scholarly journals The Egyptian formula a New Formula for Prediction of Fetal Birth Weight using Liver Volume Measured by Three-Dimensional Ultrasound (VOCAL System)

2017 ◽  
Vol 4 (2) ◽  
Author(s):  
Haitham Torky
QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
M A El-Kady ◽  
A M Mansour ◽  
M H Ismail

Abstract Background The placenta is the principal influence on fetal birth weight, and it is thought that abnormalities of placental growth may precede abnormalities in fetal growth. Because the placenta may be the first organ to manifest changes of disease in pregnancy, placental features may have a role in screening for pregnancy complications. Aim of the Work The aim this study is to assess the accuracy of placental thickness (estimated by ultrasonography) in predicting fetal weight. Patients and Methods This prospective observational study was conducted at Ain Shams University Maternity Hospital November, 15th, 2016 to November, 1st, 2017. 100 Normal antenatal pregnant women at 24-28 weeks of pregnancy who attended antenatal clinic at the department of obstetrics and gynecology, Ain Shams University Maternity Hospital were recruited, after fulfilling the inclusion and exclusion criteria. Results The predictive rule could estimate actual birth weight with an accuracy of ± 0.450 kg (SEest = 0.450 kg). In visits 1 and 2; ± 0.448 kg (SEest = 0.448 kg) in visit 3. Conclusion The actual birth weight was regressed on the placental thickness using simple linear regression to obtain a predictive rule. There is very weak correlation between the actual neonatal weight and placental thickness. The current study deduced a new formula for correction of EFW using placental thickness which has a promising role to offer in the prediction of birth weight.


2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Paweł Jan Stanirowski ◽  
Agata Majewska ◽  
Michał Lipa ◽  
Dorota Bomba-Opoń ◽  
Mirosław Wielgoś

Abstract Background The aim of the study was to evaluate the ultrasound-derived measurements of the fetal soft-tissue, heart, liver and umbilical cord in pregnancies complicated by gestational (GDM) and type 1 diabetes mellitus (T1DM), and further to assess their applicability in the estimation of the fetal birth-weight and prediction of fetal macrosomia. Methods Measurements were obtained from diet-controlled GDM (GDMG1) (n = 40), insulin-controlled GDM (GDMG2) (n = 40), T1DM (n = 24) and healthy control (n = 40) patients. The following parameters were selected for analysis: fetal sub-scapular fat mass (SSFM), abdominal fat mass (AFM), mid-thigh fat/lean mass (MTFM/MTLM) and inter-ventricular septum (IVS) thicknesses, heart and thorax circumference and area (HeC/HeA; ThC/ThA), liver length (LL), umbilical cord/vein/arteries circumference and area (UmC/UmA; UvC/UvA; UaC/UaA) together with total umbilical vessels (UveA) and Wharton's jelly area (WjA). Regression models were created in order to assess the contribution of selected parameters to fetal birth-weight (FBW) and risk of fetal macrosomia. Results Measurements of the fetal SSFM, AFM, MTFM, MTFM/MTLM ratio, HeC, HeA, IVS, LL, UmC, UmA, UaC, UaA, UveA and WjA were significantly increased among patients with GDMG2/T1DM as compared to GDMG1 and/or control groups (p < .05). The regression analysis revealed that maternal height as well as fetal biparietal diameter, abdominal circumference (AC), AFM and LL measurements were independent predictors of the FBW (p < .05). In addition, increase in the fetal AFM, AC and femur length (FL) was associated with a significant risk of fetal macrosomia occurrence (p < .05). The equation developed for the FBW estimation [FBW(g) = − 2254,942 + 17,204 * FL (mm) + 105,531 * AC (cm) + 131,347 * AFM (mm)] provided significantly lower mean absolute percent error than standard formula in the sub-group of women with T1DM (5.7% vs 9.4%, p < .05). Moreover, new equation including AC, FL and AFM parameters yielded sensitivity of 93.8%, specificity 77.7%, positive predictive value 54.5% and negative predictive value of 97.8% in the prediction of fetal macrosomia. Conclusions Ultrasound measurements of the fetal soft tissue, heart, liver and umbilical cord are significantly increased among women with GDM treated with insulin and T1DM. In addition to standard biometric measurements, parameters, such as AFM, may find application in the management of diabetes-complicated pregnancies.


2017 ◽  
Vol 45 (9) ◽  
Author(s):  
Haitham A. Torky ◽  
Asem A. Moussa ◽  
Ali M. Ahmad ◽  
Osama Dief ◽  
Manar A. Eldesoouky ◽  
...  

AbstractAim of work:To determine whether fetal volume (FV) measured by three-dimensional (3D) ultrasound was able to detect fetuses at risk of low birth weight (primary outcome) and/or preterm labor (secondary outcome).Methods:One hundred pregnant women carrying a singleton living pregnancy who were sure of dates, and had a dating scan, with gestational age between 11 weeks and 13 weeks+6 days coming for routine first trimester nuchal translucency (NT) were examined by both two-dimensional (2D) and 3D ultrasound (Vocal System) for crown-rump length (CRL) and FV then followed up regularly every 4 weeks until 28 weeks then biweekly until 36 weeks then weekly until delivery both clinically and by ultrasound biometry.Findings:Eighty-seven cases had a normal outcome, while the remaining 13 cases had either preterm labor (four cases) or low-birth weight (nine cases). FV positively correlated with CRL (P=0.026), gestational age in weeks (P=0.002), neonatal body weight in grams (P=0.018) and neonatal body length at birth (P=0.04). A mean FV of 8.3 mmConclusion:3D assessment of FV in the first trimester provides an accurate method for predicting pregnancy outcome namely low birth weight and neonatal complications, however, it is a better positive predictor than a negative one.


2018 ◽  
Vol 32 (13) ◽  
pp. 2152-2158 ◽  
Author(s):  
Gunsu Kimyon Comert ◽  
Sertac Esin ◽  
Gamze Sinem Caglar ◽  
Bulent Yirci ◽  
Sedat Ozdemir ◽  
...  

Author(s):  
Yang Yang ◽  
Fang Tang ◽  
Xuezhi Zhao

Background: Preeclampsia (PE) is defined as a salient complication of late pregnancy. microRNAs (miRNAs) have emerged as critical biological regulators in PE. This study determined miR-27b-3p expression in serum of PE patients and investigated its clinical significance in PE. Methods: Totally 130 pregnant women including 90 PE patients (51 mild PE and 39 severe PE) and 40 healthy controls were enrolled in this study. miR-27b-3p expression in the serum of PE patients and healthy controls was detected using RT-qPCR. The correlation among miR-27b-3p expression and 24-h urine protein, systolic blood pressure (SBP), diastolic blood pressure (DBP), serum creatinine, and fetal birth weight was analyzed using Pearson's correlation coefficient. The targeting relationship between miR-27b-3p and PPARG was verified. PPARG protein level in PE patients was detected using ELISA kits. The predictive efficiency of miR-27b-3p and PPARG in PE was analyzed using the receiver operating characteristic (ROC) curve. Results: Compared to normal pregnant women, PE pregnant women, especially severe PE patients had higher miR-27b-3p expression. miR-27b-3p was positively correlated with 24-h urine protein, SBP, DBP, and serum creatinine, but negatively correlated with fetal birth weight. PPARG was poorly expressed in PE patients and negatively correlated with miR-27b-3p. ROC curve showed that both miR-27b-3p and PPARG had good predictive efficacy on PE. Conclusion: miR-27b-3p expression in serum of pregnant women with PE was positively correlated with the severity of PE symptoms, suggesting the involvement of miR-27b-3p in PE occurrence.


2021 ◽  
pp. 1-3
Author(s):  
Sathyan Gnanasigamani ◽  
Sudhakar Vadivel ◽  
Bala Subramaniam ◽  
Sakthivel Raja Ganesan ◽  
Pradeebaa Thiyagarajan ◽  
...  

Background: The Accurate estimation of fetal weight is important in modern obstetrics. Currently, Hadlock's formula is used widely for fetal weight estimation, which includes BPD, AC, FL and HC. The correct plane of measurement of various standard parameters is difcult to obtain especially in third trimester. Hence soft tissue thicknesses of the fetus are tested for correlation with birth weight in this study. Materials & Methods: A prospective observational study conducted among 90 pregnant females referred for Ultrasound examination in the third trimester with an interval from the ultrasound scan to delivery of ≤7 days from 2019 to 2020. Results: The measurements of abdominal, fetal mid-thigh and mid-arm soft tissue thicknesses correlated well with birth weight in a high statistically signicant positive linear relationship. A new regression model developed out of the soft tissue thicknesses(FASTT, FMASTT, FTSTT) correlates better than the Hadlock's model and Sujitkumar Hiwale et al model (For Indian population) based on BPD, HC, AC and FL Conclusion: Ultrasound measurement of soft tissue thickness may prove to be a strong predictor of fetal weight essential for sonographic assessment of pregnancy. They are easy and simple hence fetal soft tissue thickness measurements, both two- and three-dimensional, may prove to be a diagnostic parameter that has as small an error rate as possible, is quick to use and reproducible by different examiners


2021 ◽  
pp. 17-19
Author(s):  
Kumari Ragini ◽  
Amit Kumar ◽  
Reena Kumari ◽  
Debarshi Jana

Objective:This study was to estimate the fetal weight in term pregnancy by clinical methods and ultrasound and to compare the results with actual birth weight (ABW). Material and Methods:This study was conducted at Department of Obstetrics and Gynaecology, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar from December 2019 to May 2020. It was a prospective study covering 200 pregnant women at term gestation. Results: Estimated birth weight by abdominal girth × symphysis fundal height (AG × SFH) formula was closest to the ABW (P = 0.060), as compared to the estimated birth weight by Johnson's formula (P = 0.000) and Hadlock's formula (P = 0.000). Therefore, of the three formulae studied, AG × SFH formula had better predictive value as compared to Johnson's and Hadlock's formulae. The accuracy of AG × SFH (Insler's formula) for estimating the fetal weight at term was found to be comparable to Hadlock's formula (P= 0.104). Conclusion: Clinical estimation of birth weight denitely has a role in the management of labor and delivery. AG × SFH is a simple, easy, costeffective, and universally applicable method to predict fetal birth weight which can be used even by paramedics like midwives and also in centers where ultrasound is not available.


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