scholarly journals Effects of Probiotic Supplementation on Selected Parameters of Blood Prooxidant‐Antioxidant Balance in Elite Athletes: A Double‐Blind Randomized Placebo‐Controlled Study

2018 ◽  
Vol 64 (1) ◽  
pp. 111-122 ◽  
Author(s):  
Danica Michalickova ◽  
Jelena Kotur-Stevuljevic ◽  
Milica Miljkovic ◽  
Nenad Dikic ◽  
Marija Kostic-Vucicevic ◽  
...  

AbstractA randomized, double-blind, placebo-controlled study was conducted, in order to evaluate if Lactobacillus helveticus Lafti® L10 (Lallemand Health Solutions, Montreal, Canada) supplementation during three months could influence oxidative markers in the population of elite athletes: triathletes, cyclists and endurance athletes. Twenty-two elite athletes were randomized to either placebo (n = 12) or probiotic (n = 10) groups. The probiotic group received 2x1010 colony forming units of Lafti® L10. Before and after the supplementation serum samples were collected. Markers of oxidative stress and anti-oxidative defense: superoxide dismutase (SOD), paraoxonase (PON), advanced oxidation protein products (AOPP), malondialdehyde (MDA), total antioxidant status, total oxidant status, pro-oxidant-antioxidant balance, oxidative stress index, bilirubin, uric acid and albumin were determined in serum. Parameters of lipid status, as well as susceptibility to copper-induced oxidation of LDL particles in vitro were also determined. There was a significant interaction effect for MDA (p = 0.039), with a decrease in MDA in the probiotic group only (p = 0.049). There was a significant interaction effect for AOPP (p = 0.037), with a significant decrease in the probiotic group (p = 0.045). Interaction effect for SOD was approaching to formal significance (p = 0.108) and the post-hoc test showed a significant decrease in the probiotic group (p = 0.041) only. A significant correlation between AOPP and SOD (p = 0.012, r = -0.40) was found in the probiotic group at the end of the study. PON1 activity was decreased in both the probiotic (p = 0.032) and placebo group (p = 0.035). No significant changes in the remainder of the evaluated parameters were noted. In conclusion, probiotic strain Lafti® L10 exerts certain antioxidant potential, but further research is needed.

2016 ◽  
Vol 41 (7) ◽  
pp. 782-789 ◽  
Author(s):  
Danica Michalickova ◽  
Rajna Minic ◽  
Nenad Dikic ◽  
Marija Andjelkovic ◽  
Marija Kostic-Vucicevic ◽  
...  

A randomized, double-blind, placebo-controlled study was conducted to evaluate if Lactobacillus helveticus Lafti L10 (Lallemand Health Solutions, Montreal, Que., Canada) supplementation during 14 weeks in winter can influence the duration, severity, and incidence of upper respiratory tract illness (URTI), as well as to monitor different immune parameters in the population of elite athletes. Before and after the treatment, cardiopulmonary testing and self-rated state of moods evaluation (by Profile of Mood States questionnaire) were performed and blood samples were collected. Thirty-nine elite athletes were randomized either to the placebo (n = 19) or the probiotic (n = 20) group. The probiotic group received L. helveticus Lafti L10, 2 × 1010 Colony Forming Units. Lafti L10 significantly shortened the URTI episode duration (7.25 ± 2.90 vs. 10.64 ± 4.67 days, p = 0.047) and decreased the number of symptoms in the probiotic group (4.92 ± 1.96 vs. 6.91 ± 1.22, p = 0.035). Severity and incidence of URTI did not differ between the treatments. There were no significant changes in leukocyte subpopulation abundance, transforming growth factor-β serum levels, level of interleukin-10 secreted from peptidoglican stimulated peripheral blood mononuclear cells (PBMCs), interferon-γ level secreted from concanavalin A-stimulated PBMCs or viability/proliferation of PBMCs upon antigen stimulation. Group effect for CD4+/CD8+ ratio was significant (F[1,37] = 6.99, p = 0.020, η2 = 0.350); this difference was not significant at baseline, but was evident after 14 weeks (p = 0.02). A significant interaction effect was noted for self-rated sense of vigor (F[1,37] = 11.76, p = 0.009, η2 = 0.595). Self-rated sense of vigor increased in the probiotic group (18.5 ± 4.1 vs. 21.0 ± 2.6, p = 0.012). Probiotic strain Lafti L10 can be a beneficial nutritional supplement for the reduction of URTI length in elite athletes.


2001 ◽  
Vol 49 (3) ◽  
pp. 293-297
Author(s):  
S. O. Bakare ◽  
M. G. M. Kolo ◽  
J. A. Oladiran

There was a significant interaction effect between the variety and the sowing date for the number of productive tillers, indicating that the response to sowing date varied with the variety. A significant reduction in the number of productive tillers became evident when sowing was delayed till 26 June in the straggling variety as compared to sowing dates in May. Lower numbers of productive tillers were also recorded when the sowing of the erect variety was further delayed till 10 July. The grain yield data showed that it is not advisable to sow the straggling variety later than 12 June, while sowing may continue till about 26 June for the erect variety in the study area.


2019 ◽  
Vol 14 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Banin Maghfirotin Marta ◽  
Utami Tyas ◽  
Cahyanto Muhammad Nur ◽  
Widada Jaka ◽  
Rahayu Endang Sutriswati

Consumption of probiotics is known to influence the gut microbiota. The aim of this study was to assess the effect of probiotic powder containing Lactobacillus plantarum Dad-13 on bacterial composition in the gut by examining fecal samples of school-age children in Yogyakarta, Indonesia. This is a randomized, double-blind, placebo-controlled study. A total of 40 healthy subjects were recruited for this study and were divided into two groups: placebo group and probiotic group. The placebo group consumed skim milk and the probiotic group consumed probiotic powder containing L. plantarum Dad-13 (2 × 109 CFU/g) for 65 days. The results showed that placebo intake had no significant effect on gut microbiota; however, probiotic caused a significant increase in L. plantarum and Lactobacillus population, while decreasing the population of E. coli and non-E. coli coliform bacteria by 55% and 75%, respectively and Bifidobacteria count did not change significantly. The study concluded that consumption of probiotic powder L. plantarum Dad-13 could increase propionic acid thereby decreasing the gut pH which has an effect on the microbial population.


2004 ◽  
Vol 19 (8) ◽  
pp. 494-498 ◽  
Author(s):  
Laurence Claes ◽  
Walter Vandereycken ◽  
Hans Vertommen

AbstractObjective.– The family environment is known to be an important contributor to the course of psychiatric disorders. In this study, we examined the family context of eating disordered (ED) patients with and without self-injurious behaviors (SIB).Method.– A Dutch adaptation of the Family Environment Scale ‘Sci Eng 57(9-B):1997;5927’ was completed by 131 ED patients of whom 47% showed at least one form of SIB (e.g., cutting, burning, hair pulling, etc.).Results– Results showed a significant difference in family environment between patients with and without SIB. The family environment of self-injuring ED patients was less cohesive, expressive and socially oriented, and more conflictual and disorganized than the family environment of those without SIB. No significant differences in perceived family environment were found with respect to the number or form of SIB and the subtype of ED. Neither did we find a significant interaction effect between ED subtype and presence/absence of SIB.


Author(s):  
María Vicent ◽  
M. P. Aparicio Flores ◽  
Cándido J. Inglés ◽  
Mª Isabel Gómez-Núñez ◽  
Aitana Fernández-Sogorb ◽  
...  

Abstract. CHILD PERFECTIONISM: DIFFERENCES ACROSS SEX AND AGE The aim of this study was to analyze the sex and age differences in the levels of child perfectionism, considering the dimensions: Socially Prescribed Perfectionism (SPP), Self-Oriented Perfectionism Criticism (SOP-C) and Self-Oriented Perfectionism Strivings (SOP-S). The sample was composed by 804 Primary Education students from Spain, aged between 8 and 11 years old (Mage = 9.57; SD = 1.12). The Spanish version of the Child and Adolescent Perfectionism Scale was used to assess the perfectionist dimensions. The results of the variance analysis revealed statistically significant differences in favor of males for SOP-C and SOP-S dimensions. However, these differences had no practical relevance because their associated magnitude (d index) were below .20. Similarly, no statistically significant differences were observed across age for perfectionist dimensions. Moreover, a significant interaction effect (sex x age) was not found.Keywords: child perfectionism, sex, age, Child and Adolescent Perfectionism Scale, Primary Education.Resumen.El objetivo de este estudio consistió en analizar las diferencias en función del sexo y la edad en los niveles de perfeccionismo infantil, atendiendo a las dimensiones: Perfeccionismo Socialmente Prescrito (PSP), Perfeccionismo Auto-Orientado Críticas (PAO-C) y Perfeccionismo Auto-Orientado Esfuerzos (PAO-E). La muestra se compuso de 804 alumnos españoles de Educación Primaria con edades comprendidas entre 8 y 11 años (Medad = 9.57; SD = 1.12). Las dimensiones perfeccionistas fueron evaluadas a través de la versión española de la Child and Adolescent Perfectionism Scale. Los resultados del análisis de varianza revelaron diferencias estadísticamente significativas en favor de los varones para las dimensiones PAO-C y PAO-E. Sin embargo, dichas diferencias carecieron de relevancia práctica puesto que la magnitud asociada (índice d) fue inferior a .20. Similarmente, no se observaron diferencias estadísticamente significativas en función de la edad para ninguna de las dimensiones perfeccionistas ni se encontró un efecto de interacción (sexo x edad) significativo.Palabras clave: perfeccionismo infantil, sexo, edad, Child and Adolescent Perfectionism Scale, Educación Primaria


Author(s):  
Agus Ramdani

The objective of this research is to find out the effect of Personality (P) and knowledge students about ecosystem (KS) on environmental behaviour (EB). An expost facto method has been used by selecting 8 sample for each cell. Reliability of P was  .964, KS was .937 and EB was .95. Data analyzed by two-way ANOVA. Research results revealed that there was environmental behaviour significant difference between those students who have most extraversion personality compared to introversion personality. Moreover, there was significant interaction effect between personality and knowledge students about ecosystem on environmental behaviour. 


Games ◽  
2018 ◽  
Vol 9 (3) ◽  
pp. 72 ◽  
Author(s):  
Lorenzo Spadoni ◽  
Jan Potters

We investigate, theoretically and experimentally, the effect of competition on risk taking in a contest in which players only decide on the level of risk they wish to take. Taking more risk implies a chance of a higher performance, but also implies a higher chance of failure. We vary the level of competition in two ways: by varying the number of players (2 players versus 8 players), and by varying the sensitivity of the contest to differences in performance (lottery contest versus all-pay auction). Our results show that there is a significant interaction effect between the two treatments, suggesting that players are particularly prone to take more risks if both the number of players and the sensitivity to performance are higher.


2010 ◽  
Vol 20 (6) ◽  
pp. 496-506 ◽  
Author(s):  
Edith Filaire ◽  
Alain Massart ◽  
Hugues Portier ◽  
Matthieu Rouveix ◽  
Fatima Rosado ◽  
...  

The aim of this investigation was to assess the effects of 6 wk of eicosapentanoic acid (EPA) and docosahexanoic acid (DHA) supplementation on resting and exercise-induced lipid peroxidation and antioxidant status in judoists. Subjects were randomly assigned to receive a placebo or a capsule of polyunsaturated fatty acids (PUFAs; 600 mg EPA and 400 mg DHA). Blood samples were collected in preexercise and postexercise conditions (judo-training session), both before and after the supplementation period. The following parameters were analyzed: α-tocopherol, retinol, lag phase, maximum rate of oxidation (Rmax) during the propagating chain reaction, maximum amount of conjugated dienes (CDmax) accumulated after the propagation phase, nitric oxide (NO) and malondyaldehide (MDA) concentrations, salivary glutathione peroxidase activity, and the lipid profile. Dietary data were collected using a 7-day dietary record. A significant interaction effect between supplementation and time (p < .01) on triglycerides was noted, with values significantly lower in the n-3 long-chain-PUFA (LCPUFA) group after supplementation than in the placebo group. Significant interaction effects between supplementation and time on resting MDA concentrations and Rmax were found (p = .03 and p = .04, respectively), with elevated values in the n-3 LCPUFA group after supplementation and no change in the placebo group’s levels. The authors observed a significantly greater NO and oxidative-stress increase with exercise (MDA, Rmax, CDmax, and NO) in the n-3 LCPUFA group than with placebo. No main or interaction effects were found for retinol and α-tocopherol. These results indicate that supplementation with n-3 LCPUFAs significantly increased oxidative stress at rest and after a judo-training session.


2020 ◽  
Vol 78 (2) ◽  
pp. 573-585
Author(s):  
Hyemin Jang ◽  
Hee Jin Kim ◽  
Yeong Sim Choe ◽  
Soo-Jong Kim ◽  
Seongbeom Park ◽  
...  

Background: As Alzheimer’s disease (AD) and cerebral small vessel disease (CSVD) commonly coexist, the interaction between two has been of the considerable interest. Objective: We determined whether the association of Aβ and tau with cognitive decline differs by the presence of significant CSVD. Methods: We included 60 subcortical vascular cognitive impairment (SVCI) from Samsung Medical Center and 82 Alzheimer’s disease-related cognitive impairment (ADCI) from ADNI, who underwent Aβ (florbetaben or florbetapir) and tau (flortaucipir, FTP) PET imaging. They were retrospectively assessed for 5.0±3.9 and 5.6±1.9 years with Clinical Dementia Rating-sum of boxes (CDR-SB)/Mini-Mental State Examination (MMSE). Mixed effects models were used to investigate the interaction between Aβ/tau and group on CDR-SB/MMSE changes. Results: The frequency of Aβ positivity (45% versus 54.9%, p = 0.556) and mean global FTP SUVR (1.17±0.21 versus 1.16±0.17, p = 0.702) were not different between the two groups. We found a significant interaction effect of Aβ positivity and SVCI group on CDR-SB increase/MMSE decrease (p = 0.013/p < 0.001), and a significant interaction effect of global FTP uptake and SVCI group on CDR-SB increase/MMSE decrease (p < 0.001 and p = 0.030). Finally, the interaction effects of regional tau and group were prominent in the Braak III/IV (p = 0.001) and V/VI (p = 0.003) not in Braak I/II region (p = 0.398). Conclusion: The association between Aβ/tau and cognitive decline is stronger in SVCI than in ADCI. Therefore, our findings suggested that Aβ positivity or tau burden (particularly in the Braak III/IV or V/VI regions) and CSVD might synergistically affect cognitive decline.


Author(s):  
Hsiang-Ming Lee ◽  
Ya-Hui Hsu ◽  
Tsai Chen

The tobacco epidemic is one of the most serious public health issues in the world. Tobacco use starts and becomes established primarily during adolescence, and nearly 9 out of 10 cigarette smokers first tried smoking by age 18, with 99% first trying by age 26. This study employed a 2 (advertising appeal: emotional vs. rational) by 2 (self-referencing: analytical vs. narrative) factorial design in Study 1; and a 2 (relational-interdependent self-construal: high and low) by 3 (social relational cue: self, friend, and family) factorial design in Study 2. The behavior intention of anti-smoking acted as the measured dependent variable. Samples of 192 (Study 1) and 222 (Study 2) were collected from one of the biggest high schools in northern Taiwan. The results showed advertising appeal and self-referencing had a significant interaction effect on behavior intention (p = 0.040). The results also showed rational appealing advertising is suitable for analytical self-referencing (p = 0.022) and emotional appealing advertising is suitable for narrative self-referencing (p = 0.067). However, the social relationship cue and relational-interdependent self-construal had no significant interaction effect on behavior intention, and only relational-interdependent self-construal significantly affected behavior intention (p < 0.001). Regardless of whether the relational-interdependent self-construal is high or low, when the anti-smoking advertising is from the family perspective to persuade adolescents not to smoke, both influence the adolescent more than the other two social relationship cues (self and friend).


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