scholarly journals FAKTOR-FAKTOR KETERLAMBATAN PENDERITA KANKER PAYUDARA DALAM MELAKUKAN PEMERIKSAAN AWAL KE PELAYANAN KESEHATAN

2016 ◽  
Vol 11 (2) ◽  
pp. 276
Author(s):  
Gusti Ayu Resa Dyanti ◽  
Ni Luh Putu Suariyani
Keyword(s):  
Breast Cancer ◽  
Early Detection ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Breast Screening ◽  
Case Control ◽  
Education Level ◽  
Knowledge Level ◽  
Breast Cancer Patients ◽  
Cancer Breast

<p><strong>Abstrak</strong><br /><br />Keterlambatan penderita kanker payudara melakukan pemeriksaan awal ke pelayanan kesehatan di Indonesia mencapai lebih dari 80%. Hal ini mengakibatkan kejadian kanker payudara banyak yang ditemukan pada stadium lanjut. Penelitian ini bertujuan untuk mengetahui faktor yang berhubungan dengan keterlambatan penderita kanker payudara dalam melakukan pemeriksaan awal ke pelayanan kesehatan. Desain penelitian menggunakan studi observasional analitik dengan desain case control yang dilaksanakan pada bulan April-Mei 2015. Teknik pengambilan sampel yang digunakan concecutive sampling dan convenient sampling dengan jumlah sampel 108 orang. Hasil penelitian menunjukkan terdapat enam faktor yang memiliki hubungan bermakna dengan keterlambatan penderita kanker payudara dalam melakukan pemeriksaan awal ke pelayanan kesehatan yaitu tingkat pendidikan (tingkat pendidikan rendah p=0,001;OR 5,67 dan tingkat pendidikan sedang p=0,008;OR 3,65), tingkat pengetahuan (tingkat pengetahuan kurang p&lt;0,001;OR 15,7 dan tingkat pengetahuan cukup p=0,011;OR 9,5), keterjangkauan biaya (p=0,003;OR 5,95), keterpaparan informasi/media massa (p=0,011;OR 2,75), dukungan suami/keluarga (p&lt;0,001;OR 4,35), dan perilaku deteksi dini (tidak pernah SADARI (pemeriksaan payudara sendiri) p&lt;0,001;OR 11,08 dan tidak rutin SADARI p=0,032;OR 5.18)).</p><p>Kata Kunci : Kanker payudara; Keterlambatan Pemeriksaan Payudara; Rumah Sakit Sanglah</p><p> </p><p><em><strong>Abstract</strong></em></p><p>Almost 80% of breast cancer patients In Indonesia have delayed in breast cancer screening. The purpose of this study was to determine some factors associated with breast screening retardation of breast cancer patient. This was an analytical observational study with case control design conducted in April-May 2015. Samples were collected by consecutive sampling and convenient sampling with the number of sample  were 108. The result showed that there were six factors had a significant association with breast screening delay of breast cancer patient. Those were education level (low education level p=0,001;OR 5,67 dan moderate education level p=0,008;OR 3,65), knowledge level (low knowledge level p&lt;0,001;OR 15,7 dan moderate knowledge level p=0,011;OR 9,5), cost affordability (p=0,003;OR 5,95), information/massa media exposure (p=0,011;OR 2,75), partner/family support (p&lt;0,001;OR 4,35), and early detection behavior (have not had early detection p&lt;0,001;OR 11,08 dan infrequently early detection p=0,032;OR 5.18).<br /><br />Keyword : Breast cancer; Breast screening retardation; Sanglah Hospital.</p>

scholarly journals Serum N-glycan profiles differ for various breast cancer subtypes

2021 ◽  
Author(s):  
Gerda C. M. Vreeker ◽  
Kiki M. H. Vangangelt ◽  
Marco R. Bladergroen ◽  
Simone Nicolardi ◽  
Wilma E. Mesker ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Detection ◽  
Cancer Patients ◽  
High Resolution Mass Spectrometry ◽  
Case Control ◽  
Total Serum ◽  
Screening Methods ◽  
Breast Cancer Patients ◽  
Cancer Subtypes ◽  
Control Comparison

AbstractBreast cancer is the most prevalent cancer in women. Early detection of this disease improves survival and therefore population screenings, based on mammography, are performed. However, the sensitivity of this screening modality is not optimal and new screening methods, such as blood tests, are being explored. Most of the analyses that aim for early detection focus on proteins in the bloodstream. In this study, the biomarker potential of total serum N-glycosylation analysis was explored with regard to detection of breast cancer. In an age-matched case-control setup serum protein N-glycan profiles from 145 breast cancer patients were compared to those from 171 healthy individuals. N-glycans were enzymatically released, chemically derivatized to preserve linkage-specificity of sialic acids and characterized by high resolution mass spectrometry. Logistic regression analysis was used to evaluate associations of specific N-glycan structures as well as N-glycosylation traits with breast cancer. In a case-control comparison three associations were found, namely a lower level of a two triantennary glycans and a higher level of one tetraantennary glycan in cancer patients. Of note, various other N-glycomic signatures that had previously been reported were not replicated in the current cohort. It was further evaluated whether the lack of replication of breast cancer N-glycomic signatures could be partly explained by the heterogenous character of the disease since the studies performed so far were based on cohorts that included diverging subtypes in different numbers. It was found that serum N-glycan profiles differed for the various cancer subtypes that were analyzed in this study.

scholarly journals Self-perceived Risk of Breast Cancer and Screening Behaviors of First-degree Female Relatives of Breast Cancer Patients at the Uganda Cancer Institute, Uganda

2021 ◽  
Author(s):  
Provia Ainembabazi ◽  
Derrick Bary Abila ◽  
Grace Manyangwa ◽  
Godwin Anguzu ◽  
Innocent Mutyaba ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Early Detection ◽  
Cancer Patients ◽  
Breast Cancer Screening ◽  
Perceived Risk ◽  
Breast Cancer Patients ◽  
Perceived Risks ◽  
First Degree Relatives ◽  
Cancer Breast

Abstract Introduction In Uganda, Breast cancer is the most common cancer in females globally. The majority of the patients present with advanced-stage disease at diagnoses and experience high mortality. This underscores the importance of early detection approaches based on awareness of risk factors and self-perceived risks, and symptoms of the disease to promote adoption of risk reduction behaviors and prompt health-seeking respectively. This study assessed the self-perceived risk of breast cancer, and breast cancer screening behaviours among first-degree female relatives of breast cancer patients in Uganda.Methods This was a cross-sectional study employing quantitative approaches for data collection and analyses. First-degree female relatives of patients attending care at Uganda Cancer Institute were recruited consecutively in the study. A pre-tested coded questionnaire was used to collect data on self-perceived risks, breast cancer risks, and breast cancer screening behaviours. Data were collected between March to October 2019. A modified Poisson regression model was used to evaluate factors associated with self-perceived risk of breast cancer and breast cancer risk awareness.ResultsWe enrolled 296 first-degree female relatives from 197 female breast cancer patients. The median age (IQR) was 33 (26-43) years. A majority (60.1%, 178/296) of the participants had a low self-perceived risk of breast cancer. Breast self-examination (55.7%, 165/296) was the most practiced screening method followed by clinical breast examination (n= 64/296, 21.6%), ultrasound scan of the breast (7.8%, 23/296,), and mammogram (3.7%, 11/296). Women aged 35-44 years had a higher self-perceived risk of breast cancer (adjusted Incident Rate Ratio [aIRR]: 1.75, 95%CI: 1.10-2.80), compared to women aged 18-25 years. ConclusionFirst-degree relatives reported a low self-perceived risk of breast cancer. Breast cancer health education especially targeting younger women should emphasize the increased risk of breast cancer in first-degree relatives of patients with breast cancer. There is a need to increase awareness of breast cancer screening methods and their usefulness in the early detection of breast cancer among all women in Uganda.

scholarly journals Literature Review: Social Determinant of Health in Breast Cancer Patients Survival

2021 ◽  
Vol 9 (E) ◽  
pp. 624-628
Author(s):  
Azriful Azriful ◽  
Fatmawaty Mallapiang ◽  
Yessy Kurniati
Keyword(s):  
Breast Cancer ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Cancer Patients ◽  
Social Determinants ◽  
Health Determinants ◽  
Free Text ◽  
Breast Cancer Patients ◽  
Access To Health Services ◽  
Medical Subject Headings

BACKGROUND: Social determinants have an important role in the survival of breast cancer patients. AIM: This article aims to reviews the social determinants that affect the survival of breast cancer patient. METHODS: We searched PubMed and Google Scholar for identifying studies related to this review using free-text terms and Medical Subject Headings terms. Both experimental and observational studies on social determinants of breast cancer patient survival which were published in the English language have been included in this review except expert opinions, commentaries, editorials, and review articles. Ten studies were eligible to be included in review. RESULTS: Social health determinants that play a role in the survival of breast cancer patients are education level, place of residence, socioeconomic status, social environment, racial discrimination, and access to health services. CONCLUSION: Social determinants have an influence on the survival of breast cancer patients, so it is important to pay attention to these factors.

Breast cancer patient access to social work

2016 ◽  
Vol 17 (5) ◽  
pp. 531-543
Author(s):  
Yuko K Abbott
Keyword(s):  
Breast Cancer ◽  
Social Work ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Clinical Area ◽  
Oncology Social Work ◽  
The Impact ◽  
Office Location

Summary This study was conducted to understand the impact of oncology social work office location on breast cancer patients’ access and utilization of social work services. It also explored the current status of oncology social work offices and the perceptions among Association of Oncology Social Work Listserv members. The frequency and types of interventions and referral time were determined retrospectively. Association of Oncology Social Work Listserv members were surveyed. Findings From 461 new breast cancer patient charts, 52 were referred to social work during study period. Face-to-face interventions decreased by 0.8 contact ( p = .0221) and telephone interventions increased by 1.8 contacts ( p = .0293) after social work office was relocated away from clinical area. Referral time to social work services decreased unexpectedly by 14.5 days ( p = .076) after office relocation. Association of Oncology Social Work Listserv survey results identify an office location as possible barrier, though most respondents have a private office in clinical area, accessible to patients. Survey finding is limited due to low response rate. Applications There are many challenges to ensuring timey and effective delivery of social work services to breast cancer patients. Social Ecological framework is used to understand the impacts of office location on access to social work services. Study results suggest that office relocation has had mix impacts on patients. Raising awareness of social worker services among patients early in cancer trajectory is needed for patient empowerment and to ensure access to social work services. Further research is needed to understand barriers, identify effective strategies in order to guide and improve clinical practice.

scholarly journals Literature Review: Teknik Relaksasi untuk Penerimaan Diri Pasien Kanker Payudara

2019 ◽  
Vol 10 (2) ◽  
pp. 298
Author(s):  
Ni Made Merlin ◽  
Anggorowati Anggorowati ◽  
Chandra Bagus Ropyanto ◽  
Antonius Rino Vanchapo
Keyword(s):  
Breast Cancer ◽  
Literature Review ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Cancer Patients ◽  
Relaxation Technique ◽  
Evidence Based ◽  
Relaxation Techniques ◽  
Breast Cancer Patients ◽  
Self Acceptance

<p>Breast cancer patients experience low self-acceptance and some of the experiencing psychological problems but not a lot of research to increasing self-acceptance. Additional intervention is needed to improve the effectiveness to increase self-acceptance. Technique relaxation is especially related because easy and quick to learn, it involves no risk, does not need use or purchased equipment and can be used on its own and immediately to tiredness and ill patients. This paper offers a literature review assessing the implications of previous studies order to create evidence-based decisions about the possibility to use of relaxation techniques with adult breast cancer patient for low self-acceptance. The Science Direct, EBSCOhost, Pubmed, DOAJ, Google Scholar database were searched in 2017 in orders to replied two questions: are relaxation technique effective to increase self-acceptance in breast cancer patients, and implications the previous investigation to future research concerning increase self-acceptance in breast cancer patients? Four articles included in the literature review. The relaxation technique for breast cancer patients with low self-acceptance is statically significant, and good evidence-based to practice. Some use of relaxation techniques in this study needs clarification as to whether it can be used directly or need to learn. Procedures in the collection of data in the articles also need to be assessed. In this literature review explain 4 relaxation technique to use for increasing self-acceptance in breast cancer, there are self-forgiveness, meditation, tai-chi, reflection, prayer, mindfulness. This literature review can be used as the basis for the decision to use relaxation techniques for increasing self-acceptance in the breast cancer patient.</p>

scholarly journals Possible Association of Typhoon Hagibis and the COVID-19 Pandemic on Patient Delay in Breast Cancer Patients: a case report

2021 ◽  
Author(s):  
Yudai Kaneda ◽  
Akihiko Ozaki ◽  
Masahiro Wada ◽  
Tomohiro Kurokawa ◽  
Toyoaki Sawano ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Patient Care ◽  
Cancer Patients ◽  
Initial Presentation ◽  
Breast Cancer Patients ◽  
Cancer Management ◽  
Breast Cancer Management

Little is known on how disasters interact in their impacts on patient care. We experienced a breast cancer patient whose initial presentation was delayed for two years due to the COVID-19 pandemic and Typhoon Hagibis. Increasing awareness is needed on the combined impacts of disasters on breast cancer management.

scholarly journals High miR-30 Expression Associates with Improved Breast Cancer Patient Survival and Treatment Outcome

Cancers ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2907
Author(s):  
Maral Jamshidi ◽  
Rainer Fagerholm ◽  
Taru A. Muranen ◽  
Sippy Kaur ◽  
Swapnil Potdar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Pathway Analysis ◽  
Patient Survival ◽  
Breast Cancer Cell Lines ◽  
Breast Cancer Patients ◽  
Her2 Positive ◽  
Cancer Pathogenesis ◽  
The Impact

Deregulated miRNA expression has been suggested in several stages of breast cancer pathogenesis. We have studied the miR-30 family, in particular miR-30d, in relation to breast cancer patient survival and treatment outcomes. With tumor specimens from 1238 breast cancer patients, we analyzed the association of miR-30d expression with tumor characteristics with the 5-year occurrence of breast cancer-specific death or distant metastasis (BDDM), and with 10-year breast cancer survival (BCS). We conducted a two-stage drug-screen to investigate the impact of miR-30 family members (miR-30a-30e) on sensitivity to doxorubicin and lapatinib in six breast cancer cell lines HCC1937, HCC1954, MDA-MB-361, MCF7, MDA-MB-436 and CAL-120, using drug sensitivity scores (DSS) to compare the miR-30 family mimics to their specific inhibitors. The study was complemented with Ingenuity Pathway Analysis (IPA) with the METABRIC data. We found that while high miR-30d expression is typical for aggressive tumors, it predicts better metastasis-free (pBDDM = 0.035, HR = 0.63, 95% CI = 0.4–0.9) and breast cancer-specific survival (pBCS = 0.018, HR = 0.61, 95% CI = 0.4–0.9), especially in HER2-positive (pBDDM = 0.0009), ER-negative (pBDDM = 0.003), p53-positive (pBDDM = 0.011), and highly proliferating (pBDDM = 0.0004) subgroups, and after adjuvant chemotherapy (pBDDM = 0.035). MiR-30d predicted survival independently of standard prognostic markers (pBDDM = 0.0004). In the drug-screening test, the miR-30 family sensitized the HER2-positive HCC1954 cell line to lapatinib (p < 10–2) and HCC1937, MDA-MB-361, MDA-MB-436 and CAL120 to doxorubicin (p < 10–4) with an opposite impact on MCF7. According to the pathway analysis, the miR-30 family has a suppressive effect on cell motility and metastasis in breast cancer. Our results suggest prognostic and predictive potential for the miR-30 family, which warrants further investigation.

scholarly journals Solitary Bone Metastasis beneath the Shoulder Shield: Coincidence or Cause?

2006 ◽  
Vol 13 (4) ◽  
pp. 121-123
Author(s):  
G. Fan ◽  
E. Sinclair ◽  
M. Christakis ◽  
L. Erhlich ◽  
J. Zubovits ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bone Metastasis ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Cancer Patients ◽  
Locoregional Control ◽  
Breast Cancer Patients ◽  
Solitary Bone Metastasis

Post-mastectomy radiotherapy has been demonstrated to improve locoregional control in breast cancer patients. We report a case involving a 44-year-old breast cancer patient who presented with a solitary bone metastasis in the area beneath the shoulder shield, likely from a coincidental recurrence.

Sign in / Sign up

Export Citation Format

Share Document