scholarly journals PROFILE OF CULTURE POSITIVE ENTERIC FEVER IN CHILDREN ADMITTED IN A TERTIARY CARE HOSPITAL

2017 ◽  
Vol 6 (88) ◽  
pp. 6112-6117
Author(s):  
Mullainathan Sucindar ◽  
Seshanganur Sitaraman Kumaran
Author(s):  
Venkateswaramurthy N ◽  
Ashli Raj V ◽  
Nisharani SS ◽  
Limna AL ◽  
Chandini S ◽  
...  

Wound infection has always been a major complication of surgery and trauma. The aim of our study was to determine the bacteriology of wound infections and to study the antibiotic susceptibility pattern of the isolates. The study was conducted in tertiary care hospital, Erode. The design of the study was a prospective type. Pus swabs / specimens were collected from hospitalized patients who developed wound infections. Bacterial pathogens were identified by conventional biochemical methods according to standard microbiological techniques. Antimicrobial susceptibility was performed on Muller – Hinton agar by the standard disk diffusion method. The incidence of wound infection was more common in males (63%) than in females (37%). Out of 100 culture positive samples, 61 samples were collected from diabetic ulcer patients, 20 samples were from ulcer patients, and 19 samples were from post operative patients. Of the 100 samples (culture positive), 71% collected samples showed mono-microbial growth, 29% showed two type of microbial growth. The prevalence of S. aureus (62.87%) from different wound infections was found to be high, followed by E.coli (48.65%), Klebsiella (30.21%), Pseudomonas (22.16%). Organisms showed diversity in the sensitivity pattern towards the antibiotics tested. High level of sensitivity was observed to Imipenem, Piperacillin tazobactum and Amikacin. High level of resistance was observed to Cephalosporins and Penicillin derivatives. We concluded that the sensitivity pattern of the antibiotics is not based on the infection site but on the type of organisms. This study gives us an insight to the current state of causative pathogens and their sensitivity to different antibiotics used in tertiary care hospital, Erode. The data of this study may be used to determine trends in antimicrobial susceptibilities and to modify antibiotic policy of the Hospital.


2021 ◽  
Vol 9 (1) ◽  
pp. 15
Author(s):  
Sheenam Gazala ◽  
Mohmad Saleem Chesti ◽  
Syed Mushfiq

Background: Current study aimed at s to delineate the etiology and clinical parameters associated with AUFI presenting to emergency department in a tertiary care hospital.Methods: This was a prospective hospital based study carried out at emergency medicine, SKIMS hospital, Soura Kashmir, India July 2017 to august 2018. Patients with acute undifferentiated fever were enrolled. Descriptive statistics were calculated in terms of mean±SD for continuous variables like age of the patients and duration of fever, Frequency and percentage were used to analyse categorical variables such as causes of fever and gender, while as descriptive analysis was calculated in terms of mean±SD for continuous variables like age of the patients and duration of fever.Results: Total numbers of patients included were 174, among these 112 (64.3%) were males and 62 (35.6%) were females. Most patients were diagnosed enteric fever (N=59, 33.9%) followed by UTI (N=25, 14.3%) dengue (N=12, 6.8%) and malaria (N=8, 4.5%) while rest of cases were associated with other viral illnesses (N=70, 40.5%) based on clinical basis and inconclusive laboratory results.Conclusions: Enteric fever was found to be the most common cause of acute undifferentiated fever followed by dengue and other viral illnesses, although causes and clinic spectrum of AUFI is varied.


2021 ◽  
Vol 4 (2) ◽  
Author(s):  
Soma Halder ◽  
◽  
Md. Ekhlasur Rahman ◽  
Mst Mukta Sarker ◽  
Fabia Hannan Mone ◽  
...  

Enteric fever remains a major public health problem in developing countries like Bangladesh. Improvement in the health facility, vaccination, and health-related awareness program the incidence of enteric fever among children is not decreased. The study aimed to find out the risk factors for enteric fever in hospitalized children in a tertiary care hospital. Methodology: We conducted a hospital-based case-control study to identify the risk factors in children residing in Dhaka city. We enrolled 50 enteric fever cases as a case group and 50 age-matched febrile patients as a control group. Result: Out of 50 cases, 2 patients were below one year and most of them were pre-school aged 26(52%). Univariate analysis showed that enteric fever is more who take food with the help of the mother and caregiver (OR=7.1); 95% CI= 26.7 -61.3) and never or rarely wash hands before preparing food and before feeding (OR= 5.7; 95% CI= 23.2 -52.8). Cases were eating outdoors at the mobile food vendors and consuming ice-cream regularly (OR=2.28; 95% CI=1- 39) whereas the control group also took street food but less frequently. Conclusion: Enteric fever is an exclusive food and water-borne systemic disease and one of the major public health problems in Bangladesh. Not only overcrowding, unsafe drinking water are the common risk factors but also hand washing both children and caregiver, poor food habit is the important risk factors. So, health education to children and food handlers may reduce the incidence of enteric fever in children.


2020 ◽  
Vol 8 (8) ◽  
pp. 1927-1931
Author(s):  
Mizanur Rahman ◽  
ASM Nawshad Uddin Ahmed ◽  
Jafar Iqbal ◽  
Mohammad Abdullah Al Mamun ◽  
Nazia Hossain ◽  
...  

2018 ◽  
Vol 61 (4) ◽  
pp. 125-130 ◽  
Author(s):  
Anuradha Makkar ◽  
Shilpi Gupta ◽  
Inam Danish Khan ◽  
Rajiv Mohan Gupta ◽  
KS Rajmohan ◽  
...  

Introduction: Enteric-fever is a major public-health problem in developing countries emerging as multidrug-resistant, Nalidixic-acid resistant and extremely drug-resistant Salmonella (Pakistan, 2016), has intensified the use of WHO watch/reserve group antimicrobials such as azithromycin and meropenem. Methods: This ambispective-study was conducted on 782 non-repeat blood-culture isolates of S. Typhi, S. Paratyphi A and S. Paratyphi B obtained from 29,184 blood cultures received at a 1000-bedded tertiary-care hospital of North-India from 2011–2017. Identification and antibiograms were obtained by Vitek-2 compact and Kirby-Bauer’s disc diffusion with resistance to ampicillin, chloramphenicol and cotrimoxazole being labeled as multidrug-resistant. Decreased ciprofloxacin-susceptibility and ciprofloxacin-resistance were defined as MIC 0.125–0.5 and >1 μg/ml. Results: S. Typhi and S. Paratyphi A in a ratio of 3.9:1 were seen between July–September predominantly distributed between 6–45 year age group. Resistance to co-trimoxazole, chloramphenicol, ceftriaxone and azithromycin was 6.1%, 13.8%, 16.1 and 5.78% respectively. Multidrug-resistant S. typhi and S. paratyphi A were 2.73% and 1.91% respectively. Conclusion: Enteric-fever is a major public-health problem in India. Emergence of multidrug-resistant, Nalidixic-acid resistant and extremely-drug resistant Salmonella mandates ongoing surveillance for targeted empirical therapy and containment of spread. Repeated epidemics call for water, sanitation, hygiene and vaccination strategies to sustain herd-immunity.


Author(s):  
Tabindah Jahan ◽  
Anjum Farhana ◽  
Farhat Kanth

Background: Dermatophyte infections are a global health problem but very neglected in Kashmir. India. This work aimed at determining prevalence and spectrum of dermatophytosis isolated from patients attending tertiary care hospital Srinagar. Kashmir.Methods: A total of 510 samples of skin, hair and nail scrapings were collected and processed using standard microscopy (KOH) and cultural methods as per the standard protocol.Results: Out of 510 samples collected, 272 (53.33%) patients were confirmed cases of dermatophytosis (confirmed clinically and on fungal culture). The prevalence of dermatophytosis was significantly associated with age groups of participants with higher infection among those aged 18-32 which accounted for 35.29%, followed by age group 1-17 with 30.14%. Out of 510 samples, 110 ( 21.56%) were both KOH (microscopy) and culture positive, 162 (31.76%) cases were only culture positive and 130 (25.49%) clinical samples were only positive for fungal elements on microscopy. 133 (26.07%) fungal isolates were obtained which included both dermatophyte and non-dermatophytic fungi(excluded in this study). T. mentagrophytes had highest distribution 40.44% among dermatophytes species and T. Unguium 114 (41.96%) accounted for most common site for dermatophytic infections. Poor hygiene was predominant risk factor in 143 cases (52.57%). Patients from lower socioeconomic status were affected more than others (34.92%).Conclusions: In this study we have focused to determine the prevalence, clinical pattern and pathogenic profile of dermatophytosis according to the age, gender, site, and fungal distribution. Improvization of these conditions more accurately can result in decreased incidence of dermatophytosis in this area. 


Author(s):  
Swapnil Gautam ◽  
Suraj Purushothaman ◽  
Kinjal P. Patel ◽  
Ajay P. Sankhe ◽  
Madhuri R. Mahadik

Background: Asterion Introduction: Enteric fever is a major concern in developing country. It is predominantly caused by serovars typhi and paratyphi of Salmonella enterica. Recently, an upsurge in antimicrobial resistant strains has worsened the management of enteric fever. So, aim of present study is to evaluate the clinical profile, antibiotic sensitivity and prescription pattern in blood culture proven cases of enteric fever in pediatric and adult patients.Methods: Single centre, prospective study was conducted at a tertiary care hospital. Demographic and clinical details of blood culture proven enteric fever admitted in hospital were collected over the period from August 2016 to November 2018.Results: Total 58 blood cultures grew Salmonella spp. , amongst them 84.48 % had growth of Salmonella typhi. Blood culture was sent after a mean period of 9 days and 10 days of fever in pediatric and adult patients respectively. All isolates of S. paratyphi A were pansusceptible, whereas 36.73 % isolates of S. typhi were multidrug resistant and nalidixic acid resistant. 68.97% patients received antibiotics before admission. The difference between mean time to defervescence in patients who received ceftriaxone and those who received more than one antibiotic was not statistically significant. (P value 0.87)Conclusion: Blood cultures are the important diagnostic tool to identify multidrug resistant Salmonellae. Study showed that combination therapy was not statistically superior and awareness of local antimicrobial susceptibility pattern significantly helps for better management of the patients.


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