Iodine deficiency diseases in children and adolescents (plenary lecture)

2019 ◽  
Vol 43 (3) ◽  
pp. 3-7 ◽  
Author(s):  
E. P. Kasatkina
Keyword(s):  
Thyroid Gland ◽  
Adverse Effects ◽  
Children And Adolescents ◽  
Human Health ◽  
Iodine Deficiency ◽  
Functional Activity ◽  
Endemic Goiter ◽  
Plenary Lecture ◽  
Long Time ◽  
Deficiency Diseases

The main consequence of iodine deficiency in the environment is the development of goiter in people living in iodine-deficient regions (endemic goiter). In this regard, for a long time it was considered that goiter is the only manifestation of this condition. It has now been proven that, in addition to goiter, iodine deficiency also has other adverse effects on human health. In 1983, the term "endemic goiter" was replaced by the term  "iodine deficiency diseases" (IDD). These diseases are caused by a decrease in the functional activity of the thyroid gland in response to iodine deficiency.

scholarly journals Radiation-induced pathomorphism of endemic goiter in children and adolescents in a focus of iodine deficiency (initial manifestations of remore effects of the Chernobyl accident)

1995 ◽  
Vol 41 (3) ◽  
pp. 17-23 ◽  
Author(s):  
E. P. Kasatkina ◽  
D. Ye. Shilin ◽  
A. N. Matkovskaya ◽  
K N. Sokolovskaya ◽  
T. N. Volkova ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Iodine Deficiency ◽  
Chernobyl Accident ◽  
Radiation Effects ◽  
Low Dose ◽  
Endemic Goiter ◽  
Morphological Characteristics ◽  
Increased Risk ◽  
Diffuse Goiter ◽  
Progressive Growth

The formation of remote consequences of radiation effects on the thyroid status of the population exposed to low-dose radiation was studied. The authors analyzed epidemiological, clinical, biochemical, hormonal, ultrasonographic, immunological, and morphological characteristics of the prevalence and intensity of endemic goiter in children and adolescents living in two iodine-deficient districts of the Oryol region observed after contamination of their territory with 137-Cs in a dose of 1 to 5 Ci/km2 and in-corporation of 131-I in a dose of 20-30 rad and in a control district free from radiation contamination. The results indicate that under the effect of low-dose combined irradiation endemic goiter in the observed districts acquired atypical features in the six years that passed since the Chernobyl accident in comparison with that in the control region: 1) thyromegalia prevalence is increased, its level being disproportionate with the degree of the existent iodine deficiency; 2) sex-specific differences are completely absent; 3) the maximal strain is observed in children exposed to radioactive iodine in utero 4) morphologically, variants of diffuse goiter with a high risk of node formation predominate; 5) progressive growth of thyroid parenchyma is associated with increased thyroglobulin elimination, this increasing the strain of the humoral component of antithyroid autoimmunity. These data indicate that the modifying effect of low-dose exposure on endemic goiter resulted in the disease pathomorphism associated with oncological risk and increased risk of autoimmune thyroiditis.

scholarly journals Condition of lipid metabolism at women of genesial period and its correlation with functional activity of thyroid gland and ovary

2002 ◽  
Vol 1 (4) ◽  
pp. 110-113
Author(s):  
V. I. Korchin ◽  
E. V. Korneeva
Keyword(s):  
Lipid Metabolism ◽  
Thyroid Gland ◽  
Functional Status ◽  
Functional Activity ◽  
Far North ◽  
Long Time

In the present work all possible correlations between functional status of thyroid gland, ovaries and lipids of Serum of blood at women of genesial period living in Far North for a long time are investigated. In the process of investigation there was indentified that women with cyst of ovary have a rise of general cholesterol and cholesterol of lypoproteid of low solidity.

scholarly journals Genetic factors in the pathogenesis of iodine deficiency goiter

2004 ◽  
Vol 50 (1) ◽  
pp. 51-55
Author(s):  
V. V. Fadeev ◽  
N. A. Abramova
Keyword(s):  
Mental Retardation ◽  
Thyroid Gland ◽  
Iodine Deficiency ◽  
Genetic Factors ◽  
Severe Mental Retardation ◽  
The Earth ◽  
Human Pathology ◽  
Deficiency Diseases

Iodine deficiency diseases (IDD) are the most common non-infectious human pathology. In general, 1.5 billion people live on the Earth in regions of iodine deficiency in the environment, 600 million of them have an increase in the thyroid gland, and 40 million have severe mental retardation as a result of iodine deficiency

Impairment of neuromotor and cognitive development in iodine-deficient schoolchildren with normal physical growth

1993 ◽  
Vol 129 (6) ◽  
pp. 501-504 ◽  
Author(s):  
F Azizi ◽  
A Sarshar ◽  
M Nafarabadi ◽  
A Ghazi ◽  
M Kimiagar ◽  
...  
Keyword(s):  
Cognitive Development ◽  
Children And Adolescents ◽  
Thyroid Function ◽  
Iodine Deficiency ◽  
Endemic Goiter ◽  
Physical Growth ◽  
Psychomotor Development ◽  
Somatic Development ◽  
Intellectual Quotient ◽  
The Mean

In order to detect somatic and psychomotor disturbances in children and adolescents residing in areas of iodine deficiency, schoolchildren from three areas with different degrees of iodine deficiency were studied. In Randan, the prevalence of severe endemic goiter was accompanied by alteration in thyroid function, increased thyrotropin levels and retardation of both bone and psychomotor age and decreased intellectual quotient. In Tehran, where iodine deficiency is mild, visible goiter was present in 1 5% of schoolchildren but no alterations in thyroid function, serum thyrotropin, somatic or psychomotor development could be detected. In Zagoon, where the prevalence and severity of goiter was less than Randan but more than Tehran, thyroid function was normal but slightly decreased as compared to Tehran; somatic development was unaltered, but retardation in psychomotor development was evident and the mean intellectual quotient was less than that of Tehranian schoolchildren. These findings indicate the occurrence of physical and psychomotor disturbances in apparently normal schoolchildren from areas of iodine deficiency. Alteration in psychomotor development may occur in children with normal physical growth, due to iodine deficiency.

scholarly journals CORRECTION OF IODINE DEFICIENCY STATES AND DYNAMIC MODELING OF POSITIVE DYNAMICS OF INDICATORS OF THYROID FUNCTIONS BY SUPPLEMENTATION

2018 ◽  
Vol 2 ◽  
pp. 17-23
Author(s):  
Olesya Horlenko ◽  
Lubov Pushkash ◽  
Oleg Devinyak ◽  
Ivan Pushkash
Keyword(s):  
Thyroid Gland ◽  
Iodine Deficiency ◽  
Preventive Measures ◽  
Initial Level ◽  
Age Groups ◽  
Clinical Manifestations ◽  
Detailed Examination ◽  
Wide Range ◽  
Deficiency Diseases ◽  
Marked Tendency

The problem of iodine deficiency diseases (IDD) is recognized as relevant due to the significant prevalence of iodine deficiency among the population of many countries of the world, an increase in the incidence of diseases with a wide range of clinical manifestations and a marked tendency to increase the frequency and severity of IDD among children of all age groups We carried out a clinical-anamnestic examination of the child's contingent (187 persons) aged 13–17 years living in an ecologically dependent biogeochemical endemic zone of iodine deficiency, the mountain region of the Zakarpattya region during the period from 2014 to 2015. To identify the pathology of the thyroid gland, a palpatory method of examination was used according to the methodology of the WHO / MRKIDZ, 2001. According to our data 80 pupils (42.8 %) had increased thyroid gland of 1 degree, they were allocated for further and detailed examination and identification of environmentally caused somatic effects. Preventive measures included taking the dietary supplement Yosen, the manufacturer of TOV “OmniFarm”, TU U 10.8-35758392-004: 2014 for 6 months. A statistical model for forecasting the dynamics of TSH with supplements with iodine and selenium has been developed. According to our data, the degree of positive changes (decrease of TSH, increase of T4) with supplements with iodine and selenium depends on the starting content of the microelement of iodine in plasma and / or urine: the lower is the initial level of iodine - the more pronounced is the effect of supplements.

scholarly journals Frequency of endemic goiter and indicators of pituitary-thyroid profile in Arctic children

2021 ◽  
Vol 38 (4) ◽  
pp. 18-24
Author(s):  
S. A. Evseeva ◽  
T. E. Burtseva ◽  
T. M. Klimova ◽  
N. A. Danilov ◽  
V. G. Chasnyk ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Children And Adolescents ◽  
Preventive Measures ◽  
Endemic Goiter ◽  
Thyroid Stimulating Hormone ◽  
Free Thyroxine ◽  
The Arctic ◽  
Population Groups ◽  
Arctic Regions ◽  
Thyroid Profile

Objective. Analysis of the frequency of endemic goiter and indicators of the pituitary-thyroid profile in children aged 10-18 years living in the Arctic regions of Yakutia. Materials and methods. The study was conducted among children and adolescents of the Arctic regions of Yakutia (Bulunsky, Anabarsky, Allaikhovsky, Nizhnekolymsky, Verkhnekolymsky district) during field medical expeditions in 20182020. A total of 392 children aged 1018 years were examined. Results. In 30 % of the examined children, an increase in the thyroid gland was observed, which was accompanied by elevated levels of free thyroxine. In 3 % of children, an increase in the level of thyroid-stimulating hormone was detected against the background of reduced or normal levels of free thyroxine. Conclusions. As for the prevalence of cases of endemic goiter, the Arctic regions of Yakutia are the areas of severe goiter endemia. The results obtained justify the need for additional scientific studies to assess the degree of iodine availability (by the concentration of iodine in the urine) in different population groups and real implementation of the strategy of mass preventive measures.

Understanding Chemicals in Products

2020 ◽  
Vol 42 (3) ◽  
pp. 25-25
Keyword(s):  
Adverse Effects ◽  
Best Practices ◽  
Human Health ◽  
Building Materials ◽  
Global Environment ◽  
Global Environment Facility ◽  
Policy Issues ◽  
Strategic Approach ◽  
Chemicals Management ◽  
Funded Project

Abstract The Strategic Approach to International Chemicals Management (SAICM) has published a policy brief that addresses chemicals of concern in products such as textiles, toys, building materials, and electronics, and efforts to minimize their adverse effects on human health and the environment. The policy brief titled, “Understanding Chemicals in Products,” is a contribution from the Global Environment Facility (GEF)-funded project on “Global Best Practices on Emerging Chemical Policy Issues of Concern under SAICM.”

scholarly journals Special Issue Sources and Composition of Ambient Particulate Matter

Atmosphere ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 462
Author(s):  
Manousos-Ioannis Manousakas
Keyword(s):  
Particulate Matter ◽  
Adverse Effects ◽  
Human Health ◽  
Ambient Particulate Matter ◽  
Special Issue

Research related to ambient particulate matter (PM) remains very relative today due to the adverse effects PM have on human health. [...]

scholarly journals Achalasia Cardia: A Mimicker of Pulmonary Tuberculosis in a High-Burden Setting

2020 ◽  
Author(s):  
Pratibha Sharma ◽  
Ranganath T. Ganga
Keyword(s):  
South Africa ◽  
Adverse Effects ◽  
Respiratory Symptoms ◽  
Antitubercular Drugs ◽  
Achalasia Cardia ◽  
High Burden ◽  
Antitubercular Treatment ◽  
Common Diagnosis ◽  
National Tuberculosis ◽  
Long Time

AbstractBRICS (Brazil, Russia, India, China, and South Africa) countries account for more than two-thirds of the global tuberculosis burden. Tuberculosis is a common diagnosis in patients presenting with chronic respiratory symptoms in these high-burden countries, which results in other diseases being missed easily. The national tuberculosis elimination program encourages to start antitubercular treatment on a clinical basis even without any confirmatory evidence. This has resulted in missing many nontuberculosis cases and unnecessarily exposing to adverse effects of antitubercular drugs. Here we report one such instance where achalasia cardia was missed for a long time.

Sign in / Sign up

Export Citation Format

Share Document