Letters to the Editor

PEDIATRICS ◽  
1964 ◽  
Vol 34 (3) ◽  
pp. 435-435
Author(s):  
WILLIAM J. WATERS
Keyword(s):  
Brain Damage ◽  
Letters To The Editor ◽  
Bilirubin Encephalopathy ◽  
Early Signs ◽  
Irreversible Brain Damage ◽  
The Future ◽  
Close Observation ◽  
Neurological Disturbance

Dr. Zoger's point is well taken. We hope to be able to give a satisfactory follow-up report in the future. I believe as Dr. Byers indicated in his article that close observation of the jaundiced infant will help to detect early signs of neurological disturbance. Increasing lethargy and decreasing response of Moro, suck, and grasp should alert the clinician to the possibility of irreversible brain damage (bilirubin encephalopathy).

Instruction Helps and Hinders Young Children’s Feature Learning

2018 ◽  
Author(s):  
Charles Kalish ◽  
Nigel Noll
Keyword(s):  
Young Children ◽  
Feature Learning ◽  
Irrelevant Information ◽  
Diagnostic Feature ◽  
Older Children ◽  
Prediction Task ◽  
Feature Correlation ◽  
The Future

Existing research suggests that adults and older children experience a tradeoff where instruction and feedback help them solve a problem efficiently, but lead them to ignore currently irrelevant information that might be useful in the future. It is unclear whether young children experience the same tradeoff. Eighty-seven children (ages five- to eight-years) and 42 adults participated in supervised feature prediction tasks either with or without an instructional hint. Follow-up tasks assessed learning of feature correlations and feature frequencies. Younger children tended to learn frequencies of both relevant and irrelevant features without instruction, but not the diagnostic feature correlation needed for the prediction task. With instruction, younger children did learn the diagnostic feature correlation, but then failed to learn the frequencies of irrelevant features. Instruction helped older children learn the correlation without limiting attention to frequencies. Adults learned the diagnostic correlation even without instruction, but with instruction no longer learned about irrelevant frequencies. These results indicate that young children do show some costs of learning with instruction characteristic of older children and adults. However, they also receive some of the benefits. The current study illustrates just what those tradeoffs might be, and how they might change over development.

Opening a Group Home

1988 ◽  
Vol 51 (5) ◽  
pp. 160-162 ◽  
Author(s):  
Penelope Voisey
Keyword(s):  
Support Group ◽  
Group Home ◽  
The Future ◽  
Selection Of

This article describes the setting up of a group home in Guildford to accommodate, in two flats, 13 medium-stay patients from Brookwood Hospital. The acquisition of the property, the selection of suitable patients, the initiation of a support group and the activities involved are discussed, as well as the moving arrangements, follow-up and support. Finally, some preliminary suggestions regarding possible improvements for a similar venture in the future are given.

Ischemic neuronal damage after acute subdural hematoma in the rat: effects of pretreatment with a glutamate antagonist

1991 ◽  
Vol 74 (6) ◽  
pp. 944-950 ◽  
Author(s):  
Min-Hsiung Chen ◽  
Ross Bullock ◽  
David I. Graham ◽  
Jimmy D. Miller ◽  
James McCulloch
Keyword(s):  
Brain Damage ◽  
Subdural Hematoma ◽  
Neuronal Damage ◽  
Nmda Receptor Antagonist ◽  
Acute Subdural Hematoma ◽  
Ischemic Brain Damage ◽  
Ischemic Brain ◽  
Content Type ◽  
Irreversible Brain Damage ◽  
Slow Injection

✓ The ability of a competitive N-methyl-D-aspartate (NMDA) receptor antagonist (D-CPP-ene) to reduce irreversible brain damage has been examined in a rodent model of acute subdural hematoma. Acute subdural hematoma was produced by the slow injection of 400 µl homologous blood into the subdural space overlying the parietal cortex in halothane-anesthetized rats. Brain damage was assessed histologically in sections at multiple coronal planes in animals sacrificed 4 hours after induction of the subdural hematoma. Pretreatment with D-CPP-ene (15 mg/kg) significantly reduced the volume of ischemic brain damage produced by the subdural hematoma from 62 ± 8 cu mm (mean ± standard error of the mean) in vehicle-treated control rats to 29 ± 7 cu mm in drug-treated animals. These data demonstrate the anti-ischemic efficacy of NMDA antagonists in an animal model of intracranial hemorrhage in which intracranial pressure is elevated, and suggest that excitotoxic mechanisms (which are susceptible to antagonism by D-CPP-ene) may play a role in the ischemic brain damage which is observed in patients who die after acute subdural hematoma.

Remembering the Past/Anticipating the Future: A Professor From the White Working Class Talks With a Survivor of the Holocaust About Our Troubled World

2017 ◽  
Vol 24 (5) ◽  
pp. 323-337 ◽  
Author(s):  
Carolyn Ellis ◽  
Jerry Rawicki
Keyword(s):  
Working Class ◽  
Collaborative Writing ◽  
Political Climate ◽  
Donald Trump ◽  
The Past ◽  
The Holocaust ◽  
The Future ◽  
White Working Class ◽  
Shed Light

This article extends the research of Jerry Rawicki and Carolyn Ellis who have collaborated for more than eight years on memories and consequences of the Holocaust. Focusing on Jerry’s memories of his experience during the Holocaust, they present dialogues that took place during five recorded interviews and follow-up conversations that reflect on the similarity of Hitler’s seizing of power in the 1930s to the meteoric rise of Donald Trump. Noting how issues of class and race were taking an increasingly prominent role in their conversations and collaborative writing, they also begin to examine discontent in the rural, White working class and Carolyn’s socialization within that community. These dialogues and reflections seek to shed light on the current political climate in America as Carolyn and Jerry struggle to cope with their fears and envision a hopeful path forward for their country.

scholarly journals Neonatal Severe Hyperbilirubinemia Online Registry in Jiangsu Province: protocol for a multicentre, prospective, open, observational cohort study

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e040797
Author(s):  
Qianqian Li ◽  
Xiaoyi Deng ◽  
Junmei Yan ◽  
Xiaofan Sun ◽  
Xiaoyue Dong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Observational Cohort Study ◽  
Jiangsu Province ◽  
Survival Status ◽  
Bilirubin Encephalopathy ◽  
Brainstem Response ◽  
Observational Cohort ◽  
Severe Hyperbilirubinemia

IntroductionSevere hyperbilirubinaemia in newborns can be easily complicated by acute bilirubin encephalopathy or even kernicterus, which could lead to neurological sequelae or death. However, there is no systematic study of the management of severe hyperbilirubinaemia in China. The Neonatal Severe Hyperbilirubinemia Online Registry study aims to investigate the management of jaundice before admission, risk factors and outcomes of severe hyperbilirubinaemia in a real-world setting in China.Methods and analysisThis is a prospective, multicentre, open, observational cohort study. From May 2020 to April 2023, more than 2000 patients with neonatal severe hyperbilirubinaemia from 13 tertiary hospitals in Jiangsu Province will join the study. Demographic data and treatment information will be collected from their clinical data. Management measures for jaundice before admission will be collected by the WeChat applet (called ‘Follow-up of jaundice’) after being provided by the patient’s guardian using a mobile phone. Follow-up data will include cranial MRI examination results, brainstem auditory-evoked potential or automatic auditory brainstem response, physical examination results and Griffiths Development Scales-Chinese at the corrected ages of 3–6 months and 1 and 2 years. Results and conclusions will be recorded using ‘Follow-up of jaundice.’ In-hospital outcomes, including severity of hyperbilirubinaemia (severe, extreme, hazardous), acute bilirubin encephalopathy (mild, moderate, severe) and survival status (death or survival), will be collected at discharge. Follow-up outcomes will include loss to follow-up, survival status and kernicterus (yes or no) at 2 years. The research will enhance our comprehensive knowledge of jaundice management before admission, risk factors and outcomes of severe hyperbilirubinaemia in China, which will ultimately help to reduce the incidence of neonatal severe hyperbilirubinaemia.Ethics and disseminationOur protocol has been approved by the Medical Ethics Committee of Nanjing Maternity and Child Health Care Hospital. We will present our findings at national conferences and peer-reviewed paediatrics journals.Trial registration numberNCT04251286.

Letters to the Editor

PEDIATRICS ◽  
1971 ◽  
Vol 47 (2) ◽  
pp. 471-472
Author(s):  
Carl C. Fischer
Keyword(s):  
Health Care ◽  
Delivery Of Health Care ◽  
Executive Board ◽  
Pediatric Practice ◽  
Letters To The Editor ◽  
The Future ◽  
The Status

We asked Dr. Carl Fischer, as the most appropriate representative of the Academy, to comment. He did so, as follows: On reading Doctor Schulman's letter of October 13, 1970, I note that his concerns are the same as those felt by the Executive Board when it directed the Council on Pediatric Practice to make a 2-year study of the status of the delivery of health care to children and prepare a report with the best possible recommendations for the future.

Letters to the Editor

PEDIATRICS ◽  
1980 ◽  
Vol 66 (1) ◽  
pp. 152-152
Author(s):  
Stanley A. Cohen ◽  
Kristy Hendricks ◽  
W. Allan Walker
Keyword(s):  
Total Population ◽  
Letters To The Editor ◽  
Attrition Bias ◽  
Dietary Records

Dr. Forsyth's letter and insightful comments are appreciated. It provides the impetus and forum to clarify some potentially confusing statements in our recent publication. A statistical attrition bias is possible since only 26 complete dietary records were available for follow-up. The patients were drawn from a total population of 500 outpatients seen in our clinic over a 2½-year period. They were examined by various physicians and dieticians during that time. Although vigorous attempts were made to obtain initial and follow-up data on all of the patients with chronic nonspecific diarrhea, those data were not obtainable from all of the patients.

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