scholarly journals Global Pandemic COVID-19 (2019-nCoV): Novel Deadliest Contagion

Author(s):  
Mahnoor Patel

Global pandemic cause by coronavirus has been reported in Wuhan, China; in late December 2019. Within time duration of few weeks, the newly identified virus designated as 2019-Novel Coronavirus (2019-nCoV) and it was declared by World Health Organization (WHO). At the time of late January 2020, WHO announced it as the international emergency outbreak because of the rapid spread and increases at the global level. There is no any preventive vaccine is present or any approved therapy/treatment for this viral emergency which is very infectious globally. Till the previous few decades, six strains of coronaviruses were found, but in Wuhan, China in December 2019, a totally new strain of coronavirus was spread across the city. Within few days, it was designated as the novel coronavirus abbreviated as 2019-nCoV by World Health Organization. The rate of virus progression is still not determined and that is why it is very difficult to find the patient zero which is very essential. Phylogenetic analysis of the virus specifies bat origin of 2019-nCoV, its transmission is airborne i.e. human to human, infected person can be identified having the primary symptoms which includes high fever, upper or lower respiratory tract infection. Its diagnosis at the molecular level includes Real-Time PCR for encoding genes for the internal transcribed RNA-dependent RNA polymerase and Spike protein receptor binding domain. It can be confirmed by the Sanger Sequencing including full genome analysis by Next Generation Sequencing, multiplex nucleic acid amplification and microarray based analysis. There are few mRNA vaccines which were developed by few Biotechnology companies, showing positive results against COVID-19 and it is there in 4th phase clinical trial which possibly be the first vaccine available in the market in between mid-2021.

2021 ◽  
Vol 58 (3) ◽  
pp. 3444-3456
Author(s):  
Mr J Dorasamy, Et. al.

The World Health Organization (Who) In March 2020 Declared Covid 19 A Pandemic, Due To The  Global And Rapid Spread Of A Novel Coronavirus (Who, 2020). The Covid 19 Pandemic Being Highly Infectious And Unpredictable, Has  Disrupted  Social, Economic, Environmental And Political Spheres Of Life. Globally, People Have Ventured Into A “Lockdown World”, Increasing Uncertainty About Their Future Amidst The Covid 19 Pandemic. As A Result Of The Pandemic, Social Alteration Has Taken The Form Of Social Distancing, Self-Isolation And Self-Quarantine.  Many Were Unprepared For The Shift From The “Normal”, Propelling  Undue  Stress Under The New Normal Way Of Doing Things During The Current Global Pandemic Crisis. This Has Been Accompanied By Social, Emotional And Mental Effects, As The Ongoing And Fluid Nature Of The Pandemic Has Created Uncertainty For Many People. The Covid 19 Pandemic, As A Multidimensional Stressor Affecting Wellbeing, Has Affected Individuals, Families, Educational, Occupational, And Broader Societal Systems.  


Author(s):  
Mostafa Al-Emran

A novel coronavirus (COVID-19) has been identified in Wuhan, China, in late 2019 (Zhu et al., 2020). On March 11, 2020, the World Health Organization (WHO) has declared the outbreak of COVID-19 as a global pandemic (Cucinotta & Vanelli, 2020). In responding to this pandemic, a series of precautionary measures have been taken forward on a global basis to combat the spread of the virus. One of such measures was the lockdown of educational institutions. To compromise between the delivery of learning to students and committing to social distancing, the transition to distance learning was the unavoidable option in such crises.


Author(s):  
Ghotekar D S ◽  
Vishal N Kushare ◽  
Sagar V Ghotekar

Coronaviruses are a family of viruses that cause illness such as respiratory diseases or gastrointestinal diseases. Respiratory diseases can range from the common cold to more severe diseases. A novel coronavirus outbreak was first documented in Wuhan, Hubei Province, China in December 2019. The World Health Organization (WHO) has declared the coronavirus disease 2019 (COVID-19) a pandemic. A global coordinated effort is needed to stop the further spread of the virus. A novel coronavirus (nCoV) is a new strain that has not been identified in humans previously. Once scientists determine exactly what coronavirus it is, they give it a name (as in the case of COVID-19, the virus causing it is SARS-CoV-2).


Author(s):  
Lara Bittmann

On December 31, 2019, WHO was informed of cases of pneumonia of unknown cause in Wuhan City, China. A novel coronavirus was identified as the cause by Chinese authorities on January 7, 2020 and was provisionally named "2019-nCoV". This new Coronavirus causes a clinical picture which has received now the name COVID-19. The virus has spread subsequently worldwide and was explained on the 11th of March, 2020 by the World Health Organization to the pandemic.


2020 ◽  
Author(s):  
Mujib Ullah

UNSTRUCTURED Coronaviruses belong to a large family of viruses. Coronavirus also called COVID-19 is a new disease that has not been previously identified in humans. The World Health Organization has announced that COVID-19 is a pandemic. Currently there is no specific vaccine or treatment for COVID-19. Current treatment for COVID-19 is only supportive (treating the symptoms). There are no antiviral or vaccine options at this time. Therefore, it is time to bring collective efforts to treat or prevent a rapidly evolving pandemic of COVID-19.


Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1145
Author(s):  
Hakimeh Baghaei Daemi ◽  
Muhammad Fakhar-e-Alam Kulyar ◽  
Xinlin He ◽  
Chengfei Li ◽  
Morteza Karimpour ◽  
...  

Influenza is a highly known contagious viral infection that has been responsible for the death of many people in history with pandemics. These pandemics have been occurring every 10 to 30 years in the last century. The most recent global pandemic prior to COVID-19 was the 2009 influenza A (H1N1) pandemic. A decade ago, the H1N1 virus caused 12,500 deaths in just 19 months globally. Now, again, the world has been challenged with another pandemic. Since December 2019, the first case of a novel coronavirus (COVID-19) infection was detected in Wuhan. This infection has risen rapidly throughout the world; even the World Health Organization (WHO) announced COVID-19 as a worldwide emergency to ensure human health and public safety. This review article aims to discuss important issues relating to COVID-19, including clinical, epidemiological, and pathological features of COVID-19 and recent progress in diagnosis and treatment approaches for the COVID-19 infection. We also highlight key similarities and differences between COVID-19 and influenza A to ensure the theoretical and practical details of COVID-19.


2020 ◽  
Vol 30 (1) ◽  
pp. 38030 ◽  
Author(s):  
Deivendran Kalirathinam ◽  
Raj Guruchandran ◽  
Prabhakar Subramani

The 2019 novel coronavirus officially named as coronavirus disease 2019 (COVID-19) pandemic by the World Health Organization, has spread to more than 180 countries. The ongoing global pandemic of severe acute respiratory syndrome coronavirus, which causes COVID-19, spread to the United Kingdom (UK) in January 2020. Transmission within the UK was confirmed in February, leading to an epidemic with a rapid increase in cases in March. As on April 25- 2020, there have been 148,377 confirmed cases of COVID-19 in the UK and 20,319 people with confirmed infection have died. Survival of critically ill patients is frequently associated with significant functional impairment and reduced health-related quality of life. Early physiotherapy and community rehabilitation of COVID-19 patients has recently been identified as an essential therapeutic tool and has become a crucial evidence-based component in the management of these patients. This comprehensive narrative review aims to describe recent progress in the application of physiotherapy management in COVID 19 patients. Assessment and evidence- based treatment of these patients should include prevention, reduction of adverse consequences in immobilization, and long-term impairment sequelae. A variety of techniques and modalities of early physiotherapy in intensive care unit are suggested by clinical research. They should be applied according to the stage of the disease, comorbidities, and patient’s level of cooperation.


RSC Advances ◽  
2020 ◽  
Vol 10 (62) ◽  
pp. 38128-38141
Author(s):  
Sherif S. Ebada ◽  
Nariman A. Al-Jawabri ◽  
Fadia S. Youssef ◽  
Dina H. El-Kashef ◽  
Tim-Oliver Knedel ◽  
...  

On Wednesday 11th March, 2020, the world health organization (WHO) announced novel coronavirus (COVID-19, also called SARS-CoV-2) as a pandemic.


Author(s):  
Jeremy Smelt ◽  
Gowthanan Santhirakumaran ◽  
Paul Vaughan ◽  
Ian Hunt ◽  
Carol Tan

Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus primarily affecting the respiratory system, was initially diagnosed in Wuhan, China, in late 2019. Identified as coronavirus disease 2019 (COVID-19) by the World Health Organization, the virus rapidly became a global pandemic. The effects on health care worldwide were unprecedented as countries adapted services to treat masses of critically ill patients.The aim of this study is to analyze the effect that the COVID-19 pandemic had on thoracic surgery at a major trauma center during peak prevalence. Methods Prospective unit data were collected for all patients who underwent thoracic surgery during March 2020 until May 2020 inclusive. Retrospective data were collected from an earlier comparable time period as a comparison. Results In the aforementioned time frame, 117 thoracic surgical operations were performed under the care of four thoracic surgeons. Six operations were performed on three patients who were being treated for SARS-CoV-2. One operation was performed on a patient who had recovered from SARS-CoV-2. There were no deaths due to SARS-CoV-2 in any patient undergoing thoracic surgery. Conclusion This study demonstrates that during the first surge of SARS-CoV-2, it was possible to adapt a thoracic oncology and trauma service without increase in mortality due to COVID-19. This was only possible due to a significant reduction in trauma referrals, cessation of benign and elective work, and the more stringent reprioritization of cancer surgery. This information is vital to learn from our experience and prepare for the predicted second surge and any similar future pandemics we might face.


Author(s):  
Sholly. CK

Novel corona virus (COVID-19) is an infectious condition, which can be spread directly or indirectly from one person to another and causes respiratory illnesses, range from common cold to acute respiratory syndrome. The first cases of this virus were found in Wuhan, China. According to the World Health Organization, COVID-19 is serious health concern and has higher risk for severe illness and spreading rapidly all over the world.This novel coronavirus was named Coronavirus Disease 2019 (COVID-19) by WHO in February 2020. The World Health Organization (WHO) has declared the coronavirus disease 2019 a pandemic, in the year2020 March. A global coordinated effort is needed to stop the further spread of the virus. Among all cases about 92% of the confirmed cases were recorded from China. Initial reports suggest that death rate ranges from 1% to 2% which varies in the study and country. The most of the death have occurred in patients over 50 years of age followed by young children. For the confirmed cases which included both laboratory and clinically diagnosed till now there is no specific antiviral treatment recommended but there is vaccine currently available. Once the virus develops in people, corona viruses can be spread from person to person through respiratory droplets. The viral material hangs out in these droplets and can be breathed into the respiratory tract, where the virus can then lead to an infection. Repercussions of Covid -19 on individuals, families and on front line warriors are countless1.


Sign in / Sign up

Export Citation Format

Share Document