Non-HDL-cholesterol and C-reactive protein in children and adolescents with type 1 diabetes

2017 ◽  
Vol 30 (3) ◽  
Author(s):  
María Mercedes Prado ◽  
Teresita Carrizo ◽  
Adela Victoria Abregú ◽  
Tomás Meroño
Keyword(s):  
Risk Factors ◽  
Type 1 Diabetes ◽  
Cardiovascular Risk ◽  
Subgroup Analysis ◽  
Hdl Cholesterol ◽  
High Sensitivity ◽  
C Reactive Protein ◽  
Endocrine Diseases ◽  
Reactive Protein

AbstractBackground:To what extent high sensitivity C-reactive protein (hsCRP) is associated with known cardiovascular risk factors in children with type 1 diabetes (T1D) has not been fully explored.Methods:Forty-two T1D children (age: 12+/−1 years) without hypertension, retinopathy, hypothyroidism, albuminuria or other endocrine diseases and 20 controls were studied. Out of the 42 T1D patients studied 57% were prepubertal or early pubertal (Tanner I/II), 38% were pubertal (Tanner III/IV) and 5% post-pubertal (Tanner V).Results:Children with T1D showed higher hsCRP than controls [0.51 (0.31–1.71 vs. 0.20 (0.20–0.90) mg/L, p<0.05]. However, hsCRP levels were not different in subgroup analysis [hemoglobin AConclusions:Non-HDL-cholesterol might be more useful than hsCRP to evaluate future cardiovascular risk in children with T1D.

Assessment of SerumYkl-40 and High Sensitivity C-Reactive Protein as Biomarkers of Renal Affection of Children with Type 1 Diabetes

2021 ◽  
Vol 84 (1) ◽  
pp. 2337-2343
Author(s):  
Sabry Abdel Rahman Tolba ◽  
Hadeel Mohammad Abd-Elrahman ◽  
Randa Hussiny Mohamed ◽  
Khaled Abdulhafid Moftah Hendi
Keyword(s):  
Type 1 Diabetes ◽  
High Sensitivity ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals Children with type 1 diabetes have elevated high sensitivity C-reactive protein compared to a control group

2020 ◽  
Author(s):  
Pilar Pérez-Segura ◽  
Olaya de Dios ◽  
Leticia Herrero ◽  
Claudia Vales-Villamarín ◽  
Isabel González-Aragón ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Waist Circumference ◽  
High Sensitivity ◽  
Control Group ◽  
Z Score ◽  
C Reactive Protein ◽  
Anthropometric Parameters ◽  
Reactive Protein

Abstract Objectives To compare high sensitivity C-reactive protein (hsCRP) levels in children with type 1 diabetes, healthy controls, and children with obesity. Additionally, we aimed to analyze the association between hsCRP levels and glycemic control measured by glycohemoglobin A (HbA1c) and anthropometric and biochemical variables. Methods We conducted a non-randomized descriptive study of children with type 1 diabetes matched for sex and age with a control group and group with obesity. We recorded anthropometric parameters and studied variables related to diabetes, blood pressure, lipid profile, and HbA1c. HsCRP was measured by ELISA.Results We included 49 children with type 1 diabetes, 46 controls, and 40 children with obesity. hsCRP levels were significantly higher in the group with type 1 diabetes compared to controls and nearly significantly lower than in the group comprising children with obesity. We found no correlation between hsCRP and HbA1C and characteristics of type 1 diabetes with the exception of albuminin creatinine ratio (ACR). Statistically significant association was found between hsCRP and BMI and waist circumference Z-score. Conclusions Children with type 1 diabetes have a higher hsCRP than healthy subjects; this difference is not associated with HbA1c, but is related to waist circumference, BMI, and ACR. Obesity prevention should be a priority when performing follow-up in children with type 1 diabetes.

High Sensitivity C-reactive Protein And Cardiovascular Risk Factors In Professional Soccer Players

2014 ◽  
Vol 46 ◽  
pp. 745-746
Author(s):  
Francisco J. Diaz ◽  
Magdalena Najera ◽  
Antonio Tovar ◽  
Flora Moreno ◽  
Agustin Moreno ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
High Sensitivity ◽  
Soccer Players ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Professional Soccer

scholarly journals High-sensitivity C-reactive protein is a good marker of cardiovascular risk in obese children and adolescents.

2008 ◽  
Vol 159 (1) ◽  
pp. R1-R4 ◽  
Author(s):  
Leandro Soriano-Guillén ◽  
Bárbara Hernández-García ◽  
Jimena Pita ◽  
Nieves Domínguez-Garrido ◽  
Genoveva Del Río-Camacho ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Children And Adolescents ◽  
Hdl Cholesterol ◽  
High Sensitivity ◽  
Oral Glucose ◽  
Obese Children ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Hs Crp

ObjectiveWe intend to assess the utility of the high-sensitivity C-reactive protein (hs-CRP) as a marker of cardiovascular risk in obese children and adolescents.MethodsThe study included children and adolescents between 6 and 18 years of age with a body mass index (BMI) higher than 2 SDS. All the patients had their blood pressure taken and hs-CRP, hepatic function, lipid profile and uric acid were determined after 12 h of fasting. Likewise, an oral glucose tolerance test was performed, determining basal glucose and insulin levels, and after stimulus. We considered the presence of metabolic syndrome when the obese children and teenagers showed at least two of the following conditions: decreased high density lipoprotein (HDL)-cholesterol, hypertriglyceridemia, hypertension or alteration in glucose metabolism.ResultsOut of the 115 obese children studied, 24% showed signs of metabolic syndrome. Those with metabolic syndrome presented higher levels of hs-CRP (mean: 3.8 mg/l; 95% CI: 2.8–4.8) in comparison with the obese patients who did not show signs of metabolic syndrome (mean: 2 mg/l; 95% CI: 1.5–2.5). After a multivariate analysis, the variables that appear to influence the changes in hs-CRP were BMI, triglycerides and HDL-cholesterol levels.ConclusionThe hs-CRP is a useful tool for early diagnosis of cardiovascular risk in obese children and teenagers.

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