EPIDEMIOLOGICAL TREND IN SUPERFICIAL FUNGAL INFECTIONS AT A TERTIARY CENTRE IN WESTERN UTTAR PRADESH, INDIA

Background: Deep mycoses which includes subcutaneous mycoses and systemic mycoses, accounts for about 1% of the all the fungal infections seen in human beings. Though rare, these infections assume significance due to the increased morbidity and mortality associated with them. The objective of the study was to study the incidence, clinical presentation, aetiological agents and histopathological findings of deep mycoses in patients attending the mycology section, department of dermatology of a tertiary centre in Chennai.Methods: All Patients with clinical suspicion of deep mycoses who presented to mycology section during the period from November 2015 to September 2016 were screened. The samples from these patients were subjected to direct microscopy by potassium hydroxide wet mount, culture and histopathology.Results: Among the 8250 patients who attended mycology OPD, 41 patients (0.5%) had deep mycoses. The commonly affected age group was 41-50 yrs (29.7%). Males (73.2%) were predominantly affected. Of the 41 patients, 26.8% were immunocompromised. 37 patients (90.2%) had subcutaneous infection and 4 (9.8%) had opportunistic mycoses. Mycetoma (43.2%) was the most common subcutaneous mycoses. Mucormycosis (75%) and aspergillosis (25%) were the opportunistic mycoses observed. KOH positivity was 100%, while culture positivity was 65.7%. Madurella mycetomatis, Phialophora verrucosa, Rhizopus arrhizus and Aspergillus fumigatus were the common organisms isolated in this study.Conclusions: Mycetoma is the most common subcutaneous mycoses in this part of India. Eumycetoma is more common than actinomycetoma. Phaeohyphomycosis is on the rise. Simple KOH examination would pave way for an early diagnosis and prompt treatment of deep mycoses.

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Epidemiological characterization of dermatophytes at a tertiary care hospital in Eastern Uttar Pradesh, India

Current Medical Mycology ◽

10.18502/cmm.5.1.530 ◽

2019 ◽

Author(s):

Ankur Kumar ◽

Vandana Upadhyay ◽

Amresh K. Singh ◽

Jayesh Pandey

Keyword(s):

Low Socioeconomic Status ◽

Fungal Infections ◽

Tertiary Care ◽

Uttar Pradesh ◽

Common Species ◽

Personal Hygiene ◽

Clinical Samples ◽

Care Hospital ◽

Direct Microscopic Examination ◽

Superficial Mycosis

Background and Purpose: Superficial mycosis is more prevalent in tropical and subtropical countries, such as India. Regarding this, the present study was conducted to determine the epidemiology of superficial mycosis and identify the most common dermatophytic species in this region. Materials and Methods: For the purpose of the study, a total of 220 skin scraping, nail, and hair root specimens were collected. Direct microscopic examination was performed using potassium hydroxide mount. Additionally, the samples were inoculated onto Sabouraud dextrose agar (SDA) and dermatophyte test medium (DTM). The fungal colony of each isolates was stained with lactophenol cotton blue mount, and observed under microscope for species identification. Results: Out of 220 isolates, 172 samples, obtained from 108 males 64 females, were positive for skin fungal infections by either KOH mount or culture. Furthermore, 113 isolates were identified as dermatophytes, while 59 samples were found to be non-dermatophytes. Among the dermatophytes isolated from different clinical samples, Trichophyton verrucosum (42/113, 38%) was the most common species, and Tinea corporis was the most common infection (36.2%). Conclusion: As the findings indicated, dermatophytes had an isolation rate of 78%, which is higher than normal. This can be due to the fact that the majority of the patients were from a rural background (71.7%) with a low socioeconomic status and poor personal hygiene who were exposed to climatic changes.

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Doppler study of peripheral blood flow in lower extremity of diabetic patients with or without ischemic symptoms in tertiary centre

International Surgery Journal ◽

10.18203/2349-2902.isj20191065 ◽

2019 ◽

Vol 6 (4) ◽

pp. 1137

Author(s):

Shashank Shekhar Tripathi ◽

Rahul Singh ◽

Ankur Tripathi ◽

Himansha Pandey

Keyword(s):

Uttar Pradesh ◽

Physical Characteristics ◽

Diabetic Patients ◽

Peripheral Blood Flow ◽

Asymptomatic Group ◽

Medical College ◽

Tertiary Centre ◽

Doppler Study ◽

Vascular Insufficiency ◽

Duration Of Disease

Background: Doppler ultrasonic velocity detector which is least expensive and most versatile instrument. This technique is particularly helpful to establish the diagnosis of vascular insufficiency in clinically suspected cases of vascular disease and to predict the therapeutic results and follow up.Methods: The present study was conducted in MLN Medical College and SRN Hospital, Allahabad, Uttar Pradesh, India. Patients of either sex suffering from diabetes with or without ischemic symptoms, who presented themselves. Study consisted of 50 subjects, which were matched by age, sex and all physical characteristics. Among the 50 subjects, 20 were suffering from diabetes and had ischemic symptoms like intermittent or rest pain and gangrene. Another set of 20 patients in this study group were of diabetes without any ischemic symptoms. Remaining 10 patients were controls i.e., they were comparable in physical characteristics like age, sex, height and weight. They had never smoked neither had any vascular disease.Results: In this study, peak incidence of diabetic foot lesion was 6th decade and about 20% of female patient had foot lesion. In this study, the mean duration of disease in diabetic with ischemic symptoms was 9.6 years, while in asymptomatic group it was 6.9 years. It showed that as duration of disease increases, there is more probability for appearance of ischemic symptoms and foot involvement.Conclusions: In diabetics without ischemic symptoms, most of the doppler wave patterns are triphasic and biphasic, while in diabetics with ischemic symptoms biphasic and monophasic waves are predominantly seen.

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Isolation of Dermatophytes from Superficial Fungal Infections at Badaun, Uttar Pradesh

Recent Research Advances in Biology Vol. 5 ◽

10.9734/bpi/rrab/v5/8246d ◽

2021 ◽

pp. 169-174

Author(s):

Pankaj Saxena

Keyword(s):

Fungal Infections ◽

Uttar Pradesh

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Zygomycoses - urgency in diagnosis

International Journal of Basic and Applied Sciences ◽

10.14419/ijbas.v4i4.5004 ◽

2015 ◽

Vol 4 (4) ◽

pp. 371

Author(s):

Dilip Abraham ◽

Aroma Oberoi ◽

Eshani Dewan ◽

Sangeetha Mohan

Keyword(s):

Fungal Infections ◽

Common Species ◽

Term Treatment ◽

Diabetic Patients ◽

Absidia Corymbifera ◽

Tertiary Centre ◽

Long Term Treatment ◽

Diagnostic Modalities ◽

Chronic Wound Infections

Introduction: Zygomycoses is an angioinvasive infection most commonly seen in immunocompromised and diabetic patients. We undertook this study to determine the prevalence of Zygomycoses, in patients with a suspected Invasive Zygomycoses Infection in a tertiary centre and to identify the most common species isolated from culture.Materials and Methods: A retrospective analysis was done from January 1, 2012 to December 8, 2014; the clinical data of the suspected patients and the positive cultures were collected.Results and Discussion: A total of 50 samples of 27 patients with suspected Zygomycoses were sent during the 3 year period. In 25 of these patients, the samples sent were tissue biopsies from nasal cavity and 2 wound swabs from burns. Of these, 18 tissue biopsies of 13 patients and two wound swabs were detected positive for Zygomycetes. (2-Absidia corymbifera; 1-Rhizopus, 15-Mucor). Of the remaining 12 patients whose cultures were negative, 1–bacterial 1–bacterial sinusitis, 5-Invasive aspergillosis; 6-treated as Invasive fungal infections due to Zygomycetes as the imaging diagnostics and histopathological features favored that diagnosis. The majority of the patients (80%) were diabetic, and the two from the burn unit were under long-term treatment for chronic wound infections. Multiple diagnostic modalities must be used in view of the aggressive nature of the disease, but microbiological diagnosis remains the Gold Standard.

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Clinical profile of ACS patients and their outcome at tertiary centre in north-eastern Uttar Pradesh, India

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20181408 ◽

2018 ◽

Vol 5 (3) ◽

pp. 487

Author(s):

M. Sarkari ◽

Ajeet P. Singh

Keyword(s):

Wall Motion ◽

Uttar Pradesh ◽

Regional Wall Motion ◽

Coronary Syndrome ◽

Tertiary Centre ◽

Recurrent Angina ◽

North Eastern ◽

Artery Disease ◽

Eastern Uttar Pradesh

Background: Coronary artery disease (CAD) is a major cause of death in India. This study determined the characteristics, treatment and outcomes of acute coronary syndrome (ACS) at tertiary centre in north eastern Uttar Pradesh in India.Methods: We carried out observational study with 60-days follow-up of 80 ACS patients. Data are collected on different variables including Blood pressure, pulserate, BNP, TROP I, CKMB, patient’s demography, risk factors, laboratory values at admission and repeated as and when required. Results: T In our study most common presentation was chest pain, majority of patients presented after 12 hour of onset of symptoms, elevation of TROP I was higher in STEMI than NSTEMI, most common complication in NSTEMI was recurrent angina and in STEMI patients was heart failure, total 15 patients expired during study 11 during hospitalization and 4 patients within 60days of follow up, thrombolysed patients has less chances of regional wall motion abnormality.Conclusions: In our study elevation of TROP I was more in STEMI and there was less chances of RWMA in thrombolysed patients.

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Taxonomic note on a rare fish infecting freshwater mould Achlya ambisexualis Raper 1939 (Achlyaceae) isolated from Chandraprabha dam, Uttar Pradesh, India

Indian Journal of Fisheries ◽

10.21077/ijf.2018.65.1.68489-12 ◽

2018 ◽

Vol 65 (1) ◽

Cited By ~ 1

Author(s):

Manish Kumar Dubey ◽

Andleeb Zehra ◽

Mukesh Meena ◽

Ram Sanmukh Upadhyay

Keyword(s):

Fungal Infections ◽

Uttar Pradesh ◽

Economic Losses ◽

Dioecious Species ◽

The Past ◽

Achlya Ambisexualis ◽

Water And Soil Samples ◽

Dead Fish ◽

Rare Fish ◽

First Time

Achlya spp. are oomycetous water moulds, responsible for freshwater fish diseases causing great economic losses. An Achlya sp. implicated in significant fungal infections of both live and dead fish as well as their eggs, has been isolated from the water and soil samples collected from Chandraprabha dam (Chandauli District, Uttar Pradesh, India) employing standard baiting method. Based on morphological characterisation, the strain was identified as Achlya ambisexualis Raper 1939 (Saprolegniales, Oomycetes). It is a dioecious species, characterised by the presence of an achlyoid type of spore dehiscence from both primary and secondary sporangia, differentiated by its oospheres predominantly maturing into eccentric oospores, generally 1-18 per oogonium and gemmae cylindrical in both antheridial and oogonial mycelia. In India, this species was recorded from a single collection in the past but lack proper description and illustrations. The present study describes and illustrates this species for the first time in India and hoped to be beneficial for ichthyopathologists and researchers as A. ambisexualis is known as a necrotroph or parasite of fishes and their eggs.

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Prevalence of Dermatophytosis in Badaun, Uttar Pradesh, India

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2020/v32i3330951 ◽

2020 ◽

pp. 71-76

Author(s):

Pankaj Saxena ◽

Neeraj Dholia

Keyword(s):

Fungal Infection ◽

Fungal Infections ◽

Uttar Pradesh ◽

Age Group ◽

Tropical Countries ◽

Group 16 ◽

Diagnostic Centre

Dermatophytoses is a superficial fungal infection of tissues having keratin. The responsible fugus are dermatophytes. The infection is usually designated as ring worm or “tinea”. It is observed worldwide with higher prevalence in tropical countries and areas due to high rates of humidity, moisture and high sweating in summer. Recurrent dermatophytosis is a challenge for dermatologists in India and constituted 9.3% of all patients of dermatophytosis. The present study is conducted to reveal the prevalence of dermatophytosis in patients attended in the Maheshwari Hospital and Diagnostic Centre in Badaun. A survey was done for a period of one and half year. The samlples were obtained from Maheshwari Hospital and Diagnostic Centre, Badaun, Uttar Pradesh. A total of 300 patients were included in the study. Physical observation, KOH test, Microscopy and culture tests were performed for screening and confirmation of various fungal infections. Clinically the prevalence of dermatophytosis was 60% that was observed more in males. Patients with age group 16–30 and 31–40 years were more affected.

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