Synthesis of nicotinamide-imprinted polymers and their binding performances in organic and aqueous media

e-Polymers ◽  
2008 ◽  
Vol 8 (1) ◽  
Author(s):  
Pattarawarapan Mookda ◽  
Komkham Singha ◽  
Kareuhanon Weeranuch ◽  
Tayapiwatana Chatchai
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Binding Capacity ◽  
Aqueous Media ◽  
Bulk Polymerization ◽  
Molar Ratio ◽  
Imprinted Polymer ◽  
Isolation And Identification ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Imprinted Polymers

AbstractTo obtain molecularly imprinted polymers capable of selective rebinding with nicotinamide (NAM), NAM imprinted polymers were synthesized via bulk polymerization using various functional monomers and cross-linkers. The NAM recognition properties of these polymers were investigated in organic and aqueous solvents by equilibrium rebinding experiments. The results show that the imprinted polymer prepared using 1:4:4 molar ratio of NAM/MAA/TRIM in dichloromethane exhibited the greatest NAM binding capacity and selectivity. This polymer is potentially valuable for the analysis of NAM in complex matrices where selective isolation and identification are needed.

scholarly journals Membrane Emulsification Process as a Method for Obtaining Molecularly Imprinted Polymers

Polymers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 2830
Author(s):  
Joanna Wolska ◽  
Nasim Jalilnejad Falizi
Keyword(s):  
Molecularly Imprinted Polymer ◽  
Molecularly Imprinted Polymers ◽  
Binding Capacity ◽  
Aqueous Media ◽  
Sorption Process ◽  
Imprinted Polymer ◽  
Membrane Emulsification ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Emulsification Process

The membrane emulsification process (ME) using a metallic membrane was the first stage for preparing a spherical and monodisperse thermoresponsive molecularly imprinted polymer (TSMIP). In the second step of the preparation, after the ME process, the emulsion of monomers was then polymerized. Additionally, the synthesized TSMIP was fabricated using as a functional monomer N-isopropylacrylamide, which is thermosensitive. This special type of polymer was obtained for the recognition and determination of trace bisphenol A (BPA) in aqueous media. Two types of molecularly imprinted polymers (MIPs) were synthesized using amounts of BPA of 5 wt.% (MIP-2) and 7 wt.% (MIP-1) in the reaction mixtures. Additionally, a non-imprinted polymer (NIP) was also synthesized. Polymer MIP-2 showed thermocontrolled recognition for imprinted molecules and a higher binding capacity than its corresponding non-imprinted polymer and higher than other molecularly imprinted polymer (MIP-1). The best condition for the sorption process was at a temperature of 35 °C, that is, at a temperature close to the phase transition value for poly(N-isopropylacrylamide). Under these conditions, the highest levels of BPA removal from water were achieved and the highest adsorption capacity of MIP-2 was about 0.5 mmol g−1 (about 114.1 mg g−1) and was approximately 20% higher than for MIP-1 and NIP. It was also observed that during the kinetic studies, under these temperature conditions, MIP-2 sorbed BPA faster and with greater efficiency than its non-imprinted analogue.

Water-compatible surface molecularly imprinted polymers with synergy of bi-functional monomers for enhanced selective adsorption of bisphenol A from aqueous solution

2016 ◽  
Vol 3 (1) ◽  
pp. 213-222 ◽  
Author(s):  
Feifei Duan ◽  
Chaoqiu Chen ◽  
Xiaofeng Zhao ◽  
Yongzhen Yang ◽  
Xuguang Liu ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Bisphenol A ◽  
Molecularly Imprinted Polymers ◽  
Selective Adsorption ◽  
Aqueous Media ◽  
Selective Removal ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Imprinted Polymers ◽  
Adsorption Performance

Water-compatible surface molecularly imprinted polymers were synthesized via bi-functional monomers and exhibited excellent adsorption performance for the selective removal of BPA from aqueous media.

scholarly journals Phthalocyanine-Based Molecularly Imprinted Polymers as Nucleoside Receptors

2008 ◽  
Vol 2008 ◽  
pp. 1-5 ◽  
Author(s):  
Luigia Longo ◽  
Giuseppe Vasapollo
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Binding Capacity ◽  
Zinc Phthalocyanine ◽  
Scatchard Analysis ◽  
Binding Affinities ◽  
Imprinted Polymer ◽  
Binding Ability ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Combined Use

A molecularly imprinted polymer (MIP) for tri-O-acetyladenosine (TOAA), PPM(TOAA), was prepared by the combined use of methacrylic acid (MAA) and Zn(II)tetra(4'-methacryloxyphenoxy) phthalocyanine as functional monomers. This MIP exhibited a higher binding ability for TOAA compared to the MIP prepared using only MAA, PM(TOAA), in batch rebinding tests. Scatchard analysis gave a higher association constant of PPM(TOAA) for TOAA (2.96×104 M−1) than that of PM(TOAA) (1.48×104 M−1). The MIP prepared using only the zinc-phthalocyanine, PP(TOAA), did not show any binding capacity for TOAA. This means that the phthalocyanine in the MIP contributes to higher affinities, although it barely interacts with TOAA. Since selectivity for this kind of MIPs is more important than binding affinity, the binding of TOAA and a structurally related compound, tri-O-acetyluridine (TOAU), on the polymers was investigated. Both PPM(TOAA) and PM(TOAA) exhibited binding affinities for TOAA while they did not show any binding capacity for TOAU.

scholarly journals IDENTIFICATION OF DRIVING FORCES FOR THE RECOGNITION PROCESSES ON MOLECULARLY IMPRINTED POLYMERS

2013 ◽  
Vol 12 (2) ◽  
pp. 63-69 ◽  
Author(s):  
Natalia Denderz ◽  
Jozef Lehotay
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Driving Forces ◽  
Bulk Polymerization ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Imprinted Polymers ◽  
Retention Factors ◽  
Mobile Phases ◽  
Almost All ◽  
Derivatives Of

Abstract In this paper the thermodynamic analyses were used to calculate the contributions of entropic and enthalpic terms of the binding processes of selected derivatives of alkoxy-substituted phenylcarbamic acid (MEP) and phenolic acids (PAs) on the series of molecularly imprinted polymers (MIPs) and corresponding non-imprinted polymers (NIPs). All polymers were prepared by a bulk polymerization method with different porogens and functional monomers. The thermodynamic assessments were based on the quantification by HPLC measurements of the analytes tested in different mobile phases and at temperature range from 293 K to 333 K. The thermodynamic parameters were determined from the van’t Hoff plots - dependences between logarithms of the retention factors of studied analytes (ln k) and the inverse value of the temperature (1/T). Almost all data showed that enthalpic term was the dominating driving force for the investigated analytes.

scholarly journals Ferric Iron-Containing Molecularly Imprinted Polymer as an Adsorbent for Cholesterol

2003 ◽  
Vol 21 (3) ◽  
pp. 261-268 ◽  
Author(s):  
K. Sreenivasan ◽  
R. Sivakumar
Keyword(s):  
Adsorption Capacity ◽  
Molecular Imprinting ◽  
Molecularly Imprinted Polymer ◽  
Molecularly Imprinted Polymers ◽  
Ferric Iron ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Imprinted Polymers ◽  
Chemically Modified

Molecular imprinting is an elegant approach to the synthesis of polymers with predetermined recognition properties, the technique of molecular imprinting involving arranging the functional monomers around the print molecules prior to polymerisation. Molecularly imprinted polymers (MIPs) show a remarkable ability to bind print molecule from a mixture of entities which are close in structure. One of the serious drawbacks of MIPs is their low adsorption capacity and one approach to improving this relies on the use of chemically modified monomers in the synthesis of the MIPs. This report discusses the synthesis and evaluation of an MIP based on ferric acrylate as an adsorbent for cholesterol.

scholarly journals Hydrophilic molecularly imprinted polymers for selective recognition of polycyclic aromatic hydrocarbons in aqueous media

RSC Advances ◽  
2015 ◽  
Vol 5 (4) ◽  
pp. 2659-2662 ◽  
Author(s):  
Wenchao Wei ◽  
Rongning Liang ◽  
Zhuo Wang ◽  
Wei Qin
Keyword(s):  
Aqueous Solution ◽  
Aromatic Hydrocarbons ◽  
Molecularly Imprinted Polymers ◽  
Aqueous Media ◽  
Selective Recognition ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Polycyclic Aromatic ◽  
Hydrophilic Molecularly Imprinted Polymers

A hydrophilic molecularly imprinted polymer (H-MIP) for phenanthrene has been synthesized with higher selectivity in aqueous solution than the traditional MIP.

scholarly journals Examination of the Chemical Composition of Propolis IX. Solid Phase Extraction of Coumarins from Propolis by Using Molecularly Imprinted Polymer

2013 ◽  
Vol 12 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Katarína Hroboňová ◽  
Jozef Lehotay ◽  
Jozef Čižmárik
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Hplc Analysis ◽  
Chromatographic Method ◽  
Solid Phase ◽  
Binding Capacity ◽  
Bulk Polymerization ◽  
Template Molecule ◽  
Synthetic Method ◽  
Imprinted Polymer ◽  
Molecularly Imprinted

Abstract The group selective molecularly imprinted polymers (MIPs) for coumarins, including umbelliferone, herniarin, 4-methylumbelliferone, scoparone were developed. Using umbelliferone as the template molecule, methacrylic acid as functional monomer, ethylene glycol dimethacrylate as linking agent, chloroform as porogen and bulk polymerization as synthetic method, the MIPs were synthesized and characterized with rebinding experiments. The characteristics of MIPs were evaluated by chromatographic method and frontal analysis, and demonstrating good selectivity and high binding capacity (269 μg of umbelliferone per 100 mg of polymer). The group selective MIP was used as sorbent for the SPE pretreatment of coumarins from propolis extracts prior to HPLC analysis. Analysis of the samples showed good recoveries (>70 %). The limits of quantitation (LOQs) for studied compounds were 0.3-10 ng.mL-1 (determined for fluorescence detection).

Application of umbelliferone molecularly imprinted polymer in analysis of plant samples

2013 ◽  
Vol 67 (5) ◽  
Author(s):  
Katarína Hroboňová ◽  
Andrea Spevak ◽  
Ľubica Spišská ◽  
Jozef Lehotay ◽  
Jozef Čižmárik
Keyword(s):  
Molecularly Imprinted Polymers ◽  
High Performance ◽  
Limit Of Detection ◽  
Binding Capacity ◽  
Specific Binding ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Limit Of Determination ◽  
Pre Treatment

AbstractThe molecularly imprinted polymers (MIPs) were synthesised and the influence of the type of porogen, the nature of sample solvent, and the binding capacity of material were tested by high-performance liquid chromatography (HPLC). Umbelliferone was used as the template for imprint formation. Methacrylic acid was used as the monomer and acetonitrile, ethanol, and chloroform as porogen. Non-imprinted polymers (NIPs) were prepared by the same procedure. The highest value of the specific binding capacity (269 μg of umbelliferone per 100 mg of polymer) was obtained for polymers prepared in chloroform as porogen and methanol/water (φ r = 1: 1) as the sample solvent. The group-selective MIP was used as sorbent for the SPE pre-treatment of umbelliferone from plant extracts prior to HPLC analysis. Analysis of the spiked samples showed good recoveries (> 77 %). The limit of detection, limit of determination, and repeatability of the method were also calculated.

scholarly journals Rational Design of Molecularly Imprinted Polymers Using Quaternary Ammonium Cations for Glyphosate Detection

Sensors ◽  
2021 ◽  
Vol 21 (1) ◽  
pp. 296
Author(s):  
Mashaalah Zarejousheghani ◽  
Alaa Jaafar ◽  
Hendrik Wollmerstaedt ◽  
Parvaneh Rahimi ◽  
Helko Borsdorf ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Quaternary Ammonium ◽  
Photoelectron Spectroscopy ◽  
Rational Design ◽  
Water Soluble ◽  
Trimethylammonium Chloride ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Imprinted Polymers ◽  
Quaternary Ammonium Cations

Molecularly imprinted polymers have emerged as cost-effective and rugged artificial selective sorbents for combination with different sensors. In this study, quaternary ammonium cations, as functional monomers, were systematically evaluated to design imprinted polymers for glyphosate as an important model compound for electrically charged and highly water-soluble chemical compounds. To this aim, a small pool of monomers were used including (3-acrylamidopropyl)trimethylammonium chloride, [2-(acryloyloxy)ethyl]trimethylammonium chloride, and diallyldimethylammonium chloride. The simultaneous interactions between three positively charged monomers and glyphosate were preliminary evaluated using statistical design of the experiment method. Afterwards, different polymers were synthesized at the gold surface of the quartz crystal microbalance sensor using optimized and not optimized glyphosate-monomers ratios. All synthesized polymers were characterized using atomic force microscopy, contact angle, Fourier-transform infrared, and X-ray photoelectron spectroscopy. Evaluated functional monomers showed promise as highly efficient functional monomers, when they are used together and at the optimized ratio, as predicted by the statistical method. Obtained results from the modified sensors were used to develop a simple model describing the binding characteristics at the surface of the different synthesized polymers. This model helps to develop new synthesis strategies for rational design of the highly selective imprinted polymers and to use as a sensing platform for water soluble and polar targets.

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