Cytotoxic Xanthones from Garcinia penangiana Pierre
2007 ◽
Vol 62
(11-12)
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pp. 786-792
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Two new xanthones, characterized as 4-(1,1-dimethylprop-2-enyl)-1,3,5,8-tetrahydroxyxanthone (1) and penangianaxanthone (2), with three known xanthones, cudratricusxanthone H (3), macluraxanthone C (4) and gerontoxanthone C (5), as well as friedelin and stigmasterol were isolated from the leaves of Garcinia penangiana. Their structures were elucidated by analysis of spectroscopic data and comparison of the NMR data with the literature ones. Significant cytotoxicity against DU-145, MCF-7 and NCI-H460 cancer cell lines was demonstrated by compounds 1D5, with IC50 values ranging from 3.5 to 72.8 μm.
2009 ◽
Vol 4
(8)
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pp. 1934578X0900400
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2018 ◽
Vol 8
(3)
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pp. 159
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Keyword(s):
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2020 ◽
Vol 19
(16)
◽
pp. 2010-2018
Keyword(s):
Keyword(s):
2011 ◽
Vol 2011
◽
pp. 1-9
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Keyword(s):