scholarly journals The Novel "Poor Folk" in the Context of Dostoevsky's Letters from the time of the Kuznetsk Events

2021 ◽  
pp. 88-101
Author(s):  
Elena Trukhan
Keyword(s):  
Creative Thinking ◽  
High Standard ◽  
Artistic Expression ◽  
The Novel ◽  
Great Literature ◽  
Self Reflection ◽  
Epistolary Novel ◽  
Penal Colony ◽  
Expression Characteristic

The article shows the connection between the epistolary novel "Poor Folk", the events of the biography of F. M. Dostoevsky and his epistolary legacy of the Kuznetsk period (1855-1857). The novel "Poor Folk" created in after -penal colony time is considered as a high standard for the author, as a self-reflection. The letters of F. M. Dostoevsky from the time of the Kuznetsk events, where there are several excerpts about "Poor Folk", are presented as a workbook, a creative laboratory, where the writer develops a new quality of artistic expression characteristic of his mature works. For Dostoevsky, the novel "Poor Folk" is not just a brilliant debut that opened the way to "great literature", but also a text that has prophetic and life-creating modes, and has connections with the events of his life in Kuznetsk. Repeated reference to it, the presence of several versions of the novel, speaks about the peculiarities of the author's creative thinking and the significance of this work for the writer.

ДИАГНОСТИКА ХРОНИЧЕСКИХ ИНДУЦИРОВАННЫХ КРАПИВНИЦ

2019 ◽  
pp. 5-13
Author(s):  
E.Yu. Borzova
Keyword(s):  
Quality Of Life ◽  
Biological Therapy ◽  
Treatment Algorithm ◽  
The Novel ◽  
International Guidelines ◽  
Systemic Reactions ◽  
Significant Impairment ◽  
Challenge Tests

Хронические индуцированные крапивницы имеют важное социальноэкономическое значение вследствие риска развития системных реакций и значительного снижения качества жизни пациентов. Диагностика хронических индуцированных крапивниц основывается на анамнестических данных и проведении провокационных тестов. Современный протокол ведения больных хронической крапивницей включает применение неседативных антигистаминных препаратов. Международные согласительные документы по лечению крапивницы рекомендуют 4кратное увеличение суточной дозы неседативных антигистаминных препаратов при их неэффективности в стандартных дозах. Данные метаанализа указывают на эффективность омализумаба при хронических индуцированных крапивницах. В перспективе ожидается расширение арсенала генноинженерной биологической терапии хронических индуцированных крапивниц.Chronic inducible urticarias are characterized by the risks of systemic reactions and a significant impairment of patients quality of life. The diagnosis of chronic inducible urticarias relies on the patients history and the challenge tests. A treatment algorithm for the management of chronic inducible urticarias includes nonsedating antihistamines as a firstline treatment. The international guidelines for the management of chronic inducible urticarias recommend updosing of nonsedating antihistamines up to four fold if standard doses are not effective. The metaanalysis suggests the efficacy of omalizumab in chronic inducible urticarias. In the prospect, the novel options of biological therapy for chronic inducible urticarias are expected.

ДИАГНОСТИКА ХРОНИЧЕСКИХ ИНДУЦИРОВАННЫХ КРАПИВНИЦ

2019 ◽  
Author(s):  
E.Yu. Borzova
Keyword(s):  
Biological Therapy ◽  
Meta Analysis ◽  
Treatment Algorithm ◽  
The Novel ◽  
First Line ◽  
Systemic Reactions ◽  
Significant Impairment ◽  
Challenge Tests ◽  
First Line Treatment

Хронические индуцированные крапивницы имеют важное социально-экономическое значение вследствие риска развития системных реакций и значительного снижения качества жизни пациентов. Диагностика хронических индуцированных крапивниц основывается на анамнестических данных и проведении провокационных тестов. Современный протокол ведения больных хронической крапивницей включает применение неседативных антигистаминных препаратов. Международные согласительные документы по лечению крапивницы рекомендуют 4-кратное увеличение суточной дозы неседативных антигистаминных препаратов при их неэффективности в стандартных дозах. Данные мета-анализа указывают на эффективность омализумаба при хронических индуцированных крапивницах. В перспективе ожидается расширение арсенала генно-инженерной биологической терапии хронических индуцированных крапивниц.Chronic inducible urticarias are characterized by the risks of systemic reactions and a significant impairment of patients quality of life. The diagnosis of chronic inducible urticarias relies on the patients history and the challenge tests. A treatment algorithm for the management of chronic inducible urticarias includes nonsedating antihistamines as a first-line treatment. The international guidelines for the management of chronic inducible urticarias recommend updosing of nonsedating antihistamines up to four fold if standard doses are not effective. The meta-analysis suggests the efficacy of omalizumab in chronic inducible urticarias. In the prospect, the novel options of biological therapy for chronic inducible urticarias are expected.

scholarly journals Identification of the State of Electrical Appliances with the Use of a Pulse Signal Generator

Energies ◽  
2021 ◽  
Vol 14 (3) ◽  
pp. 673
Author(s):  
Augustyn Wójcik ◽  
Piotr Bilski ◽  
Robert Łukaszewski ◽  
Krzysztof Dowalla ◽  
Ryszard Kowalik
Keyword(s):  
Measurement System ◽  
Cross Correlation ◽  
Pulse Signal ◽  
Signal Generator ◽  
Experimental Results ◽  
The Novel ◽  
End User ◽  
Standard Classification ◽  
Electrical Appliance

The paper presents the novel HF-GEN method for determining the characteristics of Electrical Appliance (EA) operating in the end-user environment. The method includes a measurement system that uses a pulse signal generator to improve the quality of EA identification. Its structure and the principles of operation are presented. A method for determining the characteristics of the current signals’ transients using the cross-correlation is described. Its result is the appliance signature with a set of features characterizing its state of operation. The quality of the obtained signature is evaluated in the standard classification task with the aim of identifying the particular appliance’s state based on the analysis of features by three independent algorithms. Experimental results for 15 EAs categories show the usefulness of the proposed approach.

scholarly journals Pediatric Endocrinology in the Time of COVID-19: Considerations for the Rapid Implementation of Telemedicine and Management of Pediatric Endocrine Conditions

2020 ◽  
Vol 93 (6) ◽  
pp. 343-350
Author(s):  
Molly O. Regelmann ◽  
Rushika Conroy ◽  
Evgenia Gourgari ◽  
Anshu Gupta ◽  
Ines Guttmann-Bauman ◽  
...  
Keyword(s):  
Patient Care ◽  
Care Patient ◽  
The Novel ◽  
Patient Privacy ◽  
Pediatric Endocrinology ◽  
Quality Of Patient Care ◽  
Care Outcomes ◽  
Novel Coronavirus ◽  
The Impact

<b><i>Background:</i></b> Pediatric endocrine practices had to rapidly transition to telemedicine care at the onset of the novel coronavirus disease 2019 (COVID-19) pandemic. For many, it was an abrupt introduction to providing virtual healthcare, with concerns related to quality of patient care, patient privacy, productivity, and compensation, as workflows had to change. <b><i>Summary:</i></b> The review summarizes the common adaptations for telemedicine during the pandemic with respect to the practice of pediatric endocrinology and discusses the benefits and potential barriers to telemedicine. <b><i>Key Messages:</i></b> With adjustments to practice, telemedicine has allowed providers to deliver care to their patients during the COVID-19 pandemic. The broader implementation of telemedicine in pediatric endocrinology practice has the potential for expanding patient access. Research assessing the impact of telemedicine on patient care outcomes in those with pediatric endocrinology conditions will be necessary to justify its continued use beyond the COVID-19 pandemic.

scholarly journals Regenerative Endodontic Procedures: An Umbrella Review

2021 ◽  
Vol 18 (2) ◽  
pp. 754
Author(s):  
Luísa Bandeira Lopes ◽  
João Albernaz Neves ◽  
João Botelho ◽  
Vanessa Machado ◽  
José João Mendes
Keyword(s):  
Methodological Quality ◽  
Primary Outcome ◽  
Web Of Science ◽  
High Standard ◽  
Measurement Tool ◽  
Clinical Protocols ◽  
Umbrella Review ◽  
Electronic Database Search ◽  
Specific Section

The Regenerative Endodontic Procedure (REP) is a biologically based method in which a damaged pulp–dentin complex is replaced by a new vital tissue. This umbrella review aimed to critically assess the available systematic reviews (SRs) on REP. An electronic database search was conducted (PubMed-Medline, CENTRAL, Scielo, Web of Science, and LILACS) until December 2020. Studies were included if they were an SR on REP. The Risk of Bias (RoB) of SRs was analyzed using the Measurement Tool to Assess SRs criteria 2 (AMSTAR2). The primary outcome was the methodological quality in each specific section of REP protocols and outcomes. From 403 entries, 29 SRs were included. Regarding the methodological quality, ten studies were of critically low, three of low, fourteen of moderate, and two were rated as high quality. The quality of evidence produced by the available SRs was not favorable. Future high standard SRs and well-designed clinical trials are warranted to better elucidate the clinical protocols and outcomes of REP.

scholarly journals Novel Protein-Repellent and Antibacterial Resins and Cements to Inhibit Lesions and Protect Teeth

2019 ◽  
Vol 2019 ◽  
pp. 1-11 ◽  
Author(s):  
Li Cao ◽  
Junling Wu ◽  
Qiang Zhang ◽  
Bashayer Baras ◽  
Ghalia Bhadila ◽  
...  
Keyword(s):  
Orthodontic Treatment ◽  
The Novel ◽  
Dental Resin ◽  
Biofilm Growth ◽  
New Class ◽  
Dental Resins ◽  
Wide Range ◽  
Oral Biofilms ◽  
One Year

Orthodontic treatment is increasingly popular as people worldwide seek esthetics and better quality of life. In orthodontic treatment, complex appliances and retainers are placed in the patients’ mouths for at least one year, which often lead to biofilm plaque accumulation. This in turn increases the caries-inducing bacteria, decreases the pH of the retained plaque on an enamel surface, and causes white spot lesions (WSLs) in enamel. This article reviews the cutting-edge research on a new class of bioactive and therapeutic dental resins, cements, and adhesives that can inhibit biofilms and protect tooth structures. The novel approaches include the use of protein-repellent and anticaries polymeric dental cements containing 2-methacryloyloxyethyl phosphorylcholine (MPC) and dimethylaminododecyl methacrylate (DMAHDM); multifunctional resins that can inhibit enamel demineralization; protein-repellent and self-etching adhesives to greatly reduce oral biofilm growth; and novel polymethyl methacrylate resins to suppress oral biofilms and acid production. These new materials could reduce biofilm attachment, raise local biofilm pH, and facilitate the remineralization to protect the teeth. This novel class of dental resin with dual benefits of antibacterial and protein-repellent capabilities has the potential for a wide range of dental and biomedical applications to inhibit bacterial infection and protect the tissues.

Standard minimi di qualitŕ: un approccio teorico

2012 ◽  
pp. 29-41
Author(s):  
Grassi Iacopo
Keyword(s):  
High Standard ◽  
Policy Instrument ◽  
Quality Standard ◽  
Average Quality ◽  
Proposed Model ◽  
Positive Externality ◽  
Experience Good ◽  
The Government ◽  
Minimum Quality

At least since Akerlof (1970), asymmetric information in the case of experience goods has been a central issue in the economic literature. This paper studies regulation in markets where the quality of the experience good is never completely verifiable by consumers even after purchase. In the proposed model firms can decide the quality of the good: always producing a high quality good creates a positive externality in the market, but it causes an incentive to the firms to deviate and produce low quality goods. The main policy instrument for the government, in order to maximize Social Welfare, is to fix a minimum quality standard, but imposing a too high standard might, in some cases, lower the average quality of the good in the market.

Methods Of Solving Various Types Of Problems From Algebra To Science

2021 ◽  
Vol 03 (05) ◽  
pp. 1-6
Author(s):  
Yusup Ganievich Mahmudov ◽  
◽  
Yunusjon Abdiravupovich Khakkulov ◽  
◽  
◽  
...  
Keyword(s):  
Creative Thinking ◽  
Interactive Methods ◽  
Educational Institutions ◽  
Teaching Mathematics ◽  
Professional Orientation ◽  
Quality Of Teaching ◽  
Foreign Countries ◽  
Development Of Students ◽  
Mathematics And Physics

The active use of interactive methods, including the widespread use of trends in improving the quality of teaching mathematics and physics in educational institutions of many foreign countries, which are recognized for the high quality of teaching, contributes to the development of students skills in solving and choosing problems in physics in the course of mathematics, the formation of their skills of creative thinking and professional orientation on the basis of interdisciplinary connections. Therefore, the article describes a methodology for choosing, constructing and solving various types of interdisciplinary algebra problems.

Job

1975 ◽  
Author(s):  
Marvin H. Pope
Keyword(s):  
Special Interest ◽  
World Literature ◽  
High Standard ◽  
Dead Sea ◽  
Middle Section ◽  
Concerted Effort ◽  
Book Of Job ◽  
Divine Justice ◽  
Traditional Image

This third edition of the Anchor Bible Book Of Job (Volume 15 in the series) contains numerous new, revised or augmented notes. Of special interest is the inclusion of readings from the earliest translation of the Book Of Job, the recently published Targum (Aramaic translation) recovered from Cave XI of Khirbet Qumran, in the Judean Wilderness near the Dead Sea, perhaps the version which was suppressed by Rabbi Gamaliel. The Book Of Job is one of the indisputably great works of world literature. The story is well-known: a prosperous and happy man, distinguished for rectitude and piety, falls victim to a series of catastrophes. And the occasion (if not the reason) for these undeserved calamities: Satan's challenge to Yahweh to test the sincerity of Job's faith. It is by now proverbial to refer to the patience of Job. Yet this traditional image derives only from the Prologue and the Epilogue of the book. But the Job who confronts us in the long middle section is anything but patient. His outcries against God raise the question of theodicy, or divine justice, which occupies the greater portion of Job's Dialogue with his comforters. But it is inevitably as literature that Job must be read and enjoyed. This translation is marked by a concerted effort to capture as much as possible the poetic and metrical characteristics of the original Hebrew: the result is a version notable for its accuracy and directness. The experience of reading the Book Of Job in this translation, then, is to rediscover an exceedingly eloquent masterpiece. In the terse, rhythmic quality of the translation, the incisive comprehensiveness of the introduction and notes, Job maintains the high standard of scholarship, literateness, and readability established in The Anchor Bible.

scholarly journals Renovation and Reuse of Reactive Dyeing Effluent by a Novel Heterogeneous Fenton System Based on Metal Modified PTFE Fibrous Catalyst/H2O2

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Bing Li ◽  
Yongchun Dong ◽  
Zhizhong Ding ◽  
Yiming Xu ◽  
Chi Zou
Keyword(s):  
Reactive Dyes ◽  
Cotton Fabrics ◽  
Molar Ratio ◽  
The Novel ◽  
Heterogeneous Fenton ◽  
Reactive Dyeing ◽  
Toc Removal ◽  
Dyeing Effluent ◽  
Fenton System

Cu-Fe bimetallic grafted polytetrafluoroethylene (PTFE) fiber complexes were prepared and optimized as the novel heterogeneous Fenton catalysts for the degradation of reactive dyes under UV irradiation. Cotton fabrics were dyed with three reactive dyes, namely, Reactive Red 195, Reactive Yellow 145, and Reactive Blue 222, in tap fresh water using exhaustion process. The spent dyeing effluents were then collected and degraded with the optimized Cu-Fe bimetallic grafted PTFE fiber complex/H2O2system. The treated dyeing effluents were characterized and reused for the dyeing of cotton fabrics through the same process. The effect of reuse process number on quality of the dyed cotton fabrics was examined. The results indicated that the Cu-Fe bimetallic modified PTFE fiber complex with a Cu/Fe molar ratio of 2.87 was found to be the most effective fibrous catalyst, which enhanced complete decolorization of the treated dyeing effluents with H2O2in 4 h. However, the TOC removal for the treated dyeing effluents was below 80%. The dyeing quality was not affected for three successive cycles. The increase in residual TOC value influences fourth dyeing cycle. Further TOC reduction of the treated effluents is needed for its repeated reuse in more than three dyeing cycles.

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