scholarly journals Caesarean delivery and risk of developing atopic diseases in children

2014 ◽  
Vol 54 (2) ◽  
pp. 94
Author(s):  
Anak Agung Tri Yuliantini ◽  
Mohammad Juffrie ◽  
Ketut Dewi Kumara Wati
Keyword(s):  
Family History ◽  
Caesarean Section ◽  
Caesarean Delivery ◽  
Case Control Study ◽  
Demographic Data ◽  
Multiple Logistic Regression ◽  
Atopic Diseases ◽  
Prick Test ◽  
History Of ◽  
Control Study

Background Caesarean delivery has been suggested to alterneonatal immune respon ses and increase the risk of atopicdiseases. Howevei; previous studies have reported inconsistentfindings.Objective To investigate a possible association between caesareandelivery and the development of atopic diseases in children.Methods This case-control study involved 100 children aged 3months-12 years, in Sanglah Hospital, Denpasai; Indonesia. Fiftyinfants and children with a confirmed diagnosis of atopic diseasesand 50 sex-paired controls (non-atopic infants and children)were enrolled. Demographic data was obtained, including modeof delivery and relevant history connected to atopic diseases.Skin prick test to four common aeroallergens was performed inall subjects. Possible confounding factors were considered in amultivariable logis tic regression model.Results Caesarean section was not significant as a risk factor foratopic diseases in a multivariate analysis [OR 2.4 (95%CI 0.7 to8.4; P=0.164)]. Howevei; multiple logistic regression analysisshowed that atopic diseases was significantly associated with apositive family history of atopy. Furthermore, caesarean sectionwas associated with a higher risk of atopic diseases in a subgroupanalysis for family history of atopy [OR= 4 (95%CI 1 to 16.2;P= 0.04)].Conclusion Children delivered by caesarean section and have afamily history of atopy have a 4-fo ld higher risk of atopic diseases.

scholarly journals The association between diabetes and thyroid cancer risk: a hospital-based case-control study in China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Meng Wang ◽  
Wei-Wei Gong ◽  
Feng Lu ◽  
Ru-Ying Hu ◽  
Qing-Fang He ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Family History ◽  
Case Control Study ◽  
Positive Family History ◽  
Case Control ◽  
Diabetes Duration ◽  
Family History Of Diabetes ◽  
Thyroid Cancer Risk ◽  
History Of ◽  
Control Study

Abstract Background Previous studies have indicated inconsistent relationships of diabetes with thyroid cancer risk, yet little is known in China. In this study, we aimed to investigate the associations between diabetes, diabetes duration and the risk of thyroid cancer in Chinese population. Methods A 1:1 matched case-control study was performed between 2015 and 2017 in Zhejiang Province including 2,937 thyroid cancer cases and 2,937 healthy controls. Odds ratios (ORs) with 95 % confidence intervals (CIs) for thyroid cancer were estimated in logistic regression models. Specific effects stratified by age, as well as sex, body mass index (BMI) and family history of diabetes were also examined. Results Overall, neither diabetes (OR = 0.75, 95 % CI: 0.21–2.73) nor diabetes duration (OR = 0.14, 95 % CI: 0.02–1.22 for diabetes duration ≦ 5 years; OR = 2.10, 95 % CI: 0.32–13.94 for diabetes duration > 5 years) was significantly associated with thyroid cancer. In stratified analyses, significant lower risk of thyroid cancer was observed among subjects with diabetes and shorter diabetes duration ( ≦ 5 years), but limited to those who were aged more than 40 years, female, overweight/obese and had positive family history of diabetes. Conclusions Diabetes and shorter diabetes duration were significantly associated with decreased risk of thyroid cancer in individuals characterized by older age, female sex, higher BMI and positive family history of diabetes.

scholarly journals Family history of hypertension increases risk of preeclampsia in pregnant women: a case-control study

2016 ◽  
Vol 35 (3) ◽  
pp. 181 ◽  
Author(s):  
Mulualem Endeshaw ◽  
Fantu Abebe ◽  
Melkamu Bedimo ◽  
Anemaw Asrat ◽  
Abebaw Gebeyehu ◽  
...  
Keyword(s):  
Family History ◽  
Pregnant Women ◽  
Case Control Study ◽  
Multiple Logistic Regression Analysis ◽  
Multiple Pregnancy ◽  
Case Control ◽  
Outcome Variable ◽  
History Of ◽  
Family History Of Hypertension ◽  
Control Study

Background <br />Preeclampsia is one of the leading causes of maternal and fetal morbidity and mortalities worldwide. Despite extensive research, the underlying cause of preeclampsia remains poorly understood. This study aimed to offer compelling evidence on the important risk factors of preeclampsia in Amhara region, Ethiopia.<br /><br />Methods<br />A case control study was conducted in public health facilities of Bahir Dar city from September 2014 to January 2015. A total of 453 (151 cases and 302 controls) pregnant women were enrolled in this study. Hemoglobin level and urinary tract infection (UTI) status were collected from clinical notes. Oral examination was performed by a dentist for detection of periodontal diseases. Univariate and multiple logistic regression analysis was conducted to determine the relationship of all the independent variables with the outcome variable. A p-value &lt;0.05 was declared statistically significant.<br /><br />Result<br />Advanced maternal age (AOR=4.79;95% CI 1.031-22.18), family history of hypertension (AOR=11.16;95% CI 5.41-41.43), history of diabetes mellitus (AOR=6.17;95% CI 2.11-20.33), UTI in the current pregnancy (AOR=6.58;95% CI 2.93-14.73), failure to comply with iron and folic acid supplement during pregnancy (AOR=8.32;95% CI 3.35-20.62), lack of exercise (AOR=3.33;95% CI 1.35-8.17), multiple pregnancy (AOR=4.05;95% CI 1.57-12.27), anemia (AOR=4.19;95% CI 1.27-13.92), and periodontal disease or gingivitis (AOR =3.51;95% CI 1.14-10.83) were associated with preeclampsia.<br /><br />Conclusion <br />Family history of hypertension was the most dominant risk factor for preeclampsia in pregnant women. Encouraging pregnant women to have health seeking behavior during pregnancy would provide a chance to diagnose preeclampsia as early as possible.

scholarly journals Case control study to assess the determinants of pregnancy induced hypertension among the antenatal mothers in Rajiv Gandhi women and children hospital at Puducherry

2020 ◽  
Vol 3 (2) ◽  
pp. 9-14
Author(s):  
Margaret A ◽  
Manjubala Dash
Keyword(s):  
Family History ◽  
Case Control Study ◽  
Pregnancy Induced Hypertension ◽  
Family History Of Diabetes ◽  
Induced Hypertension ◽  
History Of ◽  
Women And Children ◽  
Family History Of Hypertension ◽  
Pedal Edema ◽  
Control Study

Background: Hypertensive disorders of pregnancy are a major health problem to the world and is found to be the major cause of maternal morbidity and mortality accounting for nearly 10-15% 0f maternal deaths. Objective:To assess the determinants of Pregnancy induced hypertension. Methods: A case control study was conducted among pregnant women at Rajiv Gandhi Women and Children Hospital, Puducherry. 63 women with PIH were selected as cases and 63 normotensive pregnant women were taken as controls. The cases were selected by purposive sampling and the controls by simple random sampling. The tool consists of a self structured questionnaire which consists of the socio demographic factors and various other determinants assumed as a risk factor for PIH and some required information was also obtained from the case records. Statistics: The odds ratio and Chi-square test was used to determine the risk and association between PIH and the determinants respectively.Results: Primigravida (OR=2.826), multiple pregnancy (OR=2.629), presence of pedal edema (OR=54.836), family history of diabetes (OR=2.969), family history of hypertension (OR=5.5) Overweight (OR=2.12) and obesity (OR=6.52) were found to be significant risk factors of PIH. There was statistically significant association with history of abortion, parity, presence of pedal edema, use of contraceptives, family history of diabetes, family history of hypertension, prepregnancy Body mass index and PIH.

scholarly journals 346. Factors Associated with Hypertension in Young Adults with Perinatally-Acquired HIV Infection: a Case–Control Study

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S184-S184
Author(s):  
Patrick O’Neil ◽  
Patrick Ryscavage ◽  
Kristen A Stafford
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Family History ◽  
Case Control Study ◽  
Case Control ◽  
Systemic Hypertension ◽  
Early Management ◽  
Factors Associated ◽  
History Of ◽  
Control Study

Abstract Background The incidence of systemic hypertension (HTN) among perinatally-HIV-infected (PHIV) patients appears to increase as they enter adulthood. Among non-perinatally HIV-infected adults both traditional and HIV-associated risk factors have been found to contribute to HTN. Whether these same factors contribute to HTN in PHIV is unknown. The purpose of this study was to determine the socio-demographic, clinical, virologic, and immunologic factors associated with HTN among a cohort of PHIV adolescents and young adults, aged ≥18 years. Methods We conducted a case–control study among a population of 160 PHIV adults with and without HTN who were receiving care at the University of Maryland and aged 18–35 years as of December 31, 2017. Covariates assessed included traditional risk factors such as age, family history of HTN, and smoking, as well as HIV- and antiretroviral-associated covariates. Results We identified 49 HTN cases (30.6%) and 111 (69.4%) controls. There were no significant differences in the odds of most traditional (age, gender, race, family history of HTN, tobacco, alcohol, and/or other drug use) or HIV-associated (CD4 nadir <100 cells/mm3, individual ART exposure, ART interruption) risk factors among PHIV adults with HTN compared with those with no diagnosis of HTN. Cases had lower odds of a history of treatment with lopinavir/ritonavir (LPV/r). Cases had 3.7 (95% CI 1.11, 12.56) times the odds of a prior diagnosis of chronic kidney disease (CKD) compared with controls after controlling for CD4 nadir and ARV treatment history. Conclusion The results of this study suggest that most traditional and HIV-related risk factors do not appear to increase the odds of having HTN in this PHIV cohort. However, HTN among PHIV may be driven in part by CKD, and a focus on the prevention and early management of CKD in this group may be necessary to prevent the development of HTN. Additionally, there may be as yet unidentified risk factors for HTN among PHIV which require further exploration. Given the large and growing population of PHIV entering adulthood worldwide, it is imperative to explore risk factors for and effects of HTN in large, diverse PHIV populations. Disclosures All authors: No reported disclosures.

scholarly journals Family history of hormonal cancers and colorectal cancer risk: A case-control study conducted in Ontario

2009 ◽  
Vol 125 (4) ◽  
pp. 918-925 ◽  
Author(s):  
Ji-Hyun Jang ◽  
Michelle Cotterchio ◽  
Steven Gallinger ◽  
Julia A. Knight ◽  
Darshana Daftary
Keyword(s):  
Colorectal Cancer ◽  
Family History ◽  
Cancer Risk ◽  
Case Control Study ◽  
Case Control ◽  
Colorectal Cancer Risk ◽  
History Of ◽  
Control Study

scholarly journals The Risk Factors of Premature Myocardial Infarction: A Case Control Study in Iran

2016 ◽  
Vol 8 (11) ◽  
pp. 69 ◽  
Author(s):  
Mehdi Ehtesham ◽  
Ali Akbar Haghdoost ◽  
Seyed Vahid Ahmadi Tabatabaei ◽  
Hooman Bakhshandeh
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Family History ◽  
Case Control Study ◽  
Vascular Diseases ◽  
Current Smoking ◽  
History Of ◽  
Premature Myocardial Infarction ◽  
Cardio Vascular ◽  
Control Study

<p><strong>BACKGROUND:</strong> Although, our knowledge about the factors of cardio vascular diseases (CVD) is relatively acceptable, we have few publications about the risk factors of premature CVD particularly from developing countries such as Iran.</p><p><strong>OBJECTIVES:</strong> The present study is aimed to assess the risk of the modifiable risk factors of coronary heart disease (CHD) in the first cardiac attack of patients classified by age to check which risk factors might have a more significant impact to increase the risk of premature myocardial infarction (MI).</p><p><strong>METHODS:</strong> In a case control study, 122 and 266 cases and controls were recruited from one of the main referral centres in Tehran. Cases were those who were hospitalized because of their first myocardial infarction before the ages of 50 and 55 years in males and females respectively, and compared their risk factor profiles with those experienced first MI in higher age. Main independent variables in this study were: the demographic variables, distress, lipid profile, diabetes, smoking, family history of cardio vascular diseases, and physical activity.</p><p><strong>RESULTS: </strong>The results showed that distress (OR= 3.95), minorities (compare to Fars race) (OR= 3.30), higher education (OR= 1.30), family history of hyperlipidaemia (OR=1.89) significantly increased the risk of premature MI. We also found that family history of hypertension (OR=1.35), current smoking versus no smoking (OR=1.60), fast-food consumption (OR=1.48), non-alcoholic beverages (OR= 1.12) had also association with the risk of premature MI but only in crude model. We also found that regular physical activity (OR=0.42), ex-smoker versus current smoking (OR=0.27) and regular consumption of milk (OR=0.73) was protective against premature MI.</p><p><strong>CONCLUSION:</strong> Our findings demonstrate that the effect of most of risk factors were mostly related to their life-style (distress, smoking, physical inactivity and dietary pattern); while family history of diseases was also important.</p>

scholarly journals Reliability of Self-Reported Family History of Cancer in a Large Case–Control Study of Lymphoma

2006 ◽  
Vol 98 (1) ◽  
pp. 61-68 ◽  
Author(s):  
Ellen T. Chang ◽  
Karin Ekström Smedby ◽  
Henrik Hjalgrim ◽  
Bengt Glimelius ◽  
Hans-Olov Adami
Keyword(s):  
Family History ◽  
Case Control Study ◽  
Case Control ◽  
Family History Of Cancer ◽  
History Of ◽  
Control Study ◽  
History Of Cancer ◽  
Large Case
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