Vessel Segmentation ◽  
Ophthalmic Diseases ◽  
Sensitivity Specificity

The cardinal symptoms of some ophthalmic diseases observed through exceptional retinal blood vessels, such as retinal vein occlusion, diabetic retinopathy, etc. The advanced deep learning models used to obtain morphological and structural information of blood vessels automatically are conducive to the early treatment and initiative prevention of ophthalmic diseases. In our work, we propose a hierarchical dilation convolutional network (HDC-Net) to extract retinal vessels in a pixel-to-pixel manner. It utilizes the hierarchical dilation convolution (HDC) module to capture the fragile retinal blood vessels usually neglected by other methods. An improved residual dual efficient channel attention (RDECA) module can infer more delicate channel information to reinforce the discriminative capability of the model. The structured Dropblock can help our HDC-Net model to solve the network overfitting effectively. From a holistic perspective, the segmentation results obtained by HDC-Net are superior to other deep learning methods on three acknowledged datasets (DRIVE, CHASE-DB1, STARE), the sensitivity, specificity, accuracy, f1-score and AUC score are {0.8252, 0.9829, 0.9692, 0.8239, 0.9871}, {0.8227, 0.9853, 0.9745, 0.8113, 0.9884}, and {0.8369, 0.9866, 0.9751, 0.8385, 0.9913}, respectively. It surpasses most other advanced retinal vessel segmentation models. Qualitative and quantitative analysis demonstrates that HDC-Net can fulfill the task of retinal vessel segmentation efficiently and accurately.

scholarly journals Deep Convolution Neural Networks for Medical Image Analysis

2018 ◽  
Vol 7 (3.33) ◽  
pp. 115 ◽  
Author(s):  
Myung Jae Lim ◽  
Da Eun Kim ◽  
Dong Kun Chung ◽  
Hoon Lim ◽  
Young Man Kwon
Keyword(s):  
Breast Cancer ◽  
Deep Learning ◽  
Early Detection ◽  
Medical Image ◽  
Medical Images ◽  
Medical Image Analysis ◽  
Disease Diagnosis ◽  
Learning Approach ◽  
Histopathological Image ◽  
Approach Method

Breast cancer is a highly contagious disease that has killed many people all over the world. It can be fully recovered from early detection. To enable the early detection of the breast cancer, it is very important to classify accurately whether it is breast cancer or not. Recently, the deep learning approach method on the medical images such as these histopathologic images of the breast cancer is showing higher level of accuracy and efficiency compared to the conventional methods. In this paper, the breast cancer histopathological image that is difficult to be distinguished was analyzed visually. And among the deep learning algorithms, the CNN(Convolutional Neural Network) specialized for the image was used to perform comparative analysis on whether it is breast cancer or not. Among the CNN algorithms, VGG16 and InceptionV3 were used, and transfer learning was used for the effective application of these algorithms.The data used in this paper is breast cancer histopathological image dataset classifying the benign and malignant of BreakHis. In the 2-class classification task, InceptionV3 achieved 98% accuracy. It is expected that this deep learning approach method will support the development of disease diagnosis through medical images.  

scholarly journals Deep Learning Models for Retinal Blood Vessels Segmentation: A Review

IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 71696-71717 ◽  
Author(s):  
Toufique Ahmed Soomro ◽  
Ahmed J. Afifi ◽  
Lihong Zheng ◽  
Shafiullah Soomro ◽  
Junbin Gao ◽  
...  
Keyword(s):  
Deep Learning ◽  
Blood Vessels ◽  
Learning Models ◽  
Retinal Blood Vessels

scholarly journals Segmenting Retinal Blood Vessels with Gabor Filter and Automatic Binarization

2018 ◽  
Vol 7 (4.11) ◽  
pp. 163 ◽  
Author(s):  
Aziah Ali ◽  
Aini Hussain ◽  
Wan Mimi Diyana Wan Zaki
Keyword(s):  
Blood Vessels ◽  
Gabor Filter ◽  
Retinal Disease ◽  
Gabor Wavelet ◽  
Fundus Image ◽  
Small Blood Vessel ◽  
Binary Images ◽  
Filter Output ◽  
Retinal Blood Vessels ◽  
Otsu’S Method

For timely diagnosis of retinal disease, routine retinal monitoring of people with high risk should be put in place. To assist the ophthalmologists in performing retinal analysis efficiently and accurately, numerous studies have been conducted to propose an automated retinal diagnosis system. One of the crucial steps for such a system is accurate detection of retinal blood vessels from retinal image. In this paper, we investigated the use of automatic binarization methods on pre-processed fundus image to detect retinal blood vessels. Three methods for binarization were investigated in this study, namely Otsu’s method, ISODATA and K-means clustering method. The resulting binarized output indicated good detection of large vessels but most of the smaller vessels were left undetected. To address this issue, Gabor wavelet filter was used to enhance the small blood vessel structures before binarization of the filter output. Combining the binary images from both binarization with and without Gabor filter resulted in significant improvement of the overall detection rate of the retinal blood vessels. The proposed method proved to be comparable to other unsupervised techniques in the literature when validated using the publicly available fundus image database, DRIVE.  

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