scholarly journals Original Article. Demographic Changes in the Population of Bulgaria as Challenges for Anaesthesiologists

2016 ◽  
Vol 9 (2) ◽  
pp. 130-133
Author(s):  
Vladimir R. Radev ◽  
Radko N. Radev ◽  
Daniela A. Arabadzhieva ◽  
Vladin I. Petrov ◽  
Nikolay H. Kolev
Keyword(s):  
Population Decline ◽  
University Hospital ◽  
Annual Number ◽  
Multidisciplinary Teams ◽  
The Past ◽  
Statistical Institute ◽  
Age Related ◽  
Physical Classification ◽  
The University ◽  
Organ Changes

Summary In the past two decades, the demographic crisis in Bulgaria has been widely debated. According to the National Statistical Institute (NSI), the proportion of people aged 65 and over is increasing, despite the general population decline in the country. To investigate whether the age structure of patients operated on has changed during the past 10 years and assess the need to reorganize the training of anesthetists,aretrospective study in the anesthesia electronic database of the University Hospital in Rouse was carried out. The data of anesthesia performed by anesthesiologists in 2005, 2010 and 2015 in patients aged 65 and over were summarized. The distribution of these patients by ASA Physical Classification System and frequency of complications during anesthesia were analyzed. The average annual number of anaesthesias for the three years was almost unchanged and amounted to about 5500. The proportion of patients aged 65 and over increased from 30.54%in 2005 to 35.72%in 2010, and 37.81%in 2015. The distribution of patients in according to the ASA Classification changed significantly: the percentage of patients ASAI-IIdropped from 36.19%in 2005 to 11.85%in 2015. The patients in the ASA III-IVgroups for the three analyzed years was 41.86%, 58.66%and 65.30%, respectively, and this was mainly due to the increase in the ASAIVpatients. It is necessary to build multidisciplinary teams and prepare specialized protocols for behavior in geriatric patients. It is imperative that anesthesiologists possess specialized knowledge about age-related organ changes and their effects on anesthesia.

scholarly journals COMEPA (COVID-19 Medicina Policlinico Palermo): a study in hospitalized patients

2021 ◽  
Vol 7 (3) ◽  
Author(s):  
The COMEPA group
Keyword(s):  
Internal Medicine ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Prognostic Factors ◽  
Clinical Practice ◽  
Medical Records ◽  
University Hospital ◽  
Efficacy And Safety ◽  
The Past ◽  
The University

Coronavirus disease 2019 (COVID-19) has dramatically changed our lives. In the past months, hospitals were saturated of patients; therefore, it is still important to have simple and standardized prognostic factors and to evaluate the efficacy and safety of medications commonly used for COVID-19. We aimed to collect data of the patients hospitalized in Internal Medicine and Geriatrics Wards at the University Hospital (Policlinico) ‘P. Giaccone’ in Palermo, Italy (COMEPA, COVID-19 Medicina Policlinico Palermo), with the main purpose of finding prognostic tools that can be easily used in clinical practice in order to identify patients hospitalized for/with COVID-19 at higher risk of negative outcomes, such as mortality, transfer to Intensive Care Unit (ICU) and institutionalization, as well as evaluating the efficacy/safety of medications commonly used for COVID-19. For reaching these aims, the medical records of approximately 600 patients will be recorded, having data on several parameters and including as outcomes mortality, ICU placement, institutionalization. With the COMEPA study, we therefore plan to update current literature, giving new data on prognostic factors and on the efficacy/safety of some medications used for COVID-19.

Time Perspective among Patients Diagnosed with Neurotic and Personality Disorders − an Exploratory, Clinical Study

2021 ◽  
pp. 1-20
Author(s):  
Joanna Mostowik ◽  
Krzysztof Rutkowski ◽  
Tadeusz Ostrowski ◽  
Michał Mielimąka
Keyword(s):  
General Population ◽  
Personality Disorders ◽  
Time Perspective ◽  
University Hospital ◽  
The Past ◽  
Behavioural Syndromes ◽  
Balanced Time Perspective ◽  
Icd 10 ◽  
The University ◽  
Distinct Features

Abstract (1) An assessment of the structure of time perspective (TP) in a group of patients with neurotic and personality disorders (ICD-10: F4x, F60.x, F61) treated with group psychotherapy. (2) An analysis of the differences between the structure of TP in patients and the general population in order to expand the understanding of the relations between TP and mental health. Data were collected from 49 patients at the University Hospital Day Centre for the Treatment of Neurotic Disorders and Behavioural Syndromes. The measurement of TP was performed with the Zimbardo Time Perspective Inventory. A licensed psychiatrist conducted the diagnosis of neurotic and personality disorders, with additional data obtained from the Symptom Checklist KO ‘O’ and the Neurotic Personality Questionnaire KON-2006. The statistical analysis revealed significant differences in the structure of TP between patients and the general population. Among patients, the intensity of the past experienced negatively was significantly higher, and subsequently, the degree of the past experienced positively was lower. Patients remain in the negative past and concentrate much more on the pain and the worrying memories. They give much less attention to what was and what is valuable and pleasant in their life. Results of this research reveal distinct features of the structure of TP in the studied group. Findings underline the clinical relevance of TP at various stages of therapy. Restoring a balanced time perspective could be regarded as a tenable goal for psychotherapy and perhaps an innovative indicator of the treatment’s effectiveness.

Epidemiology of Clostridium difficile infection: results of a hospital-based study in Krakow, Poland

2015 ◽  
Vol 143 (15) ◽  
pp. 3235-3243 ◽  
Author(s):  
J. CZEPIEL ◽  
J. KĘDZIERSKA ◽  
G. BIESIADA ◽  
M. BIRCZYŃSKA ◽  
W. PERUCKI ◽  
...  
Keyword(s):  
Clostridium Difficile ◽  
Fold Increase ◽  
Time Span ◽  
University Hospital ◽  
Posterior Stabilization ◽  
The Past ◽  
Risk Of Mortality ◽  
Crude Mortality ◽  
Medical Wards ◽  
The University

SUMMARYOver the past two decades Clostridium difficile infection (CDI) has appeared as a major public health threat. We performed a retrospective study based on the records of patients hospitalized for CDI at the University Hospital in Krakow, Poland, between 2008 and 2014. In the study period, CDI occurred in 1009 individuals. There were 790 (78%) individuals who developed infection only once, whereas 219 (22%) developed infection more than once. The percentage of deaths within 14 days of CDI confirmation was 2·4%, with a mean age of 74·2 ± 15·9 years. Crude mortality was 12·9% in medical wards, 5·6% for surgical wards and 27·7% in the ICU setting. The time span between diagnosis and death was 5·1 days on average. Between 2008 and 2012 a 6·5-fold increase of CDI frequency with a posterior stabilization and even reduction in 2013 and 2014 was observed. According to the data analysed, 2/3 patients in our population developed CDI during their hospitalization even though they were admitted for different reasons. Medical wards pose a significantly higher risk of CDI than the surgical ones. Age is a risk factor for CDI recurrence. In the case of patients who died, death occurred shortly after diagnosis. The first CDI episode poses much higher risk of mortality than the consecutive ones.

scholarly journals Lack of Evidence for an Association between Previous HEV Genotype-3 Exposure and Glomerulonephritis in General

Pathogens ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 18
Author(s):  
Sven Pischke ◽  
Sarah Tamanaei ◽  
Maria Mader ◽  
Julian Schulze zur Wiesch ◽  
Christine Petersen-Benz ◽  
...  
Keyword(s):  
Blood Donors ◽  
Statistical Significance ◽  
University Hospital ◽  
Genotype 3 ◽  
Seropositivity Rate ◽  
Future Studies ◽  
Age Related ◽  
Immune Mediated ◽  
The University ◽  
Age And Sex

Among numerous other immune-mediated diseases, glomerulonephritis has also been suspected to be an extrahepatic manifestation of HEV infection. In this prospective study, we tested 108 patients with glomerulonephritis and 108 age- and sex-matched healthy controls at the University Hospital Hamburg Eppendorf, Hamburg, Germany, for anti-HEV IgG (Wantai test) as a marker for previous HEV exposure. A total of 24 patients (22%) tested positive for anti-HEV IgG. Males tended to be more frequently anti-HEV IgG positive (29%) in comparison to females (16%). However, this does not reach statistical significance (p = 0.07). Anti-HEV IgG positive patients were older in comparison to negative patients (mean 53 vs. 45 years, p = 0.05). The kidney function seems to be slightly decreased in anti-HEV IgG positive patients in comparison to and anti-HEV IgG negative patients basing on creatinine (p = 0.04) and glomerular filtration rate (GFR) (p = 0.05). Slightly higher values of bilirubin could be found in IgG positive patients (p = 0.04). Anti-HEV-IgG seropositivity rate (22%) in glomerulonephritis patients, did not differ significantly in comparison to an age- and sex-matched control cohort of healthy blood donors (31/108 positive, 29%). A total of 2/2 patients with membranoproliferative glomerulonephritis (MPGN) tested anti-HEV IgG positive (p = 0.002 in comparison to glomerulonephritis patients with other subtypes).In conclusion, our findings indicate that previous HEV exposure in a region where GT3 is endemic is not associated with glomerulonephritis in general. However, the subgroup of MPGN patients should be investigated in future studies. Furthermore, future studies are needed to investigate whether the observed association between anti-HEV IgG positivity and reduced GFR in glomerulonephritis patients is HEV associated or is an age-related effect.

scholarly journals Beyond History: A Legacy and a Vision

2015 ◽  
Vol 49 (1) ◽  
Author(s):  
Leonor I. Cabral-Lim ◽  
Martesio C. Perez
Keyword(s):  
Past History ◽  
Health Sciences ◽  
The Philippines ◽  
University Hospital ◽  
Professor Emeritus ◽  
The Past ◽  
The Future ◽  
University History ◽  
National University ◽  
The University

Introduction This work is a tribute to all those who have shaped the Department of Neurosciences of the National University Hospital and the University of the Philippines Health Sciences Center. I am deeply honored to have collaborated with my highly esteemed mentor and colleague, Dr. Martesio Perez, Professor Emeritus of the University. History is more than a chronology of the past. There is much more beyond the names and events of the past. History has not only made us what we are today, but will also guide us to where we want to be in the future. As the historian David McCullough stated, "History is an unending dialogue between the past and the present." This written history starts at the present, goes back in time, and moves forward toward our envisioned future.

scholarly journals University Medicine in Italy: an exemplary “case report” of several unresolved criticities

2010 ◽  
Vol 4 (4) ◽  
pp. 145-155
Author(s):  
Roberto Manfredi
Keyword(s):  
Academic Medicine ◽  
Point Of View ◽  
University Hospital ◽  
Professional Activity ◽  
The Past ◽  
University Medicine ◽  
Medical Division ◽  
Starting Point ◽  
The University ◽  
Present Role

The present role, space, task, mission, function, and outcome of University Medicine in Italy are briefly examined, taking as a pure and trivial pretext the actual professional activity of single, representative physician who changed his role at the same specialistic Department of the same University Hospital, by covering an University role in the past five years, after working at the same facility as an Hospital-affiliated specialist in charge of the same Medical Division during the previous 14 years. The lights and shadows of assistential and academic medicine organisation and integration in Italy are the starting point of our preliminary observations, which may be potentially extended to the University Medicine as a whole, from an organisative, functional, and especially ergonomic point of view.

Regulation in research ethics: a scarecrow for physicians?

2021 ◽  
pp. 147775092098357
Author(s):  
T Haaser ◽  
D Berdaï ◽  
S Marty ◽  
V Berger ◽  
E Augier ◽  
...  
Keyword(s):  
Research Ethics ◽  
Research Process ◽  
University Hospital ◽  
Medical Community ◽  
Clinical Practices ◽  
The Past ◽  
Institutional Review ◽  
General Data ◽  
Research Initiatives ◽  
The University

Background Regulations on research ethics in France have evolved considerably over the past four years: the implementation of the Jardé law and of the General Data Protection Regulations have changed the landscape of research ethics for research involving or not involving human persons. In a context of creation of an Institutional Review Board at the University of Bordeaux, France, we sought to explore research ethics practices and perceptions in the medical community of our University Hospital. Methods A short questionnaire was sent to all physicians of the University Hospital of Bordeaux. The questionnaire included closed questions and main topics were: physicians’ education in research ethics, ethics practices concerning researches non implying human persons, and physicians’ perceptions about current regulations. Results 86 questionnaires were sent back (response rate: 24.2%). If a majority of physicians have validated Good Clinical Practices (GCPs) trainings (76%), there was a low rate of specific training on fundamental references in research ethics and a high proportion of responders do not consider themselves as educated in research ethics after completion of GCPs (56%). Regulations on research ethics have many implications on medical research, especially by inducing changes in protocols in order to alleviate ethical requirements (57%). Malpractices were acknowledged like false mention of positive opinion from an ethics committee (21%). If If a majority of responders considers regulations as a positive answer to research ethics, a large majority considers it as a constraint and a complexification of research process. For 58%, regulations in research ethics are perceived as a hindrance for research initiatives. Conclusion Because of their impact on research process, regulations seem to constitute a scarecrow for physicians. Lack of training, bad representations and questionable practices (or even malpractices) highlight the need to improve education and to propose concrete guidance for medical researchers.

scholarly journals A multidisciplinary approach to mental illness: do inflammation, telomere length and microbiota form a loop? A protocol for a cross-sectional study on the complex relationship between inflammation, telomere length, gut microbiota and psychiatric disorders

BMJ Open ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. e032513 ◽  
Author(s):  
Mirko Manchia ◽  
Pasquale Paribello ◽  
Carlo Arzedi ◽  
Alberto Bocchetta ◽  
Paola Caria ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Psychiatric Disorders ◽  
Telomere Length ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Telomere Shortening ◽  
Age Related ◽  
The University

IntroductionSevere psychiatric disorders are typically associated with a significant reduction in life expectancy compared with the general population. Among the different hypotheses formulated to explain this observation, accelerated ageing has been increasingly recognised as the main culprit. At the same time, telomere shortening is becoming widely accepted as a proxy molecular marker of ageing. The present study aims to fill a gap in the literature by better defining the complex interaction/s between inflammation, age-related comorbidities, telomere shortening and gut microbiota in psychiatric disorders.Methods and analysisA cross-sectional study is proposed, recruiting 40 patients for each of three different diagnostic categories (bipolar disorder, schizophrenia and major depressive disorder) treated at the Section of Psychiatry and at the Unit of Clinical Pharmacology of the University Hospital Agency of Cagliari (Italy), compared with 40 age-matched and sex-matched non-psychiatric controls. Each group includes individuals suffering, or not, from age-related comorbidities, to account for the impact of these medical conditions on the biological make-up of recruited patients. The inflammatory state, microbiota composition and telomere length (TL) are assessed.Ethics and disseminationThe study protocol was approved by the Ethics Committee of the University Hospital Agency of Cagliari (PG/2018/11693, 5 September 2018). The study is conducted in accordance with the principles of good clinical practice and the Declaration of Helsinki, and in compliance with the relevant Italian national legislation. Written, informed consent is obtained from all participants. Participation in the study is on a voluntary basis only. Patients will be part of the dissemination phase of the study results, during which a local conference will be organised and families of patients will also be involved. Moreover, findings will be published in one or more research papers and presented at national and international conferences, in posters or oral communications.

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