scholarly journals Molecular imprinted photonic crystal for sensing of biomolecules

2016 ◽  
Vol 4 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Wei Chen ◽  
Zihui Meng ◽  
Min Xue ◽  
Kenneth J Shea
Keyword(s):  
Photonic Crystal ◽  
Molecular Imprinting ◽  
Binding Capacity ◽  
Optical Signal ◽  
Molecularly Imprinted ◽  
Effective Strategies ◽  
Tremendous Progress ◽  
Binding Event ◽  
Potential Applications ◽  
Molecule Recognition

AbstractMolecularly imprinted polymers (MIPs) are highly cross-linked polymers with high binding capacity and selectivity to the target molecules. MIPs become increasingly important because of the potential applications in drug delivery, purification and separation. In spite of the tremendous progress that has been made in the molecular imprinting field, many challenges remain to be addressed, especially in transforming the binding event into a detectable optical signal. The combination of photonic crystal and molecular imprinting technique is becoming a popular research idea. Compared to the conventional MIPs, the molecularly imprinted photonic crystal sensors (MIPCB) have the advantage of directly convert the molecule recognition process into optical signal. This review comprehensively summarizes various MIPCB, including the principle of molecular imprinted photonic crystal sensors, recent development, some challenges and effective strategies for MIPCB.

Fluorescence signaling molecularly imprinted polymers for antibiotics prepared via site-directed post-imprinting introduction of plural fluorescent reporters within the recognition cavity

2016 ◽  
Vol 4 (44) ◽  
pp. 7138-7145 ◽  
Author(s):  
Hirobumi Sunayama ◽  
Takeo Ohta ◽  
Atsushi Kuwahara ◽  
Toshifumi Takeuchi
Keyword(s):  
Molecular Imprinting ◽  
Molecularly Imprinted Polymers ◽  
Fluorescent Dyes ◽  
Specific Binding ◽  
Fluorescence Signal ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Fluorescent Reporters ◽  
Binding Event ◽  
Fluorescence Signaling

An antibiotic-imprinted cavity with two different fluorescent dyes was prepared by molecular imprinting and subsequent post-imprinting modifications (PIMs), for the readout of a specific binding event as a fluorescence signal.

A molecularly imprinted colloidal array as a colorimetric sensor for label-free detection of p-nitrophenol

2014 ◽  
Vol 6 (3) ◽  
pp. 831-837 ◽  
Author(s):  
Fei Xue ◽  
Zihui Meng ◽  
Yifei Wang ◽  
Shuyue Huang ◽  
Qiuhong Wang ◽  
...  
Keyword(s):  
Photonic Crystal ◽  
Molecular Imprinting ◽  
Colorimetric Sensor ◽  
Label Free ◽  
Molecularly Imprinted ◽  
Label Free Detection ◽  
Molecular Imprinting Technique ◽  
Crystalline Colloidal Array

We report on the synthesis of a label-free p-nitrophenol (PNP) responsive crystalline colloidal array (CCA) based on the combination of a photonic crystal and the molecular imprinting technique.

An all optical photonic crystal half adder suitable for optical processing applications

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Hamed Azhdari ◽  
Sahel Javahernia
Keyword(s):  
Photonic Crystal ◽  
Optical Waveguides ◽  
High Speed ◽  
Building Blocks ◽  
Optical Signal ◽  
Ring Resonators ◽  
Optical Processing ◽  
Nonlinear Photonic Crystal ◽  
Half Adder ◽  
All Optical

Abstract Increasing the speed of operation in all optical signal processing is very important. For reaching this goal one needs high speed optical devices. Optical half adders are one of the important building blocks required in optical processing. In this paper an optical half adder was proposed by combining nonlinear photonic crystal ring resonators with optical waveguides. Finite difference time domain method wase used for simulating the final structure. The simulation results confirmed that the rise time for the proposed structure is about 1 ps.

Molecularly imprinted nanozymes with faster catalytic activity and better specificity

Nanoscale ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 4854-4863 ◽  
Author(s):  
Zijie Zhang ◽  
Yuqing Li ◽  
Xiaohan Zhang ◽  
Juewen Liu
Keyword(s):  
Activation Energy ◽  
Catalytic Activity ◽  
Molecular Imprinting ◽  
Selective Adsorption ◽  
Molecularly Imprinted ◽  
Product Release

Molecular imprinting accelerates nanozyme catalysis and improves specificity attributable to selective adsorption of imprinted substrate, decreasing activation energy and facilitating product release.

Synthesis and Properties of Molecularly Imprinted Composite Membranes of Roxithromycin

2009 ◽  
Vol 87-88 ◽  
pp. 80-85
Author(s):  
Jin Yang Yu ◽  
Xiao Ling Hu ◽  
Cui Cui Jiao ◽  
Ya Mei Zhao ◽  
Wei Wei Yang
Keyword(s):  
Cross Sections ◽  
Binding Capacity ◽  
Composite Membranes ◽  
Ethanol Solution ◽  
Differential Scanning Calorimetric ◽  
Separation Mechanism ◽  
Molecularly Imprinted ◽  
Filtration Membranes ◽  
Ultra Filtration ◽  
Imprinted Membrane

Molecularly imprinted composite membranes for selective binding and permeation of roxithromycin were prepared by means of thermal initiated co-polymerization method using polysulfone ultra-filtration membranes as porous supports. Scanning electron microscope was utilized to visualize surface and cross-sections of the membranes to gain more better understanding in the analysis of imprinted layers deposited on PSF support membranes and differential scanning calorimetric was used for determining the thermal stability of the membranes. Static equilibrium binding and recognition properties of the imprinted and non-imprinted membranes to roxithromycin and its analogues in ethanol solution system were tested. The results showed that saturated binding capacity of imprinted membrane to roxithromycin was about 2.24μmol/g, higher than those of its analogues, and the selectivity factors of αRM/EM, αRM/AM and αRM/EE were 1.75, 2.46 and 2.67, respectively. The transport performances of the membranes were evaluated through kinetic filtration experiments. The separation mechanism of the roxithromycin imprinted membrane could be defined as facilitated permeation mechanism.

scholarly journals Colorimetric Sensing of Amoxicillin Facilitated by Molecularly Imprinted Polymers

Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2221
Author(s):  
Joseph W Lowdon ◽  
Hanne Diliën ◽  
Bart van Grinsven ◽  
Kasper Eersels ◽  
Thomas J. Cleij
Keyword(s):  
Binding Capacity ◽  
Colorimetric Detection ◽  
Bulk Polymerization ◽  
Colorimetric Sensing ◽  
Initial Development ◽  
Molecularly Imprinted ◽  
Synthetic Receptor ◽  
Displacement Assay ◽  
Size And Morphology ◽  
Task Sets

The scope of the presented research orientates itself towards the development of a Molecularly Imprinted Polymer (MIP)-based dye displacement assay for the colorimetric detection of the antibiotic amoxicillin in aqueous medium. With this in mind, the initial development of an MIP capable of such a task sets focus on monolithic bulk polymerization to assess monomer/crosslinker combinations that have potential towards the binding of amoxicillin. The best performing composition (based on specificity and binding capacity) is utilized in the synthesis of MIP particles by emulsion polymerization, yielding particles that prove to be more homogenous in size and morphology compared to that of the crushed monolithic MIP, which is an essential trait when it comes to the accuracy of the resulting assay. The specificity and selectivity of the emulsion MIP proceeds to be highlighted, demonstrating a higher affinity towards amoxicillin compared to other compounds of the aminopenicillin class (ampicillin and cloxacillin). Conversion of the polymeric receptor is then undertaken, identifying a suitable dye for the displacement assay by means of binding experiments with malachite green, crystal violet, and mordant orange. Once identified, the optimal dye is then loaded onto the synthetic receptor, and the displaceability of the dye deduced by means of a dose response experiment. Alongside the sensitivity, the selectivity of the assay is scrutinized against cloxacillin and ampicillin. Yielding a dye displacement assay that can be used (semi-)quantitatively in a rapid manner.

Photonic Crystal-Embedded Molecularly Imprinted Contact Lenses for Controlled Drug Release

2021 ◽  
Author(s):  
Zhaoran Chu ◽  
Chao Xue ◽  
Kan Shao ◽  
Lanlan Xiang ◽  
Xueling Zhao ◽  
...  
Keyword(s):  
Photonic Crystal ◽  
Drug Release ◽  
Contact Lenses ◽  
Controlled Drug Release ◽  
Molecularly Imprinted

scholarly journals Infiltrated Photonic Crystal Fibers for Sensing Applications

Sensors ◽  
2018 ◽  
Vol 18 (12) ◽  
pp. 4263 ◽  
Author(s):  
José Algorri ◽  
Dimitrios Zografopoulos ◽  
Alberto Tapetado ◽  
David Poudereux ◽  
José Sánchez-Pena
Keyword(s):  
Photonic Crystal ◽  
Optical Fibers ◽  
Photonic Crystal Fibers ◽  
Scale Up ◽  
Dispersion Parameters ◽  
Power Pulse ◽  
Sensing Applications ◽  
Potential Applications ◽  
Crystal Fibers ◽  
Bose Einstein

Photonic crystal fibers (PCFs) are a special class of optical fibers with a periodic arrangement of microstructured holes located in the fiber’s cladding. Light confinement is achieved by means of either index-guiding, or the photonic bandgap effect in a low-index core. Ever since PCFs were first demonstrated in 1995, their special characteristics, such as potentially high birefringence, very small or high nonlinearity, low propagation losses, and controllable dispersion parameters, have rendered them unique for many applications, such as sensors, high-power pulse transmission, and biomedical studies. When the holes of PCFs are filled with solids, liquids or gases, unprecedented opportunities for applications emerge. These include, but are not limited in, supercontinuum generation, propulsion of atoms through a hollow fiber core, fiber-loaded Bose–Einstein condensates, as well as enhanced sensing and measurement devices. For this reason, infiltrated PCF have been the focus of intensive research in recent years. In this review, the fundamentals and fabrication of PCF infiltrated with different materials are discussed. In addition, potential applications of infiltrated PCF sensors are reviewed, identifying the challenges and limitations to scale up and commercialize this novel technology.

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