scholarly journals Synthesis of Nanofiber from Polyvinyl Alcohol (PVA)-Collagen Using Electrospinning Methods

2020 ◽  
Vol 21 (2) ◽  
pp. 55-65
Author(s):  
Sudirman Sudirman ◽  
Aloma Karo Karo ◽  
Sulistiyoso Giat Sukaryo ◽  
Karina Dwi Adistiana ◽  
Kiagus Dahlan
Keyword(s):  
Mechanical Properties ◽  
Polyvinyl Alcohol ◽  
Aqueous Solutions ◽  
Functional Groups ◽  
Wound Dressing ◽  
Collagen Fiber ◽  
Tissue Formation ◽  
Collagen Concentration ◽  
Electrospinning Method ◽  
Growth Of Bacteria

Polyvinil alcohol (PVA) polymer can be used as matrix to be mixed with collagen in the subtance of primary wound dressing material to cover wound that prevents growth of bacteria and enhanced tissue formation. Collagen fiber is fragile, so important to combined with PVA to obtain better mechanical properties. The PVA-collagen fibers are prepared in aqueous solutions with PVA (10%) and collagen concentration (1% and 2%) using electrospinning method and the effect of voltage 15 kV, 19 kV, and 23 kV. Analysis of functional groups show that the presence of identical compounds produced and new functional groups are not formed. SEM data show that the effect of variation of voltage and collagen concentration on the resulting morphology of fiber. PVA-collagen 2% fibers produce continuous fibers, has a diameter 284-426 nm, thickness 0.0324-0.0483 mm and has a high percent of elongation so it can be used as a wound dressing material.

scholarly journals RHEOLOGY OF WATER-SOLUBLE MONOMERS AND THEIR MIXTURES

2021 ◽  
pp. 113-122
Author(s):  
Межлум Левонович Ерицян ◽  
Армен Мамиконович Арустамян ◽  
Валентина Межлумовна Мависакалян
Keyword(s):  
Acrylic Acid ◽  
Spatial Structure ◽  
Polyvinyl Alcohol ◽  
Aqueous Solutions ◽  
Functional Groups ◽  
Polyacrylic Acid ◽  
Relative Viscosity ◽  
Water Soluble ◽  
Simultaneous Formation

Исследована реология водных растворов полиакриловой кислоты, полиакриламида, поливинилового спирта, сополимера акриловой кислоты с акриламидом, a также смесeй водных растворов этих полимеров. В результате образования ассоциатов между функциональными группами уаказанных полимеров значительно повышается относительная вязкость их водных растворов. Установлено, что при температуре 95C в водных растворах полиакриламида и сополимера акриловой кислоты с акриламидом происходит интенсивное выделение аммиака с одновременным образованием полимера пространственной структуры. The rheology of aqueous solutions of polyacrylic acid, polyacrylamide, polyvinyl alcohol, copolymer of acrylic acid with acrylamide, as well as mixtures of aqueous solutions of these polymers was investigated. As a result of the formation of associates between the functional groups of the polymers indicated, the relative viscosity of their aqueous solutions significantly increases. It was established that at a temperature of 95°C in aqueous solutions of polyacrylamide and a copolymer of acrylic acid and acrylamide, there is an intense release of ammonia with simultaneous formation of a polymer of spatial structure.

Mechanical Properties of Graphene Oxide/Polyvinyl Alcohol Composite Film

2017 ◽  
Vol 25 (1) ◽  
pp. 11-16 ◽  
Author(s):  
Tao Cheng-an ◽  
Zhang Hao ◽  
Wang Fang ◽  
Zhu Hui ◽  
Zou Xiaorong ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Graphene Oxide ◽  
Hydrogen Bonds ◽  
Polyvinyl Alcohol ◽  
Composite Film ◽  
Functional Groups ◽  
Failure Strain ◽  
Oh Groups ◽  
Enhancement Mechanism

Graphene oxide (GO) was served as mechanical strengthening to prepare GO/Polyvinyl Alcohol(PVA) composite film. This was accomplished in order to explore the influence of contents of GO on the tensile strength and failure strain of GO/PVA composite film. The results showed that as the GO content increased, the tensile strength of the composite film became greater rapidly at first, and then decreased gradually. When the GO content was 20%, the film had its maximum tensile strength (59.6 MPa). This is over 500% of the tensile strength of pure PVA film. The failure strain of GO/PVA composite film decreased rapidly as the GO content increased. The enhancement mechanism of the composite can be explained by the existence of multi-hydrogen bonds between the hydroxyl (-OH) groups of PVA and oxygen-containing functional groups of GO.

Fabrication and characterisation of a wound dressing composed of polyvinyl alcohol and quince seed mucilage

2021 ◽  
Vol 30 (Sup9a) ◽  
pp. XIIIi-XIIIx
Author(s):  
Mahshid Jafari ◽  
Hossein Baniasadi ◽  
Alireza Rezvanpour ◽  
Marzieh Lotfi
Keyword(s):  
Polyvinyl Alcohol ◽  
Wound Dressing ◽  
Healing Process ◽  
Average Diameter ◽  
Wound Dressings ◽  
Fibroblast Cells ◽  
Sem Images ◽  
Freeze Dried ◽  
Electrospinning Method ◽  
Seed Mucilage

Objective: Providing a suitable environment to improve the healing process is the main target of wound dressing that also protects the wound from additional harms. In the present study, fabrication and characterisation of a new kind of electrospun wound dressing composed of polyvinyl alcohol (PVA) and quince seed mucilage (QSM) is reported. Method: QSM was extracted from quince seeds, purified, freeze-dried and used to produce aqueous solutions containing different amounts of PVA and QSM. The wound dressings were fabricated via the electrospinning method and their characteristics were investigated with scanning electron microscope (SEM) images, Fourier transform infrared (FTIR) spectra, tensile and swelling test, and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) cytotoxicity assay against fibroblast cells. Results: SEM images confirmed that proper, uniform, non-oriented nanofibres with an average diameter in the range of 60–240nm, depending on the QSM content had been fabricated. The tensile test showed that with increasing QSM content, the tensile strength of fibre increased while elongation at break was decreased, which was consistent with SEM images where the diameter of samples decreased by increasing QSM content. MTT assay showed significant biocompatibility against fibroblast cells; however, it was increased by increased QSM proportion. In addition, SEM images supported the proper adhesion of fibroblast cells on the sample one day after culturing. Conclusion: Overall, the findings of the current study support the potential of PVA/QSM nanofibres as a proper candidate for biomedical applications, especially as a wound dressing.

Tuning the mechanical properties of cellulose nanofibrils reinforced polyvinyl alcohol composites via altering the cellulose polymorphs

RSC Advances ◽  
2016 ◽  
Vol 6 (86) ◽  
pp. 83356-83365 ◽  
Author(s):  
Xiaran Miao ◽  
Feng Tian ◽  
Jinyou Lin ◽  
Hui Li ◽  
Xiuhong Li ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Aspect Ratio ◽  
Polyvinyl Alcohol ◽  
Polymer Composites ◽  
Functional Groups ◽  
Cellulose Nanofibrils ◽  
Reinforcement Effect ◽  
Cellulose I

Cellulose nanofibrils (CNF) with polymorphs of cellulose I and II are different in morphology, aspect ratio, density of functional groups and mechanical properties, which influence the reinforcement effect for polymer composites.

Study on Medical Polyvinyl Alcohol (PVA) / Polyvinyl Pyrrolidone (PVP) Hydrogel Wound Dressing

2011 ◽  
Vol 287-290 ◽  
pp. 1925-1928
Author(s):  
Shu Di Zhang ◽  
Yu Chun Zhai ◽  
Zhen Fang Zhang
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Polyvinyl Alcohol ◽  
Water Absorption ◽  
Human Body ◽  
Wound Dressing ◽  
Ph Value ◽  
Polyvinyl Pyrrolidone ◽  
Water Contents

Polyvinyl alcohol (PVA)/polyvinyl pyrrolidone (PVP) hydrogel wound dressing has been fabricated using freezing-thawing method. The content of water, the rate of water absorption and pH value of hydrogel were tested, The mechanical properties and water transmissivities of hydrogels were analyzed when the PVP contents were difference. Experiments results show that the hydrogels diaphaneity is better, water contents are over 70percent; water transmissivity of hydrogels are over 100 percent, the highest value reaches to 204 percent; the pH value closes to the level of human body, the highest pH value reaches to 6.83; the tensile strength of hydrogel is 0.75 MPa when PVP content is 8 percent, reaches to the largest value; all of PVA/PVP hydrogels water transmissivities reach to 700 g·m-2·24h-1.

Post-Processing of Chitosan Based Nanofibers Prepared by Electrospinning

2013 ◽  
Vol 873 ◽  
pp. 652-662 ◽  
Author(s):  
Kang Sun ◽  
Yuan Xin Ge ◽  
Zhong Hui Li ◽  
Xiao Lin Zhang
Keyword(s):  
Mechanical Properties ◽  
Drug Delivery ◽  
Tissue Engineering ◽  
Aqueous Solutions ◽  
Enzyme Immobilization ◽  
Wound Dressing ◽  
Alkali Treatment ◽  
The Other ◽  
Post Processing

Recently, electrospinning of nanofibers based on chitosan has been widely studied and numerous chitosan based nanofibers have been prepared, for the enormous possibilities of applications in various areas such as filtration, enzyme immobilization, tissue engineering, wound dressing, drug delivery, and catalysis. Because most of the chitosan based nanofibers are soluble in aqueous solutions and the other properties such as mechanical properties are not suitable for the further applications. It is necessary to improve the properties of chitosan based nanofibers. Various post-processing has been done to the chitosan based nanofibers and many post-processing products have emerged. This article discusses the post-processing of the chitosan based nanofibers involving methods, mechanisms, changes of nanofiber properties, and applications of the post-processing products in details. The post-processing is divided into alkali treatment, crosslinking, and functionalizing.

scholarly journals Preparation of a Hydrogel Nanofiber Wound Dressing

Nanomaterials ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 2178
Author(s):  
Radek Jirkovec ◽  
Alzbeta Samkova ◽  
Tomas Kalous ◽  
Jiri Chaloupek ◽  
Jiri Chvojka
Keyword(s):  
Mechanical Properties ◽  
Polyvinyl Alcohol ◽  
Wound Dressing ◽  
Testing Procedure ◽  
Fibrous Layer ◽  
Skin Cover ◽  
Before And After ◽  
Strength And Ductility ◽  
Do So

The study addressed the production of a hydrogel nanofiber skin cover and included the fabrication of hydrogel nanofibers from a blend of polyvinyl alcohol and alginate. The resulting fibrous layer was then crosslinked with glutaraldehyde, and, after 4 h of crosslinking, although the gelling component, i.e., the alginate, crosslinked, the polyvinyl alcohol failed to do so. The experiment included the comparison of the strength and ductility of the layers before and after crosslinking. It was determined that the fibrous layer following crosslinking evinced enhanced mechanical properties, which acted to facilitate the handling of the material during its application. The subsequent testing procedure proved that the fibrous layer was not cytotoxic. The study further led to the production of a modified hydrogel nanofiber layer that combined polyvinyl alcohol with alginate and albumin. The investigation of the fibrous layers produced determined that following contact with water the polyvinyl alcohol dissolved leading to the release of the albumin accompanied by the swelling of the alginate and the formation of a hydrogel.

RADIATION-INDUCED DECOMPOSITION AND POLYMERIZATION OF POLYVINYL ALCOHOL IN AQUEOUS SOLUTIONS

2013 ◽  
Vol 12 (7) ◽  
pp. 1323-1328 ◽  
Author(s):  
Lujun Chen ◽  
Weihua Sun ◽  
Jinping Tian ◽  
Jianlong Wang ◽  
Shijun He
Keyword(s):  
Polyvinyl Alcohol ◽  
Aqueous Solutions ◽  
Radiation Induced ◽  
Induced Decomposition

Sorption of Lead by the Selective Ion Exchanger Ostsorb DETA

1992 ◽  
Vol 57 (7) ◽  
pp. 1393-1404 ◽  
Author(s):  
Ladislav Svoboda ◽  
Jan Uhlíř ◽  
Zdeněk Uhlíř
Keyword(s):  
Phosphoric Acid ◽  
Aqueous Solutions ◽  
Functional Groups ◽  
Ion Exchanger ◽  
Preconcentration Procedure ◽  
Bead Cellulose

The properties of Ostsorb DETA, a selective ion exchanger based on modified bead cellulose with chemically bonded diethylenetriamine functional groups, were studied, and its applicability to the preconcentration of trace amounts of lead from aqueous solutions was verified. The conditions of the preconcentration procedure in the column and batch modes were optimized for this purpose. The results obtained were applied to the determination of lead in phosphoric acid.

scholarly journals Fabrication of Hybrid Nanofibers from Biopolymers and Poly (Vinyl Alcohol)/Poly (ε-Caprolactone) for Wound Dressing Applications

Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2104
Author(s):  
Sibusiso Alven ◽  
Blessing Atim Aderibigbe
Keyword(s):  
Mechanical Properties ◽  
Wound Healing ◽  
Vinyl Alcohol ◽  
Wound Dressing ◽  
Chronic Wounds ◽  
Cellular Adhesion ◽  
Wound Dressings ◽  
Poly Vinyl Alcohol ◽  
High Porosity ◽  
Hybrid Nanofibers

The management of chronic wounds is challenging. The factors that impede wound healing include malnutrition, diseases (such as diabetes, cancer), and bacterial infection. Most of the presently utilized wound dressing materials suffer from severe limitations, including poor antibacterial and mechanical properties. Wound dressings formulated from the combination of biopolymers and synthetic polymers (i.e., poly (vinyl alcohol) or poly (ε-caprolactone) display interesting properties, including good biocompatibility, improved biodegradation, good mechanical properties and antimicrobial effects, promote tissue regeneration, etc. Formulation of these wound dressings via electrospinning technique is cost-effective, useful for uniform and continuous nanofibers with controllable pore structure, high porosity, excellent swelling capacity, good gaseous exchange, excellent cellular adhesion, and show a good capability to provide moisture and warmth environment for the accelerated wound healing process. Based on the above-mentioned outstanding properties of nanofibers and the unique properties of hybrid wound dressings prepared from poly (vinyl alcohol) and poly (ε-caprolactone), this review reports the in vitro and in vivo outcomes of the reported hybrid nanofibers.

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