scholarly journals Nosocomial Staphylococcal Toxic Shock. Case Report

2016 ◽  
Vol 2 (3) ◽  
pp. 142-144
Author(s):  
Manuela Arbune ◽  
Loredana Tercu
Keyword(s):  
Nitrogen Retention ◽  
Sudden Onset ◽  
Multiple Organ ◽  
Fluid Replacement ◽  
Biliary Colic ◽  
Toxic Shock ◽  
Lethal Infection ◽  
History Of ◽  
Staphylococcal Toxic Shock Syndrome ◽  
Inflammatory Syndrome

Abstract Staphylococcal toxic shock syndrome (STSS) is a rare, potentially lethal infection, with a clinical picture of multiple organ dysfunction and shock. The etiology is Staphylococcus aureus exotoxin, while enterotoxins act as superantigens. Most cases are identified in women using a vaginal tampon. A 51-year-old female, with a past medical history of biliary dyskinesia, presented in the emergency room complaining of sudden onset of abdominal pain, vomiting, headache, myalgia, and chills. The initial diagnosis was biliary colic and was treated parenterally with Amoxi-clavulanate and fluid replacement. Initially, progress was unsatisfactory. Four days after admission she developed a systemic inflammatory syndrome, diffuse rash, jaundice, oliguria, confusion, persistent hypotension and biological evidence of thrombocytopenia, nitrogen retention, and cholestasis. She was admitted to the intensive care unit. A gluteal phlegmon induced after intramuscular injections was identified and surgically treated. Blood bacteriological cultures were negative, though MRSA was isolated in phlegmon pus. A diagnosis of STSS was based on CDC criteria. The risks of similar infections could be prevented by limiting intramuscular treatments and monitoring invasive procedures.

scholarly journals Post-COVID-19 Kawasaki-Like Syndrome

2021 ◽  
pp. 014556132110060
Author(s):  
Jérôme R. Lechien ◽  
Rémi Hervochon ◽  
Stéphane Hans
Keyword(s):  
Abdominal Pain ◽  
Multiple Organ Failure ◽  
Organ Failure ◽  
Hepatitis A ◽  
Clinical Presentation ◽  
Multiple Organ ◽  
Mild Form ◽  
Severe Dysphagia ◽  
History Of ◽  
Inflammatory Syndrome

A 42-year-old man was referred for a week history of severe dysphagia, odynophagia, fever (39 °C), fatigue, abdominal pain, pharyngeal swelling, and multiple neck lymphadenopathies. The medical history reported a mild form of COVID-19 one month ago. The biology reported an unspecified inflammatory syndrome. The patient developed peritonitis, myocarditis, and hepatitis. A myocardium biopsy was performed. A diagnosis of Kawasaki-like disease (KLD) was performed. The occurrence of KLD in adults is rare but has to be known by otolaryngologists regarding the otolaryngological clinical presentation that may precede the multiple organ failure.

scholarly journals Pustules on the back possibly triggering toxic-shock syndrome

2019 ◽  
Vol 12 (6) ◽  
pp. e229610
Author(s):  
Hideharu Hagiya ◽  
Futoshi Nakagami ◽  
Yuki Minami ◽  
Hiroaki Terada
Keyword(s):  
Toxic Shock Syndrome ◽  
Gastrointestinal Symptoms ◽  
Sudden Onset ◽  
Multiple Organ ◽  
High Fever ◽  
Toxic Shock ◽  
Old Japanese ◽  
The Face ◽  
Organ Failures ◽  
Irregular Case

We herein describe an irregular case of toxic-shock syndrome (TSS). A previously healthy 28-year-old Japanese man developed a sudden-onset high fever. The patient was suffering from conjunctival hyperaemia, gastrointestinal symptoms such as vomiting and diarrhoea, and systemically diffused macular erythroderma. Further physical examination detected pustules on his back, which self-destructed over time. Laboratory revealed multiple organ failures. Subsequently, scalded skin on the face and desquamation in the limb extremities emerged by day 10, leading to the diagnosis of TSS, despite his stable circulatory dynamics through the course. Learning points for clinicians include that they should recall TSS as a possible disease concurrently causing high fever, systemic rash and multiple organ dysfunctions, even without being in a state of shock. The characteristic desquamations emerged in the limb extremities after hospitalisation were of help in diagnosing TSS.

scholarly journals COVID-19 and multi-system inflammatory syndrome in children: keep a high index of suspicion in all inflammatory disorders

2021 ◽  
Vol 8 (4) ◽  
pp. 747
Author(s):  
Fatima Afreen Ahmad ◽  
Munesh Tomar ◽  
Umang Arora
Keyword(s):  
Health Care Professionals ◽  
Care Center ◽  
Tertiary Care ◽  
Uttar Pradesh ◽  
Multiple Organ ◽  
Organ System ◽  
Toxic Shock ◽  
Inflammatory Conditions ◽  
High Index Of Suspicion ◽  
Inflammatory Syndrome

COVID-19 pandemic put many challenges for the health care professionals and one of that is the multi-system inflammatory syndrome in children (MIS-C). This syndrome shares its features with other inflammatory conditions including Kawasaki disease and toxic shock syndrome. We are reporting 4 cases from a tertiary care center in COVID-19 hotspot area in the state of Uttar Pradesh who presented with multiple organ system involvement. 

scholarly journals Case Series of Multisystem Inflammatory Syndrome (MIS-C) in Children during the SARS-CoV-2 Pandemic in Latvia

2021 ◽  
Vol 11 (2) ◽  
pp. 363-373
Author(s):  
Iveta Racko ◽  
Liene Smane ◽  
Lizete Klavina ◽  
Zanda Pucuka ◽  
Ieva Roge ◽  
...  
Keyword(s):  
Case Series ◽  
Multiple Organ ◽  
Special Focus ◽  
Antibody Testing ◽  
Median Hospital Stay ◽  
Organ Systems ◽  
Treatment Data ◽  
History Of ◽  
Inflammatory Syndrome

The total number of COVID-19 positive cases in Latvia has escalated rapidly since October 2020, peaking in late December 2020 and early January 2021. Children generally develop COVID-19 more mildly than adults; however, it can be complicated by multisystem inflammatory syndrome in children (MIS-C). This case study aims were to assess demographic characteristics and the underlying medical conditions, and clinical, investigative and treatment data among 13 MIS-C patients using electronic medical records. All 13 had acute illness or contact with someone who was COVID-19 positive two to six weeks before MIS-C onset. Only five of the 13 were symptomatic during the acute COVID-19 phase. The median age was 8.8 years; 11/13 patients were male, 10/13 had been previously healthy, and all 13 patients tested positive for SARS-CoV-2 by RT-PCR or antibody testing. The most commonly involved organ systems were the gastrointestinal (13/13), hematologic (13/13), cardiovascular (13/13), skin and mucosa (13/13), and respiratory (12/13) ones. The median hospital stay was 13 (interquartile range, 11 to 18) days; 7/13 patients received intensive care, 6/13 oxygen support, and 5/13 received inotropic support. No deaths occurred. During the current pandemic, every child with a fever should have a clearly defined epidemiological history of COVID-19, a careful clinical assessment of possible multiple organ-system involvement, with a special focus on children with severe abdominal pain and/or skin and mucocutaneous lesions.

scholarly journals The Management of Staphylococcal Toxic Shock Syndrome. A Case Report

2016 ◽  
Vol 2 (2) ◽  
pp. 85-88 ◽  
Author(s):  
Victoria Bîrluţiu ◽  
Ofelia Criştiu ◽  
Marius Baicu ◽  
Rareş Mircea Bîrluţiu
Keyword(s):  
Toxic Shock Syndrome ◽  
Treatment Plan ◽  
Diuretic Therapy ◽  
Local Treatment ◽  
Multiple Organ ◽  
Toxic Shock ◽  
Central Nervous System Damage ◽  
Organ Failures ◽  
Liver And Kidney ◽  
Staphylococcal Toxic Shock Syndrome

Abstract Staphylococcal toxic shock syndrome (TSS) is most frequently produced by TSS toxin-1 (TSST-1) and Staphylococcal enterotoxin B (SEB), and only rarely by enterotoxins A, C, D, E, and H. Various clinical pictures can occur depending on severity, patient age and immune status of the host. Severe forms, complicated by sepsis, are associated with a death rate of 50-60%. The case of a Caucasian female infant, aged seven weeks, hospitalized with a diffuse skin rash, characterized as allergodermia, who initially developed TSS with axillary intertrigo, is reported. TSS was confirmed according to 2011 CDC criteria, and blood cultures positive for Methicillin-sensitive Staphylococcus aureus (MSSA). Severe development occurred initial, including acidosis, consumption coagulopathy, multiple organ failures (MOF), including impaired liver and kidney function. Central nervous system damage was manifest by seizures. Clinical management included medical supervision by a multidisciplinary team of infectious diseases specialist and intensive care specialist, as well as the initiation of a complex treatment plan to correct hydro electrolytic imbalances and acidosis. This treatment included antibiotic and antifungal therapy, diuretic therapy, immunoglobulins, and local treatment similar to a patient with burns to prevent superinfection of skin and mucous membranes lesions. There was a favourable response to the treatment with resolution of the illness.

scholarly journals A Novel and Severe Clinical Picture Related to COVID-19: Multi-Inflammatory Syndrome in Children

2021 ◽  
Author(s):  
Fatih Haşlak ◽  
Mehmet Yıldız ◽  
Sezgin Şahin ◽  
Amra Adrovic Yıldız ◽  
Kenan Barut ◽  
...  
Keyword(s):  
Macrophage Activation ◽  
Clinical Findings ◽  
Disease Course ◽  
Toxic Shock ◽  
Active Infection ◽  
Severe Clinical Picture ◽  
Life Threatening ◽  
History Of ◽  
Distinct Features ◽  
Inflammatory Syndrome

Preliminary data have suggested that children have milder COVID-19 disease course compared to adults. However, pediatric cases with severe clinical findings caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) are being reported since April 2020. These children have been presented with significant hyperinflammatory states resembling Kawasaki disease, toxic shock syndrome, and macrophage activation syndrome. However, they had several distinct features, as well. Therefore, this novel condition was considered a unique disease and named Multi-inflammatory syndrome in children (MIS-C). Thus, new concerns have been raised regarding the vulnerability of the children. However, it has been realized that this condition is extremely rare. Nonetheless, considering that it is a life-threatening disease and may cause devastating consequences, clinicians should be aware of MIS-C while evaluating children with persistent fever and history of COVID-19 contact or active infection.

scholarly journals Staphylococcal toxic shock syndrome in a child. Case report

2021 ◽  
Vol 4 (3) ◽  
pp. 302-307
Author(s):  
G.S. Karpovich ◽  
◽  
I.V. Kuimova ◽  
E.I. Krasnova ◽  
D.S. Maramygin ◽  
...  
Keyword(s):  
Case Report ◽  
Toxic Shock Syndrome ◽  
Group A Streptococcus ◽  
Wound Care ◽  
Pathological Condition ◽  
Multiple Organ ◽  
Toxic Shock ◽  
Causative Agents ◽  
Focus Of Infection ◽  
Staphylococcal Toxic Shock Syndrome

Toxic shock syndrome (TSS) is a complex of symptoms that includes fever, exanthem, multiple organ dysfunction syndrome, and hypotension. The most common causative agents are S. aureus and group A Streptococcus. TSS is characterized by severe course and high mortality in the lack of specific complex treatment. This article addresses a case report of staphylococcal TSS in a 5-year-old girl. The primary focus of infection (infected right leg wound) and breakthrough factors (the lack of adequate wound care) resulted in the dissemination of causative agent and TSS development. Despite disease severity, early complex etiological (antibiotics) and pathogenically-oriented (infusions, corticosteroids) treatment improved the patient’s condition and promoted recovery. This case report illustrating the classic presentations of staphylococcal TSS in children is helpful for pediatricians in terms of awareness of this pathological condition. KEYWORDS: infectious diseases, staphylococcus aureus, toxic shock syndrome, cytokine storm, multiple organ failure syndrome, pediatrics. FOR CITATION: Karpovich G.S., Kuimova I.V., Krasnova E.I. et al. Staphylococcal toxic shock syndrome in a child. Case report. Russian Journal of Woman and Child Health. 2021;4(3):302–307 (in Russ.). DOI: 10.32364/2618-8430-2021-4-3-302-307.

scholarly journals MULTISYSTEM INFLAMMATORY SYNDROME IN A CHILD ASSOCIATED WITH CORONAVIRUS DISEASE 19 IN THE BRAZILIAN AMAZON: FATAL OUTCOME IN AN INFANT

2020 ◽  
Vol 38 ◽  
Author(s):  
Emmerson Carlos Franco de Farias ◽  
Maria Cleonice Aguiar Justino ◽  
Mary Lucy Ferraz Maia Fiuza de Mello
Keyword(s):  
Troponin I ◽  
Fatal Outcome ◽  
Multiple Organ ◽  
Multiple Organ Dysfunction ◽  
Extreme Prematurity ◽  
Low Weight ◽  
History Of ◽  
Special Concern ◽  
Inflammatory Syndrome ◽  
D Dimer

ABSTRACT Objective: Recently, there have been reports of children with severe inflammatory syndrome and multiorgan dysfunction associated with elevated inflammatory markers. These cases are reported as presenting the Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19. In this study, we describe with parental permission a case of MIS-C in an infant with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Case description: A seven-month-old infant, with SARS-CoV-2 infection and a history of extreme preterm birth and very low weight at birth, with an initial course of mild respiratory symptoms and abrupt progression to vasoplegic shock, myocarditis and hyperinflammation syndrome, shown by high levels of troponin I, ferritin, CRP, D-dimer and hypoalbuminemia. Despite the intensive care provided, the child developed multiple organ dysfunction and died. Comments: Patients with a history of extreme prematurity may present with MIS-C in the presence of COVID-19 and are a group of special concern.

THERAPEUTIC MANAGEMENT OF ASCITES IN SPITZ DOG IN BANGLADESH WITH A BRIEF REVIEW ON CANINE ASCITES

2019 ◽  
Vol 1 (1) ◽  
Author(s):  
M. A. Samad
Keyword(s):  
Ascitic Fluid ◽  
Clinical Examination ◽  
Clinical Case ◽  
Abdominal Distension ◽  
Multiple Organ ◽  
Therapeutic Management ◽  
Vitamin Supplement ◽  
Case Record ◽  
Successful Recovery ◽  
History Of

Background: Ascites is one of the most important clinical syndromes, caused by multiple organ disorders, characterized by abdominal distension with accumulation of fluid of various colors and consistencies depending on the etiology that are encountered commonly in canine practice worldwide. Although it has been reported from different countries including India but it has not yet been documented from Bangladesh. Objectives: To evaluate the successful therapeutic management of a clinical case of ascites in dog supported with its brief review for its appropriate application Materials and Methods: A female Spitz dog two and half years old brought for treatment with the history of abdominal distension on 1st November 2009. Clinical examination, abdominocentesis and laboratory examination of ascitic fluid were used for the diagnosis of ascites in dog. Results: Clinical examination revealed dyspnea, discomfort, lethargy, weakness, pale mucous membrane, normal rectal temperature 103.2 0F and distended abdomen with fluid thrill on palpation. Examination of ascitic fluid revealed clear white fluid (pure transudate) which is mainly hepatic origin resulting portal hypertension and hypoproteinaemia. Treatment with restricted sodium diet, antibiotic (amoxicillin), diuretic (furosemide; Lasix, Sanofi Aventis) and vitamin B-complex and C- vitamin supplement with regular monitoring assisted in successful recovery. The recovered dog survived for next five years up to 2014 and then died due to other reasons. Conclusions: This clinical case record on canine ascites with successful treatment along with review especially on the methods of diagnosis and cause-wise treatment would certainly help the clinician for proper management of the clinical cases of canine ascites. Keywords: Ascites, Spitz dog, Diagnosis, SAAG, Therapeutic management, Brief review

Sigmoid Volvulus in 16-year-old Boy with an Associated Anomalous Congenital Band

2013 ◽  
Vol 79 (11) ◽  
pp. 1140-1141 ◽  
Author(s):  
Ann A. Albert ◽  
Tracy L. Nolan ◽  
Bryan C. Weidner
Keyword(s):  
Abdominal Pain ◽  
African American Male ◽  
Pediatric Patients ◽  
Primary Anastomosis ◽  
Exploratory Laparotomy ◽  
Sigmoid Volvulus ◽  
Sudden Onset ◽  
Contrast Enema ◽  
Pediatric Age Group ◽  
History Of

Sigmoid volvulus, a condition generally seen in debilitated elderly patients, is extremely rare in the pediatric age group. Frequent predisposing conditions that accompany pediatric sigmoid volvulus include intestinal malrotation, omphalomesenteric abnormalities, Hirschsprung's disease, imperforate anus and chronic constipation. A 16-year-old previously healthy African American male presented with a 12 hour history of sudden onset abdominal pain and intractable vomiting. CTwas consistent with sigmoid volvulus. A contrast enema did not reduce the volvulus, but it was colonoscopically reduced. Patient condition initially improved after colonoscopy, but he again became distended with abdominal pain, so he was taken to the operating room. On exploratory laparotomy, a band was discovered where the mesenteries of the sigmoid and small bowel adhered and created a narrow fixation point around which the sigmoid twisted. A sigmoidectomy with primary anastomosis was performed. The diagnosis of sigmoid volvulus may be more difficult in children, with barium enema being the most consistently helpful. Seventy percent of cases do not involve an associated congenital problem, suggesting that some pediatric patients may have congenital redundancy of the sigmoid colon and elongation of its mesentery. The congenital band found in our patient was another potential anatomic factor that led to sigmoid volvulus. Pediatric surgeons, accustomed to unusual problems in children, may thus encounter a condition generally found in the debilitated elderly patient.

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